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LNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLERECGMALIEPVGRGVRLTDAGEALVEHTRL AIATLERAEALLAASQGRVAGRLRVAAFRTLLLSLPPRVLDALARDYPDLRVEVAQREADEATSGLLAGT FDVVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIGPWSDATTLSDLEYASWALDPEPTVPGRWARSV CRAAGFEPDVRFDGVDLLVHLQMVQAGLAVAILPALLGQDRMRGVRLAPLPASPKRQLFTLTRTSRTAHP AVVAFRTALAEGFDAQHQYD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3983 | - | - | 100% (301) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_4020 | - | 7e-12 | 26.29% (232) | LuxR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 8e-09 | 28.57% (175) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 2e-07 | 26.59% (173) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 1e-15 | 30.24% (248) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-07 | 26.59% (173) | LysR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0678 | - | 9e-22 | 31.47% (286) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4117 | - | 1e-167 | 99.34% (301) | putative regulatory protein |
| M. avium 104 | MAV_1538 | - | 1e-12 | 25.29% (261) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3260 | - | 3e-26 | 33.80% (287) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 4e-07 | 25.53% (188) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 1e-27 | 34.98% (283) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MUL_3983|M.ulcerans_Agy99 ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
MMAR_4117|M.marinum_M ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
MSMEG_3260|M.smegmatis_MC2_155 -------MDTRRLRLLLALSRLGSMRAVADAFSLTTSTVSQQLAALAKET
Mvan_3401|M.vanbaalenii_PYR-1 -------MDTRRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDT
MAB_0678|M.abscessus_ATCC_1997 -------MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREA
Mflv_1346|M.gilvum_PYR-GCK -------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLEREV
MAV_1538|M.avium_104 -------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRL
TH_0172|M.thermoresistible__bu -------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
: . . .* : :: : :
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MUL_3983|M.ulcerans_Agy99 GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
MMAR_4117|M.marinum_M GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
MSMEG_3260|M.smegmatis_MC2_155 DTQLIEPDGRRVRLTPAGRRLADHAVTILAAVDAARLDLDP-DAEPAGTL
Mvan_3401|M.vanbaalenii_PYR-1 GAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDP-DAEPAGTV
MAB_0678|M.abscessus_ATCC_1997 GVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADEEMVAYREGTQPVV
Mflv_1346|M.gilvum_PYR-GCK GADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAEGRL
MAV_1538|M.avium_104 GVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEI
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHGRR-LL
. * . :. * . : :
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVP-EVILTATNSEHAIAAVR
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVP-EVILTATNSEHAIAAVR
MUL_3983|M.ulcerans_Agy99 RVAAFRTLLLSLPPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
MMAR_4117|M.marinum_M RVAAFQTLLLSLLPRVLDALARDYPDLRVEVA-QREADEATSGLLAGTFD
MSMEG_3260|M.smegmatis_MC2_155 RVGGFATGLRVSLLPILRELGRTHPSVEVEIS-EYEPLEAFELLVDDDLD
Mvan_3401|M.vanbaalenii_PYR-1 RVGGFATGIRVSLLPIVADLAVRYPEVDVVIS-EYEPVEAFKLLTADDLD
MAB_0678|M.abscessus_ATCC_1997 RVASFPSGAGVLLPRVVAAVAEA---VDIRPS-DEDVTYGEAPGLLTEYD
Mflv_1346|M.gilvum_PYR-GCK VVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQLAALHAKDID
MAV_1538|M.avium_104 RLAYLSSFGSTVVPRLIARFKESSPRVTFTLE-EGAAESIADRVRSGGVD
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFSSRADDLSVELT-VEPVSRFRDLLESRAVD
: : : .
Mb2303c|M.bovis_AF2122/97 DGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
Rv2282c|M.tuberculosis_H37Rv DGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
MUL_3983|M.ulcerans_Agy99 VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIGPWSDATTLSDLEYA
MMAR_4117|M.marinum_M VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIGPWSDATTLSDLEYA
MSMEG_3260|M.smegmatis_MC2_155 LALTYEYDLAPASPDPVLEAFPLWSTPWGLGVPSSEVTAGTATADIRNYA
Mvan_3401|M.vanbaalenii_PYR-1 LALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSG----TAADRGLMTFA
MAB_0678|M.abscessus_ATCC_1997 LVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAACDSVTPAELA
Mflv_1346|M.gilvum_PYR-GCK LALMR-----PPVDDPALTAVSLRRDRLLVALPAGHRCADRDEVSLADLR
MAV_1538|M.avium_104 IGVVS-----PRPVERTLAWRSLFRQRLGVAVPDGHRFARGAAVSMVDLA
TH_0172|M.thermoresistible__bu VTLGP----AVREPGPAIVVRPFLNYQIIAVTSPSNPLAAATPTIAQLRA
: : .
Mb2303c|M.bovis_AF2122/97 AQTPLVTREP--NSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAA
Rv2282c|M.tuberculosis_H37Rv AQTPLVTREP--NSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAA
MUL_3983|M.ulcerans_Agy99 S--WALDPEP--TVPGRWARSVCRAAGFEPDVRFDGVDLLV-----HLQM
MMAR_4117|M.marinum_M S--WALDPEP--TVPGRWARSVCRAAGFEPDVRFDGVDLLV-----HLQM
MSMEG_3260|M.smegmatis_MC2_155 DRWWIVNSRN--TADEDAVRTLASLAGFRPRIAHQIDSLDL-----LEDL
Mvan_3401|M.vanbaalenii_PYR-1 DSTWIVNSRN--TADETAVRTLASLAGFTPTIAHQIDSLDL-----VEDL
MAB_0678|M.abscessus_ATCC_1997 DETWISVPEG--FPVDDVLVSLGVSTGIIPRVRFRFKDFQI-----VEDM
Mflv_1346|M.gilvum_PYR-GCK DEDFISHAGGGRSRMSALLAALCADAGFSPRIRDEVDETST-----LVTL
MAV_1538|M.avium_104 DEPFVTMHPG--FGMRRLLDELCAAAQFRPRVALQAPNLTT-----AASL
TH_0172|M.thermoresistible__bu QSWMLGPSAG---GIDGDVAAMLRRLEIPEAAQRIFQSDSA-----AQEE
:
Mb2303c|M.bovis_AF2122/97 VLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPA
Rv2282c|M.tuberculosis_H37Rv VLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPA
MUL_3983|M.ulcerans_Agy99 VQAGLAVAILPALLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAV
MMAR_4117|M.marinum_M VQAGLAVAILPALLGQDRMRGVRLAPLP-ASPKRQLFTLTRTSRTAHPAV
MSMEG_3260|M.smegmatis_MC2_155 ILEGFGVGLLP--ITRAVRDGVTVMPMSDPKVVLTAFAVVRRGRSTWPPL
Mvan_3401|M.vanbaalenii_PYR-1 IVAGFGVGLLP--LGRPTSPGVTVLPLQNPDVTLTAYAVTRRGRSAWSPL
MAB_0678|M.abscessus_ATCC_1997 VAHGHGVALMPRYASRS--PRVARVVIREVRAARLYEVLARPGARHRPAI
Mflv_1346|M.gilvum_PYR-GCK VAGGLGVALVPEPTAALEIGGVTYRPLAAKAGATIELLAVYRSADASPLT
MAV_1538|M.avium_104 VAAGLGISLVP-IDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSA
TH_0172|M.thermoresistible__bu VQRIGGVTLSIGFAVAKDLAAGRLARIKGVQATAEWCVSTLSSAARQPAA
: . :
Mb2303c|M.bovis_AF2122/97 GAIRDLLSHITSRST----------------------
Rv2282c|M.tuberculosis_H37Rv GAIRDLLSHITSRST----------------------
MUL_3983|M.ulcerans_Agy99 VAFRTALAEGFDAQHQYD-------------------
MMAR_4117|M.marinum_M VAFRTALAEGFDAQHQYD-------------------
MSMEG_3260|M.smegmatis_MC2_155 RLVLDRLRPPDGRPVPLMSWPRP---TVHGSG-----
Mvan_3401|M.vanbaalenii_PYR-1 RAILDRMRPPAG-LLQHPTWPRPEAAVANQSA-----
MAB_0678|M.abscessus_ATCC_1997 AATIQGLRDAAAVLESR--------------------
Mflv_1346|M.gilvum_PYR-GCK AKVVDVLRATV--------------------------
MAV_1538|M.avium_104 RDFIAGAAAVGHGGW----------------------
TH_0172|M.thermoresistible__bu SELVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS