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M. thermoresistible (build 8) TH_3420 (-)

annotation: oxidoreductase, short chain dehydrogenase/reductase family protein
coordinates: 1806770 - 1807591
length: 274

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3420 - - 100% (274) oxidoreductase, short chain dehydrogenase/reductase family protein
M. thermoresistible (build 8) TH_3693 - 2e-44 42.52% (254) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3954 - 8e-42 40.48% (252) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1385 fabG 3e-46 42.80% (257) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCK Mflv_2415 - 1e-101 71.43% (266) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1350 fabG 3e-46 42.80% (257) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923 MLBr_01807 fabG1 6e-26 30.68% (251) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_4680c - 3e-39 38.22% (259) putative short-chain dehydrogenase/reductase
M. marinum M MMAR_4765 - 1e-108 74.05% (262) short chain dehydrogenase
M. avium 104 MAV_0886 - 1e-104 72.62% (263) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155 MSMEG_4859 - 1e-115 80.23% (263) oxidoreductase, short chain dehydrogenase/reductase family
M. ulcerans Agy99 MUL_0336 - 1e-108 73.28% (262) short chain dehydrogenase
M. vanbaalenii PYR-1 Mvan_4237 - 1e-101 70.68% (266) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1385|M.bovis_AF2122/97            --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv         --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
TH_3420|M.thermoresistible__bu      -----------VTERAGELAGKVAVVTGGAAGLGAGLARRFVAEGAKVLI
MSMEG_4859|M.smegmatis_MC2_155      ---------------MSELAGRVAVVTGGASGLGEGLVRRFVAEGAQVMI
MMAR_4765|M.marinum_M               --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MUL_0336|M.ulcerans_Agy99           --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MAV_0886|M.avium_104                --------------MVNELAGKVAIVTGGASGIGRGIVERFVAEGARVVI
Mflv_2415|M.gilvum_PYR-GCK          ---------------MTELAGKVAVVTGGASGIGRGIAARFAAEGAAVVI
Mvan_4237|M.vanbaalenii_PYR-1       ---------------MTELVGKVAIVTGGASGIGRGIAERFAAEGARVVI
MAB_4680c|M.abscessus_ATCC_199      -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  ::***  *:* .   :: ::*  * :

Mb1385|M.bovis_AF2122/97            GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
Rv1350|M.tuberculosis_H37Rv         GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
TH_3420|M.thermoresistible__bu      GDVDTGNGAKLAAEL---GADAEFVEADVADLDQVSGLVSTAVERFGGLH
MSMEG_4859|M.smegmatis_MC2_155      GDVDKDRGTALAEEL---GAHTEFLTTDVADQEQVAALVSAGVERFGGLH
MMAR_4765|M.marinum_M               ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVENFGGLH
MUL_0336|M.ulcerans_Agy99           ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVDNFGGLH
MAV_0886|M.avium_104                ADIETERGERLAAEL---GGEAVFRRTDVSDIEQVGALVAAAVEKFGGLH
Mflv_2415|M.gilvum_PYR-GCK          ADVRDDLGEALVRELNESGAKTVYRHTDVGDQAQVADLVSSTVETFGALN
Mvan_4237|M.vanbaalenii_PYR-1       ADVRDDLGEPLAAELNSRGAKTVYRHTDVGDQRQVAELVAAAVDTFGGLD
MAB_4680c|M.abscessus_ATCC_199      ADVLDGDGRQLAAEL---GDAARFTHLDVTDAEQWRELIDTTLAGFGTIT
MLBr_01807|M.leprae_Br4923          THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
                                     .                         ** :       . :     * : 

Mb1385|M.bovis_AF2122/97            VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
Rv1350|M.tuberculosis_H37Rv         VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
TH_3420|M.thermoresistible__bu      VMVNNAGISGTMHRSLLDDDLADFDRVMRINVRAVMAGTRDAARHMAEHG
MSMEG_4859|M.smegmatis_MC2_155      VMVNNAGVSGTMHRRFLDDDLADFHKVMGVNVLGVMAGTREAARYMADNG
MMAR_4765|M.marinum_M               VMVNNAGVSGVMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MUL_0336|M.ulcerans_Agy99           VMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MAV_0886|M.avium_104                VMVNNAGISSPLRR-LLDDDLADFHRVMGVNVLGVMAGTRDAARHMADNG
Mflv_2415|M.gilvum_PYR-GCK          VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAARHMADHG
Mvan_4237|M.vanbaalenii_PYR-1       VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAGRYMADHG
MAB_4680c|M.abscessus_ATCC_199      GLVNNAGISS--AAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSE--EQFQKVIDVNLTGVFRVAKLASRNMIKQR
                                     :* ***::         :   .* :*: ::: ..    : .   *  . 

Mb1385|M.bovis_AF2122/97            RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
Rv1350|M.tuberculosis_H37Rv         RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
TH_3420|M.thermoresistible__bu      GGSIINLTSIGGIQAGGGVQTYRASKAAVIQFTKSAAIELAHHEIRVNAL
MSMEG_4859|M.smegmatis_MC2_155      GGSILNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHHEIRVNAI
MMAR_4765|M.marinum_M               GGSIVNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHYEIRVNAI
MUL_0336|M.ulcerans_Agy99           GGSIVNLTSIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNAI
MAV_0886|M.avium_104                GGAIINLTSIGGIQAGGGVMTYRASKAAVIQFTKAAAIELARYDIRVNAI
Mflv_2415|M.gilvum_PYR-GCK          GGSVINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
Mvan_4237|M.vanbaalenii_PYR-1       GGSIINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
MAB_4680c|M.abscessus_ATCC_199      CGSIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSV
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
                                     *  : : *  *  .      * *:* .:  :::  * **.   : .* :

Mb1385|M.bovis_AF2122/97            APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
Rv1350|M.tuberculosis_H37Rv         APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
TH_3420|M.thermoresistible__bu      APGNIRTAIVRKSATGADLERLERFEARIRQQMRDDRPLKREGTVEDVAE
MSMEG_4859|M.smegmatis_MC2_155      APGNIRTAIVAKSASEEDRQRIEEFEANIRAQMRADRPLKREGTVEDVAE
MMAR_4765|M.marinum_M               APGNIPTPLLASSAAGMDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MUL_0336|M.ulcerans_Agy99           APGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MAV_0886|M.avium_104                APGNIPTPILGKSAGDMDPEQRERFEARIREGMREDRPLKREGTPDDVAE
Mflv_2415|M.gilvum_PYR-GCK          APGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKREGTADDVAE
Mvan_4237|M.vanbaalenii_PYR-1       APGNIPTPILASSATDEDRERLERFEARIRRQMRDDRPLKREGTAEDVAE
MAB_4680c|M.abscessus_ATCC_199      HPGVIYTPMTAK----------EGFRE--GEGNMPIAAMGRVGNADEVAG
MLBr_01807|M.leprae_Br4923          APGFIDTEMTR------------AMDSKYQEAALQAIPLGRIGAVEEIAG
                                     ** * : :               :            .: * *  .::* 

Mb1385|M.bovis_AF2122/97            VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
Rv1350|M.tuberculosis_H37Rv         VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
TH_3420|M.thermoresistible__bu      AALYFAGDRSRYVTGTVLPIDGGTVAGKVIARKSHAE----
MSMEG_4859|M.smegmatis_MC2_155      AALYFATDRSRYVTGTVLPIDGGTVAGKVIVRKEKR-----
MMAR_4765|M.marinum_M               AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MUL_0336|M.ulcerans_Agy99           AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MAV_0886|M.avium_104                AALYFATERSRYVTGTVLPVDGGTSAGKAMRSKRQG-----
Mflv_2415|M.gilvum_PYR-GCK          AALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ---
Mvan_4237|M.vanbaalenii_PYR-1       AALYLATDRSRYITGTVLPVDGGTVAGKVIVRKPPPAEAAT
MAB_4680c|M.abscessus_ATCC_199      AVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ-----
MLBr_01807|M.leprae_Br4923          AVSFLASEDAGYISGAVIPVDGGLGMGH-------------
                                    .. ::  : : *::*: : : *    *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3420	-	-	100% (274)	oxidoreductase, short chain dehydrogenase/reductase family protein
M. thermoresistible (build 8)	TH_3693	-	2e-44	42.52% (254)	PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3954	-	8e-42	40.48% (252)	PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase