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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3381 | - | - | 100% (362) | Succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
| M. thermoresistible (build 8) | TH_4137 | - | 3e-95 | 49.28% (347) | PUTATIVE putative [NADP+] succinate-semialdehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3080 | - | 7e-70 | 39.09% (353) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 9e-65 | 40.00% (345) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_1858 | - | 1e-174 | 87.43% (350) | succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
| M. tuberculosis H37Rv | Rv0223c | - | 2e-65 | 37.28% (346) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 2e-62 | 37.61% (351) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4208 | - | 1e-148 | 73.95% (357) | putative succinate-semialdehyde dehydrogenase |
| M. marinum M | MMAR_3556 | - | 3e-76 | 42.90% (338) | aldehyde dehydrogenase NAD dependent |
| M. avium 104 | MAV_2101 | - | 2e-75 | 42.77% (339) | aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5538 | - | 1e-176 | 87.15% (358) | [NADP+] succinate-semialdehyde dehydrogenase [Mycobacterium |
| M. ulcerans Agy99 | MUL_2789 | - | 3e-75 | 42.31% (338) | gamma-aminobutyraldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4876 | - | 1e-176 | 87.78% (360) | succinate-semialdehyde dehydrogenase (NAD(P)(+)) |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1858|M.gilvum_PYR-GCK MDNSAVEALLASVPTGLWIGGEEREGTS--TFDVLDPSDDTVLTSVADAT
Mvan_4876|M.vanbaalenii_PYR-1 MDTS---ALLKSVPTGLWIGGEERQGTS--TFSVLDPSDDEVLATVADAT
MSMEG_5538|M.smegmatis_MC2_155 MRIE---DLISSVPTGLWIGGEEREAAS--TFNVLDPSDDQVITAVADAT
TH_3381|M.thermoresistible__bu --------------------------------------------------
MAB_4208|M.abscessus_ATCC_1997 MTDHS--TLIDAIPTDLWIGGKQVPSSTGTRFPVHNPATGAVLTTVADAA
MMAR_3556|M.marinum_M -------MTTTVSVAGSWING-AAHSTGGRQHAVINPATQETIAELALAT
MUL_2789|M.ulcerans_Agy99 -------MTTTVSVAGSWING-AAHSTGGRQHAVINPATQETIAELALAT
Rv0223c|M.tuberculosis_H37Rv ------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAA
MAV_2101|M.avium_104 ---------------------------MSTTIPVFNPSTEEQIAEVPDSD
Mb0791|M.bovis_AF2122/97 ------MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVAADAD
MLBr_02573|M.leprae_Br4923 -----------------------------MSIATINPATGETVKTFTPTT
Mflv_1858|M.gilvum_PYR-GCK ADDARAALDAACAVQA--EWAGTAPRKRGEILRSVFETITARADDIAALM
Mvan_4876|M.vanbaalenii_PYR-1 ADDARDALDAACAVQG--EWAATPARKRGEILRSVFETITARADDIAALM
MSMEG_5538|M.smegmatis_MC2_155 AEDAIAALDAACAVQD--EWAATPARTRGEILRSVFEKITERADDIAALM
TH_3381|M.thermoresistible__bu -----------------------VVRRRG---------------------
MAB_4208|M.abscessus_ATCC_1997 ASDGAIALDEATAVQR--SWAATAPRERAEILRRAWELVIARRDDFALAM
MMAR_3556|M.marinum_M PADVDRAVVAARRALP--QWAGVTPAERSAVLAKLADLLEQRAPELIAEE
MUL_2789|M.ulcerans_Agy99 PADVDHAVVAARRALP--QWAGVTTAERSAVLAELADLLEQRAPELIAEE
Rv0223c|M.tuberculosis_H37Rv AADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLL
MAV_2101|M.avium_104 QAAVDAAVARARETFESGVWRKAPASHRANVLFRAARIIEERKDELAALE
Mb0791|M.bovis_AF2122/97 AEDMGRAIEAARRAFDSTDWSRN-TELRVRCVRQLRDAMQQHVEELRELT
MLBr_02573|M.leprae_Br4923 QDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALM
*
Mflv_1858|M.gilvum_PYR-GCK TLEMGKVLAESKGEVTYGAEFFRWFAEEAVRIDGRYTAAPAGTG------
Mvan_4876|M.vanbaalenii_PYR-1 TLEMGKVFAESKGEVTYGAEFFRWFAEEAVRIEGRYTPAPAGTG------
MSMEG_5538|M.smegmatis_MC2_155 TLEMGKVLPESKGEVAYGAEFFRWFSEEAVRIDGRYTHAPAGTG------
TH_3381|M.thermoresistible__bu ---------------------------------GPPPRAPAGNG------
MAB_4208|M.abscessus_ATCC_1997 TLEMGKPLAESQGEVAYGGEFLRWFSEEAVRINGRYTSSPTGAG------
MMAR_3556|M.marinum_M VCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPGQATAEYSAD------
MUL_2789|M.ulcerans_Agy99 VCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPGQATAEYSAD------
Rv0223c|M.tuberculosis_H37Rv AAETGQPPTIIETMHWMGSMGAMNYFAGAADKVTWTETRTGSYG------
MAV_2101|M.avium_104 SQDNGMNLTAAGHIIPV-SVDMLKYYAGWVGKIHGESANLVSDGLLGTWE
Mb0791|M.bovis_AF2122/97 ISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEASPLG---I
MLBr_02573|M.leprae_Br4923 TLEMGKTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEAAAVG------
.
Mflv_1858|M.gilvum_PYR-GCK --RILVTKQAVGPCYAITPWNFPLAMGTRKMGPAFAAGCTMIVKPAQETP
Mvan_4876|M.vanbaalenii_PYR-1 --RILVTKQAVGPCYAITPWNFPLAMGTRKMGPAFAAGCTMIVKPAQETP
MSMEG_5538|M.smegmatis_MC2_155 --RILVTKQAVGPCYAITPWNFPLAMGTRKMGPAFAAGCTMIVKPAQETP
TH_3381|M.thermoresistible__bu --RILVTKQAVGPCYAITPWNFPLAMGTRKIGPALAAGCTMIVKPAQETP
MAB_4208|M.abscessus_ATCC_1997 --RILVAKQPIGPTLAITPWNFPLAMGTRKIGPALAAGCTMIVKPAAETP
MMAR_3556|M.marinum_M -HTSSIRREAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPSELTP
MUL_2789|M.ulcerans_Agy99 -HTSSIRREAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPSELTP
Rv0223c|M.tuberculosis_H37Rv --QSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAETP
MAV_2101|M.avium_104 TYHTFTQLEPVGVVGLIIPWNGPFFVAMLKVAPALAAGCSAVLKPAEETP
Mb0791|M.bovis_AF2122/97 ATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTP
MLBr_02573|M.leprae_Br4923 ASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVP
:.:* : .** * **: ** ::* : .*
Mflv_1858|M.gilvum_PYR-GCK LTMLLLAKLMADAG-LPKGVLSVLPTTSPGPVTETLIDDGRLRKLTFTGS
Mvan_4876|M.vanbaalenii_PYR-1 LTMLLLAKLMAEAG-LPKGVLSVLPTSNPGAVTEALINDGRLRKLTFTGS
MSMEG_5538|M.smegmatis_MC2_155 LTMLLLAKLMDEAG-LPKGVLSVLPTSNPRGVTGALIDDGRLRKLTFTGS
TH_3381|M.thermoresistible__bu LTMLLLAKLIDEAG-LPKGVLSVLPTSNPRPLTEALIGDGRLRKLTFTGS
MAB_4208|M.abscessus_ATCC_1997 LTMLLLGQVFADAG-LPAGVLSILPTTNASALTGPLIDDPRLRKLTFTGS
MMAR_3556|M.marinum_M LTTLTLARLAAEAG-LPDGVLNVVTGLGADVG-AALAAHPGVDLVTFTGS
MUL_2789|M.ulcerans_Agy99 LTTLTLARLAAEAG-LPDGVLNVVTGLGADVG-AALAAHPGVDLVTFTGS
Rv0223c|M.tuberculosis_H37Rv LTANALAEVFAEVG-LPEGVLSVVPG-GIETG-QALTSNPDIDMFTFTGS
MAV_2101|M.avium_104 LTALKLEEIFREAG-LPDGVLNVITGYGETTG-AALTAHPDVDKISFTGS
Mb0791|M.bovis_AF2122/97 WCAAALGEIIVEHTDFPPGVVNIVTSSSHALG-ALLAKDPRVDMISFTGS
MLBr_02573|M.leprae_Br4923 QCALYLADVIARGG-FPEDCFQTLLISANGVE--AILRDPRVAAATLTGS
* : :* . .. : : . : ::***
Mflv_1858|M.gilvum_PYR-GCK TGVGKALVKQSADKLLRTSMELGGNAPFVVFDDADVDAAVDGAILAKMRN
Mvan_4876|M.vanbaalenii_PYR-1 TGVGKALVKQSADKLLRTSMELGGNAPFIVFDDADVDAAVDGAILAKMRN
MSMEG_5538|M.smegmatis_MC2_155 TGVGKALVKQSADKLLRTSMELGGNAPFIVFDDADVDAAVDGAILAKMRN
TH_3381|M.thermoresistible__bu TGVGKALAQQASAKLLRTSMELGGNAPFIVFDDADIDAAVDGAMLAKMRN
MAB_4208|M.abscessus_ATCC_1997 TGVGKILLSQCATRVLRSSMELGGNAPFVVFDDADVDAAVDGAMAAKMRN
MMAR_3556|M.marinum_M TAVGRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGALIN
MUL_2789|M.ulcerans_Agy99 TAVGRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGAVIN
Rv0223c|M.tuberculosis_H37Rv SAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMN
MAV_2101|M.avium_104 TEVGRLIVKAAAGNLKRLTLELGGKSPLIMFDDANLDKAIMGAGMGLLAG
Mb0791|M.bovis_AF2122/97 TATGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMH
MLBr_02573|M.leprae_Br4923 EPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQN
.*: : .. :****. . ::: ..:: * .
Mflv_1858|M.gilvum_PYR-GCK GGEACTAANRIHVANAVREEFTDKFVKRMSEFTLGKGLDEKSTLGPLINA
Mvan_4876|M.vanbaalenii_PYR-1 GGEACTAANRIHVANAVREEFTEKFVKRMSEFTLGKGLDEKSTLGPLINA
MSMEG_5538|M.smegmatis_MC2_155 GGEACTAANRFHVANSVREEFTEKLVKRMSEFTLGKGLDPSSTLGPLINS
TH_3381|M.thermoresistible__bu GGEACTAANRFHVANAVREEFTEKLVKRMSEVTLGNGLDGSSTLGPLINA
MAB_4208|M.abscessus_ATCC_1997 IGEACTAANRFHVDNAVRAEFTEKLTARMGALTIGPGDENGVQVGPLITA
MMAR_3556|M.marinum_M SGQDCTAATRAIVARELYHDFVAGVADVMSTVVIGDPMDPDTDIGPLISL
MUL_2789|M.ulcerans_Agy99 SGQDCTAATRAIVARELCHDFVAGVADVMSTVVIGDPMDPDTDIGPLISL
Rv0223c|M.tuberculosis_H37Rv AGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISE
MAV_2101|M.avium_104 SGQNCSCTSRIYVQRGIYDQVVEGLAEFAMMLPMGGSDDPNSVLGPLISE
Mb0791|M.bovis_AF2122/97 AGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISA
MLBr_02573|M.leprae_Br4923 NGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATE
*: * .* . : . . . * : *** .
Mflv_1858|M.gilvum_PYR-GCK KQVATVTELVSDAVSRGATVAVGG--VAPGGPGNFYPATVLTDVPADARI
Mvan_4876|M.vanbaalenii_PYR-1 KQVATVTELVSDAVSRGATVAVGG--VAPGGPGNFYPATVLTDVPADARI
MSMEG_5538|M.smegmatis_MC2_155 KQVATVTELVSDAVSRGATVAVGG--VAPGGPGNFYPATVLADVPADARI
TH_3381|M.thermoresistible__bu QQRDTVVELVTDAVERGATVAVGG--TVPDGPGWFYPATVLTDVSADARI
MAB_4208|M.abscessus_ATCC_1997 KQRASVDELVQDAVSKGAVVTTGG--VVADGEGYFYPPTVLTDVPADARI
MMAR_3556|M.marinum_M AHRDRVADIVAKAPAQGARIVVGG-RIPDLA-GAFYLPTLLADVGEQSQA
MUL_2789|M.ulcerans_Agy99 AHRDRVADILAKAPAQGARIVVGG-RIPDLA-GAFYLPTLLADVGEQSQA
Rv0223c|M.tuberculosis_H37Rv KQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMTI
MAV_2101|M.avium_104 KQRQRVEGIVNDGVAAGAKVITGG-KPMDRK-GYFYEATIITNTTPDMRL
Mb0791|M.bovis_AF2122/97 RQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGLTNDARV
MLBr_02573|M.leprae_Br4923 SGRAQVEQQVDAAAAAGAVIRCGG--KRPDRPGWFYPPTVITDITKDMAL
* : . *. . ** * : .*:::. .
Mflv_1858|M.gilvum_PYR-GCK LKEEVFGPVAPIAGFDTEEEGIAAANDTEYGLAAYVYTQSLDRALRVAEG
Mvan_4876|M.vanbaalenii_PYR-1 LKEEVFGPVAPIAGFDTEEEGIAAANDTEYGLAAYVYTQSLDRALRVAEN
MSMEG_5538|M.smegmatis_MC2_155 LKEEVFGPVAPITGFDTEEEGIAAANDTEYGLAAYIYTQSLDRALRVAET
TH_3381|M.thermoresistible__bu LKEEVFGPVAPIVGFDTEEEGIAAANDTEYGLAAYIYTRSLDRALRVAEA
MAB_4208|M.abscessus_ATCC_1997 LREEVFGPVAAITGFDGEEAGIAAANDTEFGLAAYVYTANLDRALRVSQA
MMAR_3556|M.marinum_M YREEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRASRE
MUL_2789|M.ulcerans_Agy99 YREEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRASRE
Rv0223c|M.tuberculosis_H37Rv AQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQ
MAV_2101|M.avium_104 IREEIFGPVGCVIPFDDEDEVIAAANDTHYGLAGAIWTENLSRAHRVVNE
Mb0791|M.bovis_AF2122/97 AREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIASR
MLBr_02573|M.leprae_Br4923 YTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDN
:*:**** : : : ** : :**.. : . . :
Mflv_1858|M.gilvum_PYR-GCK IESGMVGVNRGVISDPAAPFGGIKESGFGREGGTEGIEEYLDTKYIALTK
Mvan_4876|M.vanbaalenii_PYR-1 IESGMVGVNRGVISDAAAPFGGIKESGFGREGGTEGIEEYLDTKYIALTR
MSMEG_5538|M.smegmatis_MC2_155 IQSGMVGINRGVISDPAAPFGGIKESGFGREGGIEGIEEYLDTKYIALTK
TH_3381|M.thermoresistible__bu IESGMVGVNRGVISDAAAPFGGIKESGFGREGGTEGIEEYLETKYIALT-
MAB_4208|M.abscessus_ATCC_1997 VESGMVGVNRGVISDVAAPFGGIKESGIGREAGSEGIEEYLETKYIALP-
MMAR_3556|M.marinum_M ISAGCVWINDHIPIVSEMPHGGVAASGFGKDMSEYSFEEYLTIKHVMSDI
MUL_2789|M.ulcerans_Agy99 ISAGCVWINDHIPIVSEMPHGGVAASGFGNDMSEYSFDEYLTIKHVMSDI
Rv0223c|M.tuberculosis_H37Rv IRTGTYGIN-WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLPM
MAV_2101|M.avium_104 LRAGQIWVNSALAADPSMPISGHKQSGWGGERGRKGIEAYFNTKAVYIGL
Mb0791|M.bovis_AF2122/97 LRVGTVNVNGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLEAKLIATAA
MLBr_02573|M.leprae_Br4923 IVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA-
: * :* * .* ** * : . .. : * :
Mflv_1858|M.gilvum_PYR-GCK -----------------
Mvan_4876|M.vanbaalenii_PYR-1 -----------------
MSMEG_5538|M.smegmatis_MC2_155 -----------------
TH_3381|M.thermoresistible__bu -----------------
MAB_4208|M.abscessus_ATCC_1997 -----------------
MMAR_3556|M.marinum_M TGVAEKPWHRTIFSTRI
MUL_2789|M.ulcerans_Agy99 TGVAEKPWHRTIFSTRI
Rv0223c|M.tuberculosis_H37Rv GYTVA------------
MAV_2101|M.avium_104 -----------------
Mb0791|M.bovis_AF2122/97 N----------------
MLBr_02573|M.leprae_Br4923 -----------------