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MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEAGHALVLRADE VIAAVDRADEEMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIRPSDEDVTYGEAPGLLTEYDL VITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAACDSVTPAELADETWISVPEGFPVDDVLVSLG VSTGIIPRVRFRFKDFQIVEDMVAHGHGVALMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAI AATIQGLRDAAAVLESR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0678 | - | - | 100% (297) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 1e-14 | 30.52% (249) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2680c | - | 5e-14 | 26.27% (255) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 2e-05 | 26.03% (146) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 9e-20 | 30.83% (253) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-05 | 26.03% (146) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 6e-06 | 20.99% (243) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4902 | - | 3e-23 | 30.43% (322) | putative regulatory protein |
| M. avium 104 | MAV_0094 | - | 2e-09 | 31.40% (121) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3260 | - | 1e-22 | 33.20% (250) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-09 | 25.91% (193) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3983 | - | 8e-22 | 31.47% (286) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 2e-21 | 30.46% (302) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2303c|M.bovis_AF2122/97 ---MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASME
Rv2282c|M.tuberculosis_H37Rv ---MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASME
MSMEG_3260|M.smegmatis_MC2_155 -----MDTRR-----LRLLLALSRLGSMRAVADAFSLTTSTVSQQLAALA
Mvan_3401|M.vanbaalenii_PYR-1 -----MDTRR-----LELLLALSRLGSMRAVADAHHLTTSTVSQQIAALA
MAB_0678|M.abscessus_ATCC_1997 -----MDVRR-----LRILREFADRGTVGEVADAMSLTPSAVSQQLKVLT
MUL_3983|M.ulcerans_Agy99 ----MLNLQR-----VVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLE
MMAR_4902|M.marinum_M ----MIDPHR-----LRILRAVVAEGSIGGAAAALGCTPSAVSQHIAVLQ
Mflv_1346|M.gilvum_PYR-GCK -----MKLRH-----LRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLE
TH_3504|M.thermoresistible__bu VPSPKIDLRR-----LAQFVAVAELGSFTRAAATLHLSQQALSSAVRALE
MLBr_02041|M.leprae_Br4923 ---MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALE
MAV_0094|M.avium_104 -MGQVLDIAP-----LRSLVAVADCGGFHRAAAALHLSQSAVSQHLRRIE
. . : . . .* .:* : :
Mb2303c|M.bovis_AF2122/97 AQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLG-SLRTEG
Rv2282c|M.tuberculosis_H37Rv AQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLG-SLRTEG
MSMEG_3260|M.smegmatis_MC2_155 KETDTQLIEPDGRRVRLTPAGRRLADHAVTILAAVDAARLDLDPDAEPAG
Mvan_3401|M.vanbaalenii_PYR-1 RDTGAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDPDAEPAG
MAB_0678|M.abscessus_ATCC_1997 REAGVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADEEMVAYREGTQ
MUL_3983|M.ulcerans_Agy99 RECGMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVA
MMAR_4902|M.marinum_M REIGLTLVEKVGRGIAPTDAGATLAAESAAVFDGLSRLDGLVADLRHGRA
Mflv_1346|M.gilvum_PYR-GCK REVGADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAE
TH_3504|M.thermoresistible__bu NDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQ
MLBr_02041|M.leprae_Br4923 SGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLR
MAV_0094|M.avium_104 AVVGEPIVQRSGRGVVFTEVGQKALRHARTILAAHDTALDDLG---ATEN
. : * * * :
Mb2303c|M.bovis_AF2122/97 -RQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILT-ATNSEHA
Rv2282c|M.tuberculosis_H37Rv -RQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILT-ATNSEHA
MSMEG_3260|M.smegmatis_MC2_155 -TLRVGGFATG-LRVSLLP------ILRELGRTHPSVEVEIS-EYEPLEA
Mvan_3401|M.vanbaalenii_PYR-1 -TVRVGGFATG-IRVSLLP------IVADLAVRYPEVDVVIS-EYEPVEA
MAB_0678|M.abscessus_ATCC_1997 PVVRVASFPSG--AGVLLP--------RVVAAVAEAVDIRPS-DEDVTYG
MUL_3983|M.ulcerans_Agy99 GRLRVAAFRTL--LLSLPPR-----VLDALARDYPDLRVEVA-QREADEA
MMAR_4902|M.marinum_M GTLRVSYFASA--GAAWMP-----AVIATISSEYPAVRLDLR-LVELADA
Mflv_1346|M.gilvum_PYR-GCK GRLVVGCVGSA--TYSLLPR-----LVRELRAALPAVDLRVRGEMLAPEQ
TH_3504|M.thermoresistible__bu AHYVIGHTPALSGAEAYAL-------IEPAVTAYPSTSFTLR-QLYPDAL
MLBr_02041|M.leprae_Br4923 GGMRLGLIPTV--APYVLPT-----MLTGLTHRLPTLTLRVV-EDQTEHL
MAV_0094|M.avium_104 KVLTIGATEHG--ADVMLAG-----LSGALRDRLPDLRVRFR-LDRNVSL
: .
Mb2303c|M.bovis_AF2122/97 IAAVRDGIADLGFIEN-----PCPPTGLGSVVVARDELVVVVPPG----H
Rv2282c|M.tuberculosis_H37Rv IAAVRDGIADLGFIEN-----PCPPTGLGSVVVARDELVVVVPPG----H
MSMEG_3260|M.smegmatis_MC2_155 FELLVDDDLDLALTYEYDLAPASPDPVLEAFPLWSTPWGLGVPSSEVTAG
Mvan_3401|M.vanbaalenii_PYR-1 FKLLTADDLDLALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSG----T
MAB_0678|M.abscessus_ATCC_1997 EAPGLLTEYDLVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAA
MUL_3983|M.ulcerans_Agy99 TSGLLAGTFDVVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIG--PW
MMAR_4902|M.marinum_M DDAAPDVEINVAGMPG------TELSNYDTAALVTEDYVVVVGAGDSLAE
Mflv_1346|M.gilvum_PYR-GCK LAALHAKDIDLALMRP-----PVDDPALTAVSLRRDRLLVALPAGHRCAD
TH_3504|M.thermoresistible__bu TDAVFDGTVQLGLRRG-----VVPTPELATAVIGYHRVRVAFVDSHPLAA
MLBr_02041|M.leprae_Br4923 LTALREGALDAAMIALP-----VETAGIAEIPIYDEDFVLALPPGHPLSG
MAV_0094|M.avium_104 ADSIDRGLVDVAIMLDG-----AGLDRANASGLVRLQWVS----------
: :
Mb2303c|M.bovis_AF2122/97 KWARRSRVVSARELAQTPLVTR--EPNSGIRDSLTAALRDTLG-EDMQQA
Rv2282c|M.tuberculosis_H37Rv KWARRSRVVSARELAQTPLVTR--EPNSGIRDSLTAALRDTLG-EDMQQA
MSMEG_3260|M.smegmatis_MC2_155 TATADIRNYADRWWIVNSRNTA--DEDAVRTLASLAGFRPRIA-HQIDSL
Mvan_3401|M.vanbaalenii_PYR-1 AADRGLMTFADSTWIVNSRNTA--DETAVRTLASLAGFTPTIA-HQIDSL
MAB_0678|M.abscessus_ATCC_1997 CDSVTPAELADETWISVPEGFP--VDDVLVSLGVSTGIIPRVR-FRFKDF
MUL_3983|M.ulcerans_Agy99 SDATTLSDLEYASWALDPEPTV--PGRWARSVCRAAGFEPDVR-FDGVDL
MMAR_4902|M.marinum_M RDSVTLRELAGEPWIDNDVARGN-CRENLLRACTAAGFTPCFR-VETHDY
Mflv_1346|M.gilvum_PYR-GCK RDEVSLADLRDEDFISHAGGGRSRMSALLAALCADAGFSPRIR-DEVDET
TH_3504|M.thermoresistible__bu RESVDITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYV-VSRVQG
MLBr_02041|M.leprae_Br4923 KRRVPTTALAQLPLLLLDEGHC--LRDQTLDICRKSGVQAELANTRAASL
MAV_0094|M.avium_104 ARTLTIAPKDPLPLVIFSEPCT--LREPAFAILDSHRIDYEIA-AECGDL
. .
Mb2303c|M.bovis_AF2122/97 PPVLELSSAAA-VRAAVLAGAG-PAAMSRL--AIADDLAFGRLLAVDIPA
Rv2282c|M.tuberculosis_H37Rv PPVLELSSAAA-VRAAVLAGAG-PAAMSRL--AIADDLAFGRLLAVDIPA
MSMEG_3260|M.smegmatis_MC2_155 DLLEDLILEGFGVGLLPITRAV-RDGVTVM--PMSDPKVVLTAFAVVRRG
Mvan_3401|M.vanbaalenii_PYR-1 DLVEDLIVAGFGVGLLPLGRPT-SPGVTVL--PLQNPDVTLTAYAVTRRG
MAB_0678|M.abscessus_ATCC_1997 QIVEDMVAHGHGVALMPRYASR-SPRVARV--VIREVRAARLYEVLARPG
MUL_3983|M.ulcerans_Agy99 LVHLQMVQAGLAVAILPALLGQDRMRGVRL--APLPASPKRQLFTLTRTS
MMAR_4902|M.marinum_M VTAVRFVAAGVGLTVVPRLALIDLPAGVRT--VAISEPTPRRTIVVRRHH
Mflv_1346|M.gilvum_PYR-GCK STLVTLVAGGLGVALVPEPTAALEIGGVTY--RPLAAKAGATIELLAVYR
TH_3504|M.thermoresistible__bu AATVAAPLTTGGIAFVTAAAGPTMNGRVQV--VDLTPP-----LLVPVQA
MLBr_02041|M.leprae_Br4923 ATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRS
MAV_0094|M.avium_104 SGLYAAVRSGLGVALLPMIGKFPDGLGPAEG----LPPANNASILVRGRT
: :
Mb2303c|M.bovis_AF2122/97 LNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST------
Rv2282c|M.tuberculosis_H37Rv LNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST------
MSMEG_3260|M.smegmatis_MC2_155 RSTWPPLRLVLDRLR-PPDGRPVPLMSWPRP---TVHGSG
Mvan_3401|M.vanbaalenii_PYR-1 RSAWSPLRAILDRMR-PPAG-LLQHPTWPRPEAAVANQSA
MAB_0678|M.abscessus_ATCC_1997 ARHRPAIAATIQGLR--DAAAVLESR--------------
MUL_3983|M.ulcerans_Agy99 RTAHPAVVAFRTALAEGFDAQHQYD---------------
MMAR_4902|M.marinum_M RARNNVVAGRVLELIHQQAVRTHGPAVGALA---------
Mflv_1346|M.gilvum_PYR-GCK SADASPLTAKVVDVLRATV---------------------
TH_3504|M.thermoresistible__bu LWQRHTLSAIRDRILEGLG---------------------
MLBr_02041|M.leprae_Br4923 ASGRSASYRQIAKIIGELISTEHHVRLVA-----------
MAV_0094|M.avium_104 GIDPALLSTVDTAVRDLLATAT------------------