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M. thermoresistible (build 8) TH_1753 (-)

annotation: major facilitator superfamily protein MFS_1, putative
coordinates: 3375194 - 3376540
length: 449

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1753--100% (449)major facilitator superfamily protein MFS_1, putative
M. thermoresistible (build 8)TH_1317-4e-2024.20% (376) transmembrane transport protein
M. thermoresistible (build 8)TH_1986-6e-1625.07% (383) tetracycline-resistance determinant TetV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1288c-3e-1425.00% (360) integral membrane transport protein
M. gilvum PYR-GCKMflv_1033-1e-15871.43% (399) major facilitator transporter
M. tuberculosis H37RvRv1258c-3e-1425.00% (360) integral membrane transport protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0880-1e-2926.75% (400) hypothetical protein MAB_0880
M. marinum MMMAR_4182-5e-1624.65% (361) hypothetical protein MMAR_4182
M. avium 104MAV_0138-9e-1426.70% (412) transporter, major facilitator family protein
M. smegmatis MC2 155MSMEG_1329-1e-16570.42% (409) major facilitator superfamily protein MFS_1, putative
M. ulcerans Agy99MUL_0354-1e-0827.62% (210) integral membrane protein
M. vanbaalenii PYR-1Mvan_5800-1e-16571.67% (413) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1033|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5800|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155      --------------------------------------------------
TH_1753|M.thermoresistible__bu      --------------------------------------------------
Mb1288c|M.bovis_AF2122/97           --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4182|M.marinum_M               --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
MUL_0354|M.ulcerans_Agy99           MLTSGSMTTTATIAAGEAMRVSSSSSPDLPDAGDTTKFLRPRNAALRSKA
                                                                                      

Mflv_1033|M.gilvum_PYR-GCK          -----------MIQSPSRPAPVTSLPARGAFGLMFDRVFGALFWGKMFAV
Mvan_5800|M.vanbaalenii_PYR-1       ---------------MTAEATAARLPARNALGLMFDPVFGALFWGKIFAV
MSMEG_1329|M.smegmatis_MC2_155      ---------------MTADAPAR---PRNALRLMFDPVFGALFWGKIFSV
TH_1753|M.thermoresistible__bu      ---------VSTSPATTTTAATDPAPPRGALGLMFDPVFGGLFWGKILSV
Mb1288c|M.bovis_AF2122/97           --------------------------MRNSN---RGPAF-LILFATLMAA
Rv1258c|M.tuberculosis_H37Rv        --------------------------MRNSN---RGPAF-LILFATLMAA
MMAR_4182|M.marinum_M               --------------------------MRNSS---RGPAF-LILFATLAAC
MAB_0880|M.abscessus_ATCC_1997      -----------------------MADRGGIFVSLRTRNYRLWISGQMVSL
MAV_0138|M.avium_104                -------------MMSSNVRAARNRPGRTDPQPPTGAPLFVGVLGLLLAT
MUL_0354|M.ulcerans_Agy99           RGGSRSAARMANTKTNRKPRSARALCARAVAAPLGGARPLGERAGGRHRP
                                                                                .     

Mflv_1033|M.gilvum_PYR-GCK          VAVWTHGLVAAIVMYDA-TRSALMVGLVGVAQFFPQLILAPTSGKWADTG
Mvan_5800|M.vanbaalenii_PYR-1       VAVWTHGIVAAIVMYDA-TRSALMVGMVGVVQFAPQLILSPTSGKWADTG
MSMEG_1329|M.smegmatis_MC2_155      VAVWTHGIVAAIVMYDA-TRSAVMVGMVGVAQFLPQLILSPTSGKWADVG
TH_1753|M.thermoresistible__bu      VAVWTHGIVAAITMFNA-TGSAVMVGLVGVAQFGPQLILTPISGKWADVG
Mb1288c|M.bovis_AF2122/97           AGDGVSIVAFPWLVLQR-EGSAGQASIVASATMLPLLFATLVAGTAVDYF
Rv1258c|M.tuberculosis_H37Rv        AGDGVSIVAFPWLVLQR-EGSAGQASIVASATMLPLLFATLVAGTAVDYF
MMAR_4182|M.marinum_M               AGNGISIVAFPWLVLER-EGSAGQASIVAGAITLPLLFSTLVAGTAVDYF
MAB_0880|M.abscessus_ATCC_1997      IGTWMQRVAQDWLVLDLSHGNAFLLGVVMALQFGPTLLLSVWGGMLADRY
MAV_0138|M.avium_104                GWVANHFVGLMPAISDRDHLATTTLDGIFGIYALGLLPGLLVGGRTSDAL
MUL_0354|M.ulcerans_Agy99           AREGYPAVIWLLLGGNLVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLAAF
                                           :       :     :     .               *      

Mflv_1033|M.gilvum_PYR-GCK          NP---ARQILLGRVFCVIGSGSIAVWMFAEPG-----LQGVAVAIPILIG
Mvan_5800|M.vanbaalenii_PYR-1       NP---ARQILLGRVLCVAGSGSIAAWMFVQPG-----LTGLAAAVPVLLG
MSMEG_1329|M.smegmatis_MC2_155      NP---ARQILLGRLMCIAGSGSTAAWMALAPD-----LTGNAVAVPVLVG
TH_1753|M.thermoresistible__bu      NQ---ARQILLGRLLCTAGSGLIAAWLFLSPH-----MQGVAVAVPILIG
Mb1288c|M.bovis_AF2122/97           GR---RRVSMVADALSGA---AVAGVPLVAWG-----YGGDAVNVLVLAV
Rv1258c|M.tuberculosis_H37Rv        GR---RRVSMVADALSGA---AVAGVPLVAWG-----YGGDAVNVLVLAV
MMAR_4182|M.marinum_M               GR---RPVSMVSDALSGS---AVAIVPLIAWA-----FGDDAVSVAVLAA
MAB_0880|M.abscessus_ATCC_1997      DK---RRMLMLTQALMAL-----FALTVGLLQ-----VTGLVRIWHVMAV
MAV_0138|M.avium_104                GR---RPVALTG----------SAAALVGTVA-----MLLSQHSPALFAG
MUL_0354|M.ulcerans_Agy99           GVGWAVGQLVCGWLVDSLGPRATLAWTMTIAAGVLVGMAEARSVAALLVG
                                    .        :                                    ::  

Mflv_1033|M.gilvum_PYR-GCK          TTLVGIGFVVGGP-AMQSIVPTLIRNG--ELPTAMALNSLPMTVGRVIGP
Mvan_5800|M.vanbaalenii_PYR-1       TTLVGFGFVVGGP-AMQSIVPNLIRAG--ELPTAMALNSIPMTIGRIIGP
MSMEG_1329|M.smegmatis_MC2_155      ATLVGFGFVIGGP-AMQSVVPNLIREG--ELATAMALNSIPMTIGRILGP
TH_1753|M.thermoresistible__bu      TTLVGFGFVVGGP-AMQSIVPSLIRPG--ELSTAMALNSLPMTVGRIAGP
Mb1288c|M.bovis_AF2122/97           LAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGP
Rv1258c|M.tuberculosis_H37Rv        LAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGP
MMAR_4182|M.marinum_M               LGACSATFDPAGITARQSMLPEAAARAGWSLDRINSSYEAILNLAFVVGP
MAB_0880|M.abscessus_ATCC_1997      AFAMGCAAAIEAP-TRQSFTIEMVGPE--HLPNAVGLNSMVFNLAGIIGP
MAV_0138|M.avium_104                RLIVGLGVGLAIS-AGTAWASDLRGPAG------AATAGAVLTAGFAVGP
MUL_0354|M.ulcerans_Agy99           AMITGVVYDAPRP-VMGAAIAELIPEPSRRAKLDAWRFGWIVSIGRAITG
                                        .         .  :                       .. .     

Mflv_1033|M.gilvum_PYR-GCK          AAGAYLAAH--VGPATAFTVSAVLH-----LVFAMFLLAVRFPAPPQRRP
Mvan_5800|M.vanbaalenii_PYR-1       AAGAYLAAH--IGPATAFAVSTVLH-----LVFAFFLLAVRFPAPPERRA
MSMEG_1329|M.smegmatis_MC2_155      PIGAYLAAH--LGAAAGFAISAGLH-----VIFAVFLVLVTFPTRPKLDP
TH_1753|M.thermoresistible__bu      AVGAYIAAS--FGAPTAFAVSCVLH-----LLFALILVALPFPAQTPQPA
Mb1288c|M.bovis_AF2122/97           AIGGLMIAT--VGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQ
Rv1258c|M.tuberculosis_H37Rv        AIGGLMIAT--VGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQ
MMAR_4182|M.marinum_M               GIGGLMIAT--VGGITTMWITAGAFGLSLLAIGALRLEGAGRPHHETRPD
MAB_0880|M.abscessus_ATCC_1997      ATSGVLIGL--IGTGWVFLLNFVSF---IAVGIALWRMRPGELHSSEPIP
MAV_0138|M.avium_104                FAGGVLAWAGPSGVRASFALAAAIL-----ALAAFAVVAAPQPSPVTAPA
MUL_0354|M.ulcerans_Agy99           GVGGLLAAWS--GVPVLFWINAVAC--ALLALVAARCIPATAHRPPVAPA
                                      .. :      *    : :             *                

Mflv_1033|M.gilvum_PYR-GCK          GADYRVRAAVRYVLADRPL-LLALLAVTTVGIVSDPSITLAPSMADELGG
Mvan_5800|M.vanbaalenii_PYR-1       GTDYRVRVAVRYVLRDRPL-LLALVAVTTVGIVSDPSITLTPSMADELGG
MSMEG_1329|M.smegmatis_MC2_155      DGDYRVRAALRHVWRDRPL-LLALLAVSTVGFASDPSITLTPSMAEDLGG
TH_1753|M.thermoresistible__bu      GTDYRVRTALRHVWRDRPL-LLALLAVTTVGFASDPSITLAPSLADNLGG
Mb1288c|M.bovis_AF2122/97           GLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQ
Rv1258c|M.tuberculosis_H37Rv        GLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQ
MMAR_4182|M.marinum_M               GLVSGVTQGLRFVWNLRVLRALALIDLTVTALYLPMESVLFPTYFSDRQQ
MAB_0880|M.abscessus_ATCC_1997      AAKGQLRQGFSYVWRRRDLFMIMLTVFLVSTFGLNFSLTLAVLARETFGR
MAV_0138|M.avium_104                DPDGEETADAAPQGISRALSWAMPLAPWVFASATLGFVTIPGRLHTALAA
MUL_0354|M.ulcerans_Agy99           VHVRAAHNSYRRAFSDGRLVLLFASSLATLTAVRGLYATVPMLMADSGLG
                                                      *         .         .:          

Mflv_1033|M.gilvum_PYR-GCK          GAAMVGTLSAVFGVGAALGMGSLAVLRGRIASAYVSSIGMVALT-----L
Mvan_5800|M.vanbaalenii_PYR-1       GASLVGTLSAVFGVGAAVGMTALALLRGRIGSAVVSSIGMAALA-----A
MSMEG_1329|M.smegmatis_MC2_155      GTQLVGALSASFGVGAAVGMIVLAVLRGRIASERVSSVGLFLLT-----A
TH_1753|M.thermoresistible__bu      GSELVGALSAAFGIGAAAGMATLALLRGRLASARVSVIGLWLLG-----A
Mb1288c|M.bovis_AF2122/97           -PVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLG-----L
Rv1258c|M.tuberculosis_H37Rv        -PVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLG-----L
MMAR_4182|M.marinum_M               -PAQLGSVLVALSLGSLVGALGYGMLSNYVSRRTIMLTAVLTLG-----A
MAB_0880|M.abscessus_ATCC_1997      GAESYGLLSTALAIGTLLGAT-FAARRTKKVRMTLFYGAAMAFG-----L
MAV_0138|M.avium_104                PVAAGTATLIVNGVSGAVQVLARALRWGPQAGTAGAVLAALGYA-----V
MUL_0354|M.ulcerans_Agy99           AGEFGWAQVANAAAGIGLTPVITPWLGRKVAARINPRLDILAIAGGWTAL
                                                . .                                   

Mflv_1033|M.gilvum_PYR-GCK          GSAVLAVGMQSWIAYTGFALAGFGFGCAMTGLSTVVQERAPEELRGRIMA
Mvan_5800|M.vanbaalenii_PYR-1       GSAILAVAMEPWVALTGFAVSGFGFGCAMTGLSTVVQERAPEELRGRIMA
MSMEG_1329|M.smegmatis_MC2_155      GSALLAAATEAPVALIGFAIAGLGFGWSMTGLSTVVQERAPEELRGRIMA
TH_1753|M.thermoresistible__bu      GSLVLALSTVTAVALAGFVVAGVGFGWAMTGLSTVVQERAPDELRGRIMA
Mb1288c|M.bovis_AF2122/97           ASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVG
Rv1258c|M.tuberculosis_H37Rv        ASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVG
MMAR_4182|M.marinum_M               ATTGIALLPPLPVILVLCALIGVVYGPIQPIYNYVMQTRAPHYLRGRVVG
MAB_0880|M.abscessus_ATCC_1997      SEVVVSVMPTYLSVALALVPAGLLALTFTTSAMNIIQLSVDSQLRGRVMG
MAV_0138|M.avium_104                AAAAPSTLTP-ALGVPLFVVLGCASGLCLREGLIDLEAAAPQRLRGGLTG
MUL_0354|M.ulcerans_Agy99           TMAGAALAHTTFGFAIAVAASAAGEIAWFVIAVGTVHRIAPPASGGRYHG
                                         :            .  .             :.  .     *   .

Mflv_1033|M.gilvum_PYR-GCK          LWLVGFLGSRPIAAAVLGGTADLTNVFVAFAVASGLALVVTVLCRPSKLV
Mvan_5800|M.vanbaalenii_PYR-1       LWLVGFLGSRPIAAAVLGGTADVLSVYAAFAVAAALSLAVTLLCRPAKLV
MSMEG_1329|M.smegmatis_MC2_155      LWLVGFLGSRPFAAALLGGAADVFNVRVAFLIAAAATFALALAARPATMS
TH_1753|M.thermoresistible__bu      LWLVGFLGSRPIAAAVLGGTADTISVAAAFALAALSVAVIAVLCRPATLG
Mb1288c|M.bovis_AF2122/97           VMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPAL
Rv1258c|M.tuberculosis_H37Rv        VMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPAL
MMAR_4182|M.marinum_M               VMTSLAYAAGPLGLLLAGPVADAAGLKVAFFALALPIAITGLMCIRLPSL
MAB_0880|M.abscessus_ATCC_1997      IYMVAFLGGTPLGSPLVGWLADLHGGRMPLLVGGLVSAAAGLVCATYLHR
MAV_0138|M.avium_104                LFYVVTYIGFGLPLILASVRPGVATAILSGMAVLAVTAAVGRAARLRRDD
MUL_0354|M.ulcerans_Agy99           IWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALCLPLNRS
                                    :       .  .   : .                         .      

Mflv_1033|M.gilvum_PYR-GCK          DLR---------------------------------
Mvan_5800|M.vanbaalenii_PYR-1       GPIPD-------------------------------
MSMEG_1329|M.smegmatis_MC2_155      APIPASV-----------------------------
TH_1753|M.thermoresistible__bu      RPAPFEPVPVGGGSTGADRARSNMVVTNPAEL----
Mb1288c|M.bovis_AF2122/97           RELDLAPQADIDRPVGSAQ-----------------
Rv1258c|M.tuberculosis_H37Rv        RELDLAPQADIDRPVGSAQ-----------------
MMAR_4182|M.marinum_M               RELDHAPTQDISETSLL-------------------
MAB_0880|M.abscessus_ATCC_1997      HPCPVVAGEVPEADDMVPPAPAATPVCEPTPLARRS
MAV_0138|M.avium_104                HRQN--------------------------------
MUL_0354|M.ulcerans_Agy99           GDVGVRDSQYTAVAAAA-------------------