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M. thermoresistible (build 8) TH_1791 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 3498477 - 3499103
length: 209

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1791--100% (209)transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_1661-1e-5758.38% (197) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0258-2e-0932.29% (96) transcriptional repressor, TetR family protein, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3605-2e-0737.33% (75) transcriptional regulatory protein TetR-family
M. gilvum PYR-GCKMflv_1253-1e-8476.65% (197) TetR family transcriptional regulator
M. tuberculosis H37RvRv3574-2e-0737.33% (75) transcriptional regulatory protein TetR-family
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1379c-2e-0927.50% (200) TetR family transcriptional regulator
M. marinum MMMAR_0249-3e-4447.40% (192) TetR family transcriptional regulator
M. avium 104MAV_2459-7e-5455.56% (198) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_6527-2e-8172.36% (199) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_4864-2e-4145.31% (192) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_4973-2e-5453.57% (196) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_1791|M.thermoresistible__bu      --------VLNE-RTSDRGSKGRQTRERLLGAAIAEFKRGGMAAADVASI
Mflv_1253|M.gilvum_PYR-GCK          --------MLKS-RTPERGRKGEQTRERLLGAAIAEFKRDGMAAADIGAI
MSMEG_6527|M.smegmatis_MC2_155      --------MLRQ-ERTGRWRKGMQTRERLLGAALAEFKRNGIAAADTAAI
MAV_2459|M.avium_104                --------MAD--RLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
Mvan_4973|M.vanbaalenii_PYR-1       -------MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGADIGAI
MMAR_0249|M.marinum_M               MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99           MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
Mb3605|M.bovis_AF2122/97            --------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAV
Rv3574|M.tuberculosis_H37Rv         --------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAV
MAB_1379c|M.abscessus_ATCC_199      ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
                                                 .         . * .::.*::*     *   .    :

TH_1791|M.thermoresistible__bu      VAAAGVAHGTFFFHFPTKEHVLVELERREEERMAAELNRYFRTPHTVRQT
Mflv_1253|M.gilvum_PYR-GCK          VSAAGVAHGTFFFHFPTKEHVLVELENREQERMAAELTRFYRRPHDVRAT
MSMEG_6527|M.smegmatis_MC2_155      VAAAGVAHGTFFFHFPTKEHVLIELEAREQERMVTELTRLYTRPHSVRDT
MAV_2459|M.avium_104                VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLKSEHDLASA
Mvan_4973|M.vanbaalenii_PYR-1       VSAAGVAHGTFFFHFPSKEHVLLELERREESRMATEFARYLDKKHDLASA
MMAR_0249|M.marinum_M               AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTDLVSV
MUL_4864|M.ulcerans_Agy99           AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTDLVSV
Mb3605|M.bovis_AF2122/97            ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQR
Rv3574|M.tuberculosis_H37Rv         ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQR
MAB_1379c|M.abscessus_ATCC_199      VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLAE
                                    .  ..:* **:: :* :* .:: .        :                 

TH_1791|M.thermoresistible__bu      LAEIVRLLEDLERRLGTRLFKDFLALHFSTTRPPSEEWSRHPVIAAVVEE
Mflv_1253|M.gilvum_PYR-GCK          LTKAVTVLEALERRLGSRLFKDFLALHFSTRRPPSEEWSAHPVIVAVVED
MSMEG_6527|M.smegmatis_MC2_155      LAETVRLLEKLERRLGRRLFKDFLALHFSTTRPPSQEWTRYPALTVIISE
MAV_2459|M.avium_104                LNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHPLIVLVANE
Mvan_4973|M.vanbaalenii_PYR-1       LAKVVELISALERRFGPLLFKELLALHFSPTRPSTDEWSDHPVIVSLVGA
MMAR_0249|M.marinum_M               LSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
MUL_4864|M.ulcerans_Agy99           LSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
Mb3605|M.bovis_AF2122/97            LNFMVGKLNRAMQRN-PLLTEAMTRAYVFADASAASEVDQVEKLIDSMFA
Rv3574|M.tuberculosis_H37Rv         LNFMVGKLNRAMQRN-PLLTEAMTRAYVFADASAASEVDQVEKLIDSMFA
MAB_1379c|M.abscessus_ATCC_199      YRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAA
                                        .  :            .      .       .              

TH_1791|M.thermoresistible__bu      LQRARDRGEIPE----------DVDVMHNGVSFLTGLYALLITMPESHDL
Mflv_1253|M.gilvum_PYR-GCK          LERARDRGEIPA----------DVDVMLRGVSFLVGLYALLITMPESREI
MSMEG_6527|M.smegmatis_MC2_155      LQRAQQRGEIPA----------DVDVMHVGVSFVVGLYALLITIPEARDA
MAV_2459|M.avium_104                IEGAQQRGETDP----------HVNPMNSAVFFLLGLYALLITTNH-WPT
Mvan_4973|M.vanbaalenii_PYR-1       IERARGDGEIHP----------EVDAFYSAAFFLLGIYGVLTTVAR-GDI
MMAR_0249|M.marinum_M               IARAQRANRVPP----------DADAGELGVIFLTGLFALLATGATTPDA
MUL_4864|M.ulcerans_Agy99           IAQAQRADRVAP----------DADAGELGVIFLTGLFALLATGATTPDA
Mb3605|M.bovis_AF2122/97            RAMANGEPTEDQ----------YHIARVISDVWLSNLLAWLTRRASATDV
Rv3574|M.tuberculosis_H37Rv         RAMANGEPTEDQ----------YHIARVISDVWLSNLLAWLTRRASATDV
MAB_1379c|M.abscessus_ATCC_199      IQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFEQ
                                       :                         .      : .           

TH_1791|M.thermoresistible__bu      RAPALSEYLTTYVHGMRVRSDPPAIAR
Mflv_1253|M.gilvum_PYR-GCK          RAPVIDEYVTTYMDALHAA--------
MSMEG_6527|M.smegmatis_MC2_155      RAPVLEVYLTTYLYGLRVLP-------
MAV_2459|M.avium_104                GHALLEDYVARTLRSLKP---------
Mvan_4973|M.vanbaalenii_PYR-1       RDAMLANLITTARRGLETR--------
MMAR_0249|M.marinum_M               RTALLNRFVTTVVHGMEAR--------
MUL_4864|M.ulcerans_Agy99           RTALLNGFVTTVVHGMEAR--------
Mb3605|M.bovis_AF2122/97            S-KRLDLAVRLLIGDQDSA--------
Rv3574|M.tuberculosis_H37Rv         S-KRLDLAVRLLIGDQDSA--------
MAB_1379c|M.abscessus_ATCC_199      LAHAVREILYYGLASDHHPQIAD----
                                        :   :