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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4137 | - | - | 100% (476) | putative [NADP+] succinate-semialdehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3381 | - | 4e-95 | 49.28% (347) | PUTATIVE Succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
| M. thermoresistible (build 8) | TH_4531 | - | 5e-84 | 36.82% (478) | PUTATIVE putative betaine aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 3e-76 | 37.86% (486) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_1858 | - | 1e-114 | 44.61% (473) | succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
| M. tuberculosis H37Rv | Rv0768 | aldA | 3e-76 | 37.86% (486) | aldehyde dehydrogenase NAD dependent AldA |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 5e-69 | 34.63% (462) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4418 | - | 1e-120 | 48.37% (461) | succinate-semialdehyde dehydrogenase |
| M. marinum M | MMAR_3556 | - | 1e-79 | 37.29% (472) | aldehyde dehydrogenase NAD dependent |
| M. avium 104 | MAV_2608 | - | 5e-89 | 40.04% (477) | aldehyde dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_2488 | - | 1e-127 | 48.63% (475) | [NADP+] succinate-semialdehyde dehydrogenase [Mycobacterium |
| M. ulcerans Agy99 | MUL_2789 | - | 4e-79 | 36.86% (472) | gamma-aminobutyraldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4876 | - | 1e-114 | 44.61% (473) | succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1858|M.gilvum_PYR-GCK MDNSAVEALLASVPTGLWIGGEEREGTS--TFDVLDPSDDTVLTSVADAT
Mvan_4876|M.vanbaalenii_PYR-1 MDTS---ALLKSVPTGLWIGGEERQGTS--TFSVLDPSDDEVLATVADAT
MSMEG_2488|M.smegmatis_MC2_155 MTEHEN-RVVSGVQKRLFIDGKWVDATDGATFDVLDPATGEVLCAVADAS
MAB_4418|M.abscessus_ATCC_1997 MHPGTVSTPLSSSSSVVDSALTHQDRHET-TFPVVNPATEEVLADVADLD
TH_4137|M.thermoresistible__bu ----------------MYIDGEWQSAASGKTFASINPANGAVLDSVPDGE
Mb0791|M.bovis_AF2122/97 ---MALWGDG---ISALLIDGKLSDGR-AGTFPTVNPATEEVLGVAADAD
Rv0768|M.tuberculosis_H37Rv ---MALWGDG---ISALLIDGKLSDGR-AGTFPTVNPATEEVLGVAADAD
MMAR_3556|M.marinum_M ---MTTTVS----VAGSWINGAAHSTG-GRQHAVINPATQETIAELALAT
MUL_2789|M.ulcerans_Agy99 ---MTTTVS----VAGSWINGAAHSTG-GRQHAVINPATQETIAELALAT
MAV_2608|M.avium_104 ---MTDTATETLVQFDLLIGGESSSAASGLTYDSVDPFTGRPWARVPNAA
MLBr_02573|M.leprae_Br4923 -----------------------------MSIATINPATGETVKTFTPTT
::* .
Mflv_1858|M.gilvum_PYR-GCK ADDARAALDAACAVQA--EWAGTAPRKRGEILRSVFETITARADDIAALM
Mvan_4876|M.vanbaalenii_PYR-1 ADDARDALDAACAVQG--EWAATPARKRGEILRSVFETITARADDIAALM
MSMEG_2488|M.smegmatis_MC2_155 PQDGRAALDAAVAAQP--EFAALPPRERADMLTGAFELLHERIDDLALLM
MAB_4418|M.abscessus_ATCC_1997 GAAAVAALDNAVAAQR--SWAATTPQQRSDVLMRAYTLMIQRTEDLALLM
TH_4137|M.thermoresistible__bu REDARRAIDAAAAALP--DWRSRTAYERAEVLVEAHRIMLERRDDLAELM
Mb0791|M.bovis_AF2122/97 AEDMGRAIEAARRAFDSTDWS-RNTELRVRCVRQLRDAMQQHVEELRELT
Rv0768|M.tuberculosis_H37Rv AEDMGRAIEAARRAFDSTDWS-RNTELRVRCVRQLRDAMQQHVEELRELT
MMAR_3556|M.marinum_M PADVDRAVVAARRALP--QWAGVTPAERSAVLAKLADLLEQRAPELIAEE
MUL_2789|M.ulcerans_Agy99 PADVDHAVVAARRALP--QWAGVTTAERSAVLAELADLLEQRAPELIAEE
MAV_2608|M.avium_104 AADVDRAVGAARAALNG-PWGALTATARGKLLHRLGEIIAREADQLAELE
MLBr_02573|M.leprae_Br4923 QDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALM
*: * : * : . :
Mflv_1858|M.gilvum_PYR-GCK TLEMGKVLAESK-GEVTYGAEFFRWFAEEAVRIDGRYTAAPAG----TGR
Mvan_4876|M.vanbaalenii_PYR-1 TLEMGKVFAESK-GEVTYGAEFFRWFAEEAVRIEGRYTPAPAG----TGR
MSMEG_2488|M.smegmatis_MC2_155 TLEMGKPLAEAR-GEITYAAEFFRHFAAEAVRIDGGYQTAPAG----GSR
MAB_4418|M.abscessus_ATCC_1997 TLEMGKPLPESR-GEVAYAAEFFRWFAGEAVRLDGSVMLAPDG----QSR
TH_4137|M.thermoresistible__bu TREQGKPLRMAR-TEVGYAADFLLWFAEEAKRVYGEVIPSARA----DQR
Mb0791|M.bovis_AF2122/97 ISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEASPLGIATR
Rv0768|M.tuberculosis_H37Rv ISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEASPLGIATR
MMAR_3556|M.marinum_M VCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPG-QATAEYS---ADHT
MUL_2789|M.ulcerans_Agy99 VCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPG-QATAEYS---ADHT
MAV_2608|M.avium_104 VRDGGK-LVREMVGQMRSLPDYYFYYGGLADKLQGDVIPVDKP----NYF
MLBr_02573|M.leprae_Br4923 TLEMGKTLQSAK-DEAMKCAKGFRYYAEKAETLLADEPAEAAAVG--ASK
: * : . *
Mflv_1858|M.gilvum_PYR-GCK ILVTKQAVGPCYAITPWNFPLAMGTRKMGPAFAAGCTMIVKPAQETPLTM
Mvan_4876|M.vanbaalenii_PYR-1 ILVTKQAVGPCYAITPWNFPLAMGTRKMGPAFAAGCTMIVKPAQETPLTM
MSMEG_2488|M.smegmatis_MC2_155 FLIARQPVGPCLLITPWNFPMAMGTRKLGPAIAAGCTSVIKPAHQTPLSM
MAB_4418|M.abscessus_ATCC_1997 LIVTHRPVGPCLLITPWNFPLAMGTRKIGPALAAGCTCLVKPAEQTPLSM
TH_4137|M.thermoresistible__bu FIVLAQPVGVCAAITPWNYPISMLTRKLAPALAAGCTSVLKPAEQTPLCA
Mb0791|M.bovis_AF2122/97 RTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTPWCA
Rv0768|M.tuberculosis_H37Rv RTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTPWCA
MMAR_3556|M.marinum_M SSIRREAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPSELTPLTT
MUL_2789|M.ulcerans_Agy99 SSIRREAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPSELTPLTT
MAV_2608|M.avium_104 VYTRHEPVGVVGAITPWNSPLLLLTWKLAAGLAAGCTFVVKPSDHTPTST
MLBr_02573|M.leprae_Br4923 ALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCA
..:* : *** * ..: ** . ::* : .*
Mflv_1858|M.gilvum_PYR-GCK LLLAKLMADAG-LPKGVLSVLPTTSPGPVTETLIDDGRLRKLTFTGSTGV
Mvan_4876|M.vanbaalenii_PYR-1 LLLAKLMAEAG-LPKGVLSVLPTSNPGAVTEALINDGRLRKLTFTGSTGV
MSMEG_2488|M.smegmatis_MC2_155 LALMDILSEVG-VPAGAVNCVTAMDAGGVMEPLIRSGLARKLSFTGSTKV
MAB_4418|M.abscessus_ATCC_1997 LALLGILREAG-VPDGVVSVITTADPGATMAPLLADPRVRKLSFTGSTEV
TH_4137|M.thermoresistible__bu VETFKVFADAG-VPAGVVNLVTCSDPEPVADELLGDPRVRKISFTGSTEV
Mb0791|M.bovis_AF2122/97 AALGEIIVEHTDFPPGVVNIVTSSS-HALGALLAKDPRVDMISFTGSTAT
Rv0768|M.tuberculosis_H37Rv AALGEIIVEHTDFPPGVVNIVTSSS-HALGALLAKDPRVDMISFTGSTAT
MMAR_3556|M.marinum_M LTLARLAAEAG-LPDGVLNVVTGLG-ADVGAALAAHPGVDLVTFTGSTAV
MUL_2789|M.ulcerans_Agy99 LTLARLAAEAG-LPDGVLNVVTGLG-ADVGAALAAHPGVDLVTFTGSTAV
MAV_2608|M.avium_104 LAFAKLFAEAG-FPPGVINVVTGWG-PETGAALASHPGVDKVAFTGSTAT
MLBr_02573|M.leprae_Br4923 LYLADVIARGGFPEDCFQTLLISAN---GVEAILRDPRVAAATLTGSEPA
: . : . : ::*** .
Mflv_1858|M.gilvum_PYR-GCK GKALVKQSADKLLRTSMELGGNAPFVVFDDADVDAAVDGAILAKMRNGGE
Mvan_4876|M.vanbaalenii_PYR-1 GKALVKQSADKLLRTSMELGGNAPFIVFDDADVDAAVDGAILAKMRNGGE
MSMEG_2488|M.smegmatis_MC2_155 GRMLLEQCAEKILRTSLELGGNAPLIVFEDADLDEAVEGAILAKMRNMGE
MAB_4418|M.abscessus_ATCC_1997 GRYLLAQCAPTVKRTSMELGGNAPFIVFDDADPEEAAAGALIAKMRNIGQ
TH_4137|M.thermoresistible__bu GRMIASRAGATMKRVSMELGGHAPFLVFPDADPEHAAKGGAAVKFLNTGQ
Mb0791|M.bovis_AF2122/97 GRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMHAGQ
Rv0768|M.tuberculosis_H37Rv GRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMHAGQ
MMAR_3556|M.marinum_M GRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGALINSGQ
MUL_2789|M.ulcerans_Agy99 GRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGAVINSGQ
MAV_2608|M.avium_104 GIHVGKAAIENMTRFSLELGGKSAQVVFADADLDAAANGVIAGVFAATGQ
MLBr_02573|M.leprae_Br4923 GQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQNNGQ
* : . :**** . :*: .** * *:
Mflv_1858|M.gilvum_PYR-GCK ACTAANRIHVANAVREEFTDKFVKRMSEFTLGKGLDEKSTLGPLINAKQV
Mvan_4876|M.vanbaalenii_PYR-1 ACTAANRIHVANAVREEFTEKFVKRMSEFTLGKGLDEKSTLGPLINAKQV
MSMEG_2488|M.smegmatis_MC2_155 ACTAANRLFVHSSVIDEFGRRLAERMAEMPVGRGTEDGVRVGPLIDEAAL
MAB_4418|M.abscessus_ATCC_1997 ACTAANRIYVQRGIADAFTEALTTKLTALRMGPGVEPGVDVGPLIDPDAV
TH_4137|M.thermoresistible__bu ACICPNRFIVHRSIAEPFIATLRARIEKLVPGDGLAAGTTVGPLIDEVAL
Mb0791|M.bovis_AF2122/97 GCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISARQR
Rv0768|M.tuberculosis_H37Rv GCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISARQR
MMAR_3556|M.marinum_M DCTAATRAIVARELYHDFVAGVADVMSTVVIGDPMDPDTDIGPLISLAHR
MUL_2789|M.ulcerans_Agy99 DCTAATRAIVARELCHDFVAGVADVMSTVVIGDPMDPDTDIGPLISLAHR
MAV_2608|M.avium_104 TCLAGSRLLVDRSVADALVEKIVARAATIKLGDPKDPTTEMGPVSNLPQY
MLBr_02573|M.leprae_Br4923 SCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGR
* .* . . . * **:
Mflv_1858|M.gilvum_PYR-GCK ATVTELVSDAVSRGATVAVGGVAPGGP----GNFYPATVLTDVPADARIL
Mvan_4876|M.vanbaalenii_PYR-1 ATVTELVSDAVSRGATVAVGGVAPGGP----GNFYPATVLTDVPADARIL
MSMEG_2488|M.smegmatis_MC2_155 QKVTSLVDDAVKRGATVLTGGSAPSGP----GFFYPPTVLSGVPRDAEMV
MAB_4418|M.abscessus_ATCC_1997 AKADRLVTDARKRGATVRLGGEVPDGT----GYFYPPSVLTDVPDESDMM
TH_4137|M.thermoresistible__bu KKMQRQVDDAVDKGAKLELGGSRLQGPAFDNGHFYAPTILTGVTPDMLIC
Mb0791|M.bovis_AF2122/97 DRVQGYLDLAVAEGGRFACGGARPADREV--GFYIEPTVIAGLTNDARVA
Rv0768|M.tuberculosis_H37Rv DRVQGYLDLAVAEGGRFACGGARPADREV--GFYIEPTVIAGLTNDARVA
MMAR_3556|M.marinum_M DRVADIVAKAPAQGARIVVGG-RIPDLAG--AFYLP-TLLADVGEQSQAY
MUL_2789|M.ulcerans_Agy99 DRVADILAKAPAQGARIVVGG-RIPDLAG--AFYLP-TLLADVGEQSQAY
MAV_2608|M.avium_104 EKVLSHFASAREQGATVAYGG-EPASDLG--GFFVKPTVLTGVDPSMRAV
MLBr_02573|M.leprae_Br4923 AQVEQQVDAAAAAGAVIRCGGKRPDRP----GWFYPPTVITDITKDMALY
. * *. . ** . : ::::.: .
Mflv_1858|M.gilvum_PYR-GCK KEEVFGPVAPIAGFDTEEEGIAAANDTEYGLAAYVYTQSLDRALRVAEGI
Mvan_4876|M.vanbaalenii_PYR-1 KEEVFGPVAPIAGFDTEEEGIAAANDTEYGLAAYVYTQSLDRALRVAENI
MSMEG_2488|M.smegmatis_MC2_155 GQEIFGPVAPLTPFDTEEEAVAAANDTEYGLVSYVFTNDLRRALRVAEAL
MAB_4418|M.abscessus_ATCC_1997 RTEIFAPVAAIATFETEQEVITRANDSEFGLVAYLYTNDTRRGWRVSEQL
TH_4137|M.thermoresistible__bu SEETFGPIAPVMVFDDEDEAIAMANSTEYGLAGYIYTRDISRAIRVGEAL
Mb0791|M.bovis_AF2122/97 REEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIASRL
Rv0768|M.tuberculosis_H37Rv REEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIASRL
MMAR_3556|M.marinum_M REEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRASREI
MUL_2789|M.ulcerans_Agy99 REEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRASREI
MAV_2608|M.avium_104 AEEIFGPVLAVMTFEDEDEAVAAANGTEFGLAAAVWTKDVHRAHRVAAKL
MLBr_02573|M.leprae_Br4923 TDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNI
* *.*: .: :: : ** : :** . : . . : :
Mflv_1858|M.gilvum_PYR-GCK ESGMVGVNRGVISDPAAPFGGIKESGFGREGGTEGIEEYLDTKYIALTK-
Mvan_4876|M.vanbaalenii_PYR-1 ESGMVGVNRGVISDAAAPFGGIKESGFGREGGTEGIEEYLDTKYIALTR-
MSMEG_2488|M.smegmatis_MC2_155 ETGMVGLNQGIVSNPAAPFGGIKESGLGREGGAVGIDEFLETKYVGIKM-
MAB_4418|M.abscessus_ATCC_1997 ETGMVGLNRPVVSTPAAPFGGVKQSGIGREGGFAGIEEFMETKYIGAAV-
TH_4137|M.thermoresistible__bu DFGMIGINDINPTSAAVPFGGIKQSGLGREGARAGIEEYLDTKVLGIAL-
Mb0791|M.bovis_AF2122/97 RVGTVNVNGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLEAKLIATAAN
Rv0768|M.tuberculosis_H37Rv RVGTVNVNGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLEAKLIATAAN
MMAR_3556|M.marinum_M SAGCVWINDHIPIVSEMPHGGVAASGFGKDMSEYSFEEYLTIKHVMSDIT
MUL_2789|M.ulcerans_Agy99 SAGCVWINDHIPIVSEMPHGGVAASGFGNDMSEYSFDEYLTIKHVMSDIT
MAV_2608|M.avium_104 RAGTVWVNAYRVVAPHVPFGGIGYSGIGRENGIDAVKDFTETKAVWVELS
MLBr_02573|M.leprae_Br4923 VAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA--
* : :* . *.** ** *.: . .. :: * :
Mflv_1858|M.gilvum_PYR-GCK ----------------
Mvan_4876|M.vanbaalenii_PYR-1 ----------------
MSMEG_2488|M.smegmatis_MC2_155 ----------------
MAB_4418|M.abscessus_ATCC_1997 ----------------
TH_4137|M.thermoresistible__bu ----------------
Mb0791|M.bovis_AF2122/97 ----------------
Rv0768|M.tuberculosis_H37Rv ----------------
MMAR_3556|M.marinum_M GVAEKPWHRTIFSTRI
MUL_2789|M.ulcerans_Agy99 GVAEKPWHRTIFSTRI
MAV_2608|M.avium_104 GETRDPFTLG------
MLBr_02573|M.leprae_Br4923 ----------------