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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4531 | - | - | 100% (487) | putative betaine aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3419 | - | e-127 | 50.63% (478) | PUTATIVE putative aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_2957 | - | e-124 | 48.36% (488) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2883c | aldC | 9e-79 | 38.26% (460) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1907 | - | 1e-110 | 46.19% (472) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0223c | - | 2e-85 | 38.53% (475) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 2e-57 | 31.82% (462) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 4e-82 | 39.35% (460) | aldehyde dehydrogenase |
| M. marinum M | MMAR_3965 | - | 1e-81 | 37.53% (485) | NAD-dependent aldehyde dehydrogenase |
| M. avium 104 | MAV_3553 | - | 1e-110 | 45.55% (472) | aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5815 | - | 1e-113 | 45.59% (476) | betaine aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_1122 | - | 2e-78 | 37.01% (481) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0240 | - | 3e-85 | 38.64% (484) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1907|M.gilvum_PYR-GCK ---MVADPVTPIGLLIGTDRLTRTSLAPHPHIYPATGAPNATVALAGADE
MSMEG_5815|M.smegmatis_MC2_155 -MTSVVLPGDPIGSLIGDRRVTASSGGLHAHVYPATGLPNATVALAGAAE
MAV_3553|M.avium_104 MTATASSPPRTGALLIGTERITAASGGSHQHRYPGTGVPNATIPLAGHSE
TH_4531|M.thermoresistible__bu --VTTTENRLVSEIHLAGRRLAEGSAGVYEHVNPATGKVQGEVPLAGPAE
Mb2883c|M.bovis_AF2122/97 -------------------------MSTTQLINPATEEVLASVDHTDANA
Rv0223c|M.tuberculosis_H37Rv ---MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAAD
MUL_1122|M.ulcerans_Agy99 ----MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKVPLAAAAD
MAB_4484|M.abscessus_ATCC_1997 -------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQCPLASPAD
Mvan_0240|M.vanbaalenii_PYR-1 MTQSTTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKVPLASAAD
MMAR_3965|M.marinum_M -MTADSTHRSFHELFIGGRWCKPTIAEPITVISPHSEEPIGRAPAAGPDE
MLBr_02573|M.leprae_Br4923 --------------------------MSIATINPATGETVKTFTPTTQDE
* : :
Mflv_1907|M.gilvum_PYR-GCK VGMAVSAAREAQR--EWITLGVDQRRDKLIDLADVVREHLGELAELNTLD
MSMEG_5815|M.smegmatis_MC2_155 VDAAVSAAWEAHR--EWVAHPADRRRDMLVGLADVVHEHLDELAGLNVHD
MAV_3553|M.avium_104 VDRAVHSAREAQR--EWISYPVDRRRDLLFGLADLLRDHFAELTELNVHD
TH_4531|M.thermoresistible__bu VDEAVAAAQEAFK--EWRKWRPEDRRRLLTRIAERIRAHEDELAVLQARE
Mb2883c|M.bovis_AF2122/97 VDDAVQRARAAQR--RWARLAPAQRAAGLRAFAAAVQAHLDELAALEVAN
Rv0223c|M.tuberculosis_H37Rv VDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAE
MUL_1122|M.ulcerans_Agy99 VDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHFAKLFADE
MAB_4484|M.abscessus_ATCC_1997 VDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEICKAIADE
Mvan_0240|M.vanbaalenii_PYR-1 VDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADELKFLLAAE
MMAR_3965|M.marinum_M VEAAVAAARRAFDYGPWPRLDPDERIRKVEELAAIYASHLDDMADLITAE
MLBr_02573|M.leprae_Br4923 VEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALMTLE
* * * : * . . :
Mflv_1907|M.gilvum_PYR-GCK YGVPISYAGNAVMLDQ---FLRHFAGYVDKPHGSSTPVSGSSDVNLIER-
MSMEG_5815|M.smegmatis_MC2_155 YAVPISNAGTALLLER---FLRHFAGYADKPHGTSSPVSGSFDVNIIER-
MAV_3553|M.avium_104 YGVPISVAGNSVLTER---FVRYYAGYPDKLTGASTPVSGAFDVNIVER-
TH_4531|M.thermoresistible__bu NGLPVS-QGKAVLVPHGAGWFEAAAGWADKLEGAVVPTTPGETVDLTLL-
Mb2883c|M.bovis_AF2122/97 SGHPIVSAEWEAGHVR--DVLAFYAASPERLSGRQIPVAGG--VDVTFN-
Rv0223c|M.tuberculosis_H37Rv TGQPPTIIETMHWMGS-MGAMNYFAG-AADKVTWTETRTGSYGQSIVSR-
MUL_1122|M.ulcerans_Agy99 TGQPPMTVETMHWMGS-IGALNFFAGPAVDQVRWKEIRNGSYGQTIVHR-
MAB_4484|M.abscessus_ATCC_1997 TGAPPMVIETLQWMGG-FGAIQYYAN-AADAVKWKELRNGAYGQTLVTR-
Mvan_0240|M.vanbaalenii_PYR-1 TGQPPTIVDMMQYGAA-MSSFQFYAG-AADKFTWQDIRDGVYGQTLVVR-
MMAR_3965|M.marinum_M MGSPHSFSRLGQAAGA-AGLMQLALA-AGRNFPWVERRQGIRGQAHLRR-
MLBr_02573|M.leprae_Br4923 MGKTLQSAKDEAMKCA--KGFRYYAEKAETLLADEPAEAAAVGASKALAR
. . .
Mflv_1907|M.gilvum_PYR-GCK -EPFGAVGVIAPWNGSLVVAASCVAPALAAGNAVVFKPSELAPLAALRFG
MSMEG_5815|M.smegmatis_MC2_155 -EPYGVVGVIAPWNGALAVAASCVAPALAAGNAVVFKPSELAPLAALRFG
MAV_3553|M.avium_104 -EPYGVVAVIAPWNGPLVVAGAAVAPALAAGNAVIFKPSELASLAPLRFG
TH_4531|M.thermoresistible__bu -EPIGVVAVILTWNAPIGGWGMCVAPPLAAGCCVILKPSELAPFTSSFIA
Mb2883c|M.bovis_AF2122/97 -EPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTPLTTMRLG
Rv0223c|M.tuberculosis_H37Rv -EPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAETPLTANALA
MUL_1122|M.ulcerans_Agy99 -EPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAETPLTANALA
MAB_4484|M.abscessus_ATCC_1997 -EPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAETPLSSFILA
Mvan_0240|M.vanbaalenii_PYR-1 -EPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAETPLSVFAMA
MMAR_3965|M.marinum_M -APVGVVGAIVPWNVPQFLIMPKLIPALIAGCTVIIKPAPETPLDALWLA
MLBr_02573|M.leprae_Br4923 YQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCALYLA
* *.* .: .** . *. ** :.* : .. :.
Mflv_1907|M.gilvum_PYR-GCK ELCLEAGLPPGLVNILPA-AAEGGDALVRHAGIAKIHFTGGGHTARAILR
MSMEG_5815|M.smegmatis_MC2_155 ELCLVAGLPPGLVNILPA-ASDGGDALVRHPGIRKIHFTGGGTTARAVLR
MAV_3553|M.avium_104 ELCLEAGLPPGLVNVLPA-GPEGGEALVRHPGVGKVHFTGGHATAQQVLR
TH_4531|M.thermoresistible__bu RICEEEGMPPGVVTVLPG-GPDAGEALVRHPGVAKVSFTGGGPTGRKIAA
Mb2883c|M.bovis_AF2122/97 ELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMA
Rv0223c|M.tuberculosis_H37Rv EVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGR
MUL_1122|M.ulcerans_Agy99 EVFAEAGLPEGVLSVVPG-GVETGQALTSNPGVDLFTFTGSSAVGKEIGR
MAB_4484|M.abscessus_ATCC_1997 EVFAEAGVPEGVLSVVPG-GAETGRALTNNPDVDVFSFTGSTAVGKEIAE
Mvan_0240|M.vanbaalenii_PYR-1 EMFVEAGLPEGVLSIVPG-GPETGQALTANPNLDKYTFTGSSGVGKEIAK
MMAR_3965|M.marinum_M EMIEQIELPEGVVSVLPG-GPSVGEALVRHPGVDKIAFTGSSATGRRIAA
MLBr_02573|M.leprae_Br4923 DVIARGGFPEDCFQTLLI-SANGVEAILRDPRVAAATLTGSEPAGQAVGA
: . . . : . : .. : :**. ..: :
Mflv_1907|M.gilvum_PYR-GCK AAADNLTPVVTELGGKSANIIFDDADLDIAAVRSAHQGPLMQSGQSCACA
MSMEG_5815|M.smegmatis_MC2_155 AATDNLTPVVTELGGKSANIIFPDADLGRAAALAAHQGPLMQSGQSCACA
MAV_3553|M.avium_104 AASDNVTPVTAELGGKSAYLVFADADLDTAAVIAAHQGPLTQAGQSCACA
TH_4531|M.thermoresistible__bu ACGEQLKPVLLELGGKSANIVFPDADLAKAAETAASV--IFSAGQACTLP
Mb2883c|M.bovis_AF2122/97 GAAAQVKRVTLELGGKSANIVFHDCDLERAATTAPAG-VFDNAGQDCCAR
Rv0223c|M.tuberculosis_H37Rv RAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSG-VMNAGQGCVNQ
MUL_1122|M.ulcerans_Agy99 RAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSG-IMNTGQACVGQ
MAB_4484|M.abscessus_ATCC_1997 IAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSG-LMNAGQGCVNQ
Mvan_0240|M.vanbaalenii_PYR-1 IAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSG-LMNSGQACVGQ
MMAR_3965|M.marinum_M LCGEGLKRVSLELGGKSAAIILDDADIGKTVAGLKTAG-LMNNGQACVAQ
MLBr_02573|M.leprae_Br4923 IAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGR-VQNNGQSCIAA
. :. ****... ::: . *: : . . ** *
Mflv_1907|M.gilvum_PYR-GCK SRILVHEAVYEAFTERFIDVVESARIGDPLDPATVFGPVISAAALDRIVG
MSMEG_5815|M.smegmatis_MC2_155 SRILVHESVYDAFTEQFLAVIGAARVGDPFDPEVNFGPVISAGSLDRLLN
MAV_3553|M.avium_104 SRILVEASVYVSFVEKLVAQVQAATIGDPLRPDVMLGPVITEAAADRILG
TH_4531|M.thermoresistible__bu TRILVHESIYDEFTAMVAGALGQIPLGDPLDPATMMGPVISEAAVERILR
Mb2883c|M.bovis_AF2122/97 SRILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAG
Rv0223c|M.tuberculosis_H37Rv TRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEG
MUL_1122|M.ulcerans_Agy99 TRILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLISEKQRARVEG
MAB_4484|M.abscessus_ATCC_1997 TRVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLITEKQRTRVEG
Mvan_0240|M.vanbaalenii_PYR-1 TRILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLISEKQRDRVEG
MMAR_3965|M.marinum_M TRILVSERRHDEVVDALADMMSALQVGDPADEKTDVGPLVAQRQQRRVRD
MLBr_02573|M.leprae_Br4923 KRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGRAQVEQ
.*.:. : . . * * . .*.: : ::
Mflv_1907|M.gilvum_PYR-GCK VVGEAVDSGSGDLLAGGRRLTEDSLAAGYYLEPTVLGNVDNTSPLAQTET
MSMEG_5815|M.smegmatis_MC2_155 VVHRAVEERAGELLVGGERLVDGALAGGFYMQPTVFGGVDNRSRLAQVET
MAV_3553|M.avium_104 VIERAVAEKAGDLVTGGRRLG-GELASGYFIEPTIFSNVDNRSSLAQTET
TH_4531|M.thermoresistible__bu TVDEATRDNGAELLTGGSRAG-GELASGYYIEPTLLGNVSPTSEVAQNEV
Mb2883c|M.bovis_AF2122/97 YVPDDAPVAFRGTAPAG---------RGFWFPPTVLTPKRG-DRTVTDEI
Rv0223c|M.tuberculosis_H37Rv YIAKGIEEGARLVCGGGRPEG---LDNGFFIQPTVFADVDNKMTIAQEEI
MUL_1122|M.ulcerans_Agy99 YIAKGIEEGARLVSGGGRPES---LDNGFFVQPTVFADVDNKMTIAQEEI
MAB_4484|M.abscessus_ATCC_1997 YIAKGIAEGARLAYGGKRPEG---LDGGYFVQPTIFADVDNSMTIAQEEI
Mvan_0240|M.vanbaalenii_PYR-1 YIKKGIEEGARVVTGGGRPEG---LDSGWYVQPTVFADVDNSMTIAQEEI
MMAR_3965|M.marinum_M YIRSGQQEGARIVLGG-QDSP---QDRGWYVRPTLFTDATNDMCIAREEI
MLBr_02573|M.leprae_Br4923 QVDAAAAAGAVIRCGGKRPDR-----PGWFYPPTVITDITKDMALYTDEV
: . *:: **:: *
Mflv_1907|M.gilvum_PYR-GCK FGPVVSLIPFADDDGAVRIANDTPYGLNAFVHTRDLTRAHTVARRLQSGS
MSMEG_5815|M.smegmatis_MC2_155 FGPVVSLIRFVDDDEAVRLANDTPYGLNAFVHTADLTRAHTVSRQLEAGS
MAV_3553|M.avium_104 FGPVASVMPFADEAQAVSLANDSRYGLNAFVATANLERAHRVARRLQAGS
TH_4531|M.thermoresistible__bu FGPVTAAIRFSDEEEAVAIANGTPYGLAGYVHTRDVSRVLRLASALEAGT
Mb2883c|M.bovis_AF2122/97 FGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVARAVESGN
Rv0223c|M.tuberculosis_H37Rv FGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQIRTGT
MUL_1122|M.ulcerans_Agy99 FGPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEISEKIRTGT
MAB_4484|M.abscessus_ATCC_1997 FGPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAAQIRTGT
Mvan_0240|M.vanbaalenii_PYR-1 FGPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIARRIRTGT
MMAR_3965|M.marinum_M FGPVLTVLTYRDEQDAIRIANDSDYGLAGSVWTADTAHGLEIAAAVRTGT
MLBr_02573|M.leprae_Br4923 FGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNIVAGQ
**** *: :** : :** . * : . . : :*
Mflv_1907|M.gilvum_PYR-GCK VWIN-QGSRISPQGPYGGYKQSGSGRTGGLEGLREFQQVKNIRIG-----
MSMEG_5815|M.smegmatis_MC2_155 VWVN-QFSQISPQGPYGGYKQSGSGRTGGLDGLHEFQQIKNIRIG-----
MAV_3553|M.avium_104 VWVN-RHSDIEPQGPYGGYKQSGFGRTGGVEGLHEFLQVKNIRIG-----
TH_4531|M.thermoresistible__bu VAFNGAGAPAGPGAPFGGYKESGYGREGGKLGVLEFVQHKTVSVA-----
Mb2883c|M.bovis_AF2122/97 LSVN-SHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIA-----
Rv0223c|M.tuberculosis_H37Rv YGIN--WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLP-----
MUL_1122|M.ulcerans_Agy99 YAIN--WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMP-----
MAB_4484|M.abscessus_ATCC_1997 YGIN--WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVLLP-----
Mvan_0240|M.vanbaalenii_PYR-1 YAVN--MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSILLP-----
MMAR_3965|M.marinum_M YGIN--MYTLDISAPFGGFKQSGIGREFGPEGLAEYVELQTVLCSGKMPP
MLBr_02573|M.leprae_Br4923 VFIN-GMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA-----
.* *:** *.** ** . . : : :.:
Mflv_1907|M.gilvum_PYR-GCK -IG------
MSMEG_5815|M.smegmatis_MC2_155 -MG------
MAV_3553|M.avium_104 -MS------
TH_4531|M.thermoresistible__bu -LS------
Mb2883c|M.bovis_AF2122/97 -VGEEM---
Rv0223c|M.tuberculosis_H37Rv -MGYTVA--
MUL_1122|M.ulcerans_Agy99 -MGYTLES-
MAB_4484|M.abscessus_ATCC_1997 -MGYTLESI
Mvan_0240|M.vanbaalenii_PYR-1 -FGYTPAT-
MMAR_3965|M.marinum_M LRGFEEPAG
MLBr_02573|M.leprae_Br4923 ---------