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M. thermoresistible (build 8) TH_1317 (-)

annotation: transmembrane transport protein
coordinates: 2504346 - 2505896
length: 517

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1317--100% (517)transmembrane transport protein
M. thermoresistible (build 8)TH_1986-4e-2430.00% (270) tetracycline-resistance determinant TetV
M. thermoresistible (build 8)TH_2406-2e-2025.00% (412) PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1288c-4e-1722.25% (409) integral membrane transport protein
M. gilvum PYR-GCKMflv_5163-0.068.18% (506) protein of unknown function DUF894, DitE
M. tuberculosis H37RvRv1258c-4e-1722.25% (409) integral membrane transport protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0880-9e-4432.38% (420) hypothetical protein MAB_0880
M. marinum MMMAR_4182-8e-1923.40% (406) hypothetical protein MMAR_4182
M. avium 104MAV_1406-7e-1825.45% (393) transporter, major facilitator family protein
M. smegmatis MC2 155MSMEG_0357-0.070.30% (505) transmembrane transport protein
M. ulcerans Agy99MUL_0051-1e-0523.40% (359) integral membrane protein
M. vanbaalenii PYR-1Mvan_1167-0.069.17% (506) protein of unknown function DUF894, DitE

CLUSTAL 2.0.9 multiple sequence alignment


Mb1288c|M.bovis_AF2122/97           -------------MRNS-NRGPAFLILFATLMAAAGDGVSIVAFP--WLV
Rv1258c|M.tuberculosis_H37Rv        -------------MRNS-NRGPAFLILFATLMAAAGDGVSIVAFP--WLV
MMAR_4182|M.marinum_M               -------------MRNS-SRGPAFLILFATLAACAGNGISIVAFP--WLV
MAV_1406|M.avium_104                ------------------------MILFATLLATAGTGISIVAFP--WLA
Mflv_5163|M.gilvum_PYR-GCK          MTSP----VSTSTWAPL-QSPVFRALWIAQFVSNLGTWMQTVGAQ--WML
Mvan_1167|M.vanbaalenii_PYR-1       MALA----GSTSTWAPL-GSPIFRALWIAQFVSNLGTWMQTVGAQ--WML
MSMEG_0357|M.smegmatis_MC2_155      MTTATPAMGATSTWAPL-ASPIYRALWIAQFVSNLGTWMQTVGAQ--WML
TH_1317|M.thermoresistible__bu      -------------------------LWIAQFVSNLGTWMQTVGAQ--WML
MAB_0880|M.abscessus_ATCC_1997      ------MADRGGIFVSL-RTRNYRLWISGQMVSLIGTWMQRVAQD--WLV
MUL_0051|M.ulcerans_Agy99           ----MHASAPVELWRSVRSLPDFWRLLQVRIASQFGDGLFQAGLAGALLF
                                                                  : :  *  :  ..     : 

Mb1288c|M.bovis_AF2122/97           LQREGS-AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSG
Rv1258c|M.tuberculosis_H37Rv        LQREGS-AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSG
MMAR_4182|M.marinum_M               LEREGS-AGQASIVAGAITLPLLFSTLVAGTAVDYFGRRPVSMVSDALSG
MAV_1406|M.avium_104                LQHRHS-ATDASIVAAAMTLPLVLATLIAGTAVDFFGRRRVSLVCDWLSG
Mflv_5163|M.gilvum_PYR-GCK          VDDPAA-AVLVPLVQTATTLPVMLLALPSGVLADLVDRRRLLIATQGAMA
Mvan_1167|M.vanbaalenii_PYR-1       VDDPRA-AVLVPLVQTATTLPVMLLALPSGVLADLIDRRRLLIATQGAMA
MSMEG_0357|M.smegmatis_MC2_155      VGDPRA-AVLVPLVQTATTLPVMLLALPSGVLADLVDRRRLLIAAQGATA
TH_1317|M.thermoresistible__bu      VSTPAA-EVLVPLVQTATTLPIMLLSLPSGVVADLVDRRRLLLATQSMMA
MAB_0880|M.abscessus_ATCC_1997      LDLSHGNAFLLGVVMALQFGPTLLLSVWGGMLADRYDKRRMLMLTQALMA
MUL_0051|M.ulcerans_Agy99           NPDRAADPMAIARAFAVLFLPYSLLGPFAGALMDRWDRRLVIVGANIGRL
                                         .       .      *  :    .*   *  .:* : :  :    

Mb1288c|M.bovis_AF2122/97           AAVAGVP-LVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAA
Rv1258c|M.tuberculosis_H37Rv        AAVAGVP-LVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAA
MMAR_4182|M.marinum_M               SAVAIVP-LIAWAFGDDAVSVAVLAALGACSATFDPAGITARQSMLPEAA
MAV_1406|M.avium_104                AAVTAVP-LTAWIFGAAAIDVAELAVLAFCAAAFDPAGMTARQSMLPEAA
Mflv_5163|M.gilvum_PYR-GCK          AGVGLLATLTGAGLTTPTVLLTLLFVIGCGQALTAPAWQAIQPDLVPSDQ
Mvan_1167|M.vanbaalenii_PYR-1       AGVGLLAVLTGAGLTTPTVLLMLLFVIGCGQALTAPAWQAIQPDLVPAHQ
MSMEG_0357|M.smegmatis_MC2_155      AGVASLATLTGAGLATPTVLLTLLFLIGCGQALTAPAWQAIQPDLVPREQ
TH_1317|M.thermoresistible__bu      AAVAILAALTAAQLTTPTVLLILLFLIGCGQAFTAPAWQAIQPELVPREQ
MAB_0880|M.abscessus_ATCC_1997      LFALTVGLLQVTGLVRIWHVMAVAFAMGCAAAIEAPTRQSFTIEMVGPEH
MUL_0051|M.ulcerans_Agy99           ILIAGIGTILAFEAGDLLLLFVALLANGLARFVAS-GLSASLPHVVPREQ
                                         :  :           .      .           :    ::    

Mb1288c|M.bovis_AF2122/97           ARAGWSLDRINGAYEAILNLAFIVGP----AIGGLMIATVGGITTMWITA
Rv1258c|M.tuberculosis_H37Rv        ARAGWSLDRINGAYEAILNLAFIVGP----AIGGLMIATVGGITTMWITA
MMAR_4182|M.marinum_M               ARAGWSLDRINSSYEAILNLAFVVGP----GIGGLMIATVGGITTMWITA
MAV_1406|M.avium_104                ARAGWSLDRTNSSYEAMLNLAFIVGP----GLGGLLIATLGGINTMWVTA
Mflv_5163|M.gilvum_PYR-GCK          IPAAAALGSMS------MNGARAIGP----AIAGALVSLTGPTIVFALNA
Mvan_1167|M.vanbaalenii_PYR-1       IPAAAALGSMS------MNGARAIGP----AIAGALVSLTGPTLVFALNA
MSMEG_0357|M.smegmatis_MC2_155      IPAAAALGSMS------MNGARAIGP----AIAGALVSLSGPTLVFALNA
TH_1317|M.thermoresistible__bu      IPAAAALTSMS------LNAARAVGP----AVAGVLVAISGPTLVFTLNA
MAB_0880|M.abscessus_ATCC_1997      LPNAVGLNSMV------FNLAGIIGP----ATSGVLIGLIGTGWVFLLNF
MUL_0051|M.ulcerans_Agy99           VVTMNSVATASGAVAAFVGANFMLLPRWLAGGGDHGAAAVIFTAMIPVAI
                                         .:          ..    : *    . ..   .       : :  

Mb1288c|M.bovis_AF2122/97           TAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTL
Rv1258c|M.tuberculosis_H37Rv        TAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTL
MMAR_4182|M.marinum_M               GAFGLSLLAIGALRLEGAGRPHHETRPDGLVSGVTQGLRFVWNLRVLRAL
MAV_1406|M.avium_104                GCFALSFLAIGALRLEGAGKPPRATRPVGLVTGIAEGVRFVWNLRVLRTL
Mflv_5163|M.gilvum_PYR-GCK          VSFVGIVLVLMWWRRPPVRSDYPPERA---LAALSAGGRYIRSSPIVRRI
Mvan_1167|M.vanbaalenii_PYR-1       VSFIGIVLVLISWRRPAVQRDFPPERA---LAALSAGGRYIRSSPIVRRI
MSMEG_0357|M.smegmatis_MC2_155      VSFVGIVAVLLLWRRPAAERMLPAERP---LAALSAGGRYIRSAPIVRRI
TH_1317|M.thermoresistible__bu      VSFAGIVVVLLLWKRSSAEQTLAAERP---LAALQAGHRYVRSSPVVRRI
MAB_0880|M.abscessus_ATCC_1997      VSFIAVGIALWRMRPGELHSSEPIPAAKG---QLRQGFSYVWRRRDLFMI
MUL_0051|M.ulcerans_Agy99           SLLLALRFAPRVLGPDDTKRAIHGSAVYAVITGWMHGVRTVVQIPTVAAA
                                      :     .                           *   :     :   

Mb1288c|M.bovis_AF2122/97           GMIDLTVTALYLPMESVLFPKYFTDH-QQPVQLG---WALMAIAGGGLVG
Rv1258c|M.tuberculosis_H37Rv        GMIDLTVTALYLPMESVLFPKYFTDH-QQPVQLG---WALMAIAGGGLVG
MMAR_4182|M.marinum_M               ALIDLTVTALYLPMESVLFPTYFSDR-QQPAQLG---SVLVALSLGSLVG
MAV_1406|M.avium_104                GLIDLAVTALYLPMESVLFPKYFADQ-HQPAQLG---WALMALALGGVAG
Mflv_5163|M.gilvum_PYR-GCK          LLRTVLFIAPGSAVWGLLPVIARDQLGLGSAGYG---ALLGALGVGAVLG
Mvan_1167|M.vanbaalenii_PYR-1       LLRTVLFIAPASALWGLLPVIAANQLGLGSAGYG---LLLGALGAGAVLG
MSMEG_0357|M.smegmatis_MC2_155      LLRTVLFIAPGSALWGLLAVIAKDQLDLTSSGYG---VLLGALGLGAVCG
TH_1317|M.thermoresistible__bu      LFRAALFILPASALWGLLPVVASSGLGLSSSGYG---LMLGALGAGAVLG
MAB_0880|M.abscessus_ATCC_1997      MLTVFLVSTFGLNFSLTLAVLARETFGRGAESYG---LLSTALAIGTLLG
MUL_0051|M.ulcerans_Agy99           LSGLAAHRMVVGVNSLLILLLVHHMRDVDVEGLGTALLFFAATGLGAFLA
                                                     :               *       * . * . .

Mb1288c|M.bovis_AF2122/97           ALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLV
Rv1258c|M.tuberculosis_H37Rv        ALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLV
MMAR_4182|M.marinum_M               ALGYGMLSNYVSRRTIMLTAVLTLGAATTGIALLPPLPVILVLCALIGVV
MAV_1406|M.avium_104                ALGYAVLSARLRRRTAVLTATLTFGATTAGIAVLPPLPVILGLCAVTGVV
Mflv_5163|M.gilvum_PYR-GCK          AFALSRLRARFGQNKLLIAGAAGFGMATAVLALVHNVALVAAALVVGGAA
Mvan_1167|M.vanbaalenii_PYR-1       AFVLSGLRTRFGQNVLLTAGAAGFAVATAVLALVPDFAAVLAALVVGGGA
MSMEG_0357|M.smegmatis_MC2_155      AFVLGRLQKMFELNTLLVVAAIGFGGATVVLALVHQVAVVVIALVLGGTA
TH_1317|M.thermoresistible__bu      ALTLSAWQSAFRQNTLLALAAVGFAAATAVAVLVPDVVVVLIGLTVGGMS
MAB_0880|M.abscessus_ATCC_1997      AT-FAARRTKKVRMTLFYGAAMAFGLSEVVVSVMPTYLSVALALVPAGLL
MUL_0051|M.ulcerans_Agy99           NVLTPGLIRRWGR-YATTNGALAAAAVTQLAGAGLLLPVMVVCGFLLGVA
                                                       ..   .              :       *  

Mb1288c|M.bovis_AF2122/97           YGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAA
Rv1258c|M.tuberculosis_H37Rv        YGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAA
MMAR_4182|M.marinum_M               YGPIQPIYNYVMQTRAPHYLRGRVVGVMTSLAYAAGPLGLLLAGPVADAA
MAV_1406|M.avium_104                YGPIQPIYNFVMQTRAPHHLRGRVVGVMAGLTYAAGPLGLLVAGPLADAA
Mflv_5163|M.gilvum_PYR-GCK          WLLTLSTLNASMQLSLPSWVRARGLSVYQLIFMGGQAVGSLLWGLLAGGT
Mvan_1167|M.vanbaalenii_PYR-1       WLLSLSTLNASMQLSLPAWVRARGLSVYQLIFMGGQAIGSLLWGLLAGAT
MSMEG_0357|M.smegmatis_MC2_155      WLLALSTLNASMQLSLPGWVRARGLSVYQLVFMGGQALGSLLWGLIAGAA
TH_1317|M.thermoresistible__bu      WLLALATLNASMQLSLPAWVRARGLSVYLLIFMGGQALGSTMWGLVAGST
MAB_0880|M.abscessus_ATCC_1997      ALTFTTSAMNIIQLSVDSQLRGRVMGIYMVAFLGGTPLGSPLVGWLADLH
MUL_0051|M.ulcerans_Agy99           GQVVKLCADSAMQIDVDGALRGHVFAVQDALFWVSYIVSVTVAAALIPDD
                                               :*      :*.: ..:       .  :.  : . :    

Mb1288c|M.bovis_AF2122/97           GLHATFLALALPIVCTGLVAIRLPALR---ELDLAPQADIDRPVGSAQ--
Rv1258c|M.tuberculosis_H37Rv        GLHATFLALALPIVCTGLVAIRLPALR---ELDLAPQADIDRPVGSAQ--
MMAR_4182|M.marinum_M               GLKVAFFALALPIAITGLMCIRLPSLR---ELDHAPTQDISETSLL----
MAV_1406|M.avium_104                GLKATFLTLAVPILAIGVVACGLPSLR---ELDRAPQFADDPGA------
Mflv_5163|M.gilvum_PYR-GCK          SSVISLLVSAGLLIFCGLSLWWWPLHAGTGNLDLTPSSHWPEPTLLFEPE
Mvan_1167|M.vanbaalenii_PYR-1       NSVTSLLVSAGLLVVCALSSLWWPLHAGTGNLDLTPSSHWPEPTLVFEPE
MSMEG_0357|M.smegmatis_MC2_155      GSVTALLVSAGLMGVCAVSAIWWPLHARTGNLDMTPSAHWPEPALIFEPE
TH_1317|M.thermoresistible__bu      STVVAMLISAGLLVVSGLSAWWWPLHPQTGQLDVSPSAHWPEPALVFEPE
MAB_0880|M.abscessus_ATCC_1997      GGRMPLLVGGLVSAAAGLVCATYLHRHP----CPVVAGEVPEADDMVPPA
MUL_0051|M.ulcerans_Agy99           GRAPVFVLVGSLIYLLGLCVHSIVGRR-------SSASNVEGC-------
                                    .    :.  .      .:                                

Mb1288c|M.bovis_AF2122/97           --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4182|M.marinum_M               --------------------------------------------------
MAV_1406|M.avium_104                --------------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK          PLDGPVLVITAYRVLPENEEPFMSAMARLGRSRQRTGASMWQLFRSIEQE
Mvan_1167|M.vanbaalenii_PYR-1       PLDGPVLVLTSYCVPAHNEGAFLAAMAVLGRSRQRTGASQWRLFRSVEQE
MSMEG_0357|M.smegmatis_MC2_155      PLDGPVVVLVSYRVEPAQETGFFEAMAALGRSRQRTGASQWQLFRSGEHA
TH_1317|M.thermoresistible__bu      PRDGPVLVLSTYRVAPEDEPAFLVAMQRQARSRQRTGAALWRLYRHLERE
MAB_0880|M.abscessus_ATCC_1997      PAATPVCEPTPLARRS----------------------------------
MUL_0051|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mb1288c|M.bovis_AF2122/97           --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4182|M.marinum_M               --------------------------------------------------
MAV_1406|M.avium_104                --------------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK          STFVETFIVRSWGEHMHQHYTRLTGQDQLIEQDVERYTEGEAVAEHYLAV
Mvan_1167|M.vanbaalenii_PYR-1       STFVETFIVRSWGEHMHQHYTRLTGQDQLIEQNVEQYTDGTPVSQHYLAV
MSMEG_0357|M.smegmatis_MC2_155      GTFVEAFIVRSWEEHLRQHHTRLTGHDLLVEETVRRFTVGEPTSQHLIAA
TH_1317|M.thermoresistible__bu      HTFVEAFLVRSWDEHLRQHHVRLTLVDQRVEEEVRRYAEGPPLVEHLIAV
MAB_0880|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_0051|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mb1288c|M.bovis_AF2122/97           ----------
Rv1258c|M.tuberculosis_H37Rv        ----------
MMAR_4182|M.marinum_M               ----------
MAV_1406|M.avium_104                ----------
Mflv_5163|M.gilvum_PYR-GCK          RDAR------
Mvan_1167|M.vanbaalenii_PYR-1       RDV-------
MSMEG_0357|M.smegmatis_MC2_155      KTH-------
TH_1317|M.thermoresistible__bu      NFDEITRRGV
MAB_0880|M.abscessus_ATCC_1997      ----------
MUL_0051|M.ulcerans_Agy99           ----------