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ELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEFGKALLPLAGAA LRTVGEIRSAADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVTVTLTEARSDQLATAVVERRLD MAVMAWLAQPPSQLRERILAKENIVAVVHRDDPLAGRESVALAELRDRALISHPQGCEIRTALDQACLAT GFTPRVVFETSSADMMRHLVVRDLGVAVTPRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAF AACIDELCRKDANLVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3208c | - | - | 100% (297) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 4e-56 | 44.32% (273) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0055c | - | 1e-28 | 33.20% (259) | DNA-binding transcriptional regulator CynR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 4e-17 | 31.71% (205) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_3565 | - | 4e-49 | 42.91% (275) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 4e-17 | 31.71% (205) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02041 | oxyR | 5e-18 | 28.62% (276) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 6e-21 | 29.88% (251) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_1538 | - | 8e-23 | 28.81% (243) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 7e-51 | 42.86% (273) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 7e-20 | 32.08% (265) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 8e-21 | 29.88% (251) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 3e-45 | 40.96% (271) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
MSMEG_3840|M.smegmatis_MC2_155 -------MELRQLEYFVAVAEEANFTRAAQRIHVAQPAVSASIRQLEREL
MAB_3208c|M.abscessus_ATCC_199 -------MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLEREL
MMAR_4157|M.marinum_M -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
MUL_4020|M.ulcerans_Agy99 -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
Mb0121|M.bovis_AF2122/97 -------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLEREL
Rv0117|M.tuberculosis_H37Rv -------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLEREL
MAV_1538|M.avium_104 -------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
. : ::.: . *: : * :: : ** :
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSV
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV
MSMEG_3840|M.smegmatis_MC2_155 GQPLFDRSRREVRLTAAGEAVLPHAHAALRSVAAARTAVAEVSGLVRGSV
MAB_3208c|M.abscessus_ATCC_199 GNELFDRSSRVLRLTEFGKALLPLAGAALRTVGEIRSAADAMAGVLCGQL
MMAR_4157|M.marinum_M GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
MUL_4020|M.ulcerans_Agy99 GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
Mb0121|M.bovis_AF2122/97 NVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTL
Rv0117|M.tuberculosis_H37Rv NVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTL
MAV_1538|M.avium_104 GVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEI
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
. *: * :. * . . .
Mflv_3565|M.gilvum_PYR-GCK AIGTVT-LHPMNVAHLIAEFHADHPDVEITLGT-ATSDVLIAELGDGRLD
Mvan_3362|M.vanbaalenii_PYR-1 AIGTVT-LHPVDVARLMADFHAEHPGVEITLGT-DTSDVLLAKLEDGRLD
MSMEG_3840|M.smegmatis_MC2_155 VVGTVT-AHDFDMAGLLAEFHGAHQLVDITLGT-DESDALIDGLLAGRLD
MAB_3208c|M.abscessus_ATCC_199 AIGTVP-HPSPLLAEALAAYRRAHPAVTVTLTE-ARSDQLATAVVERRLD
MMAR_4157|M.marinum_M ALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQ-RSGQGVLSDLVSGVTD
MUL_4020|M.ulcerans_Agy99 ALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQ-RSGQGVLSDLVSGVTD
Mb0121|M.bovis_AF2122/97 RLGTVP-TASTTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELD
Rv0117|M.tuberculosis_H37Rv RLGTVP-TASTTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELD
MAV_1538|M.avium_104 RLAYLSSFGSTVVPRLIARFKESSPRVTFTLEE-GAAESIADRVRSGGVD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVE-DQTEHLLTALREGALD
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYPSTSFTLRQ-LYPDALTDAVFDGTVQ
:. : . : : : :
Mflv_3565|M.gilvum_PYR-GCK LAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHRRSLSLEQLSRHP
Mvan_3362|M.vanbaalenii_PYR-1 AAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARRKSLSLKQLCEYP
MSMEG_3840|M.smegmatis_MC2_155 AAIISVGSG-LPEGLAAEVVTDQRIVAAVGDGHPWRRRRRIALTDLAGVP
MAB_3208c|M.abscessus_ATCC_199 MAVMAWLAQ-PPSQLRERILAKENIVAVVHRDDPLAGRESVALAELRDRA
MMAR_4157|M.marinum_M VSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRLIRFPELAAYP
MUL_4020|M.ulcerans_Agy99 VSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRLIRFPELAAYP
Mb0121|M.bovis_AF2122/97 AVIVHPETQ-DSDDVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLP
Rv0117|M.tuberculosis_H37Rv AVIVHPETQ-DSDDVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLP
MAV_1538|M.avium_104 IGVVSPRPV--ERTLAWRSLFRQRLGVAVPDGHRFARGAAVSMVDLADEP
MLBr_02041|M.leprae_Br4923 AAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLP
TH_3504|M.thermoresistible__bu LGLRRGVVP--TPELATAVIGYHRVRVAFVDSHPLAARESVDITELAREQ
: : : . :
Mflv_3565|M.gilvum_PYR-GCK LISLPAG--TGLRTRLDTACAAAGLRPRIA-FEATSPAELAELARHGLGV
Mvan_3362|M.vanbaalenii_PYR-1 VISLPAG--TGLRSRLDDACAAAGLRPRIA-FEATSPLELADLARHGLGV
MSMEG_3840|M.smegmatis_MC2_155 LITLPRG--TGIRRQLDRACRAAGVDVRVA-FEATTPGALADLAERGLGA
MAB_3208c|M.abscessus_ATCC_199 LISHPQG--CEIRTALDQACLATGFTPRVV-FETSSADMMRHLVVRDLGV
MMAR_4157|M.marinum_M FVVLDRD--HTLRRIVDAACARHGIDPTLA-FEGTDVGTLRGLIGANLGV
MUL_4020|M.ulcerans_Agy99 FVVLDRD--HTLRRIVDAACARHGIDPTPA-FEGTDVGTLRGLIGANLGV
Mb0121|M.bovis_AF2122/97 LALLTAD--MRDRQVIDAAFADHAVSAIPQ-VETDSVASLFAQVATGNWA
Rv0117|M.tuberculosis_H37Rv LALLTAD--MRDRQVIDAAFADHAVSAIPQ-VETDSVASLFAQVATGNWA
MAV_1538|M.avium_104 FVTMHPG--FGMRRLLDELCAAAQFRPRVA-LQAPNLTTAASLVAAGLGI
MLBr_02041|M.leprae_Br4923 LLLLDEG--HCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGGLGV
TH_3504|M.thermoresistible__bu VALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATVAAPLTTG-GI
. . . .
Mflv_3565|M.gilvum_PYR-GCK AILPQ-------SMARGGSGLHALRLAP-ELRGRLVWAWRADGAN-PAAR
Mvan_3362|M.vanbaalenii_PYR-1 AILPR-------SMARGSAGLHPLRLSP-ELRGRLVWAWRTDISG-PAAR
MSMEG_3840|M.smegmatis_MC2_155 AVLPE-------SVARARAALHPLPITP-ELRGRLVFAWRATGPMSPAAR
MAB_3208c|M.abscessus_ATCC_199 AVTPR-------LPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVA
MMAR_4157|M.marinum_M GVLPQ-------ATARP-ADIIEIAIDDAQLVRPIAIGWIADRCLPSSAV
MUL_4020|M.ulcerans_Agy99 GVLPQ-------ATARP-ADIIEIAIDDAQLVRPIAIGWIADRCLPSSAV
Mb0121|M.bovis_AF2122/97 SIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVAR
Rv0117|M.tuberculosis_H37Rv SIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVAR
MAV_1538|M.avium_104 SLVPID-------GSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSAR
MLBr_02041|M.leprae_Br4923 TLLPQS----AAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYR
TH_3504|M.thermoresistible__bu AFVTAA------AGPTMNGRVQVVDLTPPLLVP-VQALWQRHTLSAIRDR
. . . : : :
Mflv_3565|M.gilvum_PYR-GCK VLGERARAMAVSPGSGAPAVVPGA--
Mvan_3362|M.vanbaalenii_PYR-1 LLNARARAMIAATG--TPAVIPGA--
MSMEG_3840|M.smegmatis_MC2_155 ALVTMARRRLGLGD---PDRVGGHE-
MAB_3208c|M.abscessus_ATCC_199 FAACIDELCRKDAN-----LVS----
MMAR_4157|M.marinum_M AFRETALGCYGHRVS-----AAGV--
MUL_4020|M.ulcerans_Agy99 AFRETAFGCYGHRDS-----AAGV--
Mb0121|M.bovis_AF2122/97 ALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv ALITCAQALALNEFFDTQLRGITRRR
MAV_1538|M.avium_104 DFIAGAAAVGHGGW------------
MLBr_02041|M.leprae_Br4923 QIAKIIGELISTEHHVRLVA------
TH_3504|M.thermoresistible__bu ILEGLG--------------------