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MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVLTARKQESADAAAAEVGERAVGVGAHAVDEEAAR GCVDLALERFGSVDILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHGGVVINT ASIGGMHQSPAMGMYNATNAALIHVTKQLALELSPRVRVNAICPGVVRTKLAEALWKDHEDPLAANIALG RIGEPVDVAEAVGFLVSDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2173 | fabG | - | 100% (260) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. ulcerans Agy99 | MUL_4384 | - | 1e-33 | 35.37% (246) | short-chain type dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_4111 | - | 1e-32 | 34.66% (251) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 1e-130 | 87.21% (258) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1202 | - | 2e-37 | 35.39% (243) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 1e-130 | 87.21% (258) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-27 | 31.25% (240) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 1e-36 | 37.55% (245) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 1e-145 | 99.62% (260) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 1e-125 | 85.16% (256) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_3262 | - | 3e-38 | 38.74% (253) | L-xylulose reductase |
| M. thermoresistible (build 8) | TH_3708 | - | 4e-41 | 38.06% (247) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_5605 | - | 9e-38 | 37.14% (245) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2173|M.ulcerans_Agy99 -----MT--------SLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MMAR_1952|M.marinum_M -----MT--------SLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
Mb2788c|M.bovis_AF2122/97 -----MT--------SLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -----MT--------SLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAV_3655|M.avium_104 -----MT--------SQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
Mflv_1202|M.gilvum_PYR-GCK -----MT---GFADRLFDLTDRVVLITGGSRGLGREMAVAAAHCGADVII
Mvan_5605|M.vanbaalenii_PYR-1 -----MTASGGFADQLFDLTDRVVLVTGGSRGLGREMAFAAARCGADVVI
TH_3708|M.thermoresistible__bu -----MT---PDPLAAFRLDGKVALVTGGSRGLGFEMARAFAGAGADVII
MAB_0833|M.abscessus_ATCC_1997 -----MN--RETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MSMEG_3262|M.smegmatis_MC2_155 -----MTTTDDRYAGVLRLDGKRALITGATKGIGADIARAFAAAGARLVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
. : .: ::**..:*:* :* . * : :
MUL_2173|M.ulcerans_Agy99 TARKQESADAAAAEVG----ERAVGVGAHAVDEEAARGCVDLALERFGSV
MMAR_1952|M.marinum_M TARKQESADAAAAEVG----ERAVGVGAHAVDEEAARGCVDLALERFGSV
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFGSV
MAV_3655|M.avium_104 TARKQEAADEAAAQVG----PQALGVGAHAVDEDAARQCVQLTLERFGSV
Mflv_1202|M.gilvum_PYR-GCK ASRKYDACVATAEEITAQTGRAALPYGVHVGRWDELDGLVDAAYARFGKV
Mvan_5605|M.vanbaalenii_PYR-1 ASRKYEACVATADEIAAETGRAAFPYQVHVGRWDELDGLVDAAYDRFGRV
TH_3708|M.thermoresistible__bu SSRDEESCRRAAEEIGRTFAVRAVPMPCHVGRWAELDALADRALATFGHV
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLR-SLGARALGVPTHTGDIHSLEELVRATAEEFGGI
MSMEG_3262|M.smegmatis_MC2_155 SGRDVSELDAARRALGEQFGTDVHTVAIDLAEPDAPAELARRAAEAFGGL
MLBr_01807|M.leprae_Br4923 THR--------ASVVP----DWFFGVECDVTDNDAIGAAFKAVEEHQGPV
: * : . . * :
MUL_2173|M.ulcerans_Agy99 DILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEH
MMAR_1952|M.marinum_M DILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEH
Mb2788c|M.bovis_AF2122/97 DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
MAV_3655|M.avium_104 DILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEH
Mflv_1202|M.gilvum_PYR-GCK DVLVNNAGMSPVYDKQSDVTEKLFDAVVNLNLKGPFRLSALIGERMVADG
Mvan_5605|M.vanbaalenii_PYR-1 DVLVNNAGMSPLYESLSAVTEKLFDSVVNLNLKGPFRLSVLVGDRMVADG
TH_3708|M.thermoresistible__bu DVLVNNAGMSPLYDKVADITETMWEKTLAVNLRAPFRLTALLAPAMVDNG
MAB_0833|M.abscessus_ATCC_1997 DIVVNNAAN-ALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP
MSMEG_3262|M.smegmatis_MC2_155 DVLVNNAGISHPQP-VVDTDPQLFDATIAVNLRAPALLASAVGKAMVAAG
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQ-FQKVIDVNLTGVFRVAKLASRNMIKQR
:::: **. : . :** . :
MUL_2173|M.ulcerans_Agy99 -GGVVINTASIGGMHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVNA
MMAR_1952|M.marinum_M -GGVVINTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNA
Mb2788c|M.bovis_AF2122/97 -GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
Rv2766c|M.tuberculosis_H37Rv -GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
MAV_3655|M.avium_104 -GGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNA
Mflv_1202|M.gilvum_PYR-GCK -GGSIVNVSTHGSLRPHPSFIPYAASKAGLNAMTEGLALAFGPS-VRVNT
Mvan_5605|M.vanbaalenii_PYR-1 -GGSIINVSTHGSIRPHPSFVPYAASKAGLNAMTEALALAYGPT-VRVNT
TH_3708|M.thermoresistible__bu -GGSVINLSSIGAVRPTADIVPYAAAKAGLNAMTAALAKEYGPH-VRVNA
MAB_0833|M.abscessus_ATCC_1997 -HAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNA
MSMEG_3262|M.smegmatis_MC2_155 EGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANS
MLBr_01807|M.leprae_Br4923 -FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
. : : .. * ::::.* : * .. : .*
MUL_2173|M.ulcerans_Agy99 ICPGVVRTKLAEALWK-DHEDP-LAANIALGRIGEPVDVAEAVGFLVSDA
MMAR_1952|M.marinum_M ICPGVVRTKLAEALWK-DHEDP-LAANIALGRIGEPVDVAEAVGFLVSDA
Mb2788c|M.bovis_AF2122/97 ICPGVVRTRLAEALWK-DHEDP-LAATIALGRIGEPADIASAVAFLVSDA
Rv2766c|M.tuberculosis_H37Rv ICPGVVRTRLAEALWK-DHEDP-LAATIALGRIGEPADIASAVAFLVSDA
MAV_3655|M.avium_104 IAPGVVRTRLAEALWK-DHEDP-LSSSIALGRIGEPIDVAAAVAFLVSDA
Mflv_1202|M.gilvum_PYR-GCK LMPGPFLTDISNAWNF-EGTDN-PFRGSALQRAGQPAEIVGAALFLMSDA
Mvan_5605|M.vanbaalenii_PYR-1 LMPGPFLTDISDAWTFTDGDTN-PFGHSALQRAGQPAEIVGAALFLMSDA
TH_3708|M.thermoresistible__bu IMPGAFATDVSEYWSA-EAVAR-VVDQTALGRIGDPREIVGTALYLASDA
MAB_0833|M.abscessus_ATCC_1997 LAPGAIDTDMVRKTPP-AEVER-MANTNHLKRLGLPDEMVGTALLLTSDA
MSMEG_3262|M.smegmatis_MC2_155 VCPTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDA
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASED
: * . * : * * . :: :. * *:
MUL_2173|M.ulcerans_Agy99 ASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MMAR_1952|M.marinum_M ASWITGETMVIDGGLLLGSAAGFQSRPGSAS
Mb2788c|M.bovis_AF2122/97 ASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv ASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAV_3655|M.avium_104 ASWITGETLVIDGGTVLGAAQGFRSAPTPS-
Mflv_1202|M.gilvum_PYR-GCK SSFTTGSIVRADGGSA---------------
Mvan_5605|M.vanbaalenii_PYR-1 SSFTTGSIVRADGGIP---------------
TH_3708|M.thermoresistible__bu ASFTSGAVITVDGGRD---------------
MAB_0833|M.abscessus_ATCC_1997 GSYITGQTIIADGGLVAR-------------
MSMEG_3262|M.smegmatis_MC2_155 ASMINGVDIPVDGGYTMG-------------
MLBr_01807|M.leprae_Br4923 AGYISGAVIPVDGGLGMGH------------
.. .* : ***