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MTAEATAARLPARNALGLMFDPVFGALFWGKIFAVVAVWTHGIVAAIVMYDATRSALMVGMVGVVQFAPQ LILSPTSGKWADTGNPARQILLGRVLCVAGSGSIAAWMFVQPGLTGLAAAVPVLLGTTLVGFGFVVGGPA MQSIVPNLIRAGELPTAMALNSIPMTIGRIIGPAAGAYLAAHIGPATAFAVSTVLHLVFAFFLLAVRFPA PPERRAGTDYRVRVAVRYVLRDRPLLLALVAVTTVGIVSDPSITLTPSMADELGGGASLVGTLSAVFGVG AAVGMTALALLRGRIGSAVVSSIGMAALAAGSAILAVAMEPWVALTGFAVSGFGFGCAMTGLSTVVQERA PEELRGRIMALWLVGFLGSRPIAAAVLGGTADVLSVYAAFAVAAALSLAVTLLCRPAKLVGPIPD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5800 | - | - | 100% (415) | major facilitator superfamily transporter |
| M. vanbaalenii PYR-1 | Mvan_1167 | - | 1e-33 | 27.95% (390) | protein of unknown function DUF894, DitE |
| M. vanbaalenii PYR-1 | Mvan_4580 | - | 9e-15 | 24.68% (389) | H+ antiporter protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 2e-11 | 24.31% (362) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1033 | - | 0.0 | 82.51% (406) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1258c | - | 2e-11 | 24.31% (362) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0880 | - | 2e-26 | 24.74% (384) | hypothetical protein MAB_0880 |
| M. marinum M | MMAR_0333 | - | 5e-14 | 22.73% (396) | hypothetical protein MMAR_0333 |
| M. avium 104 | MAV_0138 | - | 1e-11 | 30.79% (315) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_1329 | - | 1e-169 | 73.67% (414) | major facilitator superfamily protein MFS_1, putative |
| M. thermoresistible (build 8) | TH_1753 | - | 1e-165 | 71.67% (413) | major facilitator superfamily protein MFS_1, putative |
| M. ulcerans Agy99 | MUL_0354 | - | 2e-07 | 27.95% (161) | integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5800|M.vanbaalenii_PYR-1 -------------MTAEATAARLPARNALGLMFDPVFGALFWGKIFAVVA
Mflv_1033|M.gilvum_PYR-GCK ---------MIQSPSRPAPVTSLPARGAFGLMFDRVFGALFWGKMFAVVA
MSMEG_1329|M.smegmatis_MC2_155 ----------------MTADAPARPRNALRLMFDPVFGALFWGKIFSVVA
TH_1753|M.thermoresistible__bu -------VSTSPATTTTAATDPAPPRGALGLMFDPVFGGLFWGKILSVVA
Mb1288c|M.bovis_AF2122/97 -------------------MRNSNRGPAFLILFATLMAAAGDG-------
Rv1258c|M.tuberculosis_H37Rv -------------------MRNSNRGPAFLILFATLMAAAGDG-------
MAB_0880|M.abscessus_ATCC_1997 ---------------------MADRGGIFVSLRTRNYRLWISGQMVSLIG
MAV_0138|M.avium_104 -----------MMSSNVRAARNRPGRTDPQPPTGAPLFVGVLGLLLATGW
MMAR_0333|M.marinum_M --------------MALAATRKLVRDPQLRRLMAVCATFLTSN-------
MUL_0354|M.ulcerans_Agy99 MLTSGSMTTTATIAAGEAMRVSSSSSPDLPDAGDTTKFLRPRNAALRSKA
.
Mvan_5800|M.vanbaalenii_PYR-1 VWTHGIVAAIVMYDA-TRSALMVGMVGVVQFAPQLILSPTSGKWADTGNP
Mflv_1033|M.gilvum_PYR-GCK VWTHGLVAAIVMYDA-TRSALMVGLVGVAQFFPQLILAPTSGKWADTGNP
MSMEG_1329|M.smegmatis_MC2_155 VWTHGIVAAIVMYDA-TRSAVMVGMVGVAQFLPQLILSPTSGKWADVGNP
TH_1753|M.thermoresistible__bu VWTHGIVAAITMFNA-TGSAVMVGLVGVAQFGPQLILTPISGKWADVGNQ
Mb1288c|M.bovis_AF2122/97 --VSIVAFPWLVLQR-EGSAGQASIVASATMLPLLFATLVAGTAVDYFGR
Rv1258c|M.tuberculosis_H37Rv --VSIVAFPWLVLQR-EGSAGQASIVASATMLPLLFATLVAGTAVDYFGR
MAB_0880|M.abscessus_ATCC_1997 TWMQRVAQDWLVLDLSHGNAFLLGVVMALQFGPTLLLSVWGGMLADRYDK
MAV_0138|M.avium_104 VANHFVGLMPAISDRDHLATTTLDGIFGIYALGLLPGLLVGGRTSDALGR
MMAR_0333|M.marinum_M ---SAHGVLLTVFAFSVGGAATVGVVTLVRMLPSALLAPLAATLATSPRP
MUL_0354|M.ulcerans_Agy99 RGGSRSAARMANTKTNRKPRSARALCARAVAAPLGGARPLGERAGGRHRP
.
Mvan_5800|M.vanbaalenii_PYR-1 ARQILLGRVLCVAGSG--SIAAWMFVQPGLTGLAAAVPVLLGTTLVGFGF
Mflv_1033|M.gilvum_PYR-GCK ARQILLGRVFCVIGSG--SIAVWMFAEPGLQGVAVAIPILIGTTLVGIGF
MSMEG_1329|M.smegmatis_MC2_155 ARQILLGRLMCIAGSG--STAAWMALAPDLTGNAVAVPVLVGATLVGFGF
TH_1753|M.thermoresistible__bu ARQILLGRLLCTAGSG--LIAAWLFLSPHMQGVAVAVPILIGTTLVGFGF
Mb1288c|M.bovis_AF2122/97 RRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGM
Rv1258c|M.tuberculosis_H37Rv RRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGM
MAB_0880|M.abscessus_ATCC_1997 RRMLMLTQALM-------ALFALTVGLLQVTGLVRIWHVMAVAFAMGCAA
MAV_0138|M.avium_104 RPVALTG------------SAAALVGTVAMLLSQHSPALFAGRLIVGLGV
MMAR_0333|M.marinum_M QVHLAIGVGARG-------MTTIATVIVVVSGAPLGVVLVVLGVDSLMSA
MUL_0354|M.ulcerans_Agy99 AREGYPAVIWLLLGGN-LVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLAA
. : .
Mvan_5800|M.vanbaalenii_PYR-1 VVGGPAMQSIVPNLIRAGELPTAMALNSIPMTIGRIIGPAAGAYLAAHIG
Mflv_1033|M.gilvum_PYR-GCK VVGGPAMQSIVPTLIRNGELPTAMALNSLPMTVGRVIGPAAGAYLAAHVG
MSMEG_1329|M.smegmatis_MC2_155 VIGGPAMQSVVPNLIREGELATAMALNSIPMTIGRILGPPIGAYLAAHLG
TH_1753|M.thermoresistible__bu VVGGPAMQSIVPSLIRPGELSTAMALNSLPMTVGRIAGPAVGAYIAASFG
Mb1288c|M.bovis_AF2122/97 TARDSMLPEAAARAGWS--LDRINGAYEAILNLAFIVGPAIGGLMIATVG
Rv1258c|M.tuberculosis_H37Rv TARDSMLPEAAARAGWS--LDRINGAYEAILNLAFIVGPAIGGLMIATVG
MAB_0880|M.abscessus_ATCC_1997 AIEAPTRQSFTIEMVGPEHLPNAVGLNSMVFNLAGIIGPATSGVLIGLIG
MAV_0138|M.avium_104 GLAISAGTAWASDLRGPAGAATAGAVLTAGFAVGPFAGGVL--AWAGPSG
MMAR_0333|M.marinum_M AVRSLHAALVVRLATSVAEAATANAATGVLLYASALAGPALAGVMLAFVG
MUL_0354|M.ulcerans_Agy99 FGVGWAVGQLVCGWLVDSLGPRATLAWTMTIAAGVLVGMAEARSVAALLV
. : . . * .
Mvan_5800|M.vanbaalenii_PYR-1 PATAFAVSTVLH-----LVFAFFLLAVRFPAPPERRAGTDYRVRVAVRYV
Mflv_1033|M.gilvum_PYR-GCK PATAFTVSAVLH-----LVFAMFLLAVRFPAPPQRRPGADYRVRAAVRYV
MSMEG_1329|M.smegmatis_MC2_155 AAAGFAISAGLH-----VIFAVFLVLVTFPTRPKLDPDGDYRVRAALRHV
TH_1753|M.thermoresistible__bu APTAFAVSCVLH-----LLFALILVALPFPAQTPQPAGTDYRVRTALRHV
Mb1288c|M.bovis_AF2122/97 GITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFV
Rv1258c|M.tuberculosis_H37Rv GITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFV
MAB_0880|M.abscessus_ATCC_1997 TGWVFLLNFVSF---IAVGIALWRMRPGELHSSEPIPAAKGQLRQGFSYV
MAV_0138|M.avium_104 VRASFALAAAIL-----ALAAFAVVAAPQPSPVTAPADPDGEETADAAPQ
MMAR_0333|M.marinum_M VGWALTLPAALFVVGALTALRITVAPIDDMPDTGGARPSGGVARVQLRAV
MUL_0354|M.ulcerans_Agy99 GAMITGVVYDAP---RPVMGAAIAELIPEPSRRAKLDAWRFGWIVSIGRA
:
Mvan_5800|M.vanbaalenii_PYR-1 LR--------DRPL-LLALVAVTTVGIVSDPSITLTPSMADELGGGASLV
Mflv_1033|M.gilvum_PYR-GCK LA--------DRPL-LLALLAVTTVGIVSDPSITLAPSMADELGGGAAMV
MSMEG_1329|M.smegmatis_MC2_155 WR--------DRPL-LLALLAVSTVGFASDPSITLTPSMAEDLGGGTQLV
TH_1753|M.thermoresistible__bu WR--------DRPL-LLALLAVTTVGFASDPSITLAPSLADNLGGGSELV
Mb1288c|M.bovis_AF2122/97 WN--------LRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLG
Rv1258c|M.tuberculosis_H37Rv WN--------LRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLG
MAB_0880|M.abscessus_ATCC_1997 WR--------RRDLFMIMLTVFLVSTFGLNFSLTLAVLARETFGRGAESY
MAV_0138|M.avium_104 GI--------SRALSWAMPLAPWVFASATLGFVTIPGRLHTALAAPVAAG
MMAR_0333|M.marinum_M GAGFRAIIESRPAAAAATLFLLTTTLLDGFWYVASAPLAADQFGLGPSGV
MUL_0354|M.ulcerans_Agy99 ITG-------GVGGLLAAWSGVPVLFWINAVACALLALVAARCIPATAHR
. .
Mvan_5800|M.vanbaalenii_PYR-1 GTLSAVFGVGAAVGMTALALLRGRIGSAVVSSIGMAALA--AGSAILAVA
Mflv_1033|M.gilvum_PYR-GCK GTLSAVFGVGAALGMGSLAVLRGRIASAYVSSIGMVALT--LGSAVLAVG
MSMEG_1329|M.smegmatis_MC2_155 GALSASFGVGAAVGMIVLAVLRGRIASERVSSVGLFLLT--AGSALLAAA
TH_1753|M.thermoresistible__bu GALSAAFGIGAAAGMATLALLRGRLASARVSVIGLWLLG--AGSLVLALS
Mb1288c|M.bovis_AF2122/97 WALMAIAG-GGLVGALGYAVLAIRVPRRVTMSTAVLTLG--LASMVIAFL
Rv1258c|M.tuberculosis_H37Rv WALMAIAG-GGLVGALGYAVLAIRVPRRVTMSTAVLTLG--LASMVIAFL
MAB_0880|M.abscessus_ATCC_1997 GLLSTALAIGTLLGAT-FAARRTKKVRMTLFYGAAMAFG--LSEVVVSVM
MAV_0138|M.avium_104 TATLIVNGVSGAVQVLARALRWGPQAGTAGAVLAALGYA--VAAAAPSTL
MMAR_0333|M.marinum_M TTIMTIYGVGGLLGAVAMLSIAGRGGLARMFTLARLSEA--LLLAAIGAA
MUL_0354|M.ulcerans_Agy99 PPVAPAVHVRAAHNSYRRAFSDGRLVLLFASSLATLTAVRGLYATVPMLM
.
Mvan_5800|M.vanbaalenii_PYR-1 MEPWVALTGFAVSGFGFGCAMTGLSTVVQERAPEELRGRIMALWLVGFLG
Mflv_1033|M.gilvum_PYR-GCK MQSWIAYTGFALAGFGFGCAMTGLSTVVQERAPEELRGRIMALWLVGFLG
MSMEG_1329|M.smegmatis_MC2_155 TEAPVALIGFAIAGLGFGWSMTGLSTVVQERAPEELRGRIMALWLVGFLG
TH_1753|M.thermoresistible__bu TVTAVALAGFVVAGVGFGWAMTGLSTVVQERAPDELRGRIMALWLVGFLG
Mb1288c|M.bovis_AF2122/97 PPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYA
Rv1258c|M.tuberculosis_H37Rv PPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYA
MAB_0880|M.abscessus_ATCC_1997 PTYLSVALALVPAGLLALTFTTSAMNIIQLSVDSQLRGRVMGIYMVAFLG
MAV_0138|M.avium_104 TP-ALGVPLFVVLGCASGLCLREGLIDLEAAAPQRLRGGLTGLFYVVTYI
MMAR_0333|M.marinum_M SLPALGLVLAAGVGGGSAASWAIAPTLVQRSVNRASMVTAAASLQSVSQL
MUL_0354|M.ulcerans_Agy99 ADSGLGAGEFGWAQVANAAAGIGLTPVITPWLGRKVAARINPRLDILAIA
:
Mvan_5800|M.vanbaalenii_PYR-1 SRPIAAAVLGGTADVLSVYAAFAVAAALSLAVTLLCRPAKLVGPIPD---
Mflv_1033|M.gilvum_PYR-GCK SRPIAAAVLGGTADLTNVFVAFAVASGLALVVTVLCRPSKLVDLR-----
MSMEG_1329|M.smegmatis_MC2_155 SRPFAAALLGGAADVFNVRVAFLIAAAATFALALAARPATMSAPIPASV-
TH_1753|M.thermoresistible__bu SRPIAAAVLGGTADTISVAAAFALAALSVAVIAVLCRPATLGRPAPFEPV
Mb1288c|M.bovis_AF2122/97 AGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQ
Rv1258c|M.tuberculosis_H37Rv AGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQ
MAB_0880|M.abscessus_ATCC_1997 GTPLGSPLVGWLADLHGGRMPLLVGGLVSAAAGLVCATYLHRHPCPVVAG
MAV_0138|M.avium_104 GFGLPLILASVRPGVATAILSGMAVLAVTAAVGRAARLRRDDHRQN----
MMAR_0333|M.marinum_M AIAAGAGIAAVLVGSLGLTGALAIVSGAAALITVLAWPQVRRADKLSDDD
MUL_0354|M.ulcerans_Agy99 GGWTALTMAGAALAHTTFGFAIAVAASAAGEIAWFVIAVGTVHRIAPPAS
. : . .
Mvan_5800|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1033|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155 --------------------------------------------------
TH_1753|M.thermoresistible__bu PVGGGSTGADRARSNMVVTNPAEL--------------------------
Mb1288c|M.bovis_AF2122/97 ADIDRPVGSAQ---------------------------------------
Rv1258c|M.tuberculosis_H37Rv ADIDRPVGSAQ---------------------------------------
MAB_0880|M.abscessus_ATCC_1997 EVPEADDMVPPAPAATPVCEPTPLARRS----------------------
MAV_0138|M.avium_104 --------------------------------------------------
MMAR_0333|M.marinum_M SAKLAVIRATPVLAPLPALALEQLARTATRMAVPAGSDVIRQGDRGDRFY
MUL_0354|M.ulcerans_Agy99 GGRYHGIWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALC
Mvan_5800|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1033|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155 --------------------------------------------------
TH_1753|M.thermoresistible__bu --------------------------------------------------
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0138|M.avium_104 --------------------------------------------------
MMAR_0333|M.marinum_M MIASGLADATVNGRRVATLGPGGSFGEIALLHDVARSATVTARKDLDLVA
MUL_0354|M.ulcerans_Agy99 LPLNRSGDVGVRDSQYTAVAAAA---------------------------
Mvan_5800|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1033|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155 --------------------------------------------------
TH_1753|M.thermoresistible__bu --------------------------------------------------
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0138|M.avium_104 --------------------------------------------------
MMAR_0333|M.marinum_M VDRAEFLAALSSNTAAGLRLGGLARTRLGTVPVEERLIELGPDPALNSQS
MUL_0354|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5800|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1033|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155 --------------------------------------------------
TH_1753|M.thermoresistible__bu --------------------------------------------------
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0138|M.avium_104 --------------------------------------------------
MMAR_0333|M.marinum_M LSELLAAQPALAGIGDGALRELADTAKVLAAPDGALITCEGDHGDTYYVI
MUL_0354|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5800|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1033|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1329|M.smegmatis_MC2_155 --------------------------------------------------
TH_1753|M.thermoresistible__bu --------------------------------------------------
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0138|M.avium_104 --------------------------------------------------
MMAR_0333|M.marinum_M LEGAAQVLDDGTAVHHLGPGEGFGEQAILRDVPRTATVRAVGDTTLVAVD
MUL_0354|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5800|M.vanbaalenii_PYR-1 ---------
Mflv_1033|M.gilvum_PYR-GCK ---------
MSMEG_1329|M.smegmatis_MC2_155 ---------
TH_1753|M.thermoresistible__bu ---------
Mb1288c|M.bovis_AF2122/97 ---------
Rv1258c|M.tuberculosis_H37Rv ---------
MAB_0880|M.abscessus_ATCC_1997 ---------
MAV_0138|M.avium_104 ---------
MMAR_0333|M.marinum_M REAFQRARR
MUL_0354|M.ulcerans_Agy99 ---------