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M. thermoresistible (build 8) TH_3954 (-)

annotation: 3-oxoacyl-[acyl-carrier-protein] reductase
coordinates: 377978 - 378712
length: 245

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3954--100% (245)3-oxoacyl-[acyl-carrier-protein] reductase
M. thermoresistible (build 8)TH_3693-8e-7557.55% (245) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4166-5e-4343.39% (242) PUTATIVE oxidoreductase, short chain dehydrogenase/reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1385fabG4e-7154.88% (246) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_4369fabG5e-7155.51% (245) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv1350fabG4e-7154.88% (246) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_02565fabG1e-3838.68% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4443fabG3e-4239.09% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. marinum MMMAR_4033fabG2e-7154.44% (248) 3-oxoacyl-
M. avium 104MAV_5088fabG1e-10879.12% (249) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_2206fabG1e-7156.56% (244) 3-ketoacyl-(acyl-carrier-protein) reductase
M. ulcerans Agy99MUL_3898fabG8e-7055.27% (237) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_1975fabG7e-7256.33% (245) 3-ketoacyl-(acyl-carrier-protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3954|M.thermoresistible__bu      --------------------------------------------------
MAV_5088|M.avium_104                --------------------------------------------------
Mflv_4369|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1975|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2206|M.smegmatis_MC2_155      --------------------------------------------------
Mb1385|M.bovis_AF2122/97            --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4033|M.marinum_M               --------------------------------------------------
MUL_3898|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
MAB_4443|M.abscessus_ATCC_1997      MSPKLTDDLYALLVNSGPGNLLAGRLGIPQPEKLRRYKKGQPALAGPVLI
                                                                                      

TH_3954|M.thermoresistible__bu      --------------------------------------------------
MAV_5088|M.avium_104                --------------------------------------------------
Mflv_4369|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1975|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2206|M.smegmatis_MC2_155      --------------------------------------------------
Mb1385|M.bovis_AF2122/97            --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4033|M.marinum_M               --------------------------------------------------
MUL_3898|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
MAB_4443|M.abscessus_ATCC_1997      GGEGRLAEPLRAALADDYEVVSNNLGGRWADKFGALVFDATGITTPVELK
                                                                                      

TH_3954|M.thermoresistible__bu      --------------------------------------------------
MAV_5088|M.avium_104                --------------------------------------------------
Mflv_4369|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1975|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2206|M.smegmatis_MC2_155      --------------------------------------------------
Mb1385|M.bovis_AF2122/97            --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4033|M.marinum_M               --------------------------------------------------
MUL_3898|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
MAB_4443|M.abscessus_ATCC_1997      ALHEFFTPLLRNVGKSGRLLVIGTTPDKAATTDERIAQRALEGFTRSLAK
                                                                                      

TH_3954|M.thermoresistible__bu      ---------------------------------MPSALLAEK--------
MAV_5088|M.avium_104                ---------------------------------MAESLLLGK--------
Mflv_4369|M.gilvum_PYR-GCK          -----------------------------------MSLLTGQ--------
Mvan_1975|M.vanbaalenii_PYR-1       -----------------------------MRMGEQVSLLTGQ--------
MSMEG_2206|M.smegmatis_MC2_155      -------------------------------------MLTGQ--------
Mb1385|M.bovis_AF2122/97            ----------------------------------MASLLNAR--------
Rv1350|M.tuberculosis_H37Rv         ----------------------------------MASLLNAR--------
MMAR_4033|M.marinum_M               ----------------------------------MSVSLLNG--------
MUL_3898|M.ulcerans_Agy99           ----------------------------------MCGAHRDRGY------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
MAB_4443|M.abscessus_ATCC_1997      EFSNGATVQLVYLHPDAKTGATGLESTVRFILSAKSTYVDGQVFYVGADD
                                                                                      

TH_3954|M.thermoresistible__bu      --------------VAVVTGAGRGIGREIARVLHAHGAEVVLADLDA--D
MAV_5088|M.avium_104                --------------VAVVTGAGQGIGREIARALHRHGARVVLADLDG--S
Mflv_4369|M.gilvum_PYR-GCK          --------------TAVITGGAQGLGFAIAQRFVDEGARVVLGDVNL--E
Mvan_1975|M.vanbaalenii_PYR-1       --------------TAVITGGAQGLGFAIAQRFVEEGARVVLGDVNL--D
MSMEG_2206|M.smegmatis_MC2_155      --------------TAVVTGGAQGLGLAIAKRFISEGARVVLGDLNS--E
Mb1385|M.bovis_AF2122/97            --------------TAVITGGAQGLGLAIGQRFVAEGARVVLGDVNL--E
Rv1350|M.tuberculosis_H37Rv         --------------TAVITGGAQGLGLAIGQRFVAEGARVVLGDVNL--E
MMAR_4033|M.marinum_M               -------------QIAVVTGGAQGLGLAIAERFVSEGARVVLGDVNL--E
MUL_3898|M.ulcerans_Agy99           -------------VYPVVTGGAQGLGLAIAERFVSEGARVVLGDVNL--E
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
MAB_4443|M.abscessus_ATCC_1997      STAPADWDKPLAGKVAIVTGAARGIGETIAEVFARDGAAVVAIDMPS--E
                                                   .::**..:*:*  *.. .  .** **  *:    .

TH_3954|M.thermoresistible__bu      AAAQAAAEVDG-----TGVGCDVTAEDQMKRLVADTVAKHGR-LDLFVNN
MAV_5088|M.avium_104                AARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGG-LDVFVNN
Mflv_4369|M.gilvum_PYR-GCK          ATQEAAEKLGG-ADVAHAVRCDVTSSAEVDALVAAAVDTFGA-LDIMVNN
Mvan_1975|M.vanbaalenii_PYR-1       ATVAAAEKLGG-EDVARAVRCDVTDSAEVDALIAAAVDGFGS-LDIMVNN
MSMEG_2206|M.smegmatis_MC2_155      ATEAAVEELGG-SEVAAAVRCDVTSSADVDALVQAAVERFGG-LDIMVNN
Mb1385|M.bovis_AF2122/97            ATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGG-LDVMVNN
Rv1350|M.tuberculosis_H37Rv         ATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGG-LDVMVNN
MMAR_4033|M.marinum_M               ATEAAAKQLGG-GEVAVAVRCDVTKADEVETLLQTALERFGG-LDIMVNN
MUL_3898|M.ulcerans_Agy99           ATEAAAKQLGG-GEVAVAVRCDVTKADEVETLLQAALERFGG-LDIMVNN
MLBr_02565|M.leprae_Br4923          ALDETANRVGG-----TTLSLDVTADDAVDKITEHLHDYQGGHADILVNN
MAB_4443|M.abscessus_ATCC_1997      ELNELASRVGG-----TALALDVTSEDAVDTITAHLKEHHGGKADILVNN
                                         . .:..       :  ***    :  :        *   *::***

TH_3954|M.thermoresistible__bu      AGITRDASLKRMTVADFDAVVTVHLRGTWLGVREATAVMREQKSGSIVNI
MAV_5088|M.avium_104                AGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTGSIVNM
Mflv_4369|M.gilvum_PYR-GCK          AGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENKRGVIVNM
Mvan_1975|M.vanbaalenii_PYR-1       AGITRDATMRKMTEEQFDQVIAVHLKGTWNGLRAAAAVMREQKRGAIVNM
MSMEG_2206|M.smegmatis_MC2_155      AGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENKRGAIVNM
Mb1385|M.bovis_AF2122/97            AGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNM
Rv1350|M.tuberculosis_H37Rv         AGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNM
MMAR_4033|M.marinum_M               AGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKRGAIVNM
MUL_3898|M.ulcerans_Agy99           AGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKRGAIVNM
MLBr_02565|M.leprae_Br4923          AGITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIVL
MAB_4443|M.abscessus_ATCC_1997      AGITRDKLLKNMDDARWDSVIAVNLLAPQRLTEGLIGNGTIGEGGRVIGL
                                    ******  :  *    :* *: *:* ..    .   .     : * :: :

TH_3954|M.thermoresistible__bu      SSLSGKSGNPGQTNYSAAKAGIIGLTKAAAKEVAHHNVRVNAIQPGLIRT
MAV_5088|M.avium_104                SSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQPGLIRT
Mflv_4369|M.gilvum_PYR-GCK          SSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQPGLIRS
Mvan_1975|M.vanbaalenii_PYR-1       SSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQPGLIRS
MSMEG_2206|M.smegmatis_MC2_155      SSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAIQPGLIRS
Mb1385|M.bovis_AF2122/97            SSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRS
Rv1350|M.tuberculosis_H37Rv         SSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRS
MMAR_4033|M.marinum_M               SSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAIAPGLIRS
MUL_3898|M.ulcerans_Agy99           SSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAIAPGLIRS
MLBr_02565|M.leprae_Br4923          SSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIET
MAB_4443|M.abscessus_ATCC_1997      ASIAGIAGNRGQTNYGATKAGMIGITQALAPSLAEKGITINAVAPGFIET
                                    :*::*  *  *****.::***::*:*:* :  :*  .: :**: **:*.:

TH_3954|M.thermoresistible__bu      PMTETMPAEVFAEREAAVPMKRAGEPAEVAGAVVFLGSDLSSYITGSVIE
MAV_5088|M.avium_104                PMTAAMPPDVFAEREAAVPMKRAGEPEEVAGAVVFLASELSSYITGTVLG
Mflv_4369|M.gilvum_PYR-GCK          AMTEAMPQRIWDSKVAEVPLGRAGEPDEVAKVALFLASDLSSYMTGTVLE
Mvan_1975|M.vanbaalenii_PYR-1       AMTEAMPQRIWDSKVAEVPMGRAGEPEEVANVALFLASDLSSYMTGTVLE
MSMEG_2206|M.smegmatis_MC2_155      AMTEAMPQRIWDEKLAEIPMGRAGEPDEVAKVALFLASDLSSYMTGTVLE
Mb1385|M.bovis_AF2122/97            AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSYMTGTVLD
Rv1350|M.tuberculosis_H37Rv         AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSYMTGTVLD
MMAR_4033|M.marinum_M               AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSYMTGTVLD
MUL_3898|M.ulcerans_Agy99           AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSYMTGTVLD
MLBr_02565|M.leprae_Br4923          QMTAAIPLATREVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTGNVIR
MAB_4443|M.abscessus_ATCC_1997      KMTAAIPLANREVGRRINSLNQGGEPVDVAETIAYFASPASNAVTGNVVR
                                     ** ::*           .: :.* * :** .  ::.   *. :**.*: 

TH_3954|M.thermoresistible__bu      VGGGRYM--
MAV_5088|M.avium_104                VGGGRYM--
Mflv_4369|M.gilvum_PYR-GCK          VTGGRHL--
Mvan_1975|M.vanbaalenii_PYR-1       VTGGRHL--
MSMEG_2206|M.smegmatis_MC2_155      VTGGRHV--
Mb1385|M.bovis_AF2122/97            VTGGRFI--
Rv1350|M.tuberculosis_H37Rv         VTGGRFI--
MMAR_4033|M.marinum_M               VTGGRFI--
MUL_3898|M.ulcerans_Agy99           VTGGRFI--
MLBr_02565|M.leprae_Br4923          VCGQAMLGA
MAB_4443|M.abscessus_ATCC_1997      VCGQSWLGA
                                    * *   :