For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSPLKSRRAFVTGGSRGIGAGIVRRLAEDGARVVFTYSSSVQQAADVVDDINEDGGWARAVKADVADPD QLGAAIGQAAEELGGLDILVNNAGILSIGDVDTATLADFDEIVAVNVRAVFAGIKAASPHLTEGGRIVTI GSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPRGITINNVQPGPIGTDMNPEDGQLADILRPNIAV GRYGQPRDIASLVSYLVSDEAWYITGTAINIDGGFTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0827 | - | - | 100% (247) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0952 | - | 2e-32 | 35.92% (245) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2723c | - | 1e-31 | 34.58% (240) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2025 | fabG3 | 1e-38 | 39.76% (254) | 20-beta-hydroxysteroid dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4505 | - | 9e-41 | 40.94% (254) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2002 | fabG3 | 1e-38 | 39.76% (254) | 20-beta-hydroxysteroid dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-34 | 38.17% (241) | 3-oxoacyl- |
| M. marinum M | MMAR_2981 | fabG3_1 | 4e-41 | 40.47% (257) | 20-beta-hydroxysteroid dehydrogenase FabG3_1 |
| M. avium 104 | MAV_2509 | - | 3e-39 | 39.53% (253) | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4351 | - | 1e-76 | 56.50% (246) | oxidoreductase YjgI |
| M. thermoresistible (build 8) | TH_3969 | - | 1e-34 | 34.57% (243) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 9e-34 | 40.25% (241) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_5843 | - | 3e-74 | 55.10% (245) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4351|M.smegmatis_MC2_155 ------------------------MTQAGSSTPLADRRVLVTGGSRGIGA
Mvan_5843|M.vanbaalenii_PYR-1 ----------------------------MSTAPLAGKRALVTGGSRGIGA
MAB_0827|M.abscessus_ATCC_1997 -----------------------------MTSPLKSRRAFVTGGSRGIGA
Mb2025|M.bovis_AF2122/97 -----------------------------MSGRLIGKVALVSGGARGMGA
Rv2002|M.tuberculosis_H37Rv -----------------------------MSGRLIGKVALVSGGARGMGA
MMAR_2981|M.marinum_M -----------------------------MAGRLTGKVALVSGGARGMGA
MAV_2509|M.avium_104 -----------------------------MAERLAGKVALVSGGARGMGA
Mflv_4505|M.gilvum_PYR-GCK -----------------------------MTGRLAGKVALISGAARGMGA
TH_3969|M.thermoresistible__bu MGFPEQQQQVPGRQSAMDPVPDCGESSYRGSGKLTGKRAVITGGDSGIGR
MLBr_01807|M.leprae_Br4923 ---------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGL
MUL_0315|M.ulcerans_Agy99 ------------------------MRPD-SSPSWCTITSVVTGGASGIGL
.::*. *:*
MSMEG_4351|M.smegmatis_MC2_155 GIVRRLAADGAAVAFTYGASAAEAEKLVGDLTSEGAKVTAIQADSADPDQ
Mvan_5843|M.vanbaalenii_PYR-1 EIVRRLAADGAAVAFTYAASAAHAEKVVAEVAASGGEAVAIRADSADPTQ
MAB_0827|M.abscessus_ATCC_1997 GIVRRLAEDGARVVFTYSSSVQQAADVVDDINEDGGWARAVKADVADPDQ
Mb2025|M.bovis_AF2122/97 SHVRAMVAEGAKVVFGDILDEEGKAVAAELADAAR----YVHLDVTQPAQ
Rv2002|M.tuberculosis_H37Rv SHVRAMVAEGAKVVFGDILDEEGKAVAAELADAAR----YVHLDVTQPAQ
MMAR_2981|M.marinum_M SHVRALVAEGAHVVLGDILDDEGRAVAAELGDAAR----YVHLDVTQPEQ
MAV_2509|M.avium_104 SHVRSLVAEGAKVVFGDILDDEGKAVAAEVGEATR----YLHLDVTKPED
Mflv_4505|M.gilvum_PYR-GCK SHARVMAGHGAKVVCGDILDSDGEAVAAELGDAAR----YVHLDVTSPDD
TH_3969|M.thermoresistible__bu AVAIAYAREGADVLVSYLNEDDDAAEVAQLVTDAGRRCVLVPGDLSDPAH
MLBr_01807|M.leprae_Br4923 AVARRLVADGHRVAVTHRASVVPDWFFG------------VECDVTDNDA
MUL_0315|M.ulcerans_Agy99 AIARRLSADGTDVATLDLK--TPDGGLA------------FSADVTNRSQ
. .* * . * :.
MSMEG_4351|M.smegmatis_MC2_155 VAAAVSQAVADLGGLDVLVN-NAGVAHVAPAEEFTREQFDRLVNVNIGGV
Mvan_5843|M.vanbaalenii_PYR-1 VADAVEQTVAELGGLDILVN-NSAVAHIAPIDDFPAEEFDRLVAINIGGV
MAB_0827|M.abscessus_ATCC_1997 LGAAIGQAAEELGGLDILVN-NAGILSIGDVDTATLADFDEIVAVNVRAV
Mb2025|M.bovis_AF2122/97 WTAAVDTAVTAFGGLHVLVN-NAGILNIGTIEDYALTEWQRILDVNLTGV
Rv2002|M.tuberculosis_H37Rv WTAAVDTAVTAFGGLHVLVN-NAGILNIGTIEDYALTEWQRILDVNLTGV
MMAR_2981|M.marinum_M WTAAVDTAVNEFGGLHVLVN-NAGILNIGTIEDYALSEWQRILDINVTGV
MAV_2509|M.avium_104 WDAAVATALAEFGRIDVLVN-NAGIINIGTLEDYALSEWQRILDINLTGV
Mflv_4505|M.gilvum_PYR-GCK WDRAVAAAVADFGGLDVLVN-NAGILNIGTVEDYELSEWHRILDVNLTGV
TH_3969|M.thermoresistible__bu CRSVIDRAVSEFDGLDVLVVNHAHQMTHPTLEEISDEEWDYTFRLNIGAY
MLBr_01807|M.leprae_Br4923 IGAAFKAVEEHQGPVEVLVA-NAGITSDMLIMRMSEEQFQKVIDVNLTGV
MUL_0315|M.ulcerans_Agy99 VDAALAAIRQRLGPVTILVN-AAGLDGFKRFSNITFEDWQRVIDVNLNGV
.. . : :** : ::. . :*: .
MSMEG_4351|M.smegmatis_MC2_155 FWAIHAAIPHFGEG--SRIINIGSINADRVPAPNLGVYAMTKGAVQALTI
Mvan_5843|M.vanbaalenii_PYR-1 YWAVRSAIRYLSEG--ARIINIGSINADRIPGPGLSVYGMTKGAVSSFTR
MAB_0827|M.abscessus_ATCC_1997 FAGIKAASPHLTEG--GRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTR
Mb2025|M.bovis_AF2122/97 FLGIRAVVKPMKEAGRGSIINISSIEG-LAGTVACHGYTATKFAVRGLTK
Rv2002|M.tuberculosis_H37Rv FLGIRAVVKPMKEAGRGSIINISSIEG-LAGTVACHGYTATKFAVRGLTK
MMAR_2981|M.marinum_M FLGIRAAVKPMKEAGRGSIINISSIEG-LAGTIASHGYTVSKFAVRGLTK
MAV_2509|M.avium_104 FLGIRAVVKPMKKAGRGSIINISSIEG-MAGTIACHGYTATKFAVRGLTK
Mflv_4505|M.gilvum_PYR-GCK FLGIRAATPTMKAAGRGSIINIASIEG-MAGTVGCHGYTATKFAVRGLTK
TH_3969|M.thermoresistible__bu FHLVKAALPHLKPG--ASIIGSSSVNS-DMPSPTLAPYAATKAAIANFSA
MLBr_01807|M.leprae_Br4923 FRVAKLASRNMIKQRFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMAR
MUL_0315|M.ulcerans_Agy99 FHTIQAVLPDMVAAGWGRIVNISSSST-HSGTPYMTHYVAAKSAVNGLTK
: : . : . : .* * :* .: ::
MSMEG_4351|M.smegmatis_MC2_155 GLARELGPRGITITNVQPGPIDTDMNPAD--G---GLAEVMTSVTALGRY
Mvan_5843|M.vanbaalenii_PYR-1 GLARDLGPRGITVNNVQPGPIDTDANPDD--G---AFAESLKQVVAQGRY
MAB_0827|M.abscessus_ATCC_1997 GLAREFGPRGITINNVQPGPIGTDMNPED--G---QLADILRPNIAVGRY
Mb2025|M.bovis_AF2122/97 STALELGPSGIRVNSIHPGLVKTPMT---------DWVPEDIFQTALGRA
Rv2002|M.tuberculosis_H37Rv STALELGPSGIRVNSIHPGLVKTPMT---------DWVPEDIFQTALGRA
MMAR_2981|M.marinum_M STALELGPSGIRVNSIHPGLVKTPMT---------EWVPEDLFQTALGRA
MAV_2509|M.avium_104 SAALELGPSGIRVNSIHPGLIKTPMT---------EWVPEDIFQSALGRA
Mflv_4505|M.gilvum_PYR-GCK STALELGPFGIRVNSVHPGLVKTPMA---------DWVPEDIFQSALGRI
TH_3969|M.thermoresistible__bu SLAQMLGDKGIRVNSVAPGPIWTPLIPSTMPP---EKVARFGDDTPLGRA
MLBr_01807|M.leprae_Br4923 SLARELGSRSITANVVAPGFIDTEMTRAMDSK----YQEAALQAIPLGRI
MUL_0315|M.ulcerans_Agy99 ALALEYGPSGITVNAVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRI
. * * .* . : ** : * . *
MSMEG_4351|M.smegmatis_MC2_155 GHAGDIAAVVSFLAGPESGYVTGASWNVDGGYTA----------------
Mvan_5843|M.vanbaalenii_PYR-1 GHTSDVASLVSFLAGPESGYITGAHLNVDGGFTV----------------
MAB_0827|M.abscessus_ATCC_1997 GQPRDIASLVSYLVSDEAWYITGTAINIDGGFTA----------------
Mb2025|M.bovis_AF2122/97 AEPVEVSNLVVYLASDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQP
Rv2002|M.tuberculosis_H37Rv AEPVEVSNLVVYLASDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQP
MMAR_2981|M.marinum_M AEPMEVSNLVVYLASDESSYSTGAEFVVDGGTVAGLAHKDFSAVDVAAQP
MAV_2509|M.avium_104 AEPKEVSNLVVYLASDESSYSTGSEFVVDGGTTAGLGHKDFSNVETDAQP
Mflv_4505|M.gilvum_PYR-GCK AQPHEVSNLVVYLASDESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQP
TH_3969|M.thermoresistible__bu GQPAELAGAYVLLAADEGSYISGARIAVTGGRPIL---------------
MLBr_01807|M.leprae_Br4923 GAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH--------------
MUL_0315|M.ulcerans_Agy99 GKPEDIAAACAFLVSEEAGYITGQILGVNGGRNT----------------
. ::: *.. :. * :* : **
MSMEG_4351|M.smegmatis_MC2_155 ----
Mvan_5843|M.vanbaalenii_PYR-1 ----
MAB_0827|M.abscessus_ATCC_1997 ----
Mb2025|M.bovis_AF2122/97 EWVT
Rv2002|M.tuberculosis_H37Rv EWVT
MMAR_2981|M.marinum_M EWVT
MAV_2509|M.avium_104 DWVT
Mflv_4505|M.gilvum_PYR-GCK EWIT
TH_3969|M.thermoresistible__bu ----
MLBr_01807|M.leprae_Br4923 ----
MUL_0315|M.ulcerans_Agy99 ----