For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DQWTSQLAPQLRALVELAAHDGHMTQAALTLGIPQSSMSRRIHALQAALGVPLLIHDGRTVRLTPEARLL AARTREPLAELDHTLSEVTGDADPERGTVRFGFPLTMGSGHIPDLLAAFRHRHPGIRVLLKQAHGSELGA QLLTGDLDLAVVIPAPERLHHITIGAQHIHIAVPEDHRLAGAAQVRLRELSGETFIANPPSYNLRQLTER WCREAGYAPNVTIEVTEFSTIRELIGRGLGVALLPHDDRALPGIREIPLAGDGYHRAIALAWGTATRAAP TRRLNDFLLQHFSQAEVNSAAIRKG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2680c | - | - | 100% (306) | LysR family transcriptional regulator |
M. abscessus ATCC 19977 | MAB_2707 | - | 2e-35 | 33.33% (255) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_2238 | - | 1e-23 | 32.64% (239) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2303c | - | 2e-09 | 24.07% (295) | LysR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_3565 | - | 9e-23 | 31.56% (282) | LysR family transcriptional regulator |
M. tuberculosis H37Rv | Rv2282c | - | 2e-09 | 24.07% (295) | LysR family transcriptional regulator |
M. leprae Br4923 | MLBr_02041 | oxyR | 2e-21 | 28.37% (282) | putative LysR-family transcriptional regulator |
M. marinum M | MMAR_4157 | - | 7e-25 | 29.63% (270) | LuxR family transcriptional regulator |
M. avium 104 | MAV_1538 | - | 6e-32 | 29.37% (269) | transcriptional regulator, LysR family protein |
M. smegmatis MC2 155 | MSMEG_0104 | - | 6e-40 | 35.16% (256) | transcriptional regulator, LysR family protein |
M. thermoresistible (build 8) | TH_3083 | - | 2e-09 | 30.72% (153) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4020 | - | 1e-24 | 29.63% (270) | LuxR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_3362 | - | 2e-22 | 30.39% (283) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI MMAR_4157|M.marinum_M -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI MUL_4020|M.ulcerans_Agy99 -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV MAV_1538|M.avium_104 -------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRL MSMEG_0104|M.smegmatis_MC2_155 -------MHLDELSWFVVLAETEHVTDAAAELGISQPTLSRALARLEDEV MAB_2680c|M.abscessus_ATCC_199 MDQWTSQLAPQLRALVELAAHDGHMTQAALTLGIPQSSMSRRIHALQAAL MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL TH_3083|M.thermoresistible__bu -------------------------------------------------- Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI MMAR_4157|M.marinum_M GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV MUL_4020|M.ulcerans_Agy99 GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSV Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV MAV_1538|M.avium_104 GVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEI MSMEG_0104|M.smegmatis_MC2_155 GVPLFDRVNRRLQLNAYGEILLEHARRTITEMRSATERIAAMRDPDTGLV MAB_2680c|M.abscessus_ATCC_199 GVPLLIHDGRTVRLTPEARLLAARTREPLAELDHTLSEVTGDADPERGTV MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM TH_3083|M.thermoresistible__bu -------------------------------------------------V : Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTA-TNSEHAIAAVR Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTA-TNSEHAIAAVR MMAR_4157|M.marinum_M ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQ-RSGQGVLSDLV MUL_4020|M.ulcerans_Agy99 ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQ-RSGQGVLSDLV Mflv_3565|M.gilvum_PYR-GCK AIGTVT-LHPMNVAHLIAEFHADHPD-----VEITLGT-ATSDVLIAELG Mvan_3362|M.vanbaalenii_PYR-1 AIGTVT-LHPVDVARLMADFHAEHPG-----VEITLGT-DTSDVLLAKLE MAV_1538|M.avium_104 RLAYLSSFGSTVVPRLIARFKESSPR-----VTFTLEE-GAAESIADRVR MSMEG_0104|M.smegmatis_MC2_155 RLAFLHSQAGSFVPDLLRRFRAHAPH-----VQFSLTQ-GAAHDLLERLA MAB_2680c|M.abscessus_ATCC_199 RFGFPLTMGSGHIPDLLAAFRHRHPG-----IRVLLKQ-AHGSELGAQLL MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPT-----LTLRVVE-DQTEHLLTALR TH_3083|M.thermoresistible__bu RITFPGMSTHPHVARLARVVRSQRPG-----IRLELSSQNFAQPAMQKLV . :. . : : Mb2303c|M.bovis_AF2122/97 DGIADLGFIENPCPPT--GLGSVVVARDELVVVVPPGHKWARRSRVVSAR Rv2282c|M.tuberculosis_H37Rv DGIADLGFIENPCPPT--GLGSVVVARDELVVVVPPGHKWARRSRVVSAR MMAR_4157|M.marinum_M SGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP MUL_4020|M.ulcerans_Agy99 SGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP Mflv_3565|M.gilvum_PYR-GCK DGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLE Mvan_3362|M.vanbaalenii_PYR-1 DGRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLK MAV_1538|M.avium_104 SGGVDIGVVSPRPVER--TLAWRSLFRQRLGVAVPDGHRFARG-AAVSMV MSMEG_0104|M.smegmatis_MC2_155 GGQVDLAITSPRPEG----FQWRGLYVERLCLAVPRGHRLASR-SRITLA MAB_2680c|M.abscessus_ATCC_199 TGDLDLAVVIPAPER----LHHITIGAQHIHIAVPEDHRLAGA-AQVRLR MLBr_02041|M.leprae_Br4923 EGALDAAMIALPVETAG--IAEIPIYDEDFVLALPPGHPLSGK-RRVPTT TH_3083|M.thermoresistible__bu RSETDIALGRWDLIPAD--VSSRIVMRDELVVALPEDHALAGR-GRVSAG . * .. . : : . .:. * : : Mb2303c|M.bovis_AF2122/97 ELAQTPLVTREPNSG--IRDSLTAALRDTLGEDMQQAPPVLELSSAAAVR Rv2282c|M.tuberculosis_H37Rv ELAQTPLVTREPNSG--IRDSLTAALRDTLGEDMQQAPPVLELSSAAAVR MMAR_4157|M.marinum_M ELAAYPFVVLDRDHT--LRRIVDAACARHG----IDPTLAFEGTDVGTLR MUL_4020|M.ulcerans_Agy99 ELAAYPFVVLDRDHT--LRRIVDAACARHG----IDPTPAFEGTDVGTLR Mflv_3565|M.gilvum_PYR-GCK QLSRHPLISLPAGTG--LRTRLDTACAAAG----LRPRIAFEATSPAELA Mvan_3362|M.vanbaalenii_PYR-1 QLCEYPVISLPAGTG--LRSRLDDACAAAG----LRPRIAFEATSPLELA MAV_1538|M.avium_104 DLADEPFVTMHPGFG--MRRLLDELCAAAQ----FRPRVALQAPNLTTAA MSMEG_0104|M.smegmatis_MC2_155 DAGDEPFVGLAPGFG--LRQLTEELCAEAG----ITPHVVFEATEIPTME MAB_2680c|M.abscessus_ATCC_199 ELSGETFIANPPSYN--LRQLTERWCREAG----YAPNVTIEVTEFSTIR MLBr_02041|M.leprae_Br4923 ALAQLPLLLLDEGHC--LRDQTLDICRKSG---VQAELANTRAASLATAV TH_3083|M.thermoresistible__bu ELAGESFVSLPPYEGSVLPDRLRRLAHANG----FVPEVVQIAPDTQTAL ..: : .. Mb2303c|M.bovis_AF2122/97 AAVLAGAGPAAMSRLAIADDLA--FGRLLAVDIPALNLRRQLRAIWVGGR Rv2282c|M.tuberculosis_H37Rv AAVLAGAGPAAMSRLAIADDLA--FGRLLAVDIPALNLRRQLRAIWVGGR MMAR_4157|M.marinum_M GLIGANLGVGVLPQATARPAD------IIEIAIDDAQLVRPIAIGWIADR MUL_4020|M.ulcerans_Agy99 GLIGANLGVGVLPQATARPAD------IIEIAIDDAQLVRPIAIGWIADR Mflv_3565|M.gilvum_PYR-GCK ELARHGLGVAILPQSMARGGS------GLHALRLAPELRGRLVWAWRADG Mvan_3362|M.vanbaalenii_PYR-1 DLARHGLGVAILPRSMARGSA------GLHPLRLSPELRGRLVWAWRTDI MAV_1538|M.avium_104 SLVAAGLGISLVPIDGSSYPS---G--VSVKPLADADAYRDVGMIWDSGR MSMEG_0104|M.smegmatis_MC2_155 GLVAAGFGVAVVPVPHAGRAEP--G--AEYIALAQASAKRQLGLAWPADR MAB_2680c|M.abscessus_ATCC_199 ELIGRGLGVALLPHDDRALPG------IREIPLAGDGYHRAIALAWGTAT MLBr_02041|M.leprae_Br4923 QCVTGGLGVTLLPQSAAPVESV--RSKLGLAQFAAPCPGRRIGLAFRSAS TH_3083|M.thermoresistible__bu ALVSAQVGCHLTFASVARNATDPHVVFVPLEGAAEADVDVDLRAAWRRDD * : : Mb2303c|M.bovis_AF2122/97 TPPAGAIRDLLSHITSRST----------- Rv2282c|M.tuberculosis_H37Rv TPPAGAIRDLLSHITSRST----------- MMAR_4157|M.marinum_M CLPSSAVAFRETALGCYGHRVSAAGV---- MUL_4020|M.ulcerans_Agy99 CLPSSAVAFRETAFGCYGHRDSAAGV---- Mflv_3565|M.gilvum_PYR-GCK ANPAARVLGERARAMAVSPGSGAPAVVPGA Mvan_3362|M.vanbaalenii_PYR-1 SGPAARLLNARARAMIAATG--TPAVIPGA MAV_1538|M.avium_104 PLPRSARDFIAGAAAVGHGGW--------- MSMEG_0104|M.smegmatis_MC2_155 PLPPAAERFAQFVIRTTHDVE--------- MAB_2680c|M.abscessus_ATCC_199 RAAPTRRLNDFLLQHFSQAEVNSAAIRKG- MLBr_02041|M.leprae_Br4923 GRSASYRQIAKIIGELISTEHHVRLVA--- TH_3083|M.thermoresistible__bu RSPAVHAVLECLFDDAGVENR--------- .