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AIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASVAIWERDPQTCAQAAAELGGLGIATDVRSGDQV DAALQRTQAELGEVTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAELPGSIMA ITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNAIAPDITMTEGLAQLGGAAALERIGSLV PLGRPGDIDEIASVAVFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4756 | - | - | 100% (268) | oxidoreductase |
| M. marinum M | MMAR_2592 | - | 4e-46 | 41.47% (258) | short chain dehydrogenase |
| M. marinum M | MMAR_0306 | - | 5e-35 | 37.45% (259) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 3e-34 | 37.40% (246) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 1e-104 | 70.79% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3559c | - | 2e-34 | 36.63% (243) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-26 | 32.77% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 3e-35 | 35.80% (243) | Short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_0894 | - | 1e-117 | 76.78% (267) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_4850 | - | 1e-105 | 69.40% (268) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3505 | - | 1e-103 | 67.91% (268) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0327 | - | 1e-148 | 98.13% (268) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4228 | - | 1e-105 | 70.79% (267) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 ---MASLLN-----------ARTAVITGGA-QGLGLAIGQRFVAEGARVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGN-RGIGLAVARRLVADGHRVA
MMAR_4756|M.marinum_M ---MAIDPA------DVLLNGRVAVVTGAG-SGIGRGVAAGLAAFGASVA
MUL_0327|M.ulcerans_Agy99 ---MAIDPA------DVLLNGRVAVVTGAG-SGIGRGVAAGLAAFGASMA
MAV_0894|M.avium_104 ---MAIDPS------DILLTDRVAVVTGAG-AGIGRGIAAGLAAFGARVA
Mflv_2424|M.gilvum_PYR-GCK ---MAITAS------DILLTGRVAVVTGGG-AGIGRGIAQGLAAFGASVA
Mvan_4228|M.vanbaalenii_PYR-1 ---MTIAPS------DILLTGRVAVVTGGG-AGIGKGIAHGLAAFGASVA
MSMEG_4850|M.smegmatis_MC2_155 ---MAINPS------DILLTGRVAVVTGGG-AGIGRGIAEGLAAFGARVA
TH_3505|M.thermoresistible__bu ---LTIAPA------DILLTDRVAVVTGGG-AGLGRGIAAGFAAFGARVA
MAB_0833|M.abscessus_ATCC_1997 -MNRETFSR------LFDLTGRTAIVTGGT-RGIGRALAEGYACAGANVV
Rv3559c|M.tuberculosis_H37Rv -MNLSVAPKEIAG--HGLLDGKVVVVTAAAGTGIGSATARRALAEGADVV
: ::*.. *:* . . . * :.
Mb1385|M.bovis_AF2122/97 LGDVNLEATEVAAKRLGG--DDVALAVRCDVTQADDVDILIRTAVERFGG
MLBr_01807|M.leprae_Br4923 VTHR---ASVVPDWFFG---------VECDVTDNDAIGAAFKAVEEHQGP
MMAR_4756|M.marinum_M IWERDPQTCAQAAAELG------GLGIATDVRSGDQVDAALQRTQAELGE
MUL_0327|M.ulcerans_Agy99 IWERDPQTCAQAAAELG------GLGIATDVRSGDQVDAALQRTQAELGA
MAV_0894|M.avium_104 IWERDAQTCTRAAESIG------GLGIVTDVRDSGQVDTALQRTITELGT
Mflv_2424|M.gilvum_PYR-GCK IWERDPDTCAAAAAAIG------GLGLEVDVRDAAAVDTALDRTERELGT
Mvan_4228|M.vanbaalenii_PYR-1 IWERDPQTCGEAAASVG------ALGLPTDVRDAEAVQAALERTERELGT
MSMEG_4850|M.smegmatis_MC2_155 IWERDPETCEAAARAVG------GVGIVTDVRDADQVDAALAQTTSELGT
TH_3505|M.thermoresistible__bu IWERDPDSCARTAEEIG------ALGIVTDVRDSAAVSAALRQTTEQLGS
MAB_0833|M.abscessus_ATCC_1997 VASRKPEACTEAVERLRSL-GARALGVPTHTGDIHSLEELVRATAEEFGG
Rv3559c|M.tuberculosis_H37Rv ISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGR
: . . : .. . : . . . *
Mb1385|M.bovis_AF2122/97 LDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRER-
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ-
MMAR_4756|M.marinum_M VTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAE
MUL_0327|M.ulcerans_Agy99 VTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAG
MAV_0894|M.avium_104 PTILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVG
Mflv_2424|M.gilvum_PYR-GCK VSILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAAE
Mvan_4228|M.vanbaalenii_PYR-1 VSILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVG
MSMEG_4850|M.smegmatis_MC2_155 VSILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAE
TH_3505|M.thermoresistible__bu PTILVNNAGGTFSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAG
MAB_0833|M.abscessus_ATCC_1997 IDIVVNNAANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVAS-
Rv3559c|M.tuberculosis_H37Rv LDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAP
::* *.. : : . :: * .: :
Mb1385|M.bovis_AF2122/97 KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNA
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
MMAR_4756|M.marinum_M LPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNA
MUL_0327|M.ulcerans_Agy99 LPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNA
MAV_0894|M.avium_104 AGGSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNA
Mflv_2424|M.gilvum_PYR-GCK QTGSVINVTSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPYGIRVNG
Mvan_4228|M.vanbaalenii_PYR-1 QPGSVINITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNA
MSMEG_4850|M.smegmatis_MC2_155 MPGSIINLTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNA
TH_3505|M.thermoresistible__bu QPGSIVNITSIEGARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNA
MAB_0833|M.abscessus_ATCC_1997 PHAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNA
Rv3559c|M.tuberculosis_H37Rv HGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINA
. : *: . : *:*:*:.:: : : * . : *
Mb1385|M.bovis_AF2122/97 IAPGLIRSAMTEAMP-QRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLS
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMD-SKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
MMAR_4756|M.marinum_M IAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDIDEIASVAVFLASDMA
MUL_0327|M.ulcerans_Agy99 IAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDVDEIASVAVFLASDMA
MAV_0894|M.avium_104 IAPDITLTEGLQQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMS
Mflv_2424|M.gilvum_PYR-GCK LAPDLTMTEGLQKLAFGELSGTVARMVPMRRAGHVDEMASAAVFLASDMA
Mvan_4228|M.vanbaalenii_PYR-1 LAPDLTMTEGLQKLAFGDLSGTMADMVPMRRVGHVDEMASAAVFLASDMA
MSMEG_4850|M.smegmatis_MC2_155 LAPDLTVTDGLLALSGGRQPG--GDAIPMKRPGHVDEMAGAAVFLASGMS
TH_3505|M.thermoresistible__bu IAPDIAVTEGLQRMSPDGIPPEVGHAIPLGRPGHVDEIAGAAVFLASEMS
MAB_0833|M.abscessus_ATCC_1997 LAPGAIDTD-MVRKTPPAEVERMANTNHLKRLGLPDEMVGTALLLTSDAG
Rv3559c|M.tuberculosis_H37Rv VSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIAFLASDYS
::*. : * . *:... :*:* .
Mb1385|M.bovis_AF2122/97 SYMTGTVLDVTGGRFI---------------------
MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH-------------------
MMAR_4756|M.marinum_M RYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MUL_0327|M.ulcerans_Agy99 RYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MAV_0894|M.avium_104 GYLTGQTLHVDGGTQASSGWYHDPRTGDYRLGPAG--
Mflv_2424|M.gilvum_PYR-GCK SYITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA---
Mvan_4228|M.vanbaalenii_PYR-1 AYITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA---
MSMEG_4850|M.smegmatis_MC2_155 SYITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG---
TH_3505|M.thermoresistible__bu SYITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR
MAB_0833|M.abscessus_ATCC_1997 SYITGQTIIADGGLVAR--------------------
Rv3559c|M.tuberculosis_H37Rv SYLTGEVISVSCQHP----------------------
*::* .: .