For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TIAPSDILLTGRVAVVTGGGAGIGKGIAHGLAAFGASVAIWERDPQTCGEAAASVGALGLPTDVRDAEAV QAALERTERELGTVSILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVGQPGSVIN ITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNALAPDLTMTEGLQKLAFGDLSGTMADMV PMRRVGHVDEMASAAVFLASDMAAYITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4228 | - | - | 100% (268) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4921 | - | 2e-36 | 38.52% (244) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0441 | - | 2e-35 | 38.21% (246) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 8e-36 | 37.30% (244) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 1e-132 | 86.94% (268) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0927c | - | 8e-36 | 37.30% (244) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-27 | 32.77% (235) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 3e-41 | 39.02% (246) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4756 | - | 1e-105 | 70.79% (267) | oxidoreductase |
| M. avium 104 | MAV_0894 | - | 1e-109 | 72.76% (268) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_4850 | - | 1e-112 | 74.91% (267) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3505 | - | 1e-114 | 72.28% (267) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0327 | - | 1e-105 | 70.79% (267) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0950c|M.bovis_AF2122/97 -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
Rv0927c|M.tuberculosis_H37Rv -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
MAB_0833|M.abscessus_ATCC_1997 -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
Mvan_4228|M.vanbaalenii_PYR-1 ---------MTIAPSDILLTGRVAVVTGGGAGIGKGIAHGLAAFGASVAI
Mflv_2424|M.gilvum_PYR-GCK ---------MAITASDILLTGRVAVVTGGGAGIGRGIAQGLAAFGASVAI
MSMEG_4850|M.smegmatis_MC2_155 ---------MAINPSDILLTGRVAVVTGGGAGIGRGIAEGLAAFGARVAI
MMAR_4756|M.marinum_M ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASVAI
MUL_0327|M.ulcerans_Agy99 ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MAV_0894|M.avium_104 ---------MAIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAI
TH_3505|M.thermoresistible__bu ---------LTIAPADILLTDRVAVVTGGGAGLGRGIAAGFAAFGARVAI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: ::**. *:* .:* . * : :
Mb0950c|M.bovis_AF2122/97 ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
Rv0927c|M.tuberculosis_H37Rv ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
Mvan_4228|M.vanbaalenii_PYR-1 WERDPQTCGEAAASVGALG-----LPTDVRDAEAVQAALERTERELGTVS
Mflv_2424|M.gilvum_PYR-GCK WERDPDTCAAAAAAIGGLG-----LEVDVRDAAAVDTALDRTERELGTVS
MSMEG_4850|M.smegmatis_MC2_155 WERDPETCEAAARAVGGVG-----IVTDVRDADQVDAALAQTTSELGTVS
MMAR_4756|M.marinum_M WERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGEVT
MUL_0327|M.ulcerans_Agy99 WERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGAVT
MAV_0894|M.avium_104 WERDAQTCTRAAESIGGLG-----IVTDVRDSGQVDTALQRTITELGTPT
TH_3505|M.thermoresistible__bu WERDPDSCARTAEEIGALG-----IVTDVRDSAAVSAALRQTTEQLGSPT
MLBr_01807|M.leprae_Br4923 THR------ASVVPDWFFG-----VECDVTDNDAIGAAFKAVEEHQGPVE
* . * : . . *
Mb0950c|M.bovis_AF2122/97 IVVNNVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGG
Rv0927c|M.tuberculosis_H37Rv IVVNNVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGG
MAB_0833|M.abscessus_ATCC_1997 IVVNNAANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP-H
Mvan_4228|M.vanbaalenii_PYR-1 ILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVGQP
Mflv_2424|M.gilvum_PYR-GCK ILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAAEQT
MSMEG_4850|M.smegmatis_MC2_155 ILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAEMP
MMAR_4756|M.marinum_M ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAELP
MUL_0327|M.ulcerans_Agy99 ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAGLP
MAV_0894|M.avium_104 ILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAG
TH_3505|M.thermoresistible__bu ILVNNAGGTFSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAGQP
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR-F
::* *.. . : : . *: . ::
Mb0950c|M.bovis_AF2122/97 GSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIA
Rv0927c|M.tuberculosis_H37Rv GSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIA
MAB_0833|M.abscessus_ATCC_1997 AAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNALA
Mvan_4228|M.vanbaalenii_PYR-1 GSVINITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNALA
Mflv_2424|M.gilvum_PYR-GCK GSVINVTSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPYGIRVNGLA
MSMEG_4850|M.smegmatis_MC2_155 GSIINLTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNALA
MMAR_4756|M.marinum_M GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNAIA
MUL_0327|M.ulcerans_Agy99 GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNAIA
MAV_0894|M.avium_104 GSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNAIA
TH_3505|M.thermoresistible__bu GSIVNITSIEGARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNAIA
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
. : : * . : *.::*:.: : : :* : .* :*
Mb0950c|M.bovis_AF2122/97 PGSILTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGS
Rv0927c|M.tuberculosis_H37Rv PGSILTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGS
MAB_0833|M.abscessus_ATCC_1997 PGAIDTDMVRKTPPAEVER--MANTNHLKRLGLPDEMVGTALLLTSDAGS
Mvan_4228|M.vanbaalenii_PYR-1 PDLTMTEGLQKLAF-GDLSGTMADMVPMRRVGHVDEMASAAVFLASDMAA
Mflv_2424|M.gilvum_PYR-GCK PDLTMTEGLQKLAF-GELSGTVARMVPMRRAGHVDEMASAAVFLASDMAS
MSMEG_4850|M.smegmatis_MC2_155 PDLTVTDGLLALSG-GRQPG--GDAIPMKRPGHVDEMAGAAVFLASGMSS
MMAR_4756|M.marinum_M PDITMTEGLAQLGG-AAALERIGSLVPLGRPGDIDEIASVAVFLASDMAR
MUL_0327|M.ulcerans_Agy99 PDITMTEGLAQLGG-AAALERIGSLVPLGRPGDVDEIASVAVFLASDMAR
MAV_0894|M.avium_104 PDITLTEGLQQLGG-EAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSG
TH_3505|M.thermoresistible__bu PDIAVTEGLQRMSP-DGIPPEVGHAIPLGRPGHVDEIAGAAVFLASEMSS
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAG
*. *. : * * ::.... *:* .
Mb0950c|M.bovis_AF2122/97 FLTGKTLEVDGGLTFPNLDLPIPDL-----------
Rv0927c|M.tuberculosis_H37Rv FLTGKTLEVDGGLTFPNLDLPIPDL-----------
MAB_0833|M.abscessus_ATCC_1997 YITGQTIIADGGLVAR--------------------
Mvan_4228|M.vanbaalenii_PYR-1 YITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA---
Mflv_2424|M.gilvum_PYR-GCK YITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA---
MSMEG_4850|M.smegmatis_MC2_155 YITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG---
MMAR_4756|M.marinum_M YVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MUL_0327|M.ulcerans_Agy99 YVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MAV_0894|M.avium_104 YLTGQTLHVDGGTQASSGWYHDPRTGDYRLGPAG--
TH_3505|M.thermoresistible__bu YITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR
MLBr_01807|M.leprae_Br4923 YISGAVIPVDGGLGMGH-------------------
:::* .: .***