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M. thermoresistible (build 8) TH_3504 (-)

annotation: putative transcriptional regulator
coordinates: 940686 - 941567
length: 294

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3504--100% (294)putative transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2303c-6e-0827.56% (283) LysR family transcriptional regulator
M. gilvum PYR-GCKMflv_3565-9e-2330.97% (268) LysR family transcriptional regulator
M. tuberculosis H37RvRv2282c-6e-0827.56% (283) LysR family transcriptional regulator
M. leprae Br4923MLBr_02041oxyR8e-1525.30% (249) putative LysR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4795c-6e-7347.55% (286) LysR family transcriptional regulator
M. marinum MMMAR_4157-4e-1324.26% (272) LuxR family transcriptional regulator
M. avium 104MAV_2789-3e-1529.18% (281) transcriptional regulator, LysR family protein
M. smegmatis MC2 155MSMEG_4331-1e-10769.96% (283) putative transcriptional regulator
M. ulcerans Agy99MUL_4020-4e-1326.03% (219) LuxR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1027-2e-2530.61% (245) LysR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4157|M.marinum_M               ----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSR
MUL_4020|M.ulcerans_Agy99           ----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSR
Mb2303c|M.bovis_AF2122/97           ----MPLSSR-----MPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSR
Rv2282c|M.tuberculosis_H37Rv        ----MPLSSR-----MPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSR
TH_3504|M.thermoresistible__bu      ----VPSPKI-------DLRRLAQFVAVAELGSFTRAAATLHLSQQALSS
MSMEG_4331|M.smegmatis_MC2_155      ----MP-----------DLRRLRQFVAVADAGSVTAAAAALHLSQQALSS
MAB_4795c|M.abscessus_ATCC_199      ----MPEHSAGIWDDPVDLRRLQQFLSVAEHSGFTRAAQQLRLTQQAISQ
Mflv_3565|M.gilvum_PYR-GCK          ----------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSA
Mvan_1027|M.vanbaalenii_PYR-1       ---------------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSR
MLBr_02041|M.leprae_Br4923          ---------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQ
MAV_2789|M.avium_104                MKDLCSSGMDVVQAGRVELRHLRAFEAVARLESFTLAAQELSITQPALSR
                                                      :  :  * ::.    .  *:    : * .:* 

MMAR_4157|M.marinum_M               AITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRE
MUL_4020|M.ulcerans_Agy99           AITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRE
Mb2303c|M.bovis_AF2122/97           RLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGS
Rv2282c|M.tuberculosis_H37Rv        RLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGS
TH_3504|M.thermoresistible__bu      AVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQ
MSMEG_4331|M.smegmatis_MC2_155      SIQQLEKQLGATLFHREGRRLRLTRAGEVLLVEGRPLLAAAHTIAARVEQ
MAB_4795c|M.abscessus_ATCC_199      SVTNLEKQVGAKLFDRSGRHIALTPAGEVLRDGSVVLLAAAQTLVRQVQN
Mflv_3565|M.gilvum_PYR-GCK          QIRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDD
Mvan_1027|M.vanbaalenii_PYR-1       QVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKR
MLBr_02041|M.leprae_Br4923          ALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAG
MAV_2789|M.avium_104                TIKQLEDALEASLLDRTSRHVATTPAGRVFLGHVERILTELGRGVDAVRQ
                                     :  :*  :   *  *  *    .  *  .                    

MMAR_4157|M.marinum_M               LAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR----FELHQRSG
MUL_4020|M.ulcerans_Agy99           LAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR----FELHQRSG
Mb2303c|M.bovis_AF2122/97           LRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNS
Rv2282c|M.tuberculosis_H37Rv        LRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNS
TH_3504|M.thermoresistible__bu      TEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTS-----FTLRQLYP
MSMEG_4331|M.smegmatis_MC2_155      TAHRADEAYVIGHTPALSGIEAYTHVERAITAFPDVS-----FTFRQFYP
MAB_4795c|M.abscessus_ATCC_199      TAAEQPRPFVVAHTPAITAEEVHQLLVPVRSALPNVS-----VTALQVFP
Mflv_3565|M.gilvum_PYR-GCK          VAGLLRGSVAIG-TVTLHPMNVAHLIAEFHADHPDVE-----ITLGTATS
Mvan_1027|M.vanbaalenii_PYR-1       IPAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVK-----LDLREMVT
MLBr_02041|M.leprae_Br4923          ESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLT-----LRVVEDQT
MAV_2789|M.avium_104                QAS-----IRLGFSWLLPDPWAQDTVARFERTTRTTVS--------LIRT
                                              :              :                        

MMAR_4157|M.marinum_M               QGVLSDLVSGVTDVS-LSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLA
MUL_4020|M.ulcerans_Agy99           QGVLSDLVSGVTDVS-LSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLA
Mb2303c|M.bovis_AF2122/97           EHAIAAVRDGIADLGFIENPCPPTGLGSVVVAR---DELVVVVPPGHKWA
Rv2282c|M.tuberculosis_H37Rv        EHAIAAVRDGIADLGFIENPCPPTGLGSVVVAR---DELVVVVPPGHKWA
TH_3504|M.thermoresistible__bu      DALTDAVFDGTVQLGLRRGVVPTPELATAVIGY---HRVRVAFVDSHPLA
MSMEG_4331|M.smegmatis_MC2_155      DALVEAVLDGTVHLGLRRGVVPTSAVATAVLGF---DRVRLALPRDHRLA
MAB_4795c|M.abscessus_ATCC_199      NALEPAVIGGSADIALRRGIATPKNLASRVIGY---HALRVAVPREHLLA
Mflv_3565|M.gilvum_PYR-GCK          DVLIAELGDGRLDLAIVSIAVD-EDLPGLEVAVITDEAVEAAVADGHPLA
Mvan_1027|M.vanbaalenii_PYR-1       AAQIEGLMTGELDLGMARPPLKRPGLVSRPLLH---EQLLAALPEGHPLA
MLBr_02041|M.leprae_Br4923          EHLLTALREGALDAAMIALPVETAGIAEIPIYD---EDFVLALPPGHPLS
MAV_2789|M.avium_104                DDALGAVQQGRVDIALVRGHVTSTAVRIVHLFD---EPRVAVCSVHSPLA
                                          :  *  . .                     .    .       :

MMAR_4157|M.marinum_M               GR-RLIRFPELAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTLAF
MUL_4020|M.ulcerans_Agy99           GR-RLIRFPELAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTPAF
Mb2303c|M.bovis_AF2122/97           RRSRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVL
Rv2282c|M.tuberculosis_H37Rv        RRSRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVL
TH_3504|M.thermoresistible__bu      AR-ESVDITELAREQVALWAPPGTSYYSDFLMGACRRAG----FEPDYVV
MSMEG_4331|M.smegmatis_MC2_155      GK-ASVDISDVAGERIALWAPPGASYYSDFLMGACRRAG----FEPDYVV
MAB_4795c|M.abscessus_ATCC_199      ER-DSVALRDLRNERIIVWAPPGVSHYTDFILSTCRSAG----FEPAFVI
Mflv_3565|M.gilvum_PYR-GCK          HR-RSLSLEQLSRHPLISLPAG--TGLRTRLDTACAAAG----LRPRIAF
Mvan_1027|M.vanbaalenii_PYR-1       DMTRELTLIDLDGQDFVMYSPVQARYFNELLISTFTIAG----TTPRYVQ
MLBr_02041|M.leprae_Br4923          GK-RRVPTTALAQLPLLLLDEG--HCLRDQTLDICRKSG---VQAELANT
MAV_2789|M.avium_104                KR-AKLDWAEVPRWPLVINTAS------GTTGPWSWPAG----DGPETIV
                                         :    :    .                                  

MMAR_4157|M.marinum_M               EGTDVGTLRGLIGANLGVGVLPQATARP----ADIIEIAIDDAQLVRPIA
MUL_4020|M.ulcerans_Agy99           EGTDVGTLRGLIGANLGVGVLPQATARP----ADIIEIAIDDAQLVRPIA
Mb2303c|M.bovis_AF2122/97           ELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLR
Rv2282c|M.tuberculosis_H37Rv        ELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLR
TH_3504|M.thermoresistible__bu      SRVQGAATVAAPLTTGGIAFVTAAAGPTMN--GRVQVVDLTPP-LLVPVQ
MSMEG_4331|M.smegmatis_MC2_155      SRVQGAATVAAPLTTDAIAFVTAPAGAAMD--GRVVVVDLQPE-LLVGAQ
MAB_4795c|M.abscessus_ATCC_199      NHVQGTPPVTAVLDNDGVAFVTAPTGPCLA--GQVVVIDIVDP-PQAPIQ
Mflv_3565|M.gilvum_PYR-GCK          EATSPAELAELARHGLGVAILPQSMARG----GSGLHALRLAPELRGRLV
Mvan_1027|M.vanbaalenii_PYR-1       YVTQVHTMLVLVRSGIGIALVPASAATLHP-EGVVFRTIGAFRERPVELD
MLBr_02041|M.leprae_Br4923          RAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIG
MAV_2789|M.avium_104                ETTNFDEWIESVAADRGIGVIPDVAIRRNVHPGVRFVALRDAPDIPVALA
                                       .            .   :.          .                 

MMAR_4157|M.marinum_M               IGWIADRCLPSSAVAFRETALGCYGHRVSAAGV-----------------
MUL_4020|M.ulcerans_Agy99           IGWIADRCLPSSAVAFRETAFGCYGHRDSAAGV-----------------
Mb2303c|M.bovis_AF2122/97           AIWVGGRTPPAGAIRDLLSHITSRST------------------------
Rv2282c|M.tuberculosis_H37Rv        AIWVGGRTPPAGAIRDLLSHITSRST------------------------
TH_3504|M.thermoresistible__bu      ALWQR---HTLSAIRDRILEG----------------------------L
MSMEG_4331|M.smegmatis_MC2_155      ALWQR---HTHSAIRDMLLADGRRDSHDEIQACVRDEAADDAQRQVLPPQ
MAB_4795c|M.abscessus_ATCC_199      AIWLP---HTQSAIRDALTSG-----------------------------
Mflv_3565|M.gilvum_PYR-GCK          WAWRADGANPAARVLGERARAMAVSPGSGAPAVVPGA-------------
Mvan_1027|M.vanbaalenii_PYR-1       AVWRGD--STNPALLRVLKDVLPQQEWTT---------------------
MLBr_02041|M.leprae_Br4923          LAFRSASGRSASYRQIAKIIGELISTEHHVRLVA----------------
MAV_2789|M.avium_104                FVKRASGPVLRRFIEAAVDAAANQ--------------------------
                                                                                      

MMAR_4157|M.marinum_M               -------------
MUL_4020|M.ulcerans_Agy99           -------------
Mb2303c|M.bovis_AF2122/97           -------------
Rv2282c|M.tuberculosis_H37Rv        -------------
TH_3504|M.thermoresistible__bu      G------------
MSMEG_4331|M.smegmatis_MC2_155      GHDKGGRAGQRRG
MAB_4795c|M.abscessus_ATCC_199      -------------
Mflv_3565|M.gilvum_PYR-GCK          -------------
Mvan_1027|M.vanbaalenii_PYR-1       -------------
MLBr_02041|M.leprae_Br4923          -------------
MAV_2789|M.avium_104                -------------