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M. thermoresistible (build 8) TH_3505 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3957336 - 3958151
length: 272

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3505--100% (272)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3420-7e-4040.08% (257) PUTATIVE oxidoreductase, short chain dehydrogenase/reductase
M. thermoresistible (build 8)TH_3954-8e-3939.33% (239) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0950c-6e-3739.75% (244) short chain dehydrogenase
M. gilvum PYR-GCKMflv_2424-1e-11070.79% (267) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0927c-6e-3739.75% (244) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG13e-2935.71% (238) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0833-2e-3936.99% (246) Short-chain dehydrogenase/reductase
M. marinum MMMAR_4756-1e-10367.91% (268) oxidoreductase
M. avium 104MAV_0894-1e-11675.66% (267) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155MSMEG_4850-1e-11475.37% (268) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_0327-1e-10367.91% (268) oxidoreductase
M. vanbaalenii PYR-1Mvan_4228-1e-11472.28% (267) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0950c|M.bovis_AF2122/97           -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
Rv0927c|M.tuberculosis_H37Rv        -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
MAB_0833|M.abscessus_ATCC_1997      -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MMAR_4756|M.marinum_M               ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASVAI
MUL_0327|M.ulcerans_Agy99           ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MAV_0894|M.avium_104                ---------MAIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAI
Mflv_2424|M.gilvum_PYR-GCK          ---------MAITASDILLTGRVAVVTGGGAGIGRGIAQGLAAFGASVAI
Mvan_4228|M.vanbaalenii_PYR-1       ---------MTIAPSDILLTGRVAVVTGGGAGIGKGIAHGLAAFGASVAI
MSMEG_4850|M.smegmatis_MC2_155      ---------MAINPSDILLTGRVAVVTGGGAGIGRGIAEGLAAFGARVAI
TH_3505|M.thermoresistible__bu      ---------LTIAPADILLTDRVAVVTGGGAGLGRGIAAGFAAFGARVAI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  ::**.  *:* .:*   .  *  : :

Mb0950c|M.bovis_AF2122/97           ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
Rv0927c|M.tuberculosis_H37Rv        ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
MAB_0833|M.abscessus_ATCC_1997      ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
MMAR_4756|M.marinum_M               WERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGEVT
MUL_0327|M.ulcerans_Agy99           WERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGAVT
MAV_0894|M.avium_104                WERDAQTCTRAAESIGGLG-----IVTDVRDSGQVDTALQRTITELGTPT
Mflv_2424|M.gilvum_PYR-GCK          WERDPDTCAAAAAAIGGLG-----LEVDVRDAAAVDTALDRTERELGTVS
Mvan_4228|M.vanbaalenii_PYR-1       WERDPQTCGEAAASVGALG-----LPTDVRDAEAVQAALERTERELGTVS
MSMEG_4850|M.smegmatis_MC2_155      WERDPETCEAAARAVGGVG-----IVTDVRDADQVDAALAQTTSELGTVS
TH_3505|M.thermoresistible__bu      WERDPDSCARTAEEIGALG-----IVTDVRDSAAVSAALRQTTEQLGSPT
MLBr_01807|M.leprae_Br4923          THR------ASVVPDWFFG-----VECDVTDNDAIGAAFKAVEEHQGPVE
                                      *        .      *     :  .             .    *   

Mb0950c|M.bovis_AF2122/97           IVVNNVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGG
Rv0927c|M.tuberculosis_H37Rv        IVVNNVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGG
MAB_0833|M.abscessus_ATCC_1997      IVVNNAANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP-H
MMAR_4756|M.marinum_M               ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAELP
MUL_0327|M.ulcerans_Agy99           ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAGLP
MAV_0894|M.avium_104                ILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAG
Mflv_2424|M.gilvum_PYR-GCK          ILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAAEQT
Mvan_4228|M.vanbaalenii_PYR-1       ILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVGQP
MSMEG_4850|M.smegmatis_MC2_155      ILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAEMP
TH_3505|M.thermoresistible__bu      ILVNNAGGTFSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAGQP
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR-F
                                    ::* *.. .    :   : .        *:      .      ::     

Mb0950c|M.bovis_AF2122/97           GSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIA
Rv0927c|M.tuberculosis_H37Rv        GSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIA
MAB_0833|M.abscessus_ATCC_1997      AAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNALA
MMAR_4756|M.marinum_M               GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNAIA
MUL_0327|M.ulcerans_Agy99           GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNAIA
MAV_0894|M.avium_104                GSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNAIA
Mflv_2424|M.gilvum_PYR-GCK          GSVINVTSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPYGIRVNGLA
Mvan_4228|M.vanbaalenii_PYR-1       GSVINITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNALA
MSMEG_4850|M.smegmatis_MC2_155      GSIINLTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNALA
TH_3505|M.thermoresistible__bu      GSIVNITSIEGARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNAIA
MLBr_01807|M.leprae_Br4923          GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
                                    .  : : *  .       : *.::*:.:   :   : :*    : .* :*

Mb0950c|M.bovis_AF2122/97           PGSILTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGS
Rv0927c|M.tuberculosis_H37Rv        PGSILTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGS
MAB_0833|M.abscessus_ATCC_1997      PGAIDTDMVRKTPPAEVER--MANTNHLKRLGLPDEMVGTALLLTSDAGS
MMAR_4756|M.marinum_M               PDITMTEGLAQLGG-AAALERIGSLVPLGRPGDIDEIASVAVFLASDMAR
MUL_0327|M.ulcerans_Agy99           PDITMTEGLAQLGG-AAALERIGSLVPLGRPGDVDEIASVAVFLASDMAR
MAV_0894|M.avium_104                PDITLTEGLQQLGG-EAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSG
Mflv_2424|M.gilvum_PYR-GCK          PDLTMTEGLQKLAF-GELSGTVARMVPMRRAGHVDEMASAAVFLASDMAS
Mvan_4228|M.vanbaalenii_PYR-1       PDLTMTEGLQKLAF-GDLSGTMADMVPMRRVGHVDEMASAAVFLASDMAA
MSMEG_4850|M.smegmatis_MC2_155      PDLTVTDGLLALSG-GRQPG--GDAIPMKRPGHVDEMAGAAVFLASGMSS
TH_3505|M.thermoresistible__bu      PDIAVTEGLQRMSP-DGIPPEVGHAIPLGRPGHVDEIAGAAVFLASEMSS
MLBr_01807|M.leprae_Br4923          PGFIDTEMTRAMDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAG
                                    *.   *.                    : * *   ::....  *:*  . 

Mb0950c|M.bovis_AF2122/97           FLTGKTLEVDGGLTFPNLDLPIPDL-----------
Rv0927c|M.tuberculosis_H37Rv        FLTGKTLEVDGGLTFPNLDLPIPDL-----------
MAB_0833|M.abscessus_ATCC_1997      YITGQTIIADGGLVAR--------------------
MMAR_4756|M.marinum_M               YVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MUL_0327|M.ulcerans_Agy99           YVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MAV_0894|M.avium_104                YLTGQTLHVDGGTQASSGWYHDPRTGDYRLGPAG--
Mflv_2424|M.gilvum_PYR-GCK          YITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA---
Mvan_4228|M.vanbaalenii_PYR-1       YITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA---
MSMEG_4850|M.smegmatis_MC2_155      YITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG---
TH_3505|M.thermoresistible__bu      YITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR
MLBr_01807|M.leprae_Br4923          YISGAVIPVDGGLGMGH-------------------
                                    :::* .: .***