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VADRGGIFVSLRTRNYRLWISGQMVSLIGTWMQRVAQDWLVLDLSHGNAFLLGVVMALQFGPTLLLSVWG GMLADRYDKRRMLMLTQALMALFALTVGLLQVTGLVRIWHVMAVAFAMGCAAAIEAPTRQSFTIEMVGPE HLPNAVGLNSMVFNLAGIIGPATSGVLIGLIGTGWVFLLNFVSFIAVGIALWRMRPGELHSSEPIPAAKG QLRQGFSYVWRRRDLFMIMLTVFLVSTFGLNFSLTLAVLARETFGRGAESYGLLSTALAIGTLLGATFAA RRTKKVRMTLFYGAAMAFGLSEVVVSVMPTYLSVALALVPAGLLALTFTTSAMNIIQLSVDSQLRGRVMG IYMVAFLGGTPLGSPLVGWLADLHGGRMPLLVGGLVSAAAGLVCATYLHRHPCPVVAGEVPEADDMVPPA PAATPVCEPTPLARRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0880 | - | - | 100% (436) | hypothetical protein MAB_0880 |
| M. abscessus ATCC 19977 | MAB_0940 | - | 2e-24 | 25.00% (392) | hypothetical protein MAB_0940 |
| M. abscessus ATCC 19977 | MAB_2780c | - | 3e-18 | 25.56% (403) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 4e-17 | 24.62% (390) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_5163 | - | 3e-48 | 33.89% (419) | protein of unknown function DUF894, DitE |
| M. tuberculosis H37Rv | Rv1258c | - | 4e-17 | 24.62% (390) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4182 | - | 2e-15 | 23.88% (381) | hypothetical protein MMAR_4182 |
| M. avium 104 | MAV_1406 | - | 1e-15 | 26.32% (399) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_6390 | - | 2e-61 | 36.13% (393) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_1317 | - | 7e-44 | 32.38% (420) | transmembrane transport protein |
| M. ulcerans Agy99 | MUL_0240 | - | 3e-08 | 21.70% (341) | hypothetical protein MUL_0240 |
| M. vanbaalenii PYR-1 | Mvan_1167 | - | 7e-47 | 33.89% (422) | protein of unknown function DUF894, DitE |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1288c|M.bovis_AF2122/97 ---------MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGS-
Rv1258c|M.tuberculosis_H37Rv ---------MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGS-
MMAR_4182|M.marinum_M ---------MRNSSRGPAFLILFATLAACAGNGISIVAFPWLVLEREGS-
MAV_1406|M.avium_104 -------------------MILFATLLATAGTGISIVAFPWLALQHRHS-
MAB_0880|M.abscessus_ATCC_1997 --MADRGGIFVSLRTRNYRLWISGQMVSLIGTWMQRVAQDWLVLDLSHGN
MSMEG_6390|M.smegmatis_MC2_155 -MRRYLAATFSALTIRDYRRYALGQTISVSGTWMQKLTQAWLVLELTDS-
Mflv_5163|M.gilvum_PYR-GCK MTSPVSTSTWAPLQSPVFRALWIAQFVSNLGTWMQTVGAQWMLVDDPAA-
Mvan_1167|M.vanbaalenii_PYR-1 MALAGSTSTWAPLGSPIFRALWIAQFVSNLGTWMQTVGAQWMLVDDPRA-
TH_1317|M.thermoresistible__bu --------------------LWIAQFVSNLGTWMQTVGAQWMLVSTPAA-
MUL_0240|M.ulcerans_Agy99 MGARVRGVVLVTGRVRELAVGLTAGFIVYLDTTVLLVAFGAISASFPEAS
. . : : : . .
Mb1288c|M.bovis_AF2122/97 AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVP
Rv1258c|M.tuberculosis_H37Rv AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVP
MMAR_4182|M.marinum_M AGQASIVAGAITLPLLFSTLVAGTAVDYFGRRPVSMVSDALSGSAVAIVP
MAV_1406|M.avium_104 ATDASIVAAAMTLPLVLATLIAGTAVDFFGRRRVSLVCDWLSGAAVTAVP
MAB_0880|M.abscessus_ATCC_1997 AFLLGVVMALQFGPTLLLSVWGGMLADRYDKRRMLMLTQALMALFALTVG
MSMEG_6390|M.smegmatis_MC2_155 PLLLGVTVAGQQLPTLLFTTLAGVLADRYSKRTILLWTALGGMLPALVLG
Mflv_5163|M.gilvum_PYR-GCK AVLVPLVQTATTLPVMLLALPSGVLADLVDRRRLLIATQGAMAAGVGLLA
Mvan_1167|M.vanbaalenii_PYR-1 AVLVPLVQTATTLPVMLLALPSGVLADLIDRRRLLIATQGAMAAGVGLLA
TH_1317|M.thermoresistible__bu EVLVPLVQTATTLPIMLLSLPSGVVADLVDRRRLLLATQSMMAAAVAILA
MUL_0240|M.ulcerans_Agy99 SSARSWVLDAYFIVFAALMVPGGRWADQFGSRNVFAIG-----VSTFILS
. .* .* . * : . :
Mb1288c|M.bovis_AF2122/97 LVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLD
Rv1258c|M.tuberculosis_H37Rv LVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLD
MMAR_4182|M.marinum_M LIAWAFGDDAVSVAVLAALGACSATFDPAGITARQSMLPEAAARAGWSLD
MAV_1406|M.avium_104 LTAWIFGAAAIDVAELAVLAFCAAAFDPAGMTARQSMLPEAAARAGWSLD
MAB_0880|M.abscessus_ATCC_1997 LLQVTGLVRIWHVMAVAFAMGCAAAIEAP---TRQSFTIEMVGPE--HLP
MSMEG_6390|M.smegmatis_MC2_155 VLVWIDVVNIWIVLAAAVAQGFADAVDKP---ARLTFVNDIATPE--TLA
Mflv_5163|M.gilvum_PYR-GCK TLTGAGLTTPTVLLTLLFVIGCGQALTAP---AWQAIQPDLVPSD--QIP
Mvan_1167|M.vanbaalenii_PYR-1 VLTGAGLTTPTVLLMLLFVIGCGQALTAP---AWQAIQPDLVPAH--QIP
TH_1317|M.thermoresistible__bu ALTAAQLTTPTVLLILLFLIGCGQAFTAP---AWQAIQPELVPRE--QIP
MUL_0240|M.ulcerans_Agy99 SVGCAVAPTLGALVAARAAQAVGAALMGP---ASLALILPYFGRG--SRA
: . :. . : ::
Mb1288c|M.bovis_AF2122/97 RINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAA
Rv1258c|M.tuberculosis_H37Rv RINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAA
MMAR_4182|M.marinum_M RINSSYEAILNLAFVVGPGIGGLMIATVGGITTMWITAGAFGLSLLAIGA
MAV_1406|M.avium_104 RTNSSYEAMLNLAFIVGPGLGGLLIATLGGINTMWVTAGCFALSFLAIGA
MAB_0880|M.abscessus_ATCC_1997 NAVGLNSMVFNLAGIIGPATSGVLIGLIGTGWVFLLNFVSFIAVGIALWR
MSMEG_6390|M.smegmatis_MC2_155 NAVTLNSIIQNSGKIAGPAVAGVLISAVGVSASFFLNAASYLPVVIALLL
Mflv_5163|M.gilvum_PYR-GCK AAAALGSMSMNGARAIGPAIAGALVSLTGPTIVFALNAVSFVGIVLVLMW
Mvan_1167|M.vanbaalenii_PYR-1 AAAALGSMSMNGARAIGPAIAGALVSLTGPTLVFALNAVSFIGIVLVLIS
TH_1317|M.thermoresistible__bu AAAALTSMSLNAARAVGPAVAGVLVAISGPTLVFTLNAVSFAGIVVVLLL
MUL_0240|M.ulcerans_Agy99 TAVSLWGTSAALAAALGPPLGGFLADTVGWRGIFLINVPIGLAVLAGLRN
. ** .* : * : :. :
Mb1288c|M.bovis_AF2122/97 LQLEGAGKPHHTSRPQGLVSGIA----------EGLRFVWNLRVLRTLGM
Rv1258c|M.tuberculosis_H37Rv LQLEGAGKPHHTSRPQGLVSGIA----------EGLRFVWNLRVLRTLGM
MMAR_4182|M.marinum_M LRLEGAGRPHHETRPDGLVSGVT----------QGLRFVWNLRVLRALAL
MAV_1406|M.avium_104 LRLEGAGKPPRATRPVGLVTGIA----------EGVRFVWNLRVLRTLGL
MAB_0880|M.abscessus_ATCC_1997 MRPGELHSSEPIPAAKGQLR-------------QGFSYVWRRRDLFMIML
MSMEG_6390|M.smegmatis_MC2_155 IRPHAPVITG-NVSAKGHLG-------------ETLRYVSARPHIAAALV
Mflv_5163|M.gilvum_PYR-GCK WRRPPVRSDYPPERALAALS-------------AGGRYIRSSPIVRRILL
Mvan_1167|M.vanbaalenii_PYR-1 WRRPAVQRDFPPERALAALS-------------AGGRYIRSSPIVRRILL
TH_1317|M.thermoresistible__bu WKRSSAEQTLAAERPLAALQ-------------AGHRYVRSSPVVRRILF
MUL_0240|M.ulcerans_Agy99 VDNRGDAVAGQLVNTSAIVLIASGVGALTAGILEGPSWGWGQRRTLLLLI
. . : : .
Mb1288c|M.bovis_AF2122/97 IDLTVTALYLP------------------------------------MES
Rv1258c|M.tuberculosis_H37Rv IDLTVTALYLP------------------------------------MES
MMAR_4182|M.marinum_M IDLTVTALYLP------------------------------------MES
MAV_1406|M.avium_104 IDLAVTALYLP------------------------------------MES
MAB_0880|M.abscessus_ATCC_1997 TVFLVSTFGLN------------------------------------FSL
MSMEG_6390|M.smegmatis_MC2_155 LMAVSGLLAFN------------------------------------WNV
Mflv_5163|M.gilvum_PYR-GCK RTVLFIAPGSA------------------------------------VWG
Mvan_1167|M.vanbaalenii_PYR-1 RTVLFIAPASA------------------------------------LWG
TH_1317|M.thermoresistible__bu RAALFILPASA------------------------------------LWG
MUL_0240|M.ulcerans_Agy99 AGAILLATAMVGVARHHRRAEPIHDFDKGRFFAANAATAIFGAGFYGLLL
Mb1288c|M.bovis_AF2122/97 VLFPKYFTDH-QQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMST
Rv1258c|M.tuberculosis_H37Rv VLFPKYFTDH-QQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMST
MMAR_4182|M.marinum_M VLFPTYFSDR-QQPAQLGSVLVALSLGSLVGALGYGMLSNYVSRRTIMLT
MAV_1406|M.avium_104 VLFPKYFADQ-HQPAQLGWALMALALGGVAGALGYAVLSARLRRRTAVLT
MAB_0880|M.abscessus_ATCC_1997 TLAVLARETFGRGAESYGLLSTALAIGTLLGAT-FAARRTKKVRMTLFYG
MSMEG_6390|M.smegmatis_MC2_155 LLPTLARDTFGGDARVVGFAFTSMGVGAVFGG--LALAGVLRGTSKWLIL
Mflv_5163|M.gilvum_PYR-GCK LLPVIARDQLGLGSAGYGALLGALGVGAVLGAFALSRLRARFGQNKLLIA
Mvan_1167|M.vanbaalenii_PYR-1 LLPVIAANQLGLGSAGYGLLLGALGAGAVLGAFVLSGLRTRFGQNVLLTA
TH_1317|M.thermoresistible__bu LLPVVASSGLGLSSSGYGLMLGALGAGAVLGALTLSAWQSAFRQNTLLAL
MUL_0240|M.ulcerans_Agy99 AVVFFLTSHWHYSTFEAGLAMMPIFVAAALAAIPAGRIADARGHRWAVIP
: . * .: . .. . .
Mb1288c|M.bovis_AF2122/97 AVLTLGLASMVIAFLPP-----LPVIMVLCAVVGLVYGPIQPIYNYVIQT
Rv1258c|M.tuberculosis_H37Rv AVLTLGLASMVIAFLPP-----LPVIMVLCAVVGLVYGPIQPIYNYVIQT
MMAR_4182|M.marinum_M AVLTLGAATTGIALLPP-----LPVILVLCALIGVVYGPIQPIYNYVMQT
MAV_1406|M.avium_104 ATLTFGATTAGIAVLPP-----LPVILGLCAVTGVVYGPIQPIYNFVMQT
MAB_0880|M.abscessus_ATCC_1997 AAMAFGLSEVVVSVMPT-----YLSVALALVPAGLLALTFTTSAMNIIQL
MSMEG_6390|M.smegmatis_MC2_155 NGCVLGAALALTGLMPT-----VTIAYALLFVVGAASVTFRSTATTLLQL
Mflv_5163|M.gilvum_PYR-GCK GAAGFGMATAVLALVHN-----VALVAAALVVGGAAWLLTLSTLNASMQL
Mvan_1167|M.vanbaalenii_PYR-1 GAAGFAVATAVLALVPD-----FAAVLAALVVGGGAWLLSLSTLNASMQL
TH_1317|M.thermoresistible__bu AAVGFAAATAVAVLVPD-----VVVVLIGLTVGGMSWLLALATLNASMQL
MUL_0240|M.ulcerans_Agy99 GCWVFALGVFLFWLLTTSRADYASRWLPGSILCGIGIRCVMPVLASAAID
:. .: * .
Mb1288c|M.bovis_AF2122/97 RAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIV
Rv1258c|M.tuberculosis_H37Rv RAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIV
MMAR_4182|M.marinum_M RAPHYLRGRVVGVMTSLAYAAGPLGLLLAGPVADAAGLKVAFFALALPIA
MAV_1406|M.avium_104 RAPHHLRGRVVGVMAGLTYAAGPLGLLVAGPLADAAGLKATFLTLAVPIL
MAB_0880|M.abscessus_ATCC_1997 SVDSQLRGRVMGIYMVAFLGGTPLGSPLVGWLADLHGGRMPLLVGGLVSA
MSMEG_6390|M.smegmatis_MC2_155 YSDPGVRGRIISLLVLATNGTTPVGGPMIGWICTHANPRVACLVGGLGTV
Mflv_5163|M.gilvum_PYR-GCK SLPSWVRARGLSVYQLIFMGGQAVGSLLWGLLAGGTSSVISLLVSAGLLI
Mvan_1167|M.vanbaalenii_PYR-1 SLPAWVRARGLSVYQLIFMGGQAIGSLLWGLLAGATNSVTSLLVSAGLLV
TH_1317|M.thermoresistible__bu SLPAWVRARGLSVYLLIFMGGQALGSTMWGLVAGSTSTVVAMLISAGLLV
MUL_0240|M.ulcerans_Agy99 AMPGQLLGTANALNSMLRQFGAALGTAAVGTLLVERSGHSPIDVGSFRVV
: . .: .:* * : . . .
Mb1288c|M.bovis_AF2122/97 CTGLVAIRLPALR----------------ELDLAPQADIDRPVGSAQ---
Rv1258c|M.tuberculosis_H37Rv CTGLVAIRLPALR----------------ELDLAPQADIDRPVGSAQ---
MMAR_4182|M.marinum_M ITGLMCIRLPSLR----------------ELDHAPTQDISETSLL-----
MAV_1406|M.avium_104 AIGVVACGLPSLR----------------ELDRAPQFADDPGA-------
MAB_0880|M.abscessus_ATCC_1997 AAGLVCATYLHRHPCPVVAGEVPEADDMVPPAPAATPVCEPTPLARRS--
MSMEG_6390|M.smegmatis_MC2_155 AAALAHWAYLR----------------------KAGTRKDPIPL------
Mflv_5163|M.gilvum_PYR-GCK FCGLSLWWWPLHAGTGNLDLTPSSHWPEPTLLFEPEPLDGPVLVITAYRV
Mvan_1167|M.vanbaalenii_PYR-1 VCALSSLWWPLHAGTGNLDLTPSSHWPEPTLVFEPEPLDGPVLVLTSYCV
TH_1317|M.thermoresistible__bu VSGLSAWWWPLHPQTGQLDVSPSAHWPEPALVFEPEPRDGPVLVLSTYRV
MUL_0240|M.ulcerans_Agy99 WAFLGTLTIATIPFALRLIRPGVATTGRGAPTGSRRMRIATLAVSRSTFR
:
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4182|M.marinum_M --------------------------------------------------
MAV_1406|M.avium_104 --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6390|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK LPENEEPFMSAMARLGRSRQRTGASMWQLFRSIEQESTFVETFIVRSWGE
Mvan_1167|M.vanbaalenii_PYR-1 PAHNEGAFLAAMAVLGRSRQRTGASQWRLFRSVEQESTFVETFIVRSWGE
TH_1317|M.thermoresistible__bu APEDEPAFLVAMQRQARSRQRTGAALWRLYRHLEREHTFVEAFLVRSWDE
MUL_0240|M.ulcerans_Agy99 KKHLRANDQ-----------------------------------------
Mb1288c|M.bovis_AF2122/97 ----------------------------------------------
Rv1258c|M.tuberculosis_H37Rv ----------------------------------------------
MMAR_4182|M.marinum_M ----------------------------------------------
MAV_1406|M.avium_104 ----------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 ----------------------------------------------
MSMEG_6390|M.smegmatis_MC2_155 ----------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK HMHQHYTRLTGQDQLIEQDVERYTEGEAVAEHYLAVRDAR------
Mvan_1167|M.vanbaalenii_PYR-1 HMHQHYTRLTGQDQLIEQNVEQYTDGTPVSQHYLAVRDV-------
TH_1317|M.thermoresistible__bu HLRQHHVRLTLVDQRVEEEVRRYAEGPPLVEHLIAVNFDEITRRGV
MUL_0240|M.ulcerans_Agy99 ----------------------------------------------