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VDIPHTIDPVQPYRPQEQPLRGKVAVITGASANMGAALARTLAQDGAQVVVHYRSDSKAQQAERVVRQIQ ESGSDAVSFQADLSVPENCTKLADAAFEAFGRWDILINTAGMIVRKPLADITEDEYDGVFNANAKTVFFM MREAARRMADNGRILSFVTTMVGALAPTYSAYAGSKAPVEHFTKALAKEVGGRGITANCIAPGPLQTSFF YPAESDENIAWLESMSINGQIGRGDDILPVARLLVLPESGWTTAQTIFVNGGIISTIN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3426c | - | - | 100% (269) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_4657c | - | 3e-57 | 42.86% (252) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0827 | - | 5e-29 | 33.74% (246) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 6e-25 | 32.26% (248) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2415 | - | 1e-26 | 30.65% (261) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0927c | - | 6e-25 | 32.26% (248) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-18 | 27.17% (254) | 3-oxoacyl- |
| M. marinum M | MMAR_4581 | - | 3e-25 | 33.06% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1046 | - | 5e-27 | 33.47% (248) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4330 | - | 7e-60 | 45.27% (243) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3122 | - | 5e-56 | 41.95% (236) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4442 | - | 1e-24 | 32.66% (248) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5843 | - | 5e-32 | 33.06% (248) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4330|M.smegmatis_MC2_155 -----------------MSKLEGKSAVVAAGAK--NLGGLISTTLASRGV
TH_3122|M.thermoresistible__bu ---------------------------VAAGAK--NLGGLISTTLAERGV
MAB_3426c|M.abscessus_ATCC_199 MVDIPHTIDPVQPYRPQEQPLRGKVAVITGASA--NMGAALARTLAQDGA
MMAR_4581|M.marinum_M -------------MILDRFRLDDQVAVITGGGR--GLGAAIALAFAEAGA
MUL_4442|M.ulcerans_Agy99 -------------MILDRFRLDDQVAVITGGGR--GFGAAIALAFAEAGA
MAV_1046|M.avium_104 -------------MILDRFRLDDKVAVITGAGR--GLGAAIAVAFAEAGA
Mb0950c|M.bovis_AF2122/97 -------------MILDMFRLDDKVAVITGGGR--GLGAAIALAFAQAGA
Rv0927c|M.tuberculosis_H37Rv -------------MILDMFRLDDKVAVITGGGR--GLGAAIALAFAQAGA
Mflv_2415|M.gilvum_PYR-GCK -----------------MTELAGKVAVVTGGAS--GIGRGIAARFAAEGA
Mvan_5843|M.vanbaalenii_PYR-1 ---------------MSTAPLAGKRALVTGGSR--GIGAEIVRRLAADGA
MLBr_01807|M.leprae_Br4923 -----------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGI
.. . .. : . *
MSMEG_4330|M.smegmatis_MC2_155 NVAVHYNSASTEADADKTVAAVQDAGVKAVKVQGDLTVPANVEKLFDTAI
TH_3122|M.thermoresistible__bu NVAVHYHSAATEPDADKTVAAVEATGARAIKVQGDLTVPANVTRLFDATV
MAB_3426c|M.abscessus_ATCC_199 QVVVHYRSDSKAQQAERVVRQIQESGSDAVSFQADLSVPENCTKLADAAF
MMAR_4581|M.marinum_M DVVIASRTQS---QLDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAV
MUL_4442|M.ulcerans_Agy99 DVVIASRTQS---QLDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAV
MAV_1046|M.avium_104 DVLIASRTES---QLEAVAEQVRAAGRRAHVVAADLAHPESTAELAGRAV
Mb0950c|M.bovis_AF2122/97 DVLIASRTSS---ELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAV
Rv0927c|M.tuberculosis_H37Rv DVLIASRTSS---ELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAV
Mflv_2415|M.gilvum_PYR-GCK AVVIADVRDD---LGEALVRELNESGAKTVYRHTDVGDQAQVADLVSSTV
Mvan_5843|M.vanbaalenii_PYR-1 AVAFTYAASA--AHAEKVVAEVAASGGEAVAIRADSADPTQVADAVEQTV
MLBr_01807|M.leprae_Br4923 GLAVARRLVADG-HRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVE
: . . * .
MSMEG_4330|M.smegmatis_MC2_155 DAFGGVDIAINTVGKVLRK--PIAETTEAEYDSMFDINSKAAYFFLQQAG
TH_3122|M.thermoresistible__bu EAFGGVDIAVNTVGRVLRK--PIVETTEAEYDAMFDINAKAAYFFLQEAG
MAB_3426c|M.abscessus_ATCC_199 EAFGRWDILINTAGMIVRK--PLADITEDEYDGVFNANAKTVFFMMREAA
MMAR_4581|M.marinum_M EAFGRLDIVVNNVGGTMPN--TLLTTSTKDLKDAFTFNVATAHALTVAAV
MUL_4442|M.ulcerans_Agy99 EAFGRLDIVVNNVGGTMPN--TLLTTSTKDLKDAFTFNVATAHALTVAAV
MAV_1046|M.avium_104 EAFGKLDIVVNNVGGTMPN--TLLTTSTKDLKDAFTFNVATAHALTVAAV
Mb0950c|M.bovis_AF2122/97 GAFGKLDIVVNNVGGTMPN--TLLSTSTKDLADAFAFNVGTAHALTVAAV
Rv0927c|M.tuberculosis_H37Rv GAFGKLDIVVNNVGGTMPN--TLLSTSTKDLADAFAFNVGTAHALTVAAV
Mflv_2415|M.gilvum_PYR-GCK ETFGALNVMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAA
Mvan_5843|M.vanbaalenii_PYR-1 AELGGLDILVNNSAVAHIA--PIDDFPAEEFDRLVAINIGGVYWAVRSAI
MLBr_01807|M.leprae_Br4923 EHQGPVEVLVANAGITSDM--LIMRMSEEQFQKVIDVNLTGVFRVAKLAS
* :: : . . : : . * . *
MSMEG_4330|M.smegmatis_MC2_155 KRLNDN---GSITTIVTS-LLAAYTDGYSTYAGSKSPVEHFTRAASKEFG
TH_3122|M.thermoresistible__bu KRLNDG---GSVVTILTA-LLAAFTDGYSTYAGAKSPVEHFTRAAAKEFA
MAB_3426c|M.abscessus_ATCC_199 RRMADN---GRILSFVTT-MVGALAPTYSAYAGSKAPVEHFTKALAKEVG
MMAR_4581|M.marinum_M PLMLEHSGGGSIINITST-MGRVAGRGFAAYGTAKAALAHYTRLAALDLC
MUL_4442|M.ulcerans_Agy99 PLMLEHSGGGGIINITST-MGRVAGRGFAAYGTAKVALAHYTRLAALDLC
MAV_1046|M.avium_104 PLMLEHSGGGNIINITST-MGRLAGRGFAAYGTAKAALSHYTRLTALDLC
Mb0950c|M.bovis_AF2122/97 PLMLEHSGGGSVINISST-MGRLAARGFAAYGTAKAALAHYTRLAALDLC
Rv0927c|M.tuberculosis_H37Rv PLMLEHSGGGSVINISST-MGRLAARGFAAYGTAKAALAHYTRLAALDLC
Mflv_2415|M.gilvum_PYR-GCK RHMADH-GGGSVINLGSI-GGIQAGGGVSTYRASKAAIIHFTKCAAIELA
Mvan_5843|M.vanbaalenii_PYR-1 RYLSEG---ARIINIGSINADRIPGPGLSVYGMTKGAVSSFTRGLARDLG
MLBr_01807|M.leprae_Br4923 RNMIKQR-FGRYIFMGSV-VGLSGVPGQANYAASKSGLIGMARSLARELG
: . . : : : * :* : :: : :.
MSMEG_4330|M.smegmatis_MC2_155 VRGINVNNIAPGPMDTPFFYPEETPER-----------VEFHKSQAMGNR
TH_3122|M.thermoresistible__bu PRQISVNNVAPGPMDTPFFYGQETPER-----------VTFHKSQGLGNR
MAB_3426c|M.abscessus_ATCC_199 GRGITANCIAPGPLQTSFFYPAESDEN-----------IAWLESMSINGQ
MMAR_4581|M.marinum_M P-RIRVNAIAPGSILTSALEVVAANDE----------LRAPMEQATPLRR
MUL_4442|M.ulcerans_Agy99 P-RIRVNAIAPGSILTSALEVVAANDE----------LRAPMEQATPLRR
MAV_1046|M.avium_104 P-RIRVNAIAPGSILTSALDVVASNDE----------LRAPMEKATPLRR
Mb0950c|M.bovis_AF2122/97 P-RVRVNAIAPGSILTSALEVVAANDE----------LRAPMEQATPLRR
Rv0927c|M.tuberculosis_H37Rv P-RVRVNAIAPGSILTSALEVVAANDE----------LRAPMEQATPLRR
Mflv_2415|M.gilvum_PYR-GCK HYEVRVNCLAPGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKR
Mvan_5843|M.vanbaalenii_PYR-1 PRGITVNNVQPGPIDTDANPDDGAFAES-------------LKQVVAQGR
MLBr_01807|M.leprae_Br4923 SRSITANVVAPGFIDTEMTRAMDSKYQ------------EAALQAIPLGR
: .* : ** : * : . :
MSMEG_4330|M.smegmatis_MC2_155 LTDIGDIAPLAVFLAD-EGHWINGQTLFTNGGYTTR-----------
TH_3122|M.thermoresistible__bu LTRIEDIAPLVAFLTD-EGHWITGQTIFANGGYTTR-----------
MAB_3426c|M.abscessus_ATCC_199 IGRGDDILPVARLLVLPESGWTTAQTIFVNGGIISTIN---------
MMAR_4581|M.marinum_M LGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTHPNLDIPVPDL--
MUL_4442|M.ulcerans_Agy99 LGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTHPNLDIPVPDL--
MAV_1046|M.avium_104 LGDPVDIASAAVYLASPAGEFLTGKTLEVDGGLTYPNLDIPVPDL--
Mb0950c|M.bovis_AF2122/97 LGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL--
Rv0927c|M.tuberculosis_H37Rv LGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL--
Mflv_2415|M.gilvum_PYR-GCK EGTADDVAEAALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ
Mvan_5843|M.vanbaalenii_PYR-1 YGHTSDVASLVSFLAGPESGYITGAHLNVDGGFTV------------
MLBr_01807|M.leprae_Br4923 IGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH----------
:: . *. . : .. : :**