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M. thermoresistible (build 8) TH_3122 (-)

annotation: short chain dehydrogenase
coordinates: 941682 - 942401
length: 240

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3122--100% (240)short chain dehydrogenase
M. thermoresistible (build 8)TH_3898-2e-2431.40% (242) PUTATIVE short chain dehydrogenase
M. thermoresistible (build 8)TH_2623-1e-2230.24% (248) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0950c-1e-2028.51% (242) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1235-9e-2229.88% (241) short chain dehydrogenase
M. tuberculosis H37RvRv0927c-1e-2028.51% (242) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG19e-1224.79% (238) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4657c-1e-7153.88% (245) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4581-8e-2229.34% (242) short-chain type dehydrogenase/reductase
M. avium 104MAV_1046-3e-2129.22% (243) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_4330-1e-11279.92% (239) short chain dehydrogenase
M. ulcerans Agy99MUL_4442-1e-2028.51% (242) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5843-3e-2633.47% (245) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3122|M.thermoresistible__bu      --------------VAAGAKNLGGLISTTLAERGVN-VAVHYHSAATEPD
MSMEG_4330|M.smegmatis_MC2_155      ----MSKLEGKSAVVAAGAKNLGGLISTTLASRGVN-VAVHYNSASTEAD
MAB_4657c|M.abscessus_ATCC_199      --MTDHSLNGKTVLITGGGKNLGGLIARDLAANGAGAIAIHYNSPSSKDA
Mvan_5843|M.vanbaalenii_PYR-1       --MSTAPLAGKRALVTGGSRGIGAEIVRRLAADGAA---VAFTYAASAAH
MMAR_4581|M.marinum_M               MILDRFRLDDQVAVITGGGRGLGAAIALAFAEAGAD----VVIASRTQSQ
MUL_4442|M.ulcerans_Agy99           MILDRFRLDDQVAVITGGGRGFGAAIALAFAEAGAD----VVIASRTQSQ
MAV_1046|M.avium_104                MILDRFRLDDKVAVITGAGRGLGAAIAVAFAEAGAD----VLIASRTESQ
Mb0950c|M.bovis_AF2122/97           MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGAD----VLIASRTSSE
Rv0927c|M.tuberculosis_H37Rv        MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGAD----VLIASRTSSE
Mflv_1235|M.gilvum_PYR-GCK          ---MFTSLQGRSAAVTGGSKGIGRGIAETFARAGIN----VVITARTQDD
MLBr_01807|M.leprae_Br4923          --MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIG--LAVARRLVADGH
                                                    .    ..  *    .  *            :   

TH_3122|M.thermoresistible__bu      ADKTVAAVEATGARAIKVQGDLTVPANVTRLFDATVEAFGGVDIAVNTVG
MSMEG_4330|M.smegmatis_MC2_155      ADKTVAAVQDAGVKAVKVQGDLTVPANVEKLFDTAIDAFGGVDIAINTVG
MAB_4657c|M.abscessus_ATCC_199      AEETVAAVQAAGAKAVAFQGDLTTGDAVSKLFADTVAAVGRPDIAINTVG
Mvan_5843|M.vanbaalenii_PYR-1       AEKVVAEVAASGGEAVAIRADSADPTQVADAVEQTVAELGGLDILVNNSA
MMAR_4581|M.marinum_M               LDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLDIVVNNVG
MUL_4442|M.ulcerans_Agy99           LDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLDIVVNNVG
MAV_1046|M.avium_104                LEAVAEQVRAAGRRAHVVAADLAHPESTAELAGRAVEAFGKLDIVVNNVG
Mb0950c|M.bovis_AF2122/97           LDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLDIVVNNVG
Rv0927c|M.tuberculosis_H37Rv        LDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLDIVVNNVG
Mflv_1235|M.gilvum_PYR-GCK          IDATVADLAGLAGTVTGVAADVTSPEDCRRVVETAIERHGGLDIVCPNAG
MLBr_01807|M.leprae_Br4923          RVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAG
                                       ..            .  * :           .    *  ::   . .

TH_3122|M.thermoresistible__bu      RVLRKPIVETTEAEYDAMFDINAKAAYFFLQEAGKRLNDG--GSVVTILT
MSMEG_4330|M.smegmatis_MC2_155      KVLRKPIAETTEAEYDSMFDINSKAAYFFLQQAGKRLNDN--GSITTIVT
MAB_4657c|M.abscessus_ATCC_199      KVIKKPFTEITEEEYDSASAVNAKSAFLFLKEAGKHVNDN--GKIVTLVT
Mvan_5843|M.vanbaalenii_PYR-1       VAHIAPIDDFPAEEFDRLVAINIGGVYWAVRSAIRYLSEG--ARIINIGS
MMAR_4581|M.marinum_M               GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGSIINIT
MUL_4442|M.ulcerans_Agy99           GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGGIINIT
MAV_1046|M.avium_104                GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGNIINIT
Mb0950c|M.bovis_AF2122/97           GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVINIS
Rv0927c|M.tuberculosis_H37Rv        GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVINIS
Mflv_1235|M.gilvum_PYR-GCK          IFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDALTASGHGRVIITSS
MLBr_01807|M.leprae_Br4923          ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGS
                                          :   .  :      .*   .      *   :     .      :

TH_3122|M.thermoresistible__bu      ALLAAFT-DGYSTYAGAKSPVEHFTRAAAKEFAPRQISVNNVAPGPMDTP
MSMEG_4330|M.smegmatis_MC2_155      SLLAAYT-DGYSTYAGSKSPVEHFTRAASKEFGVRGINVNNIAPGPMDTP
MAB_4657c|M.abscessus_ATCC_199      SLLGAYT-PFYAAYAGTKAPVEHFTRAASKEYGERGISVTAVGPGPMDTP
Mvan_5843|M.vanbaalenii_PYR-1       INADRIPGPGLSVYGMTKGAVSSFTRGLARDLGPRGITVNNVQPGPIDTD
MMAR_4581|M.marinum_M               STMGRVAGRGFAAYGTAKAALAHYTRLAALDLCPR-IRVNAIAPGSILTS
MUL_4442|M.ulcerans_Agy99           STMGRVAGRGFAAYGTAKVALAHYTRLAALDLCPR-IRVNAIAPGSILTS
MAV_1046|M.avium_104                STMGRLAGRGFAAYGTAKAALSHYTRLTALDLCPR-IRVNAIAPGSILTS
Mb0950c|M.bovis_AF2122/97           STMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSILTS
Rv0927c|M.tuberculosis_H37Rv        STMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSILTS
Mflv_1235|M.gilvum_PYR-GCK          ITGPITGFPGWSHYGASKAAQLGFLRTAAIELAPKKITVNAVLPGNILTE
MLBr_01807|M.leprae_Br4923          VVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTE
                                               : *. :*       *  : :   : : .. : ** : * 

TH_3122|M.thermoresistible__bu      FFYGQETPERVTFHKSQGLGN-----RLTRIEDIAPLVAFLTD-EGHWIT
MSMEG_4330|M.smegmatis_MC2_155      FFYPEETPERVEFHKSQAMGN-----RLTDIGDIAPLAVFLAD-EGHWIN
MAB_4657c|M.abscessus_ATCC_199      FFYPAEGEDAVAYHKTAAALSPFSKTGLTDIEDIAPFIRFLVS-DGWWIT
Mvan_5843|M.vanbaalenii_PYR-1       AN-PDDGAFAESLKQVVAQGR------YGHTSDVASLVSFLAGPESGYIT
MMAR_4581|M.marinum_M               ALEVVAANDELRAPMEQATPLR----RLGDPVDIAAAAVYLASPAGSFLT
MUL_4442|M.ulcerans_Agy99           ALEVVAANDELRAPMEQATPLR----RLGDPVDIAAAAVYLASPAGSFLT
MAV_1046|M.avium_104                ALDVVASNDELRAPMEKATPLR----RLGDPVDIASAAVYLASPAGEFLT
Mb0950c|M.bovis_AF2122/97           ALEVVAANDELRAPMEQATPLR----RLGDPVDIAAAAVYLASPAGSFLT
Rv0927c|M.tuberculosis_H37Rv        ALEVVAANDELRAPMEQATPLR----RLGDPVDIAAAAVYLASPAGSFLT
Mflv_1235|M.gilvum_PYR-GCK          GLVEMGQSYIDQMAAAVPAGK------LGEVADIGNAALFFATDEAAYIT
MLBr_01807|M.leprae_Br4923          MTRAMDSKYQEAALQAIPLGR------IGAVEEIAGAVSFLASEDAGYIS
                                                                    ::.    ::.   . ::.

TH_3122|M.thermoresistible__bu      GQTIFANGGYTTR---------
MSMEG_4330|M.smegmatis_MC2_155      GQTLFTNGGYTTR---------
MAB_4657c|M.abscessus_ATCC_199      GQTILINGGYTTK---------
Mvan_5843|M.vanbaalenii_PYR-1       GAHLNVDGGFTV----------
MMAR_4581|M.marinum_M               GKTLEVDGGLTHPNLDIPVPDL
MUL_4442|M.ulcerans_Agy99           GKTLEVDGGLTHPNLDIPVPDL
MAV_1046|M.avium_104                GKTLEVDGGLTYPNLDIPVPDL
Mb0950c|M.bovis_AF2122/97           GKTLEVDGGLTFPNLDLPIPDL
Rv0927c|M.tuberculosis_H37Rv        GKTLEVDGGLTFPNLDLPIPDL
Mflv_1235|M.gilvum_PYR-GCK          GQSLVVDGGQILPESPEALADL
MLBr_01807|M.leprae_Br4923          GAVIPVDGGLGMGH--------
                                    *  :  :**