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PLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVV AEWAARLLEVADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNS EHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNS GIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNL RRQLRAIWVGGRTPPAGAIRDLLSHITSRST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2282c | - | - | 100% (312) | Probable transcription regulator (lysR family) |
| M. tuberculosis H37Rv | Rv0377 | - | 7e-10 | 26.09% (276) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1985c | - | 3e-07 | 25.75% (268) | chromosome replication initiation inhibitor protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-172 | 100.00% (312) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 1e-14 | 29.27% (246) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 3e-17 | 27.23% (213) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 6e-56 | 42.35% (307) | LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 1e-138 | 81.23% (309) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 1e-138 | 80.71% (311) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2797 | - | 1e-108 | 66.34% (309) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 2e-09 | 26.42% (265) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-137 | 80.91% (309) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 1e-12 | 27.80% (205) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1346|M.gilvum_PYR-GCK -------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLEREV
Mvan_1027|M.vanbaalenii_PYR-1 ------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSRQVQQLENEL
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
MSMEG_2797|M.smegmatis_MC2_155 MPLSSRMPELAAFDVLLAIARTGSLGAAGRELGLTQQAVSARLASIEAQT
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_0172|M.thermoresistible__bu -------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
: : ::.. . *. : : * : :.
Mflv_1346|M.gilvum_PYR-GCK GADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAEGRL
Mvan_1027|M.vanbaalenii_PYR-1 GVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKRIPAGDLGTV
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
MSMEG_2797|M.smegmatis_MC2_155 GVRLVQRSSRGSQLTQAGVVVAEWADQLLEVAQRVDAGLAALRSESHTRL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHG-RRLL
* * .* * . : : :
Mflv_1346|M.gilvum_PYR-GCK VVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQ----LAALHA
Mvan_1027|M.vanbaalenii_PYR-1 VVGFTAASAHAVLPRLLERARERLPDVKLDLR-EMVTAAQ----IEGLMT
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
MSMEG_2797|M.smegmatis_MC2_155 TVAASLTIAEQLMPRWLVSLHADARRRGVPTPEVILTAANSEDVIGAVRD
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALRARH-----ADVAVSLEVGNTQQVCELVRA
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLP-----TLTLRVVEDQTEHLLTALRE
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFSSRAD-----DLSVELTVEPVSRFRDLLES
: : : * : : :
Mflv_1346|M.gilvum_PYR-GCK KDIDLALMRPPVDD-PALTAVSLRRDRLLVALPAGHRCADRD-EVSLADL
Mvan_1027|M.vanbaalenii_PYR-1 GELDLGMARPPLKR-PGLVSRPLLHEQLLAALPEGHPLADMTRELTLIDL
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCPP-TGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCPP-TGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
MMAR_3419|M.marinum_M GTADLGFVENPGPP-TGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTAREL
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGPP-TGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTAREL
MAV_2151|M.avium_104 GSADLGFVENPGTP-KGLGSCVVGEDELVIVVPPTHKWARRSRVVTAREL
MSMEG_2797|M.smegmatis_MC2_155 GSAELGFIESPGTP-RGLHTRVVARDELIVVVPPGHKWDRRSTPIGPAEL
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHAP-TGLGGEVLGADELVIVVGPGHKWAHRRKPVTLREL
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVET-AGIAEIPIYDEDFVLALPPGHPLSGKR-RVPTTAL
TH_0172|M.thermoresistible__bu RAVDVTLGPAVREPGPAIVVRPFLNYQIIAVTSPSNPLAAAT--PTIAQL
. : .: . :: . : *
Mflv_1346|M.gilvum_PYR-GCK RDEDFISHAGGG--RSRMSALLAALCADAGFSPRIRDEVDETSTLVTLVA
Mvan_1027|M.vanbaalenii_PYR-1 DGQDFVMYSPVQ--ARYFNELLISTFTIAGTTPRYVQYVTQVHTMLVLVR
Rv2282c|M.tuberculosis_H37Rv AQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
Mb2303c|M.bovis_AF2122/97 AQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
MMAR_3419|M.marinum_M AETPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAVL
MUL_2698|M.ulcerans_Agy99 AEMPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAVL
MAV_2151|M.avium_104 AQTPLVAREPHSGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAVL
MSMEG_2797|M.smegmatis_MC2_155 NDTPLVSREAGSGTREALSTALRRALG-DTTQAAPAIELSSAAAMRAAVA
MAB_3458c|M.abscessus_ATCC_199 AITPLLMREPGSGTRD----TVWEVLSEVCQPATPAAELGSAAAIKAAAA
MLBr_02041|M.leprae_Br4923 AQLPLLLLDEGHCLRDQTLDICRKSGVQAELAN---TRAASLATAVQCVT
TH_0172|M.thermoresistible__bu RAQSWMLGPSAGGIDGDVAAMLRRLEIPEAAQR----IFQSDSAAQEEVQ
: . : .
Mflv_1346|M.gilvum_PYR-GCK GGLGVALVPEPTAALEIGGVTYRPLA---AKAGATIELLAVYRSADASPL
Mvan_1027|M.vanbaalenii_PYR-1 SGIGIALVPASAATLHPEGVVFRTIG---AFRERPVELDAVWRGDSTNPA
Rv2282c|M.tuberculosis_H37Rv AGAGPAAMSRLAIADDLAFGRLLAVD--IPALNLRRQLRAIWVGGRTPPA
Mb2303c|M.bovis_AF2122/97 AGAGPAAMSRLAIADDLAFGRLLAVD--IPALNLRRQLRAIWVGGRTPPA
MMAR_3419|M.marinum_M AGAGPAAMSRLAIADDLAVGRLRAIS--IPGLDLRRQLRAIWVGGRVPPA
MUL_2698|M.ulcerans_Agy99 AGAGPAAMSRLAIADDLAVGRLRAIS--IPGLDLRRQLRAIWVGGRVPPA
MAV_2151|M.avium_104 AGAGPAAMSRLAVADDLAVGRLHAVE--IPKLDLRRKFRAIWIGGRTPPA
MSMEG_2797|M.smegmatis_MC2_155 AGAGPAVMSRLAVEDDLTLGRLRAVP--VAGLDLRRDLRAVWSGTRTPPA
MAB_3458c|M.abscessus_ATCC_199 TGLAPAVLSRLIAGPELSAGTLVEVKP-ADGTVFTRQFRAVWRPG-APPT
MLBr_02041|M.leprae_Br4923 GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASY
TH_0172|M.thermoresistible__bu RIGGVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSAARQPAA
. : . . .
Mflv_1346|M.gilvum_PYR-GCK -TAKVV-DVLRATV-----------------------
Mvan_1027|M.vanbaalenii_PYR-1 -LLRVLKDVLPQQEWTT--------------------
Rv2282c|M.tuberculosis_H37Rv GAIRDLLSHITSRST----------------------
Mb2303c|M.bovis_AF2122/97 GAIRDLLSHITSRST----------------------
MMAR_3419|M.marinum_M GAIRELLSHITSGGE----------------------
MUL_2698|M.ulcerans_Agy99 GAIRELLSHITSGGE----------------------
MAV_2151|M.avium_104 GAIRDLLSHIIARTAASK-------------------
MSMEG_2797|M.smegmatis_MC2_155 GAVRDLLGHIAAAR-----------------------
MAB_3458c|M.abscessus_ATCC_199 GAARALVDIAALVD-----------------------
MLBr_02041|M.leprae_Br4923 RQIAKIIGELISTEHHVRLVA----------------
TH_0172|M.thermoresistible__bu SELVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
.