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M. thermoresistible (build 8) TH_3791 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 4588560 - 4589339
length: 260

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3791--100% (260)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_2623-4e-4846.46% (254) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4266-1e-3539.22% (255) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1963c-4e-3536.86% (255) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1263-6e-3539.30% (257) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1928c-4e-3536.86% (255) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG14e-2734.45% (238) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4680c-1e-3238.46% (247) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_2849-2e-3536.47% (255) short-chain type dehydrogenase/reductase
M. avium 104MAV_2775-1e-3738.82% (255) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_3604-3e-3837.40% (254) sorbitol utilization protein SOU2
M. ulcerans Agy99MUL_2173fabG3e-3134.98% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_0894-5e-6250.81% (248) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3791|M.thermoresistible__bu      MTANTG------ASVLD-MFRLTGRSAIVTGASSGLGRGFAQTLAAAGAT
Mvan_0894|M.vanbaalenii_PYR-1       MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
Mb1963c|M.bovis_AF2122/97           ------------MSVLD-LFDLHGKRALITGASTGIGKRVALAYVEAGAQ
Rv1928c|M.tuberculosis_H37Rv        ------------MSVLD-LFDLHGKRALITGASTGIGKRVALAYVEAGAQ
MMAR_2849|M.marinum_M               ------------MSVLD-LFDLSGKRALITGASTGIGKKVALAYAEAGAQ
MAV_2775|M.avium_104                --------------MLD-LFDLRGRRALVTGASTGIGKQVAQAYLQAGAR
MSMEG_3604|M.smegmatis_MC2_155      ------------MDVRS-AFDLSGRTALVTGGNQGLGKAFAIALAQAGAR
Mflv_1263|M.gilvum_PYR-GCK          --------------MSD-RFSMEGRVAVITGGGTGIGRASALVLAEHGAD
MUL_2173|M.ulcerans_Agy99           ---------------MT-SLDLTGRTAIITGASRGIGLAIAQRLAGAGAN
MLBr_01807|M.leprae_Br4923          ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
MAB_4680c|M.abscessus_ATCC_199      --------------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGR
                                                         : .:  ::**.  *:*   :      *  

TH_3791|M.thermoresistible__bu      VYAAARRTDRLETLAAENPAIR-----AVTCDVTDEQDRRALVERVVAET
Mvan_0894|M.vanbaalenii_PYR-1       VVVAARRADRLAELCEAHEGLS-----AVSCDVADPASIESAYQCVEERV
Mb1963c|M.bovis_AF2122/97           VAIAARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAEL
Rv1928c|M.tuberculosis_H37Rv        VAIAARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAEL
MMAR_2849|M.marinum_M               VAVAARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGEL
MAV_2775|M.avium_104                VAIAARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAEL
MSMEG_3604|M.smegmatis_MC2_155      VSFSGRNAERNEKTAAEAAAAG-HQLHAITADITRAEDVERMTAEAIEAL
Mflv_1263|M.gilvum_PYR-GCK          VVLAGRRAEPLKETAAEVEALG-RRALAVPTDVTDADACQALVDTTLAEF
MUL_2173|M.ulcerans_Agy99           VVLTARKQESADAAAAEVG----ERAVGVGAHAVDEEAARGCVDLALERF
MLBr_01807|M.leprae_Br4923          VAVT--------HRASVVPDWF----FGVECDVTDNDAIGAAFKAVEEHQ
MAB_4680c|M.abscessus_ATCC_199      VVIADVLDGDGRQLAAELGDAA----RFTHLDVTDAEQWRELIDTTLAGF
                                    *  :          .                .                  

TH_3791|M.thermoresistible__bu      GGVDVLVNNAG-KPGGPDAVKESADEFASILDLNLAAGFHLSCDVVRANP
Mvan_0894|M.vanbaalenii_PYR-1       GAVDILVNNAG-TSIPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKMI
Mb1963c|M.bovis_AF2122/97           GGIDIAVCNAG-IITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
Rv1928c|M.tuberculosis_H37Rv        GGIDIAVCNAG-IITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
MMAR_2849|M.marinum_M               GGIDIAVCNAG-IVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMV
MAV_2775|M.avium_104                GGIDIAVCNAG-IISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMV
MSMEG_3604|M.smegmatis_MC2_155      GHIDILVNNAG-TCHHGESWTVTEEQWDDVFDLNVKALWACSLAVGAHMR
Mflv_1263|M.gilvum_PYR-GCK          GRLDVLLNNAGGGETKS-LMKWTDDEWHHVLDLNLSSAWYLSRAAAKPMI
MUL_2173|M.ulcerans_Agy99           GSVDILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWM
MLBr_01807|M.leprae_Br4923          GPVEVLVANAG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
MAB_4680c|M.abscessus_ATCC_199      GTITGLVNNAG-ISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMR
                                    * :   : ***               :  : : *: .       .     

TH_3791|M.thermoresistible__bu      ENH-RLSIVNVSSVIGLVSTAPIGGAGYAASKAGVLGLTRELAGQWGRQG
Mvan_0894|M.vanbaalenii_PYR-1       ERG-EGSIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWARYN
Mb1963c|M.bovis_AF2122/97           KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
Rv1928c|M.tuberculosis_H37Rv        KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
MMAR_2849|M.marinum_M               DQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQ
MAV_2775|M.avium_104                RQGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHD
MSMEG_3604|M.smegmatis_MC2_155      ERG-SGSVVNIGSMSGIIVNRPQMQPAYNASKAAVHHLTKSLAAEWAPLG
Mflv_1263|M.gilvum_PYR-GCK          AQG-SGAIVNISSGAG--LLAMPQAPIYGAAKAGLQNLTGSMAAAWTRKG
MUL_2173|M.ulcerans_Agy99           GEH-GGVVINTASIGG--MHQSPAMGMYNATNAALIHVTKQLALELSPR-
MLBr_01807|M.leprae_Br4923          KQR-FGRYIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGSRS
MAB_4680c|M.abscessus_ATCC_199      AHG-CGSIVNISSAAG--LVGLALTSGYGASKWGVRGLSKVAAIELGRER
                                     .      :  .*  *           * ::: .:  ::   *       

TH_3791|M.thermoresistible__bu      IRVNALVPGWFDTEMTDGLFTNER-SATWVRRNTMLNRGGREGEVDGALL
Mvan_0894|M.vanbaalenii_PYR-1       VRVNALAPGFFPSELTTELLDDDA-GGAYIRRNTPMARAGRAGELSGALL
Mb1963c|M.bovis_AF2122/97           IRVNSVSPGYILTELVEP-YTEYQ---PLWEPKIPLGRLGRPEELAGLYL
Rv1928c|M.tuberculosis_H37Rv        IRVNSVSPGYILTELVEP-YTEYQ---PLWEPKIPLGRLGRPEELAGLYL
MMAR_2849|M.marinum_M               IRVNSVSPGYIRTELVEP-LADYH---ALWEPKIPLGRMGRPEELTGLYL
MAV_2775|M.avium_104                IRVNSVSPGYIRTELVEP-LHEYH---RQWQPKIPLGRMGRPDELAGIYL
MSMEG_3604|M.smegmatis_MC2_155      IRVNALAPGYVKTDMAPVDRPEFK---RYWIDDTPQLRYAVPEEIAPSVV
Mflv_1263|M.gilvum_PYR-GCK          VRVNCIACGAVRTPGLEADAKRQGFDIDMIGQTNGSGRIAEPDEIGYGVL
MUL_2173|M.ulcerans_Agy99           VRVNAICPGVVRTKLAEALWKDH---EDPLAANIALGRIGEPVDVAEAVG
MLBr_01807|M.leprae_Br4923          ITANVVAPGFIDTEMTRAMDSKYQ---EAALQAIPLGRIGAVEEIAGAVS
MAB_4680c|M.abscessus_ATCC_199      IRVNSVHPGVIYTPMTAKEGFREG---EGNMPIAAMGRVGNADEVAGAVA
                                    : .* :  * . :                        * .   ::     

TH_3791|M.thermoresistible__bu      FLASDASSYVTGQAIVVDGGWTAR-------------
Mvan_0894|M.vanbaalenii_PYR-1       LLASGAGSFITGQVIAVDGGWTAR-------------
Mb1963c|M.bovis_AF2122/97           YLASEASSYMTGSDIVIDGGYTCP-------------
Rv1928c|M.tuberculosis_H37Rv        YLASEASSYMTGSDIVIDGGYTCP-------------
MMAR_2849|M.marinum_M               YLASAASSYMTGSDIVIDGGYTCP-------------
MAV_2775|M.avium_104                YLASAASSYMTGSDIVIDGGYSCP-------------
MSMEG_3604|M.smegmatis_MC2_155      FLASDAASFITGSVLVADGGYTAW-------------
Mflv_1263|M.gilvum_PYR-GCK          FFASDASSYCSGQTLYMHGGPGPAGV-----------
MUL_2173|M.ulcerans_Agy99           FLVSDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MLBr_01807|M.leprae_Br4923          FLASEDAGYISGAVIPVDGGLGMGH------------
MAB_4680c|M.abscessus_ATCC_199      YLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ----
                                     : *  ..: :*  :  .**