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DAALNLFSANGYDQTTTDEIAEAAGVSPRTFFRYFPTKESVLFFGEYDFIHAFSAVYLGRDESLSDYEAM SEAFAVLAPSLKRIRKRIAQYHEAVASSLVLLGRERRNHEANRETVAKVIAERRGLPAPDGECWLLASIG MLLVERALNQWLSTTDRGLDDIIRQEFAALPGVVK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1952 | - | - | 100% (176) | transcriptional regulator |
| M. avium 104 | MAV_2657 | - | 3e-77 | 78.98% (176) | transcriptional regulator |
| M. avium 104 | MAV_0474 | - | 2e-15 | 29.48% (173) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 6e-09 | 28.57% (175) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_0350 | - | 1e-13 | 38.06% (134) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 6e-09 | 28.57% (175) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02568 | - | 4e-05 | 42.86% (42) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 5e-09 | 24.72% (178) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_3861 | - | 2e-10 | 30.07% (153) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 5e-09 | 24.86% (177) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 1e-13 | 46.91% (81) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 3e-10 | 33.58% (134) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | 1e-14 | 29.89% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3860c|M.bovis_AF2122/97 ---------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIA
Rv3830c|M.tuberculosis_H37Rv ---------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIA
MUL_2933|M.ulcerans_Agy99 ---------MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELA
MAB_3837|M.abscessus_ATCC_1997 ---------MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIA
MSMEG_1420|M.smegmatis_MC2_155 ----------MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDDVA
TH_3524|M.thermoresistible__bu ------------------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIA
Mvan_1927|M.vanbaalenii_PYR-1 ----MSAAVIPGYDRRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIA
MAV_1952|M.avium_104 ----------------------------MDAALNLFSANGYDQTTTDEIA
MMAR_3861|M.marinum_M MASEGDGMNPANIGSLRDRRRAELFSLIQQTAHRLFAERGFDAVTTEDIA
Mflv_0350|M.gilvum_PYR-GCK -----MEGMNPEQPGLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIA
MLBr_02568|M.leprae_Br4923 -----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIA
* : .* .: :*
Mb3860c|M.bovis_AF2122/97 EDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQ
Rv3830c|M.tuberculosis_H37Rv EDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQ
MUL_2933|M.ulcerans_Agy99 REAGVTERTFFRHFPTKEAVLFQDYENQLEWLARALAQRPVSEPLFDAVL
MAB_3837|M.abscessus_ATCC_1997 AAAGIARRTVFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTALR
MSMEG_1420|M.smegmatis_MC2_155 AAAGISRRTLFRYYASKSAIPWGDFDSHLQHLQNLLRTLSSEVSLGDALR
TH_3524|M.thermoresistible__bu EAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAARSGS-LWKALA
Mvan_1927|M.vanbaalenii_PYR-1 QRAGLTERTFFRHFADKREVLFSGQAALIDLVTASVAAQEDTDPPLDVVA
MAV_1952|M.avium_104 EAAGVSPRTFFRYFPTKESVLFFGEYDFIHAFSAVYLGRDESLSDYEAMS
MMAR_3861|M.marinum_M AAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSYRSWPADESAVEALI
Mflv_0350|M.gilvum_PYR-GCK EAAFVSPRTFFRYFPTKESVLFS--DDLFNPIIEEFLAAPAELSPVAAYR
MLBr_02568|M.leprae_Br4923 AEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLL
* :: : : * : :
Mb3860c|M.bovis_AF2122/97 AAIF-SFP-YDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQL
Rv3830c|M.tuberculosis_H37Rv AAIF-SFP-YDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQL
MUL_2933|M.ulcerans_Agy99 ASVA-AFP-HDLEVVRQAATARSELISADRIANHLRVVQSSFAQVLTAFV
MAB_3837|M.abscessus_ATCC_1997 QAVL-TFNDFPVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFV
MSMEG_1420|M.smegmatis_MC2_155 EALL-TFNTYADHEMAEHRQRMRVILETEELQAYSMTMYAGWRTVIAEYV
TH_3524|M.thermoresistible__bu EASE-AVATAIAENPGIFLVRARMYGELPALRATMLRINDDWIDQMTTEV
Mvan_1927|M.vanbaalenii_PYR-1 AALT-AAGSALDGRGDRARQRQAVIDANPGLRERELIKLATLADTLAEAL
MAV_1952|M.avium_104 EAFA-VLAPSLKRIRKRIAQYHEAVASSLVLLGRERRNHEANRETVAKVI
MMAR_3861|M.marinum_M ALFV-SYARDAGD--LKLDTWRRAIATAPYLLSKSALVSEDDQHRFIEHV
Mflv_0350|M.gilvum_PYR-GCK HAAARVFETMAGSDYDYIIARQRLLYDLPEAKGALWNEHVGAIRRLTSAI
MLBr_02568|M.leprae_Br4923 RNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLM
. :
Mb3860c|M.bovis_AF2122/97 RRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVC
Rv3830c|M.tuberculosis_H37Rv RRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVC
MUL_2933|M.ulcerans_Agy99 RNRYADVA---NVDLVAEVAGATIAAALVVAVENWGRYG--CAEDLGELV
MAB_3837|M.abscessus_ATCC_1997 ARRSGTDP----GSLLPQTVAWTLLGVALAAYEQWLADE---SSKLTTLL
MSMEG_1420|M.smegmatis_MC2_155 ADRLGMST----TDLMPQTVAWLMLGVALSAYENWLADE---SVSLRGAI
TH_3524|M.thermoresistible__bu ARWLGSDA---AVDVRPRLAATVINGANRTAIDLWVSAD--GKGDLVELM
Mvan_1927|M.vanbaalenii_PYR-1 RQRGVEAP-------AARLAAEVGLAVFRVAFERWVQSP--GGAPLPTLI
MAV_1952|M.avium_104 AERRGLPAP----DGECWLLASIGMLLVERALNQWLSTT---DRGLDDII
MMAR_3861|M.marinum_M ASRMGVDAR---TDIRPALLVHTSLATVKFVFDRWLSTDPPSSPIFHVQM
Mflv_0350|M.gilvum_PYR-GCK AKRLGRPED----DYQARVTAGAIIGVFMAASDDEPMSG--------EAF
MLBr_02568|M.leprae_Br4923 RVGTRSSRP----DHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMI
Mb3860c|M.bovis_AF2122/97 HVALESLRVGISDTWTTLTVSS---------
Rv3830c|M.tuberculosis_H37Rv HVALESLRVGISDTWTTLTVSS---------
MUL_2933|M.ulcerans_Agy99 AASLDLVRSGLAPLS----------------
MAB_3837|M.abscessus_ATCC_1997 GKGFDAAEVGLRALR----------------
MSMEG_1420|M.smegmatis_MC2_155 AAAFEVARPGLDALQPAH-------------
TH_3524|M.thermoresistible__bu ADAVRLVRPTLDRIERESRTVANPVRRRDVV
Mvan_1927|M.vanbaalenii_PYR-1 AAAFADLRRIVA-------------------
MAV_1952|M.avium_104 RQEFAALPGVVK-------------------
MMAR_3861|M.marinum_M DQALRIALAGFR-------------------
Mflv_0350|M.gilvum_PYR-GCK LEALDLLDQALPR------------------
MLBr_02568|M.leprae_Br4923 NLFWHGLKGAPADRDFGPSIVAG--------