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VDTRRLRLLLALSRLGSMRAVADAFSLTTSTVSQQLAALAKETDTQLIEPDGRRVRLTPAGRRLADHAVT ILAAVDAARLDLDPDAEPAGTLRVGGFATGLRVSLLPILRELGRTHPSVEVEISEYEPLEAFELLVDDDL DLALTYEYDLAPASPDPVLEAFPLWSTPWGLGVPSSEVTAGTATADIRNYADRWWIVNSRNTADEDAVRT LASLAGFRPRIAHQIDSLDLLEDLILEGFGVGLLPITRAVRDGVTVMPMSDPKVVLTAFAVVRRGRSTWP PLRLVLDRLRPPDGRPVPLMSWPRPTVHGSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3260 | - | - | 100% (311) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6840 | - | 4e-27 | 32.40% (287) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4609 | - | 5e-17 | 25.67% (300) | transcriptional regulator LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 8e-11 | 25.35% (217) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 4e-16 | 29.00% (300) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 8e-11 | 25.35% (217) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-10 | 25.27% (273) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0678 | - | 1e-22 | 33.20% (250) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4117 | - | 4e-27 | 34.15% (287) | putative regulatory protein |
| M. avium 104 | MAV_2838 | - | 3e-15 | 26.37% (273) | hydrogen peroxide-inducible genes activator |
| M. thermoresistible (build 8) | TH_0172 | - | 1e-08 | 26.64% (214) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_3983 | - | 2e-26 | 33.80% (287) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 1e-118 | 71.48% (305) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3260|M.smegmatis_MC2_155 -------MDTRRLRLLLALSRLGSMRAVADAFSLTTSTVSQQLAALAKET
Mvan_3401|M.vanbaalenii_PYR-1 -------MDTRRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDT
MMAR_4117|M.marinum_M ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
MUL_3983|M.ulcerans_Agy99 ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
MAV_2838|M.avium_104 MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGL
Mb0384|M.bovis_AF2122/97 -------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
Rv0377|M.tuberculosis_H37Rv -------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
TH_0172|M.thermoresistible__bu -------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
MAB_0678|M.abscessus_ATCC_1997 -------MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREA
Mflv_1346|M.gilvum_PYR-GCK -------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLEREV
: . . .* . :* : *
MSMEG_3260|M.smegmatis_MC2_155 DTQLIEPDGRRVRLTPAGRRLADHAVTILAAVDAARLDLDP-DAEPAGTL
Mvan_3401|M.vanbaalenii_PYR-1 GAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDP-DAEPAGTV
MMAR_4117|M.marinum_M GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
MUL_3983|M.ulcerans_Agy99 GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
MAV_2838|M.avium_104 GTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGM
Mb0384|M.bovis_AF2122/97 DDPLFTRTGAGLAFTPGGLRLASRAVEILG-LQQQTAIEVTEAAHGRRLL
Rv0377|M.tuberculosis_H37Rv DDPLFTRTGAGLAFTPGGLRLASRAVEILG-LQQQTAIEVTEAAHGRRLL
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILG-LQRQTAIEVTEAAHGRRLL
MAB_0678|M.abscessus_ATCC_1997 GVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADEEMVAYREGTQPVV
Mflv_1346|M.gilvum_PYR-GCK GADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAEGRL
. *. : .* * : :: : : :
MSMEG_3260|M.smegmatis_MC2_155 RVGGFATGLRVSLLPILRELGRTHPSVEVEIS-EYEPLEAFELLVDDDLD
Mvan_3401|M.vanbaalenii_PYR-1 RVGGFATGIRVSLLPIVADLAVRYPEVDVVIS-EYEPVEAFKLLTADDLD
MMAR_4117|M.marinum_M RVAAFQTLLLSLLPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
MUL_3983|M.ulcerans_Agy99 RVAAFRTLLLSLPPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVV-EDQTEHLLTALREGALD
MAV_2838|M.avium_104 RLGLIPTVAPYVLPTVLAGIAERRPGLTLRVT-EDQTERLLAVLREGALD
Mb0384|M.bovis_AF2122/97 RIAASSAFAEHAAPGLIELFSSRADDLSVELS-VHPTSRFRELICSRAVD
Rv0377|M.tuberculosis_H37Rv RIAASSAFAEHAAPGLIELFSSRADDLSVELS-VHPTSRFRELICSRAVD
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFSSRADDLSVELT-VEPVSRFRDLLESRAVD
MAB_0678|M.abscessus_ATCC_1997 RVASFPSGAGVLLPRVVAAVA---EAVDIRPS-DEDVTYGEAPGLLTEYD
Mflv_1346|M.gilvum_PYR-GCK VVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQLAALHAKDID
:. : :: . : : *
MSMEG_3260|M.smegmatis_MC2_155 LALTYEYDLAPASPDPVLEAFPLWSTPWGLGVPSSEVTAGTATADIRNYA
Mvan_3401|M.vanbaalenii_PYR-1 LALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSG----TAADRGLMTFA
MMAR_4117|M.marinum_M VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIG--PWSDATTLSDLE
MUL_3983|M.ulcerans_Agy99 VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIG--PWSDATTLSDLE
MLBr_02041|M.leprae_Br4923 AAM-----IALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALA
MAV_2838|M.avium_104 AAL-----IALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALA
Mb0384|M.bovis_AF2122/97 IAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSP--LAAGIPMPALLR
Rv0377|M.tuberculosis_H37Rv IAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSP--LAAGIPMPALLR
TH_0172|M.thermoresistible__bu VTLGPAVRE---PGPAIVVRPFLNYQIIAVTSPSNP--LAAATPTIAQLR
MAB_0678|M.abscessus_ATCC_1997 LVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAACDSVTPAELA
Mflv_1346|M.gilvum_PYR-GCK LALMR-----PPVDDPALTAVSLRRDRLLVALPAGHRCADRDEVSLADLR
.: . . : :
MSMEG_3260|M.smegmatis_MC2_155 DRWWIVNSRN--TADEDAVRTLASLAGFRPRIA-HQIDSLDLLEDLILEG
Mvan_3401|M.vanbaalenii_PYR-1 DSTWIVNSRN--TADETAVRTLASLAGFTPTIA-HQIDSLDLVEDLIVAG
MMAR_4117|M.marinum_M YASWALDPEP--TVPGRWARSVCRAAGFEPDVR-FDGVDLLVHLQMVQAG
MUL_3983|M.ulcerans_Agy99 YASWALDPEP--TVPGRWARSVCRAAGFEPDVR-FDGVDLLVHLQMVQAG
MLBr_02041|M.leprae_Br4923 QLPLLLLDEG--HCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGG
MAV_2838|M.avium_104 DLPLLLLDEG--HCLRDQALDVCHKAGVRAELANTRAASLATAVQCVTGG
Mb0384|M.bovis_AF2122/97 HQQWMLGPSA--GSVDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVG
Rv0377|M.tuberculosis_H37Rv HQQWMLGPSA--GSVDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVG
TH_0172|M.thermoresistible__bu AQSWMLGPSA--GGIDGDVAAMLRRLEIPEAAQRIFQSDSAAQEEVQRIG
MAB_0678|M.abscessus_ATCC_1997 DETWISVPEG--FPVDDVLVSLGVSTGIIPRVR-FRFKDFQIVEDMVAHG
Mflv_1346|M.gilvum_PYR-GCK DEDFISHAGGGRSRMSALLAALCADAGFSPRIR-DEVDETSTLVTLVAGG
: . . *
MSMEG_3260|M.smegmatis_MC2_155 FGVGLLP----ITRAVRDGVTVMPMSDPKVVLTAFAVVRRGRSTWPPLRL
Mvan_3401|M.vanbaalenii_PYR-1 FGVGLLP----LGRPTSPGVTVLPLQNPDVTLTAYAVTRRGRSAWSPLRA
MMAR_4117|M.marinum_M LAVAILPA--LLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAVVA
MUL_3983|M.ulcerans_Agy99 LAVAILPA--LLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAVVA
MLBr_02041|M.leprae_Br4923 LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQ
MAV_2838|M.avium_104 LGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSYRE
Mb0384|M.bovis_AF2122/97 -GATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
Rv0377|M.tuberculosis_H37Rv -GATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
TH_0172|M.thermoresistible__bu -GVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSAARQPAASE
MAB_0678|M.abscessus_ATCC_1997 HGVALMPR----YASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAA
Mflv_1346|M.gilvum_PYR-GCK LGVALVPEP--TAALEIGGVTYRPLAAKAGATIELLAVYRSADASPLTAK
.. : :
MSMEG_3260|M.smegmatis_MC2_155 VLDRLRPPDGRPVPLMSWPRP---TVHGSG-----
Mvan_3401|M.vanbaalenii_PYR-1 ILDRMRPPAG-LLQHPTWPRPEAAVANQSA-----
MMAR_4117|M.marinum_M FRTALAEGFDAQHQYD-------------------
MUL_3983|M.ulcerans_Agy99 FRTALAEGFDAQHQYD-------------------
MLBr_02041|M.leprae_Br4923 IAKIIGELISTEHHVRLVA----------------
MAV_2838|M.avium_104 LAGLIGELISSQHQVRLVK----------------
Mb0384|M.bovis_AF2122/97 LVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv LVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
TH_0172|M.thermoresistible__bu LVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
MAB_0678|M.abscessus_ATCC_1997 TIQGLRDAAAVLESR--------------------
Mflv_1346|M.gilvum_PYR-GCK VVDVLRATV--------------------------
: