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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3067 | - | - | 100% (545) | AMP-binding enzyme, putative |
| M. thermoresistible (build 8) | TH_2816 | - | 9e-67 | 34.54% (527) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3874 | - | 1e-63 | 39.90% (411) | PUTATIVE AMP-binding enzyme, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3116 | fadD13 | 3e-50 | 31.84% (512) | chain-fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_1784 | - | 0.0 | 71.12% (509) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv3089 | fadD13 | 3e-50 | 31.84% (512) | chain-fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_01051 | xclC | 1e-40 | 30.78% (497) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2247c | - | 5e-51 | 31.60% (538) | bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase |
| M. marinum M | MMAR_0303 | - | 0.0 | 66.54% (526) | acyl-CoA synthetase |
| M. avium 104 | MAV_5212 | - | 0.0 | 71.10% (526) | AMP-binding enzyme, putative |
| M. smegmatis MC2 155 | MSMEG_5631 | - | 0.0 | 71.32% (523) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_3641 | mbtA | 1e-49 | 30.50% (541) | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP |
| M. vanbaalenii PYR-1 | Mvan_4966 | - | 0.0 | 72.33% (506) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1784|M.gilvum_PYR-GCK --------------------------------------MTGTLVEALRDA
Mvan_4966|M.vanbaalenii_PYR-1 --------------------------------------MT-TLADALRDA
TH_3067|M.thermoresistible__bu ---------MTETPGAGYRTDRPGHAERAAQAYARGLWVPTTLAEALAEA
MSMEG_5631|M.smegmatis_MC2_155 --------------------------MRAEDAYERGLWVRTTLADTLAEA
MAV_5212|M.avium_104 -----------------MTARAAPDTAQTSLAYRRGWWVRSTLADAARAA
MMAR_0303|M.marinum_M -----MGGPKVPQRRLIDGRWVRWDADRAAGAYAHRWWVRRTLADALREA
MAB_2247c|M.abscessus_ATCC_199 MTQPRSTTTASSAATPALDGFVPFPSVRADEYRRAGYWTGNTVESLLRVS
MUL_3641|M.ulcerans_Agy99 -----------------MAGFIPYPPERVASYRAAGYWTGRSIGSLLRQA
Mb3116|M.bovis_AF2122/97 ---------------------------------------MKNIGWMLRQR
Rv3089|M.tuberculosis_H37Rv ---------------------------------------MKNIGWMLRQR
MLBr_01051|M.leprae_Br4923 -----------------------------------------------MLL
Mflv_1784|M.gilvum_PYR-GCK ARDTPDRVLVRD--DAVALTCAELLSAATGLAHALTRR-MPAGSVVSFTV
Mvan_4966|M.vanbaalenii_PYR-1 ARDTPDRILLRD--DEASLSSAELLSAATNLAHALVRR-MPVGSVVSFAV
TH_3067|M.thermoresistible__bu ARTTPDRTVLVD--GAVRLDCRSLHARATALAGALLRR-IPAGAVVSFML
MSMEG_5631|M.smegmatis_MC2_155 ARDTPQRVLLID--GDVRLTCAELHSRAKALAHEMAAR-MPAGSVVSFML
MAV_5212|M.avium_104 AQRTPERIALVD--NEVRLNCATLYAQAGELAAALLAR-IPAGSVVSFML
MMAR_0303|M.marinum_M AQSTPQRVALVD--ADRQLDCQELHRQAMALAQHLRSR-MPAGSVVSFML
MAB_2247c|M.abscessus_ATCC_199 AARRPCHPAVID--EHRALSYRELDEAADNAAHAFLRLGIAPGDRVLLQL
MUL_3641|M.ulcerans_Agy99 AARWPDRVGVVD--AGASHTFCELDKLADRVAAGFVSLGIAPGDRVLLQL
Mb3116|M.bovis_AF2122/97 ATVSPRLQAYVEPSTDVRMTYAQMNALANRCADVLTALGIAKGDRVALLM
Rv3089|M.tuberculosis_H37Rv ATVSPRLQAYVEPSTDVRMTYAQMNALANRCADVLTALGIAKGDRVALLM
MLBr_01051|M.leprae_Br4923 ASLNPSVVTATDIADAVCVDGVVLSRSGLVGAATSVAERVGGARLVAVLA
* * : : . * : . * .
Mflv_1784|M.gilvum_PYR-GCK PNWHEAAIIYLGATLAGMVVNPILPSLRERELSFILDDADSRMIFVPESF
Mvan_4966|M.vanbaalenii_PYR-1 PNWHEAAVIYLGATLAGMVVNPILPSLRERELSFILADAGSRAIFIPQTF
TH_3067|M.thermoresistible__bu PNWHEAAVIYLGATLAGMVVNPILPSLRDRELRFILDDADSRMIFIPETF
MSMEG_5631|M.smegmatis_MC2_155 PNWHEAAIVYLASTLAGMVINPILPSLRDHELRFILDDAASRMIFIPGEF
MAV_5212|M.avium_104 PNWHEAAVIYLAATLAGMVVNPILPSLRDHDLRFVLEDAGAAMVFVPHRY
MMAR_0303|M.marinum_M PNWHEAAVIYLASTLAAMVANPVLPSLREHELRFILEDAGSRMIFAPADF
MAB_2247c|M.abscessus_ATCC_199 PNRASFAVALFGLMRAGAIPVMCLPGHRAAELSHFIEVADAVGLVIPDSA
MUL_3641|M.ulcerans_Agy99 PNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHHFAEVSGAVGLIVAQHA
Mb3116|M.bovis_AF2122/97 PNSVEFCCLFYGAAKLGAVAVPINTRLAAPEVSFILSDSGSKVVIYGAPS
Rv3089|M.tuberculosis_H37Rv PNSVEFCCLFYGAAKLGAVAVPINTRLAAPEVSFILSDSGSKVVIYGAPS
MLBr_01051|M.leprae_Br4923 TPTASTVLAITGCLIAGVPVVPVPADIGVVERRHMLTDSGAQAWLGPGPS
. . . . : .. : : .
Mflv_1784|M.gilvum_PYR-GCK GGHDYAAMLDRVAPGLPSPPEVVVVRGE------GRVTLADLLAEPADG-
Mvan_4966|M.vanbaalenii_PYR-1 GGHDYAAMLDRVVAGLPSPPEVVVVRGEP-----RRPALTDLVSEPRDG-
TH_3067|M.thermoresistible__bu GNHDYAAMLDRVTAELPNPPQVVVVRGAVR---PDRVSYDALLSGPVDRP
MSMEG_5631|M.smegmatis_MC2_155 GQHDYAAMLQRVCAHLPTPPQVVVVRGEP-----GPHTAFTALGAPGGD-
MAV_5212|M.avium_104 GGHDYPAMLDRVTAAMSAAPQVVVLRGPDTGRTGRHTPYRCMLGGPPGG-
MMAR_0303|M.marinum_M RGHDYTSMLRRVAAQLPSRPEVIEVRGQCP---DGVSTFQSLLVGRETAA
MAB_2247c|M.abscessus_ATCC_199 GGFDYRALAVALSQRHPRLRTVVVEGDAGP-----FASWTSLLKSVEPQG
MUL_3641|M.ulcerans_Agy99 GGFDYRSMAERLVAAHPQLRHVIIDGESGP-----FLPWSSLSEGATPD-
Mb3116|M.bovis_AF2122/97 -----APVIDAIRAQADPPGTVTDWIGADS--------LAERLRSAAADE
Rv3089|M.tuberculosis_H37Rv -----APVIDAIRAQADPPGTVTDWIGADS--------LAERLRSAAADE
MLBr_01051|M.leprae_Br4923 --------ADSAPDGLPHIPVQLDARSWNR--------------------
Mflv_1784|M.gilvum_PYR-GCK VLPAPRPTDTRMILYTSGTTGRPKGVLHTHESLAALIAQLGRFWRIDRGD
Mvan_4966|M.vanbaalenii_PYR-1 TLPDLDPAATRMILYTSGTTGRPKGVLHSHKSLGALIAQLGRYWRIDPGD
TH_3067|M.thermoresistible__bu VLPALDPDAVRMILYTSGTTGRPKGVLHSHNSIHALIHQLREHWLIDPGD
MSMEG_5631|M.smegmatis_MC2_155 -LPALDPDSVRMMMHTSGTTGRPKGVLHSHNSIHALICQLRENWMIDPGD
MAV_5212|M.avium_104 -LPALDPDAVRMILYTSGTTSRPKGVLHTHNSIHALICQIRDHWAIDPGD
MMAR_0303|M.marinum_M PLPTADPDAVRMVLYTSGTTGRPKGVLHTHNSIHALICQIRDHWMVEPGD
MAB_2247c|M.abscessus_ATCC_199 PLPTVQTDTPALLLVSGGTTAAPKLIPRTHEDYVYNATQAARVCGLTQDD
MUL_3641|M.ulcerans_Agy99 --IDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLCRLTADD
Mb3116|M.bovis_AF2122/97 PAVECGGDDNLFIMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYRD
Rv3089|M.tuberculosis_H37Rv PAVECGGDDNLFIMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYRD
MLBr_01051|M.leprae_Br4923 -YPEPSPDATAMVIYTSGTTGPPKGVLLSRRAIAVDLDALAQAWQWTADD
::: :.***. ** : :: *
Mflv_1784|M.gilvum_PYR-GCK TFLVPSPIAHIGGSIYAFECP-----LLLGTEAVLMQRWDPDAAVGLMLE
Mvan_4966|M.vanbaalenii_PYR-1 TFLVPSPIAHIGGSIYAFECP-----LLLGTQAVLMQRWDPDAAVALMLR
TH_3067|M.thermoresistible__bu TFLVPSPIAHIGGSIYAFECP-----LLAGTTAVLMDRWRPDEAVRLMRA
MSMEG_5631|M.smegmatis_MC2_155 TFLVPSPIAHIGGSIYAFECP-----LLLGTTAVLMQRWNADDGVALMSE
MAV_5212|M.avium_104 TFLVPSPLAHIGGSIYAFECP-----LLLGTTAVLMDRWDPARAVALMTA
MMAR_0303|M.marinum_M GFLVASPIAHIGGSIYAFECP-----LLLGTTAVLLDRWDADRAVQLMTS
MAB_2247c|M.abscessus_ATCC_199 VYLVALPAGHN----FPLACPGLLGAISTGATTVFLSDPSPESAFATIAR
MUL_3641|M.ulcerans_Agy99 VYLVSLPAAHN----FPLACPGILGSMAVGATIVFSTDPSPEAAFTLIER
Mb3116|M.bovis_AF2122/97 RLLLPLPMFHVAALTTVIFSA------MRGVTLISMPQFDATKVWSLIVE
Rv3089|M.tuberculosis_H37Rv RLLLPLPMFHVAALTTVIFSA------MRGVTLISMPQFDATKVWSLIVE
MLBr_01051|M.leprae_Br4923 VLVHGLPLFHVHGLVLGLLGS-----LRIGNRFVHTGKPTPTAYAQACSE
: * * : . * : .
Mflv_1784|M.gilvum_PYR-GCK HRVTHMAGATPFLVGLLAAAQRAGTRLPDLKVFICGGASVPPTLIRSAAA
Mvan_4966|M.vanbaalenii_PYR-1 HRCTHMAGATPFLDGLLAAAERAGTRLPDLKVFICGGASVPPSLIRRAAD
TH_3067|M.thermoresistible__bu EHCTHMAGATPFLDGLLTAARQAGTRLPDLKVFICGGASVSPSLIRSAAD
MSMEG_5631|M.smegmatis_MC2_155 HHCTHMAGATPFLDQLLNAAERAGTRLPDLKVFICGGASVPPSLIRRAST
MAV_5212|M.avium_104 HRCTHMAGATPFLQQLLSAAANAGTRLPDLKVFICGGASVSPSLIRRAAA
MMAR_0303|M.marinum_M KRCTHMAGATPFLEQLLAAAQRAGTRLPDLKFFVCGGASVSPSLIRCATD
MAB_2247c|M.abscessus_ATCC_199 HRVSVTAVVPSLAQLWAQATAWEPVLPETLRLLQVGGAKLGADDARAVRE
MUL_3641|M.ulcerans_Agy99 HGVTVTALVPALAKLWTQACDWEPVIPKSLRLLQVGGSRLEPEDARQARE
Mb3116|M.bovis_AF2122/97 ERVCIGGAVPAILNFMRQVPEFAELDAPDFRYFITGGAPMPEALIKIYAA
Rv3089|M.tuberculosis_H37Rv ERVCIGGAVPAILNFMRQVPEFAELDAPDFRYFITGGAPMPEALIKIYAA
MLBr_01051|M.leprae_Br4923 AGGSLYFGVPTVWSRLVADEAVARALRP-ARLLVSGSASLPVP-VFDRLA
.... : : *.: :
Mflv_1784|M.gilvum_PYR-GCK YFDKAAVSRVYGSTEVPVTTVGALD--DIDRAADTDGRPGIAEVRIVD--
Mvan_4966|M.vanbaalenii_PYR-1 YFDKAAVSRVYGSTEVPVTTVGSLD--DVDRAADTDGRPGIADVTLVD--
TH_3067|M.thermoresistible__bu YFERAVVTRVYGSTEVPVTTVGVLGPADADRAAETDGRPGIAEVRLADHA
MSMEG_5631|M.smegmatis_MC2_155 CFEKAVVSRVYGSTEVPVTTVGSIEPGDVEHAACTDGRPGLAEIRLVD--
MAV_5212|M.avium_104 YFDRAVVTRVYGCTEVPVATVGAPRPQEADYAADTDGRPGIAEIKLVAHP
MMAR_0303|M.marinum_M YFDKAVVTRVYGSTEVPVTTIGAPD--SSAHAAATDGRVGAADVKLVA--
MAB_2247c|M.abscessus_ATCC_199 SLTQG-LQQVFGMAEGLLCLTQPGDPTDILDNSQGRPMCDADEVRIVDED
MUL_3641|M.ulcerans_Agy99 ALTPG-LQQVFGMAEGLLNFTRLEDPPDLLEHTQGRPLCSADELRIVDGA
Mb3116|M.bovis_AF2122/97 KNIEVVQGYALTESCGGGTLLLSEDALRKAGSAGRATMFTDVAVRGDDGV
Rv3089|M.tuberculosis_H37Rv KNIEVVQGYALTESCGGGTLLLSEDALRKAGSAGRATMFTDVAVRGDDGV
MLBr_01051|M.leprae_Br4923 HLTGHRPIERYGSTESLITLSTLADGERRAGWVGLPLAGVQTRLVDESGG
: :
Mflv_1784|M.gilvum_PYR-GCK ---------GEIRARGPQMFTGYLHP-EDDRESFDDAGYFRTGDLGRFTE
Mvan_4966|M.vanbaalenii_PYR-1 ---------GEIRARGPQMLTGYLHP-EDNSESFDAEGFFRTGDLGHLTD
TH_3067|M.thermoresistible__bu AAPPGA---GEVLARGPQMLVGYLHP-EDERDAFDADGFFRTGDLARWVD
MSMEG_5631|M.smegmatis_MC2_155 ---------GEIRARGPQMLLGYLHA-EDN--AFDEQGFFRTGDLGRWVD
MAV_5212|M.avium_104 AAPTGD---GEICVRGPQMLRGYRHP-EDDAESFDAAGFFRTGDLGRWAL
MMAR_0303|M.marinum_M ---------GEIRVRGPQMLVGYRHP-EDEAGSFDAQGYFRTGDLGHWVD
MAB_2247c|M.abscessus_ATCC_199 GADVPAGETGELLVRGPYTLNGYYRADADNMRSFTVDGFYRSGDRVRALP
MUL_3641|M.ulcerans_Agy99 GAPVAPGAEGELLVRGPYTINGYFCADRDNERCFDPAGFYRSGDLVRLRD
Mb3116|M.bovis_AF2122/97 IREHGE---GEVVIKSDILLKEYWNRPEATRDAFDN-GWFRTGDIGEIDD
Rv3089|M.tuberculosis_H37Rv IREHGE---GEVVIKSDILLKEYWNRPEATRDAFDN-GWFRTGDIGEIDD
MLBr_01051|M.leprae_Br4923 PVPYDGETVGRLQVRSPTMFGGYLNRPEATAEAFDEDGWYRTGDVAVVDS
*.: :. : * .* *::*:**
Mflv_1784|M.gilvum_PYR-GCK DN----HLVVTGRAKDIIIRNGENISPKEVEDILVTHPRIAEIAVVGIPD
Mvan_4966|M.vanbaalenii_PYR-1 DG----YLVVTGRAKDLIIRNGENISPKEVEDILVTHPQIAEIAIVGIPD
TH_3067|M.thermoresistible__bu GD----HLVITGRAKDIIIRNGENISPKEVEDLLIGHPGVAEIAVVGVPD
MSMEG_5631|M.smegmatis_MC2_155 GD----YLTVTGRAKDLIIRNGENISPKEIEDILVGELGINEIAVVGLPD
MAV_5212|M.avium_104 ADSADRYLVVTGRAKDVIIRSGENISAKEVEDLLADHPGIAEIAVVGLPD
MMAR_0303|M.marinum_M DE----YLVVTGRAKDIIIRNGENISPKEIEDILITHPGIADVAIVGLPD
MAB_2247c|M.abscessus_ATCC_199 GG----YLEVTGRIKDVILRGGESIAALDLESHLQTHPAVYAAAAVGLPD
MUL_3641|M.ulcerans_Agy99 DG----YLQVTGRVKDVICRCGETISAQDLEEQLLSHPAIRSAAAVPLPD
Mb3116|M.bovis_AF2122/97 EG----YLYIKDRLKDMIISGGENVYPAEIESVIIGVPGVSEVAVIGLPD
Rv3089|M.tuberculosis_H37Rv EG----YLYIKDRLKDMIISGGENVYPAEIESVIIGVPGVSEVAVIGLPD
MLBr_01051|M.leprae_Br4923 GG---MHRIVGRESVDLIKLGGYRIGAGEIEMALLGHPDVREVAVVGLPD
: : . *:* * : . ::* : : * : :**
Mflv_1784|M.gilvum_PYR-GCK PRTGERACAALVTTE--DPPPDIAELKDFLTDRGVARFKVPEQIHVVGAL
Mvan_4966|M.vanbaalenii_PYR-1 LRTGERACAVIVAAD--SAAPDVAEIRDFLVARGVAKFKAPERVVVVDAL
TH_3067|M.thermoresistible__bu PRTGERACAAIVPTG--RPGPDVAELREFLLARGVAKFKAPEQVVFFDAL
MSMEG_5631|M.smegmatis_MC2_155 ERTGERACAVVVTED--GARPDVSALAEVLTKAGVAKFKIPEQVEIWDAL
MAV_5212|M.avium_104 ERTGERACAVIVPTP--GASPDVASLLALLVSKGVAKFKAPEQVVLWDAL
MMAR_0303|M.marinum_M DRTGERACAVIVAAA--DPPPGLPGVRAFLEGAGVARFKIPEQVVIWDHL
MAB_2247c|M.abscessus_ATCC_199 QYLGEIVCAAIVFKG---KPVAAAELNQHLQARGAATHSRVDKLVAVSAL
MUL_3641|M.ulcerans_Agy99 PDMGELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIRIDRLVAMPSL
Mb3116|M.bovis_AF2122/97 EKWGEIAAAIVVADQ---NEVSEQQIVEYCGTR-LARYKLPKKVIFAEAI
Rv3089|M.tuberculosis_H37Rv EKWGEIAAAIVVADQ---NEVSEQQIVEYCGTR-LARYKLPKKVIFAEAI
MLBr_01051|M.leprae_Br4923 EDLGQRIVAFVVGAE----ALDADELINYVAQQ-LSIHKRPREVRFVDAL
*: * :* : : . .: :
Mflv_1784|M.gilvum_PYR-GCK PKNDAGKVLKHVLKAELTKES-----
Mvan_4966|M.vanbaalenii_PYR-1 PKNDAGKVLKHAIRAVLLEKPREGEP
TH_3067|M.thermoresistible__bu PKNDAGKVLKHQIQATLTAAEVSG--
MSMEG_5631|M.smegmatis_MC2_155 PKNDAGKVLKHQIRTQLSKVE-----
MAV_5212|M.avium_104 PKNDAGKVLKHRIRAALSKDG-----
MMAR_0303|M.marinum_M PKNHAGKIVKHRIKAALMKAEQ----
MAB_2247c|M.abscessus_ATCC_199 PLTAVGKIDKRALLASLTG-------
MUL_3641|M.ulcerans_Agy99 PTTPVGKIDKKAIASQILTTTAT---
Mb3116|M.bovis_AF2122/97 PRNPTGKILKTVLREQYSATVPK---
Rv3089|M.tuberculosis_H37Rv PRNPTGKILKTVLREQYSATVPK---
MLBr_01051|M.leprae_Br4923 PRNAMGKVLKKQLLFEG---------
* . **: * :