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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3821 | - | - | 100% (491) | putative adenylate-forming enzyme |
| M. thermoresistible (build 8) | TH_4579 | - | 4e-64 | 34.86% (479) | PUTATIVE putative cyclohexanecarboxylate-CoA ligase |
| M. thermoresistible (build 8) | TH_3067 | - | 7e-50 | 31.36% (507) | PUTATIVE AMP-binding enzyme, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2533c | fadD35 | 6e-43 | 29.12% (491) | AMP-binding domain protein |
| M. gilvum PYR-GCK | Mflv_1784 | - | 2e-48 | 33.07% (499) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2505c | fadD35 | 7e-43 | 29.12% (491) | AMP-binding domain protein |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 3e-35 | 26.76% (441) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4377c | - | 2e-47 | 30.84% (509) | AMP-binding domain protein |
| M. marinum M | MMAR_2616 | - | 1e-45 | 31.72% (476) | hypothetical protein MMAR_2616 |
| M. avium 104 | MAV_2995 | - | 5e-52 | 32.76% (467) | adenylate-forming enzyme |
| M. smegmatis MC2 155 | MSMEG_4112 | - | 1e-45 | 30.16% (514) | cyclohexanecarboxylate-CoA ligase |
| M. ulcerans Agy99 | MUL_3145 | - | 5e-46 | 32.05% (468) | hypothetical protein MUL_3145 |
| M. vanbaalenii PYR-1 | Mvan_4966 | - | 8e-50 | 31.54% (501) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2533c|M.bovis_AF2122/97 --------------------MAAAEVVDPNRLSYDRGPSAPSLLESTIGA
Rv2505c|M.tuberculosis_H37Rv --------------------MAAAEVVDPNRLSYDRGPSAPSLLESTIGA
MAB_4377c|M.abscessus_ATCC_199 ------------------------------MKAYDAGATLSPIIEETIGE
MMAR_2616|M.marinum_M ---------------MAVGRRDMAGSPAFSTQEAIRYHAAGWWSDSTLSD
MUL_3145|M.ulcerans_Agy99 --------------------------------------------------
MAV_2995|M.avium_104 --------------MMSAGGLHTESSPAFSDEDVARFRAAGWWCDSTLSD
Mflv_1784|M.gilvum_PYR-GCK -------------------------------------------MTGTLVE
Mvan_4966|M.vanbaalenii_PYR-1 -------------------------------------------MT-TLAD
TH_3821|M.thermoresistible__bu --------------------------------------------------
MSMEG_4112|M.smegmatis_MC2_155 ---------MTAPTERRLANVLNGQYTPIDDDTAANWRAAGWWENRSIRS
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
Mb2533c|M.bovis_AF2122/97 NLAATAARYGHREALVDMVA---RRRFNYSELLTDVHRLATGLVRAGIGP
Rv2505c|M.tuberculosis_H37Rv NLAATAARYGHREALVDMVA---RRRFNYSELLTDVHRLATGLVRAGIGP
MAB_4377c|M.abscessus_ATCC_199 NFERIARAHPDVGALVDVSG---DRRWTYRELDAEINRVARGLMSLGVAA
MMAR_2616|M.marinum_M AVRRNAECSPHHAAYIDYP----ASLLTWSEFDCAATNLAEQLAGAGVLP
MUL_3145|M.ulcerans_Agy99 -----------------------------------------------MLP
MAV_2995|M.avium_104 AVRRNAQRTPERPAYIDHG----GRTFTWHEFDCAASNLAETLAGLGVGP
Mflv_1784|M.gilvum_PYR-GCK ALRDAARDTPDRVLVRDD-----AVALTCAELLSAATGLAHALTRR-MPA
Mvan_4966|M.vanbaalenii_PYR-1 ALRDAARDTPDRILLRDD-----EASLSSAELLSAATNLAHALVRR-MPV
TH_3821|M.thermoresistible__bu ----MLEADPDAVALIRG-----DQRWSREQLWELSGRAVAKLRSLGAEP
MSMEG_4112|M.smegmatis_MC2_155 LLADAAQAHPDRIALVGRRADGGRVARTYQEFDRNANQVASVLASLGVRP
MLBr_02546|M.leprae_Br4923 LPAMPARRSPHRAALIDE-----EGTLTYKELDRAAHALANGLIAKGVRG
Mb2533c|M.bovis_AF2122/97 GDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVA
Rv2505c|M.tuberculosis_H37Rv GDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVA
MAB_4377c|M.abscessus_ATCC_199 GDRVGIWAPNCAEWVLVQYATAKIGAILVNINPAYRTHELAYALNQSGVR
MMAR_2616|M.marinum_M GDRVAVWHGDCAALHALFIAIERCGAVVVGIGARAGIREATQILRAAQVK
MUL_3145|M.ulcerans_Agy99 GDRVAVWHGDCAALHALFIAIERCGAVVVGIGARAGVREATQILRAAQVK
MAV_2995|M.avium_104 GDRVAVWHGDCAAIHVLFVAIERRGAVIVGIGERAGAREAGAILRNAQPK
Mflv_1784|M.gilvum_PYR-GCK GSVVSFTVPNWHEAAIIYLGATLAGMVVNPILPSLRERELSFILDDADSR
Mvan_4966|M.vanbaalenii_PYR-1 GSVVSFAVPNWHEAAVIYLGATLAGMVVNPILPSLRERELSFILADAGSR
TH_3821|M.thermoresistible__bu GDAVVAHYDTGAEEMAIALAASRLGCVFMPIPRRLGARELNYVVGLADPV
MSMEG_4112|M.smegmatis_MC2_155 DDAVVVMLPNWVEYPEFLFGINELGAIYAGIPVAYGDQQAAAILRRSRAR
MLBr_02546|M.leprae_Br4923 GDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAK
.. : . * : :
Mb2533c|M.bovis_AF2122/97 MVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAG--AEPDL
Rv2505c|M.tuberculosis_H37Rv MVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAG--AEPDL
MAB_4377c|M.abscessus_ATCC_199 TLICAKAFKSSDYVAMASQVMPDAPGLRDVVFIGTSDWTELVAGAERVTE
MMAR_2616|M.marinum_M LLVSDAPR-----SAAATEVSAQLPVPSGVLVREGKTLRFDGKPVPVAPE
MUL_3145|M.ulcerans_Agy99 LLVSDAPR-----SAAATEVSAQLPVPSGVLVREGKTLRFDGKPVPVAPE
MAV_2995|M.avium_104 ILLSDQPR-----SKPAAEVAGELRIPALVLT----------QPLDTEPR
Mflv_1784|M.gilvum_PYR-GCK MIFVPESFGGHDYAAMLDRVAPGLPSPPEVVVVRGE-GRVTLADLLAEPA
Mvan_4966|M.vanbaalenii_PYR-1 AIFIPQTFGGHDYAAMLDRVVAGLPSPPEVVVVRGEPRRPALTDLVSEPR
TH_3821|M.thermoresistible__bu LVAVQDRD---------HVGVVENPGRARVLTLADS-----LAPTGAEVD
MSMEG_4112|M.smegmatis_MC2_155 VLVIPRRWRGNNILEQSRRLRDQIPTLQQVIVLDDDGTDLRDGESLWSDH
MLBr_02546|M.leprae_Br4923 VIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSS
:
Mb2533c|M.bovis_AF2122/97 P---ALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGE
Rv2505c|M.tuberculosis_H37Rv P---ALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGE
MAB_4377c|M.abscessus_ATCC_199 T---ALRARMSQLSNTDPINIQYTSGTTGYPKGATLSHRNVLNNGFFVAE
MMAR_2616|M.marinum_M NGLESELGNERRLGPDDVFLINSTSGTTGAPKCVVHTQNRWHYFHQHAVA
MUL_3145|M.ulcerans_Agy99 NGLESELGNERRLGPDDVFLINSTSGTTGAPKCVVHTQNRWHYFHQHAVA
MAV_2995|M.avium_104 -----AFDRDCQLGPDDVFLINSTSGTTGLPKCVVHTQNRWYYFHQKAVA
Mflv_1784|M.gilvum_PYR-GCK D------GVLPAPRPTDTRMILYTSGTTGRPKGVLHTHESLAALIAQLGR
Mvan_4966|M.vanbaalenii_PYR-1 D------GTLPDLDPAATRMILYTSGTTGRPKGVLHSHKSLGALIAQLGR
TH_3821|M.thermoresistible__bu P---------YRWRPGEAALVGFTSGSTGHPKGVMHGVPAMEWVADLIVE
MSMEG_4112|M.smegmatis_MC2_155 AH--VAARQFPPPDPGQICYLGFTSGTTGEPKGAMHSHNTLIYSARRQAE
MLBr_02546|M.leprae_Br4923 S-------APAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILS
: ***:*. ** .
Mb2533c|M.bovis_AF2122/97 LL---GYTAQDRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAPGFDPAA
Rv2505c|M.tuberculosis_H37Rv LL---GYTAQDRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAPGFDPAA
MAB_4377c|M.abscessus_ATCC_199 SI---QLQAGDRLCIPVPFYHCFGMVMGNLGCTTHGATIVMPAPGFDPGR
MMAR_2616|M.marinum_M NG---MLTPQDVVLPVIPMPFGFGIWTSHTTPIYLGASAVILDR-FTTLA
MUL_3145|M.ulcerans_Agy99 NG---MLTPQDVVLPVIPMPFGFGIWTSHTTPIYLGASAVILDR-FTTLA
MAV_2995|M.avium_104 NG---MLTPDDVFLPVIPTPFGFGIWTSHTTPIHLGATAVILDR-FTPAA
Mflv_1784|M.gilvum_PYR-GCK FW---RIDRGDTFLVPSPIAHIGGSIYAFECPLLLGTEAVLMQR-WDPDA
Mvan_4966|M.vanbaalenii_PYR-1 YW---RIDPGDTFLVPSPIAHIGGSIYAFECPLLLGTQAVLMQR-WDPDA
TH_3821|M.thermoresistible__bu RG---SLRPGEPICVTGAGAGAPGFTFYTYLGLTRGLPIVKSEK-WDPKR
MSMEG_4112|M.smegmatis_MC2_155 HIGTEAFGEPVVNLVASPMGHHTGYVWGGVFTVMLAGTAVHVDR-WDPTW
MLBr_02546|M.leprae_Br4923 KVP---FRAHEVTLLPAPMFHALGYLH-ATLAMFLGSTLVLRRR-FKPAT
. * . * : .
Mb2533c|M.bovis_AF2122/97 TLRAVQDERCTSLYGVPTMFIAELGLPDFTD--YELGSLRTGIMAGAACP
Rv2505c|M.tuberculosis_H37Rv TLRAVQDERCTSLYGVPTMFIAELGLPDFTD--YELGSLRTGIMAGAACP
MAB_4377c|M.abscessus_ATCC_199 TLEAIERERCVGVYGVPTMFIAMLADPGFAH--RDLSTLRTGIMAGSVCP
MMAR_2616|M.marinum_M ACEAIARHRVTVLCCVSTQLTMLMADHWCRA--YDLSSLRVVFAGGEALP
MUL_3145|M.ulcerans_Agy99 ACEAIARHRVTVLCCVSTQLTMLMADHWCRA--YDLSSLRVVFAGGEALP
MAV_2995|M.avium_104 TCEAIARHGVTVLCCVSTQLTMLMADPASRR--HDLSSLRIVYTGGEALP
Mflv_1784|M.gilvum_PYR-GCK AVGLMLEHRVTHMAGATPFLVGLLAAAQRAG--TRLPDLKVFICGGASVP
Mvan_4966|M.vanbaalenii_PYR-1 AVALMLRHRCTHMAGATPFLDGLLAAAERAG--TRLPDLKVFICGGASVP
TH_3821|M.thermoresistible__bu VLELMARERCVWSTMVPTMLHMLMTAQRDSGRAYDLSAMRTVSMGGAPMS
MSMEG_4112|M.smegmatis_MC2_155 GAQVVREEGVTTFFGAPTFLQDIIRTELAGD---PACPLRCMVVAGAPVP
MLBr_02546|M.leprae_Br4923 VLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLG
: . . .. : : :: .*
Mb2533c|M.bovis_AF2122/97 VEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP
Rv2505c|M.tuberculosis_H37Rv VEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP
MAB_4377c|M.abscessus_ATCC_199 VEVMKRCIDEMHMAGVAIAYGMTETSPVSCQTLFDDDLDRRTATVGRAHP
MMAR_2616|M.marinum_M -YRRATEFEDLTGAAILQFYGSNETG-LLSATTLRDSRERRLRTGGRVVP
MUL_3145|M.ulcerans_Agy99 -YRRATEFEDLTGAAILQFYGSNETG-LLSATTLRDSRERRLRTGGRVVP
MAV_2995|M.avium_104 -YRPAAEFEELTGATILQFYGSNETG-MLSATTVHDPRDRRLGTAGRVVP
Mflv_1784|M.gilvum_PYR-GCK PTLIRSAAAYFDKAAVSRVYGSTEVP-VTTVGALDD-IDRAADTDGRPG-
Mvan_4966|M.vanbaalenii_PYR-1 PSLIRRAADYFDKAAVSRVYGSTEVP-VTTVGSLDD-VDRAADTDGRPG-
TH_3821|M.thermoresistible__bu EEFISEARELMTFEPLR-VYAMAECM-MHSHSRADDPIEIRNGMDGRPGP
MSMEG_4112|M.smegmatis_MC2_155 RNLPAQAAEALG-AYVAPAWGMTECS--ILTSCTPDEPDAILRTDGSVFA
MLBr_02546|M.leprae_Br4923 AELATRALEELG-PVIYNMYGSTEIA--FATIAGPKDLQINSATVGPVVK
: : :. * . : *
Mb2533c|M.bovis_AF2122/97 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGW
Rv2505c|M.tuberculosis_H37Rv HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGW
MAB_4377c|M.abscessus_ATCC_199 HIEIKIVDPNSGETVQRGQSGELCTRGYSVMLGYWNDEAHTREVLDTDGW
MMAR_2616|M.marinum_M EMSVRLFDGDRDVTESGR--GQPACRGPATSLGYLG-GTDHEKLFTRDGW
MUL_3145|M.ulcerans_Agy99 EMSVRLFDGDRDVTASGR--GQPGCRGPATSLGYLG-GTDHEKLFTRDGW
MAV_2995|M.avium_104 EMAVRLFDGDTDVTATGR--GQPACRGPATSLGYLG-GTDHDKLFTRDGW
Mflv_1784|M.gilvum_PYR-GCK IAEVRIVDG------------EIRARGPQMFTGYLH-PEDDRESFDDAGY
Mvan_4966|M.vanbaalenii_PYR-1 IADVTLVDG------------EIRARGPQMLTGYLH-PEDNSESFDAEGF
TH_3821|M.thermoresistible__bu GAEIATYDSEGRRLPTGET-GEIGMRGPSLMLGYLG-DAPGSLPLTSDGF
MSMEG_4112|M.smegmatis_MC2_155 GSEVKIVDDTGAAVAAG-VVGDLLMRGPGVVYGYYDRPDATRDAYLPGLW
MLBr_02546|M.leprae_Br4923 GVKVKILDDSGKEVPRGQ-VGRIFVGNAFPFEGYTG----GGGKQIIDGL
: * . **
Mb2533c|M.bovis_AF2122/97 MHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDG
Rv2505c|M.tuberculosis_H37Rv MHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDG
MAB_4377c|M.abscessus_ATCC_199 MHTGDLAVMRDDGYCTIIGRLKDMVIRGGENIYPREIEEFLLTHPDIEDV
MMAR_2616|M.marinum_M MRMGDICEIDPDGYLTVTGRTSDFILRGGKNISAGQVEDAALTHPAVAIA
MUL_3145|M.ulcerans_Agy99 MRMGDICEIDPDGYLTVTGRTSDFILRGGKNISAGQVEDAALTHPAVAIA
MAV_2995|M.avium_104 MRMGDICEIDADGYLRVTGRTSDFILRGGKNISASQVEDAAMTHPAVAIA
Mflv_1784|M.gilvum_PYR-GCK FRTGDLGRFTEDNHLVVTGRAKDIIIRNGENISPKEVEDILVTHPRIAEI
Mvan_4966|M.vanbaalenii_PYR-1 FRTGDLGHLTDDGYLVVTGRAKDLIIRNGENISPKEVEDILVTHPQIAEI
TH_3821|M.thermoresistible__bu FLSGDLGRVEDNGCIKVVGRLKDMIIRGGYNIDPGEVEELLRAHPEVRDV
MSMEG_4112|M.smegmatis_MC2_155 FKTGDRADVDENGWLRLRGRSKDIIIRGGENIPVTDVESAIFDHPDVLNA
MLBr_02546|M.leprae_Br4923 LSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEA
: ** . . : ** .:::: .* *: ::*. ** :
Mb2533c|M.bovis_AF2122/97 HVIGVPDAKYGEELMAVVKLR-------NDAPELTIERLREYCMGR-IAR
Rv2505c|M.tuberculosis_H37Rv HVIGVPDAKYGEELMAVVKLR-------NDAPELTIERLREYCMGR-IAR
MAB_4377c|M.abscessus_ATCC_199 HVVGVPDEKYGEELCAWVRMR-------PDRVVIDAVAIRAFASGR-LAH
MMAR_2616|M.marinum_M AAVSMPDPVFGEKVCLYVELA--------DSQRLDRTELVEHLLALGYSK
MUL_3145|M.ulcerans_Agy99 AAVSMPDPVFGEKVCLYVELA--------DSQRLDRTELVEHLLALGYSK
MAV_2995|M.avium_104 AAVAMPDPVFGEKVCLYAELAGPATDPATDPATLDLADLTEHLLAQGFSK
Mflv_1784|M.gilvum_PYR-GCK AVVGIPDPRTGERACAALVTT--------EDPPPDIAELKDFLTDRGVAR
Mvan_4966|M.vanbaalenii_PYR-1 AIVGIPDLRTGERACAVIVAA--------DSAAPDVAEIRDFLVARGVAK
TH_3821|M.thermoresistible__bu AIVGYPDPVYGERACAVLWTDG---------VVLGLSDIAEFLLERNLSK
MSMEG_4112|M.smegmatis_MC2_155 AVIGLPDERLGERVCAVLVTKS-------GCPELTVDTLGEYLLGQGLSK
MLBr_02546|M.leprae_Br4923 TAIGVDDKEWGARLRAFVVKK--------QDATIDEDAIKAYVRDH-LAR
:. * * . : . ::
Mb2533c|M.bovis_AF2122/97 FKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ-------
Rv2505c|M.tuberculosis_H37Rv FKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ-------
MAB_4377c|M.abscessus_ATCC_199 YKIPRYVHVVESFPMTVTGKVRKIEMRQQTIQIFGLPEPGRTDEQ
MMAR_2616|M.marinum_M ELLPERLVVVDELPRSSGGKIAKGQLRDDIRARMEAEHERS----
MUL_3145|M.ulcerans_Agy99 ELLPERLVVVDELPRSSGGKIAKGQLRDDIRARMEAEHERS----
MAV_2995|M.avium_104 ELLPERLVVVDELPRSSGGKVAKGRLREDIRARMEAGDERS----
Mflv_1784|M.gilvum_PYR-GCK FKVPEQIHVVGALPKNDAGKVLKHVLKAELTKES-----------
Mvan_4966|M.vanbaalenii_PYR-1 FKAPERVVVVDALPKNDAGKVLKHAIRAVLLEKPREGEP------
TH_3821|M.thermoresistible__bu DKIPEMVVCRDELPQSPDGKILKGQLRAEIAALVATRSG------
MSMEG_4112|M.smegmatis_MC2_155 HYLPEKVVHLDELPMTPSGKIQKFKLREQYS--------------
MLBr_02546|M.leprae_Br4923 YKVPREVIFLEELPRNPTGKVLKRELRDFEVH-------------
*. : :* . **: * ::