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AINPSDILLTGRVAVVTGGGAGIGRGIAEGLAAFGARVAIWERDPETCEAAARAVGGVGIVTDVRDADQV DAALAQTTSELGTVSILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAEMPGSIIN LTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNALAPDLTVTDGLLALSGGRQPGGDAIPM KRPGHVDEMAGAAVFLASGMSSYITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4850 | - | - | 100% (266) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_1740 | - | 9e-39 | 38.78% (245) | dehydrogenase/reductase SDR family protein member 4 |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 6e-37 | 37.50% (248) | 2-deoxy-D-gluconate 3-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 7e-34 | 36.89% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 1e-115 | 76.78% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1350 | fabG | 8e-34 | 36.89% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-26 | 33.76% (234) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 1e-38 | 38.78% (245) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4756 | - | 1e-105 | 69.40% (268) | oxidoreductase |
| M. avium 104 | MAV_0894 | - | 1e-111 | 74.16% (267) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. thermoresistible (build 8) | TH_3505 | - | 1e-114 | 75.37% (268) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0327 | - | 1e-104 | 68.66% (268) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4228 | - | 1e-112 | 74.91% (267) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2424|M.gilvum_PYR-GCK ---MAITAS------DILLTGRVAVVTGGGAGIGRGIAQGLAAFGASVAI
Mvan_4228|M.vanbaalenii_PYR-1 ---MTIAPS------DILLTGRVAVVTGGGAGIGKGIAHGLAAFGASVAI
MSMEG_4850|M.smegmatis_MC2_155 ---MAINPS------DILLTGRVAVVTGGGAGIGRGIAEGLAAFGARVAI
MMAR_4756|M.marinum_M ---MAIDPA------DVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASVAI
MUL_0327|M.ulcerans_Agy99 ---MAIDPA------DVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MAV_0894|M.avium_104 ---MAIDPS------DILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAI
TH_3505|M.thermoresistible__bu ---LTIAPA------DILLTDRVAVVTGGGAGLGRGIAAGFAAFGARVAI
MAB_0833|M.abscessus_ATCC_1997 -MNRETFSR------LFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
Mb1385|M.bovis_AF2122/97 ---MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv ---MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGARVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
* ::**. *:* .:. .. * :.:
Mflv_2424|M.gilvum_PYR-GCK WERDPDTCAAAAAAIG-----GLGLEVDVRDAAAVDTALDRTERELGTVS
Mvan_4228|M.vanbaalenii_PYR-1 WERDPQTCGEAAASVG-----ALGLPTDVRDAEAVQAALERTERELGTVS
MSMEG_4850|M.smegmatis_MC2_155 WERDPETCEAAARAVG-----GVGIVTDVRDADQVDAALAQTTSELGTVS
MMAR_4756|M.marinum_M WERDPQTCAQAAAELG-----GLGIATDVRSGDQVDAALQRTQAELGEVT
MUL_0327|M.ulcerans_Agy99 WERDPQTCAQAAAELG-----GLGIATDVRSGDQVDAALQRTQAELGAVT
MAV_0894|M.avium_104 WERDAQTCTRAAESIG-----GLGIVTDVRDSGQVDTALQRTITELGTPT
TH_3505|M.thermoresistible__bu WERDPDSCARTAEEIG-----ALGIVTDVRDSAAVSAALRQTTEQLGSPT
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
Mb1385|M.bovis_AF2122/97 GDVNLEATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGGLD
Rv1350|M.tuberculosis_H37Rv GDVNLEATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGGLD
MLBr_01807|M.leprae_Br4923 THR---ASVVPDWFFG--------VECDVTDNDAIGAAFKAVEEHQGPVE
: . . : .. . : . . . *
Mflv_2424|M.gilvum_PYR-GCK ILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAAEQT
Mvan_4228|M.vanbaalenii_PYR-1 ILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVGQP
MSMEG_4850|M.smegmatis_MC2_155 ILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAEMP
MMAR_4756|M.marinum_M ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAELP
MUL_0327|M.ulcerans_Agy99 ILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAGLP
MAV_0894|M.avium_104 ILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAG
TH_3505|M.thermoresistible__bu ILVNNAGGTFSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAGQP
MAB_0833|M.abscessus_ATCC_1997 IVVNNAANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVAS-PH
Mb1385|M.bovis_AF2122/97 VMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRER-KR
Rv1350|M.tuberculosis_H37Rv VMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRER-KR
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ-RF
::* *.. . : : . :: :* .: :
Mflv_2424|M.gilvum_PYR-GCK GSVINVTSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPYGIRVNGLA
Mvan_4228|M.vanbaalenii_PYR-1 GSVINITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNALA
MSMEG_4850|M.smegmatis_MC2_155 GSIINLTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNALA
MMAR_4756|M.marinum_M GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNAIA
MUL_0327|M.ulcerans_Agy99 GSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNAIA
MAV_0894|M.avium_104 GSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNAIA
TH_3505|M.thermoresistible__bu GSIVNITSIEGARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNAIA
MAB_0833|M.abscessus_ATCC_1997 AAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNALA
Mb1385|M.bovis_AF2122/97 GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIA
Rv1350|M.tuberculosis_H37Rv GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIA
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
. : : *: . : *:*:*:.::. : : : **. : .* :*
Mflv_2424|M.gilvum_PYR-GCK PDLTMTEGLQKLAFGELSGTVARMVPMRRAGHVDEMASAAVFLASDMASY
Mvan_4228|M.vanbaalenii_PYR-1 PDLTMTEGLQKLAFGDLSGTMADMVPMRRVGHVDEMASAAVFLASDMAAY
MSMEG_4850|M.smegmatis_MC2_155 PDLTVTDGLLALSGGRQPG--GDAIPMKRPGHVDEMAGAAVFLASGMSSY
MMAR_4756|M.marinum_M PDITMTEGLAQLGGAAALERIGSLVPLGRPGDIDEIASVAVFLASDMARY
MUL_0327|M.ulcerans_Agy99 PDITMTEGLAQLGGAAALERIGSLVPLGRPGDVDEIASVAVFLASDMARY
MAV_0894|M.avium_104 PDITLTEGLQQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGY
TH_3505|M.thermoresistible__bu PDIAVTEGLQRMSPDGIPPEVGHAIPLGRPGHVDEIAGAAVFLASEMSSY
MAB_0833|M.abscessus_ATCC_1997 PGAIDTD-MVRKTPPAEVERMANTNHLKRLGLPDEMVGTALLLTSDAGSY
Mb1385|M.bovis_AF2122/97 PGLIRSAMTEAMP-QRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
Rv1350|M.tuberculosis_H37Rv PGLIRSAMTEAMP-QRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMD-SKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGY
*. : : * * .*:.... :*:* . *
Mflv_2424|M.gilvum_PYR-GCK ITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA---
Mvan_4228|M.vanbaalenii_PYR-1 ITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA---
MSMEG_4850|M.smegmatis_MC2_155 ITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG---
MMAR_4756|M.marinum_M VTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MUL_0327|M.ulcerans_Agy99 VTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MAV_0894|M.avium_104 LTGQTLHVDGGTQASSGWYHDPRTGDYRLGPAG--
TH_3505|M.thermoresistible__bu ITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR
MAB_0833|M.abscessus_ATCC_1997 ITGQTIIADGGLVAR--------------------
Mb1385|M.bovis_AF2122/97 MTGTVLDVTGGRFI---------------------
Rv1350|M.tuberculosis_H37Rv MTGTVLDVTGGRFI---------------------
MLBr_01807|M.leprae_Br4923 ISGAVIPVDGGLGMGH-------------------
::* .: . **