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M. thermoresistible (build 8) TH_0172 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LYSR-FAMILY)
coordinates: 380767 - 381717
length: 317

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0172-100% (317)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LYSR-FAMILY)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0384-1e-12973.52% (321) LysR family transcriptional regulator
M. gilvum PYR-GCKMflv_1833-6e-0924.86% (181) LysR family transcriptional regulator
M. tuberculosis H37RvRv0377-1e-12873.21% (321) LysR family transcriptional regulator
M. leprae Br4923MLBr_02041oxyR7e-0725.93% (189) putative LysR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4409-2e-0826.44% (261) hydrogen peroxide-inducible genes activator
M. marinum MMMAR_0653-1e-12872.90% (321) LysR family transcriptional regulator
M. avium 104MAV_4979-4e-1028.98% (176) transcriptional regulator, LysR family protein, putative
M. smegmatis MC2 155MSMEG_0742-1e-12774.21% (318) transcriptional regulatory protein
M. ulcerans Agy99MUL_0119-1e-12171.61% (310) LysR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1027-5e-0927.46% (193) LysR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0653|M.marinum_M               -----------------MTPAQLRAYSAVVRLGSVRAAATELGLSDAGVS
MUL_0119|M.ulcerans_Agy99           ----------------------------MVRLGSVRAAATELGLSDAGVS
Mb0384|M.bovis_AF2122/97            -----------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVS
Rv0377|M.tuberculosis_H37Rv         -----------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVS
MSMEG_0742|M.smegmatis_MC2_155      -----------------MTPAQLRAFSAVVRLGSVRAAAEELGVSDAGVS
TH_0172|M.thermoresistible__bu      -----------------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGIS
MLBr_02041|M.leprae_Br4923          ----------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLS
MAB_4409|M.abscessus_ATCC_1997      ----------MSDRSYQPTVVGLRAFVAIARKRHFGSAAGELGVSQPSLS
Mvan_1027|M.vanbaalenii_PYR-1       ----------------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLS
Mflv_1833|M.gilvum_PYR-GCK          -----------------MDTHRLKYFLRIAEEGSITRAASLLGMAQPALS
MAV_4979|M.avium_104                MLLAVSAVGGPESRCVMATLLQLKAFLAVVDQGGFTAASRSLGMSQPAVS
                                                                :.    .  *:  * : :. :*

MMAR_0653|M.marinum_M               MHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG-LQQQTAIEV
MUL_0119|M.ulcerans_Agy99           MHVAALRKELDDPLFTRTGAGLAFTPGGLRLASGAVEILG-LQQQTAIEV
Mb0384|M.bovis_AF2122/97            MHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG-LQQQTAIEV
Rv0377|M.tuberculosis_H37Rv         MHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG-LQQQTAIEV
MSMEG_0742|M.smegmatis_MC2_155      MHVAQLRKELDDPLFTRTASGLAFTPGGLRLASRAVEILG-LQQQTAIEV
TH_0172|M.thermoresistible__bu      MHIAQLRKELDDPLFHRTKNGLSFTPGGLRLASRAVDILG-LQRQTAIEV
MLBr_02041|M.leprae_Br4923          QALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAA
MAB_4409|M.abscessus_ATCC_1997      QALSMLEEGLGVRLVERNTRKVLLTPEGDALLEKAISALNAVDEFTSAAS
Mvan_1027|M.vanbaalenii_PYR-1       RQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVK
Mflv_1833|M.gilvum_PYR-GCK          RQLQLLEEDLGVALFRRNRRGVELTDAGERLRSSTAAPLRQLELAVQYAA
MAV_4979|M.avium_104                RAVAGLERELGSPLLIRHRDRILLNAPGKRALAHARSAVRHLDQMRAEVS
                                      :  *.  *.  *. *    : ..  *      :   :   :       

MMAR_0653|M.marinum_M               TEAAHGRRLLRIAASSTFAEHAAPGLIELFSSRADDLSVELSVHPTSQFR
MUL_0119|M.ulcerans_Agy99           TEAAHGRRLLRIAASSTFAEHAAPGLIELFSSRADDLSVELSVHPTSQFR
Mb0384|M.bovis_AF2122/97            TEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFR
Rv0377|M.tuberculosis_H37Rv         TEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFR
MSMEG_0742|M.smegmatis_MC2_155      TEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPARQFG
TH_0172|M.thermoresistible__bu      TEAAHGRRLLRIAASHAFAEHAAPGLIDLFSSRADDLSVELTVEPVSRFR
MLBr_02041|M.leprae_Br4923          GESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLL
MAB_4409|M.abscessus_ATCC_1997      GVRDPFAQTLRLGLIPTVAPYVLPMVLSGLSREFPEMSLRVTEDQTHRLL
Mvan_1027|M.vanbaalenii_PYR-1       RIPAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVKLDLREMVTAAQI
Mflv_1833|M.gilvum_PYR-GCK          FPLARLKRAMLIGIPESAIDVLAAPLMTRLGSAFPDAQFAVTVGSTDHLV
MAV_4979|M.avium_104                -AAAKLRGTLRIASLPYTTELLIAPQLQKFSERHPSVEIRVLEGGEPEIR
                                             : :.          .  :           . :         

MMAR_0653|M.marinum_M               DLICSRAVDIAIGPASESSIGSDTSLFVRPFLKYQIITVVAPNSPLAVG-
MUL_0119|M.ulcerans_Agy99           DLICARAVDIAIGPASESSIGSDTSLFVRPFLKYQIITVVAPNSPLAVG-
Mb0384|M.bovis_AF2122/97            ELICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAG-
Rv0377|M.tuberculosis_H37Rv         ELICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAG-
MSMEG_0742|M.smegmatis_MC2_155      HLITSRAVDIALGPAAP----ADPNLVVRAFLKYQIITVTTPDNALLER-
TH_0172|M.thermoresistible__bu      DLLESRAVDVTLGPAVRE---PGPAIVVRPFLNYQIIAVTSPSNPLAAA-
MLBr_02041|M.leprae_Br4923          TALREGALDAAMIALPVET----AGIAEIPIYDEDFVLALPPGHPLSGKR
MAB_4409|M.abscessus_ATCC_1997      RSLSDGTLDVAVMALPVQT----QGMAEIPMYREDFVLALPSGHPLAGSK
Mvan_1027|M.vanbaalenii_PYR-1       EGLMTGELDLGMARPPLKR----PGLVSRPLLHEQLLAALPEGHPLADMT
Mflv_1833|M.gilvum_PYR-GCK          EAMLKGSVDIALINPVPDD-----RVFYREILTEEFVLVGGPDSPLEPEK
MAV_4979|M.avium_104                DWLDLGAADAGVISLPATG------LSAAFLAAQDMVAVLPSEHRLAAFS
                                      :     *  :             :    :   ::: .      *    

MMAR_0653|M.marinum_M               --IPTPSLLRQQQWMLGPPAGSVAGEIATMLRDLAIPESQQRIFQSDA-A
MUL_0119|M.ulcerans_Agy99           --IPTPSLLRQQQWMLGPPAGSVAGEIATMLRDLAIPESQQRIFQSDA-A
Mb0384|M.bovis_AF2122/97            --IPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQSDA-A
Rv0377|M.tuberculosis_H37Rv         --IPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQSDA-A
MSMEG_0742|M.smegmatis_MC2_155      --GVTPASLREQPWQLGPSGGNADGEIAAMLRALAIPEARQRIFQSDA-A
TH_0172|M.thermoresistible__bu      --TPTIAQLRAQSWMLGPSAGGIDGDVAAMLRRLEIPEAAQRIFQSDS-A
MLBr_02041|M.leprae_Br4923          -RVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLA-T
MAB_4409|M.abscessus_ATCC_1997      -NVEPADLADMPLLLLDEGHCLRDQALEVCQLAGVRPDLGHTRAASLA-T
Mvan_1027|M.vanbaalenii_PYR-1       RELTLIDLDGQDFVMYSPVQARYFNELLISTFTIAGTTPRYVQYVTQVHT
Mflv_1833|M.gilvum_PYR-GCK          -PLQFADLVELPLVVPRSTTGLGQALYNAALRAKVTIDYRITTDSTRV--
MAV_4979|M.avium_104                -EVHYADLAKEP--FIRSTGGCAHVFMAVADQVGVEFDVAFEAHGLMA--
                                                                                      

MMAR_0653|M.marinum_M               ALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAGEWCVATLPPA
MUL_0119|M.ulcerans_Agy99           ALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAGEWCVATLPPA
Mb0384|M.bovis_AF2122/97            ALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPS
Rv0377|M.tuberculosis_H37Rv         ALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPS
MSMEG_0742|M.smegmatis_MC2_155      ALEEVRRVGGVTPTIGFAVAKDLAGGRLAQVKGPGLQVGGEWFATTLPAS
TH_0172|M.thermoresistible__bu      AQEEVQRIGGVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSA
MLBr_02041|M.leprae_Br4923          AVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSAS
MAB_4409|M.abscessus_ATCC_1997      AVQCVEGGLGVTLIPGTAVTAETASGGLATATFAAPVPGRRIGLVYRAIS
Mvan_1027|M.vanbaalenii_PYR-1       MLVLVRSGIGIALVPASAATLHPEG-----VVFRTIGAFRERPVELDAVW
Mflv_1833|M.gilvum_PYR-GCK          MVCLIESGLAYGVLPLSACGREFAESRLRYSRICEPVLTQQLGVAATEQL
MAV_4979|M.avium_104                VLEIVTAGLGVSIVPVAAVARPRAG---IAVKRLVPKTTRNLAVAVSASA
                                        :    .       *                      .         

MMAR_0653|M.marinum_M               AR-QPAVSELVRFITTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
MUL_0119|M.ulcerans_Agy99           AR-QPAVSELVRFITTPRCIQAMIRGSGVGVTRFRPKMHVTLWS
Mb0384|M.bovis_AF2122/97            AR-QPAVSELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv         AR-QPAVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
MSMEG_0742|M.smegmatis_MC2_155      AR-QPAVSELLRFITTPRCTQAMIRGSGVGVSRFRPKVHVTLWS
TH_0172|M.thermoresistible__bu      AR-QPAASELVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
MLBr_02041|M.leprae_Br4923          GR-SASYRQIAKIIGELISTEHHVRLVA----------------
MAB_4409|M.abscessus_ATCC_1997      AR-EDAYRRLAELLTRLVSAVHPVTADAA---------------
Mvan_1027|M.vanbaalenii_PYR-1       RG-DSTNPALLRVLKDVLPQQEWTT-------------------
Mflv_1833|M.gilvum_PYR-GCK          DLPRELVVKVGNALREEIAALIRSGSWRADLLSPEPWSPRRV--
MAV_4979|M.avium_104                GS-------AARAFLEQIAALDGSERAGA---------------
                                                 :