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TDHSLNGKTVLITGGGKNLGGLIARDLAANGAGAIAIHYNSPSSKDAAEETVAAVQAAGAKAVAFQGDLT TGDAVSKLFADTVAAVGRPDIAINTVGKVIKKPFTEITEEEYDSASAVNAKSAFLFLKEAGKHVNDNGKI VTLVTSLLGAYTPFYAAYAGTKAPVEHFTRAASKEYGERGISVTAVGPGPMDTPFFYPAEGEDAVAYHKT AAALSPFSKTGLTDIEDIAPFIRFLVSDGWWITGQTILINGGYTTK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4657c | - | - | 100% (257) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_3426c | - | 2e-57 | 42.86% (252) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0827 | - | 1e-25 | 31.50% (254) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 4e-18 | 28.57% (259) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1569 | - | 2e-21 | 29.80% (255) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0927c | - | 4e-18 | 28.57% (259) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 8e-14 | 23.79% (248) | 3-oxoacyl- |
| M. marinum M | MMAR_4756 | - | 4e-21 | 31.25% (256) | oxidoreductase |
| M. avium 104 | MAV_1395 | - | 9e-25 | 32.24% (245) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4330 | - | 3e-77 | 57.14% (252) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3122 | - | 1e-71 | 53.88% (245) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_0327 | - | 7e-21 | 30.20% (255) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5843 | - | 4e-26 | 31.35% (252) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4330|M.smegmatis_MC2_155 ---------------MSKLEGKSAVVAAGAKNLGGLISTTLASRGVN-VA
TH_3122|M.thermoresistible__bu -------------------------VAAGAKNLGGLISTTLAERGVN-VA
MAB_4657c|M.abscessus_ATCC_199 -------------MTDHSLNGKTVLITGGGKNLGGLIARDLAANGAGAIA
Mvan_5843|M.vanbaalenii_PYR-1 -------------MSTAPLAGKRALVTGGSRGIGAEIVRRLAADGAA---
Mb0950c|M.bovis_AF2122/97 -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
Rv0927c|M.tuberculosis_H37Rv -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
Mflv_1569|M.gilvum_PYR-GCK --------------MLLSLVDRTVLVTGGGSGIGKGVAAAVVASGGNVVL
MMAR_4756|M.marinum_M ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASVAI
MUL_0327|M.ulcerans_Agy99 ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAV_1395|M.avium_104 ---MAVVTGGGSGIGR-AIVER--LAHDGHR-----VAVLDVNEEAAEKV
. : .
MSMEG_4330|M.smegmatis_MC2_155 VHYNSASTEADADKTVAAVQDAGVKAVKVQGDLTVPANVEKLFDTAIDAF
TH_3122|M.thermoresistible__bu VHYHSAATEPDADKTVAAVEATGARAIKVQGDLTVPANVTRLFDATVEAF
MAB_4657c|M.abscessus_ATCC_199 IHYNSPSSKDAAEETVAAVQAAGAKAVAFQGDLTTGDAVSKLFADTVAAV
Mvan_5843|M.vanbaalenii_PYR-1 VAFTYAASAAHAEKVVAEVAASGGEAVAIRADSADPTQVADAVEQTVAEL
Mb0950c|M.bovis_AF2122/97 ASRTSSELDAVAEQIRAAG----RRAHTVAADLAHPEVTAQLAGQAVGAF
Rv0927c|M.tuberculosis_H37Rv ASRTSSELDAVAEQIRAAG----RRAHTVAADLAHPEVTAQLAGQAVGAF
Mflv_1569|M.gilvum_PYR-GCK AGRNADKLAAAAEEITAQSGDGAGEVMYEPADVTDEDAVTRLVQAATGWR
MMAR_4756|M.marinum_M WERDPQTCAQAAAELGGLG---------IATDVRSGDQVDAALQRTQAEL
MUL_0327|M.ulcerans_Agy99 WERDPQTCAQAAAELGGLG---------IATDVRSGDQVDAALQRTQAEL
MLBr_01807|M.leprae_Br4923 THR------ASVVPDWFFG---------VECDVTDNDAIGAAFKAVEEHQ
MAV_1395|M.avium_104 AAR------VAADGAHAIA---------VPTDVAESASVAAAFESVRRAL
. * .
MSMEG_4330|M.smegmatis_MC2_155 GGVDIAINTVGKVLRK-PIAETTEAEYDSMFDINSKAAYFFLQQAGKRLN
TH_3122|M.thermoresistible__bu GGVDIAVNTVGRVLRK-PIVETTEAEYDAMFDINAKAAYFFLQEAGKRLN
MAB_4657c|M.abscessus_ATCC_199 GRPDIAINTVGKVIKK-PFTEITEEEYDSASAVNAKSAFLFLKEAGKHVN
Mvan_5843|M.vanbaalenii_PYR-1 GGLDILVNNSAVAHIA-PIDDFPAEEFDRLVAINIGGVYWAVRSAIRYLS
Mb0950c|M.bovis_AF2122/97 GKLDIVVNNVGGTMPN-TLLSTSTKDLADAFAFNVGTAHALTVAAVPLML
Rv0927c|M.tuberculosis_H37Rv GKLDIVVNNVGGTMPN-TLLSTSTKDLADAFAFNVGTAHALTVAAVPLML
Mflv_1569|M.gilvum_PYR-GCK GRLDAVVHSAGGSETIGPLTQVDSAAWRNTVDLNVNGTMYVLKHAAREMV
MMAR_4756|M.marinum_M GEVTILVNNVGGVFWS-PLLQTSEKGWDALYRSNLGHVLLCTQRVARRLV
MUL_0327|M.ulcerans_Agy99 GAVTILVNNVGGVFWS-PLLQTSEKGWDALYRSNLGHVLLCTQRVARRLV
MLBr_01807|M.leprae_Br4923 GPVEVLVANAGITSDM-LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
MAV_1395|M.avium_104 GSVQVLVTSAAITGFK-PFAEITIEDWNRHLAVNLTGTFLCLQAALPDMV
* : . . : * . . :
MSMEG_4330|M.smegmatis_MC2_155 DN--GSITTIVTSLLAAYT-DGYSTYAGSKSPVEHFTRAASKEFGVRGIN
TH_3122|M.thermoresistible__bu DG--GSVVTILTALLAAFT-DGYSTYAGAKSPVEHFTRAAAKEFAPRQIS
MAB_4657c|M.abscessus_ATCC_199 DN--GKIVTLVTSLLGAYT-PFYAAYAGTKAPVEHFTRAASKEYGERGIS
Mvan_5843|M.vanbaalenii_PYR-1 EG--ARIINIGSINADRIPGPGLSVYGMTKGAVSSFTRGLARDLGPRGIT
Mb0950c|M.bovis_AF2122/97 EHSGGGSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VR
Rv0927c|M.tuberculosis_H37Rv EHSGGGSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VR
Mflv_1569|M.gilvum_PYR-GCK RG-GGGAFIGISSIASSNTHRWFGAYGPSKAALDHLMMVAADELGPSSVR
MMAR_4756|M.marinum_M AAELPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIR
MUL_0327|M.ulcerans_Agy99 AAGLPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIR
MLBr_01807|M.leprae_Br4923 KQ-RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSIT
MAV_1395|M.avium_104 EA-GWGRVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAHGIT
. *. :*. : : : :
MSMEG_4330|M.smegmatis_MC2_155 VNNIAPGPMDTPFFYPEETPERVEFHKSQAMGN-----RLTDIGDIAPLA
TH_3122|M.thermoresistible__bu VNNVAPGPMDTPFFYGQETPERVTFHKSQGLGN-----RLTRIEDIAPLV
MAB_4657c|M.abscessus_ATCC_199 VTAVGPGPMDTPFFYPAEGEDAVAYHKTAAALSPFSKTGLTDIEDIAPFI
Mvan_5843|M.vanbaalenii_PYR-1 VNNVQPGPIDTDAN-PDDGAFAESLKQVVAQGR------YGHTSDVASLV
Mb0950c|M.bovis_AF2122/97 VNAIAPGSILTSALEVVAAN--DELRAPMEQATPLR--RLGDPVDIAAAA
Rv0927c|M.tuberculosis_H37Rv VNAIAPGSILTSALEVVAAN--DELRAPMEQATPLR--RLGDPVDIAAAA
Mflv_1569|M.gilvum_PYR-GCK VNGIRPGLTKTDMVAPILDT--PAVSDDYAACTPLP--RVGEVEDIANLA
MMAR_4756|M.marinum_M VNAIAPDITMTEGLAQLGGA--AALER-IGSLVPLG--RPGDIDEIASVA
MUL_0327|M.ulcerans_Agy99 VNAIAPDITMTEGLAQLGGA--AALER-IGSLVPLG--RPGDVDEIASVA
MLBr_01807|M.leprae_Br4923 ANVVAPGFIDTEMTRAMDSK----YQEAALQAIPLG--RIGAVEEIAGAV
MAV_1395|M.avium_104 ANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVG--RLGTGEDIAAAC
.. : * * ::*
MSMEG_4330|M.smegmatis_MC2_155 VFLAD-EGHWINGQTLFTNGGYTTR------------------------
TH_3122|M.thermoresistible__bu AFLTD-EGHWITGQTIFANGGYTTR------------------------
MAB_4657c|M.abscessus_ATCC_199 RFLVS-DGWWITGQTILINGGYTTK------------------------
Mvan_5843|M.vanbaalenii_PYR-1 SFLAGPESGYITGAHLNVDGGFTV-------------------------
Mb0950c|M.bovis_AF2122/97 VYLASPAGSFLTGKTLEVDGGLTF---PNLDLPIPDL------------
Rv0927c|M.tuberculosis_H37Rv VYLASPAGSFLTGKTLEVDGGLTF---PNLDLPIPDL------------
Mflv_1569|M.gilvum_PYR-GCK VFLLSDAASFITGQVINVDGGHGLRRGPDLSGMLEPLFGADGLRGVVAE
MMAR_4756|M.marinum_M VFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG-------
MUL_0327|M.ulcerans_Agy99 VFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG-------
MLBr_01807|M.leprae_Br4923 SFLASEDAGYISGAVIPVDGGLGMGH-----------------------
MAV_1395|M.avium_104 AFLCSDEAGYITGQIIGVNGGEVI-------------------------
:* . . ::.* : :**