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MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVE QDAMAQIASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQ QLLSEASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIR HRSTRTRSHRGKRGELLPRAATSSLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02677 | - | - | 100% (236) | putative TetR-family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 3e-61 | 70.86% (175) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3103 | - | 2e-06 | 25.14% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 2e-61 | 71.43% (175) | transcriptional regulatory protein |
| M. abscessus ATCC 19977 | MAB_4352c | - | 1e-13 | 28.57% (168) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0224 | - | 1e-59 | 69.71% (175) | transcriptional regulatory protein |
| M. avium 104 | MAV_5253 | - | 4e-63 | 73.71% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3874 | - | 2e-05 | 27.34% (128) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 2e-17 | 32.37% (173) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 3e-59 | 69.14% (175) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 9e-07 | 34.83% (89) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0224|M.marinum_M --------MEIKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPE
MUL_4890|M.ulcerans_Agy99 --------MESKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPE
Mb0080|M.bovis_AF2122/97 --------MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPE
Rv0078|M.tuberculosis_H37Rv --------MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPE
MAV_5253|M.avium_104 --------MESKRRTQEER---SAATRDALIAAARKLWGLRGYTEVGTPE
MLBr_02677|M.leprae_Br4923 --------MESQRRTQEER---STATRDALTLARHRLWRLRGYAEVGTPE
TH_3094|M.thermoresistible__bu --------MSKRGGRVEDRRARGDQTRRDLIDAGRALFVDPGYFHTSVGD
Mflv_3103|M.gilvum_PYR-GCK -------MRSPTDRRQPQK---SDLRRVAILESLNHHLRESGFDALNIAA
MSMEG_3874|M.smegmatis_MC2_155 MVRPSTPVRSPTDRRQPQR---SDLRRTAILEALNEHLQKTGFDALNIAE
MAB_4352c|M.abscessus_ATCC_199 --------MVPLRQAQALA------TRQRLVDVATELFALHGFTSVTTTS
Mvan_4321|M.vanbaalenii_PYR-1 ---------MAERWTKERR---TEHTRQILLDAAEEVFARKGLTGAALEE
* : *
MMAR_0224|M.marinum_M IAAEAGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAAT
MUL_4890|M.ulcerans_Agy99 IAAEAGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAAT
Mb0080|M.bovis_AF2122/97 IATEAGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAAT
Rv0078|M.tuberculosis_H37Rv IATEAGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAAT
MAV_5253|M.avium_104 IAAAAGV-TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGAST
MLBr_02677|M.leprae_Br4923 IAKEADT-TRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKT
TH_3094|M.thermoresistible__bu LVERSGVGTRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SD
Mflv_3103|M.gilvum_PYR-GCK VAKRAGV-TRSAFYFYFENKAAAVAALLEPMYDDGFL--ASDILTDTTQP
MSMEG_3874|M.smegmatis_MC2_155 VARQAGV-GRSAFYFYFENKAAAVAALLEPMHEALLA--ANNILADLTRP
MAB_4352c|M.abscessus_ATCC_199 LSEASGM-TRGALYHHFANMTEVMEAVFERAEG--FLVAEVNHSLTSIES
Mvan_4321|M.vanbaalenii_PYR-1 IAEAAGF-TRGAIYSQFGAKEKLFLAVVDRQRQR-FLDGFADVMMSFHRL
: :. *.*.* * . :.:
MMAR_0224|M.marinum_M PADAIRAAVDAWLEVSG---DPEVRQLILLDAPAVLGWAGFRDVAQRYSL
MUL_4890|M.ulcerans_Agy99 PADAIRAAVDAWLEVSG---DPEVRQLILLDAPAVLGWAGFCDVAQRYSL
Mb0080|M.bovis_AF2122/97 PADAIRAAVDAWLEVSG---DPEVRQLVLLDAPVVLGWAGFRDVAQRYSL
Rv0078|M.tuberculosis_H37Rv PADAIRAAVDAWLEVSG---DPEVRQLILLDAPVVLGWAGFRDVAQRYSL
MAV_5253|M.avium_104 PTDAIRAAVDAWLEVSA---DPEVRQLILLDAPSVLGWAEFRDVAQRYSL
MLBr_02677|M.leprae_Br4923 PVDAIRAKVDAWLEGLA---DPQVRQLILLYAPSVLGWAAFRDVAQHYSL
TH_3094|M.thermoresistible__bu SWERLTRGLHGFLDAAA---EPEVQRIILIDGPVVLGWQTLRSIEERSSL
Mflv_3103|M.gilvum_PYR-GCK PARRVRAMLEALLDTVD---EHRYLLQAMLEARATSAAIRHVWDEARETF
MSMEG_3874|M.smegmatis_MC2_155 PGERIRATLDAVLRTAE---DHRYLFQAMLEARGTSGAVRDMWDAARESF
MAB_4352c|M.abscessus_ATCC_199 PAERFLAIGSAVLDVLAR--EPIVQRIVFVEAPMALGWSRWRALDGGRSL
Mvan_4321|M.vanbaalenii_PYR-1 SDVDIDELAERWRQLSSGPDRAALGHELTLYLLRNPEARESVAGQRRETV
. . : :.
MMAR_0224|M.marinum_M GMTEQ-LITEAIRAGQLDRHPVRPLAHVLIG-ALDEAAMFIATAD-----
MUL_4890|M.ulcerans_Agy99 GMTEQ-LITEAIRAGQLDRHPVRPLAHVLIG-ALDEAAMFIATAD-----
Mb0080|M.bovis_AF2122/97 GMTEQ-LITEAIRAGQLARQPVRPLAQVLIG-ALDEAAMFIATAD-----
Rv0078|M.tuberculosis_H37Rv GMTEQ-LITEAIRAGQLARQPVRPLAQVLIG-ALDEAAMFIATAD-----
MAV_5253|M.avium_104 GMTEQ-LLTEAIRAGELAEQPVRPLAHVLIG-ALDEAAMVIATAD-----
MLBr_02677|M.leprae_Br4923 GMTEQQLLSEASRARQLA----QPLDHVLIG-KLYESAMAIRRHHRLPEA
TH_3094|M.thermoresistible__bu AMIQQ-ILRRAIADGSIEEQPVTALTHMLVS-AVEEASLLIAHST-----
Mflv_3103|M.gilvum_PYR-GCK VPTVAQMIASERAAGRAPDGPGPEMIAGILL-EFNDRLMERHTLG----G
MSMEG_3874|M.smegmatis_MC2_155 VPTVSAVITAERESGRAPDGVDPKVLASLLM-EFNDRLLERLIIG----G
MAB_4352c|M.abscessus_ATCC_199 GLIQD-ILEELYRRGELVEAVDPQMAAQLILGAINESGMYAAAAP-----
Mvan_4321|M.vanbaalenii_PYR-1 RALGEFISKNVARIGGTLTIEAETLARVVLA--ANDGITLNSHLD-----
: : :: :
MMAR_0224|M.marinum_M DPKR-------------AR------------RESRQVLRRLIDGMLND--
MUL_4890|M.ulcerans_Agy99 DPKR-------------AR------------RESRQVLRRLIDGMLND--
Mb0080|M.bovis_AF2122/97 DPKR-------------AR------------RETRQVLRRLIDGMLNG--
Rv0078|M.tuberculosis_H37Rv DPKR-------------AR------------RETRQVLRRLIDGMLNG--
MAV_5253|M.avium_104 DPDR-------------AR------------RETRQVLQRLVDGMFDAR-
MLBr_02677|M.leprae_Br4923 SPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRA
TH_3094|M.thermoresistible__bu DPER--------AR-----------------SDAEAVLDTLLNALTRRRS
Mflv_3103|M.gilvum_PYR-GCK RLSR---------------------------DELLTAAQSVWLRTIYAND
MSMEG_3874|M.smegmatis_MC2_155 PLTR---------------------------RQLLEGAEAMWMGAIYASE
MAB_4352c|M.abscessus_ATCC_199 -SERS--------------------------SRAAEQLTLLCRGLLSPRS
Mvan_4321|M.vanbaalenii_PYR-1 -GE----------------------------DLYRPYLQLVISSVQTPP-
MMAR_0224|M.marinum_M ------
MUL_4890|M.ulcerans_Agy99 ------
Mb0080|M.bovis_AF2122/97 ------
Rv0078|M.tuberculosis_H37Rv ------
MAV_5253|M.avium_104 ------
MLBr_02677|M.leprae_Br4923 ATSSLL
TH_3094|M.thermoresistible__bu RSR---
Mflv_3103|M.gilvum_PYR-GCK GDELQ-
MSMEG_3874|M.smegmatis_MC2_155 PEQTR-
MAB_4352c|M.abscessus_ATCC_199 G-----
Mvan_4321|M.vanbaalenii_PYR-1 ------