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MDTRRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDTGAALIEPEGRRVRLTPAGKRLADHAVT ILAAVDRARLDLDPDAEPAGTVRVGGFATGIRVSLLPIVADLAVRYPEVDVVISEYEPVEAFKLLTADDL DLALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSGTAADRGLMTFADSTWIVNSRNTADETAVRTLASL AGFTPTIAHQIDSLDLVEDLIVAGFGVGLLPLGRPTSPGVTVLPLQNPDVTLTAYAVTRRGRSAWSPLRA ILDRMRPPAGLLQHPTWPRPEAAVANQSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | - | 100% (309) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 2e-10 | 26.80% (250) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4031 | - | 1e-07 | 29.10% (189) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 4e-07 | 25.00% (144) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 1e-15 | 31.58% (304) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 4e-07 | 25.00% (144) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-07 | 26.16% (172) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0678 | - | 2e-21 | 30.26% (304) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4117 | - | 2e-28 | 35.34% (283) | putative regulatory protein |
| M. avium 104 | MAV_1538 | - | 4e-14 | 24.32% (259) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3260 | - | 1e-118 | 71.48% (305) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-08 | 39.19% (74) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3983 | - | 1e-27 | 34.98% (283) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3401|M.vanbaalenii_PYR-1 -------MDTRRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDT
MSMEG_3260|M.smegmatis_MC2_155 -------MDTRRLRLLLALSRLGSMRAVADAFSLTTSTVSQQLAALAKET
MMAR_4117|M.marinum_M ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
MUL_3983|M.ulcerans_Agy99 ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
Mb0384|M.bovis_AF2122/97 -------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
Rv0377|M.tuberculosis_H37Rv -------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
MAB_0678|M.abscessus_ATCC_1997 -------MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREA
Mflv_1346|M.gilvum_PYR-GCK -------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLEREV
MAV_1538|M.avium_104 -------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
. . .* :: : *
Mvan_3401|M.vanbaalenii_PYR-1 GAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDP-DAEPAGTV
MSMEG_3260|M.smegmatis_MC2_155 DTQLIEPDGRRVRLTPAGRRLADHAVTILAAVDAARLDLDP-DAEPAGTL
MMAR_4117|M.marinum_M GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
MUL_3983|M.ulcerans_Agy99 GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
Mb0384|M.bovis_AF2122/97 DDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRR-LL
Rv0377|M.tuberculosis_H37Rv DDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRR-LL
MAB_0678|M.abscessus_ATCC_1997 GVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADEEMVAYREGTQPVV
Mflv_1346|M.gilvum_PYR-GCK GADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAEGRL
MAV_1538|M.avium_104 GVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEI
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
. *: : .. * : .
Mvan_3401|M.vanbaalenii_PYR-1 RVGGFATGIRVSLLPIVADLAVRYPEVDVVIS-EYEPVEAFKLLTADDLD
MSMEG_3260|M.smegmatis_MC2_155 RVGGFATGLRVSLLPILRELGRTHPSVEVEIS-EYEPLEAFELLVDDDLD
MMAR_4117|M.marinum_M RVAAFQTLLLSLLPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
MUL_3983|M.ulcerans_Agy99 RVAAFRTLLLSLPPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
Mb0384|M.bovis_AF2122/97 RIAASSAFAEHAAPGLIELFSSRADDLSVELS-VHPTSRFRELICSRAVD
Rv0377|M.tuberculosis_H37Rv RIAASSAFAEHAAPGLIELFSSRADDLSVELS-VHPTSRFRELICSRAVD
MAB_0678|M.abscessus_ATCC_1997 RVASFPSGAGVLLPRVVAAVA---EAVDIRPS-DEDVTYGEAPGLLTEYD
Mflv_1346|M.gilvum_PYR-GCK VVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQLAALHAKDID
MAV_1538|M.avium_104 RLAYLSSFGSTVVPRLIARFKESSPRVTFTLE-EGAAESIADRVRSGGVD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVV-EDQTEHLLTALREGALD
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYPSTSFTLR-QLYPDALTDAVFDGTVQ
:. : :: . :
Mvan_3401|M.vanbaalenii_PYR-1 LALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSG----TAADRGLMTFA
MSMEG_3260|M.smegmatis_MC2_155 LALTYEYDLAPASPDPVLEAFPLWSTPWGLGVPSSEVTAGTATADIRNYA
MMAR_4117|M.marinum_M VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIG--PWSDATTLSDLE
MUL_3983|M.ulcerans_Agy99 VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIG--PWSDATTLSDLE
Mb0384|M.bovis_AF2122/97 IAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSP--LAAGIPMPALLR
Rv0377|M.tuberculosis_H37Rv IAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSP--LAAGIPMPALLR
MAB_0678|M.abscessus_ATCC_1997 LVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAACDSVTPAELA
Mflv_1346|M.gilvum_PYR-GCK LALMR-----PPVDDPALTAVSLRRDRLLVALPAGHRCADRDEVSLADLR
MAV_1538|M.avium_104 IGVVS-----PRPVERTLAWRSLFRQRLGVAVPDGHRFARGAAVSMVDLA
MLBr_02041|M.leprae_Br4923 AAMIA-----LPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALA
TH_3504|M.thermoresistible__bu LGLRR-----GVVPTPELATAVIGYHRVRVAFVDSHPLAARESVDITELA
: . : :
Mvan_3401|M.vanbaalenii_PYR-1 DSTWIVNSRN--TADETAVRTLASLAGFTPTIA-HQIDSLDLVEDLIVAG
MSMEG_3260|M.smegmatis_MC2_155 DRWWIVNSRN--TADEDAVRTLASLAGFRPRIA-HQIDSLDLLEDLILEG
MMAR_4117|M.marinum_M YASWALDPEP--TVPGRWARSVCRAAGFEPDVR-FDGVDLLVHLQMVQAG
MUL_3983|M.ulcerans_Agy99 YASWALDPEP--TVPGRWARSVCRAAGFEPDVR-FDGVDLLVHLQMVQAG
Mb0384|M.bovis_AF2122/97 HQQWMLGPSAG-SVDGEIATMLRGLAIPESQQR-IFQSDAAALEEVMRVG
Rv0377|M.tuberculosis_H37Rv HQQWMLGPSAG-SVDGEIATMLRGLAIPESQQR-IFQSDAAALEEVMRVG
MAB_0678|M.abscessus_ATCC_1997 DETWISVPEG--FPVDDVLVSLGVSTGIIPRVR-FRFKDFQIVEDMVAHG
Mflv_1346|M.gilvum_PYR-GCK DEDFISHAGGGRSRMSALLAALCADAGFSPRIR-DEVDETSTLVTLVAGG
MAV_1538|M.avium_104 DEPFVTMHPG--FGMRRLLDELCAAAQFRPRVA-LQAPNLTTAASLVAAG
MLBr_02041|M.leprae_Br4923 QLPLLLLDEG--HCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGG
TH_3504|M.thermoresistible__bu REQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATVAAPLTTG
: . : *
Mvan_3401|M.vanbaalenii_PYR-1 FGVGLLP----LGRPTSPGVTVLPLQNPDVTLTAYAVTRRGRSAWSPLRA
MSMEG_3260|M.smegmatis_MC2_155 FGVGLLP----ITRAVRDGVTVMPMSDPKVVLTAFAVVRRGRSTWPPLRL
MMAR_4117|M.marinum_M LAVAILPA--LLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAVVA
MUL_3983|M.ulcerans_Agy99 LAVAILPA--LLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAVVA
Mb0384|M.bovis_AF2122/97 GATLAIGF--AVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVS
Rv0377|M.tuberculosis_H37Rv GATLAIGF--AVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVS
MAB_0678|M.abscessus_ATCC_1997 HGVALMPR--YASRS--PRVARVVIREVRAARLYEVLARPGARHRPAIAA
Mflv_1346|M.gilvum_PYR-GCK LGVALVPE--PTAALEIGGVTYRPLAAKAGATIELLAVYRSADASPLTAK
MAV_1538|M.avium_104 LGISLVP---IDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARD
MLBr_02041|M.leprae_Br4923 LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQ
TH_3504|M.thermoresistible__bu -GIAFVTA--AAGPTMNGRVQVVDLTPPLLVPVQALWQR--HTLSAIRDR
. :
Mvan_3401|M.vanbaalenii_PYR-1 ILDRMRPPAG-LLQHPTWPRPEAAVANQSA------
MSMEG_3260|M.smegmatis_MC2_155 VLDRLRPPDGRPVPLMSWPRP---TVHGSG------
MMAR_4117|M.marinum_M FRTALAEGFDAQHQYD--------------------
MUL_3983|M.ulcerans_Agy99 FRTALAEGFDAQHQYD--------------------
Mb0384|M.bovis_AF2122/97 ELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv ELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
MAB_0678|M.abscessus_ATCC_1997 TIQGLRDAAAVLESR---------------------
Mflv_1346|M.gilvum_PYR-GCK VVDVLRATV---------------------------
MAV_1538|M.avium_104 FIAGAAAVGHGGW-----------------------
MLBr_02041|M.leprae_Br4923 IAKIIGELISTEHHVRLVA-----------------
TH_3504|M.thermoresistible__bu ILEGLG------------------------------