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PARQESRELSSKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSF LHDVVTPSGVSLQLPDSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQNQFRRFGMDII AASVRHAQDQGYGTELNPDHTAVAIALLFENFTSVLVGTSGSSGPGGLGVTITDEDAITTLSRIWKKTLY GF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1492 | - | - | 100% (213) | transcriptional regulatory protein |
| M. marinum M | MMAR_0533 | - | 5e-21 | 30.50% (200) | transcriptional regulatory protein |
| M. marinum M | MMAR_4840 | - | 3e-07 | 33.75% (80) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0279c | - | 7e-18 | 28.86% (201) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4467 | - | 3e-90 | 78.74% (207) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0273c | - | 7e-18 | 28.86% (201) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 7e-10 | 23.83% (214) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0314c | - | 4e-24 | 34.04% (188) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4026 | - | 2e-93 | 82.76% (203) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2071 | - | 4e-86 | 77.29% (207) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0641 | - | 2e-86 | 77.34% (203) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_2448 | - | 1e-118 | 99.53% (213) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1893 | - | 2e-88 | 78.74% (207) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0279c|M.bovis_AF2122/97 -----------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATT
Rv0273c|M.tuberculosis_H37Rv -----------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATT
MAB_0314c|M.abscessus_ATCC_199 ---------------------------------MDAARVVISRVGYAETR
MMAR_1492|M.marinum_M ------------MPARQESRELSSKGRQTRQAIEQAARKLFAERGFHGTT
MUL_2448|M.ulcerans_Agy99 ------------MPARQESRELSSKGRQTRQAIEQVARKLFAERGFHGTT
Mflv_4467|M.gilvum_PYR-GCK ------------MPPGS-SDALSAKGRQTRDALAQAARKLFAERGFHGTT
Mvan_1893|M.vanbaalenii_PYR-1 ------------MPPGP-AESLSAKGRQTRDAIEQAARKLFAERGFHGTT
MAV_4026|M.avium_104 ------------MP----AELLTAKGRQTRQAIEQAARKLFAERGFHGTT
MSMEG_2071|M.smegmatis_MC2_155 ------------MA----SGELGSKGRQTRTAIELAARKLFAERGFHGTT
TH_0641|M.thermoresistible__bu ------------MA----AETLSSKGRQTRLALEQAARKLFAERGFHGTT
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
.*. :. .
Mb0279c|M.bovis_AF2122/97 VADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS
Rv0273c|M.tuberculosis_H37Rv VADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS
MAB_0314c|M.abscessus_ATCC_199 VIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVATSDRP
MMAR_1492|M.marinum_M LADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTPSGVSLQLPDS
MUL_2448|M.ulcerans_Agy99 LADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTPSGVSLQLPDS
Mflv_4467|M.gilvum_PYR-GCK LSDITSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVAPSGLSVPLPES
Mvan_1893|M.vanbaalenii_PYR-1 LGDITSAAGKSPAVFYRYFADKEDLLAALAESFLHDVVAPSGLSVPLPES
MAV_4026|M.avium_104 LADITSAAGKSPAVFYRYFADKEDLLAALAESFLHEVVTPSGLSVHLPDS
MSMEG_2071|M.smegmatis_MC2_155 LADITSAAGKSPAVFYRYFTDKEDLLAALAESFLHDVVEPSGLNLHLPDS
TH_0641|M.thermoresistible__bu LADITSAAGKSPAVFYRYFVDKEDLLAALAESFLREVLAPGWLSVRLPDS
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRS-AVEALAEQLP
: ::: ** * ** *: .* :: : . . .
Mb0279c|M.bovis_AF2122/97 DRER--AYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPI
Rv0273c|M.tuberculosis_H37Rv DRER--AYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPI
MAB_0314c|M.abscessus_ATCC_199 PHEV--IRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPAR
MMAR_1492|M.marinum_M PDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQNQFRRFGM
MUL_2448|M.ulcerans_Agy99 PDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQNQFRRFGM
Mflv_4467|M.gilvum_PYR-GCK PDDDAFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQNEFRRFGM
Mvan_1893|M.vanbaalenii_PYR-1 PDDDAFFTMVVTGYWTMFKQNIGIMIAVAQLAATQSRFALVQNEFRRFGM
MAV_4026|M.avium_104 PDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQNEFRRFGI
MSMEG_2071|M.smegmatis_MC2_155 PDDAEFFTSVVTGYWNMFKQNIGIMIAVAQLAATQQRFAEVQNSFRRFGI
TH_0641|M.thermoresistible__bu PDDDEFFTTVVGGYWNMFKQNIGIMIAVDQLAATQQRFADVQNEFRRFGM
MLBr_01070|M.leprae_Br4923 ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWI
.: . . .. . .
Mb0279c|M.bovis_AF2122/97 SFITETVKRAQAHGYCVGDDP-QLMAEAIVAMFNQFCYLQLS-GKRSR--
Rv0273c|M.tuberculosis_H37Rv SFITETVKRAQAHGYCVGDDP-QLMAEAIVAMFNQFCYLQLS-GKRSR--
MAB_0314c|M.abscessus_ATCC_199 TMIANNIRHLQARGYCPGMDP-DITASAIGAMLDYFCYVWLVEGGERG--
MMAR_1492|M.marinum_M DIIAASVRHAQDQGYGTELNP-DHTAVAIALLFENFTSVLVGTSGSSGPG
MUL_2448|M.ulcerans_Agy99 DIIAASVRHAQDQGYGTELNP-DHTAVAIALLFENFTSVLVGTSGSSGPG
Mflv_4467|M.gilvum_PYR-GCK DIVAASVRRAQEQGYGTELNP-EHTAAAIALLFENFTTVFVGASG-----
Mvan_1893|M.vanbaalenii_PYR-1 DIVAASVRRAQEQGYGRELNA-EHTAAAIALLFENFTTVFVGASG-----
MAV_4026|M.avium_104 DLVAASVRRAQEQGYGTELHP-QHTAAAIALLFENFTTVFVGPSG-----
MSMEG_2071|M.smegmatis_MC2_155 DIVVASVRRAQEQGHAVGLVP-EHIGAAIALLFENFTTVFVGSSG-----
TH_0641|M.thermoresistible__bu DIVAASVRHAQQQGYGTDLDP-QHIAAAIALMFENFTAVFVGRGG-----
MLBr_01070|M.leprae_Br4923 DYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK-----
. :: : * . : . *: : : . .
Mb0279c|M.bovis_AF2122/97 --RGQPDDQACIQTLANIYYRAIYSKEDSSN---
Rv0273c|M.tuberculosis_H37Rv --RGQPDDQACIQTLANIYYRAIYSKEDSSN---
MAB_0314c|M.abscessus_ATCC_199 --RSAVTDEEAIDTLARIWFNALWWKSEGAHGAT
MMAR_1492|M.marinum_M GLGVTITDEDAITTLSRIWKKTLYGF--------
MUL_2448|M.ulcerans_Agy99 GLGVTITDEDAITTLSRIWKKTLYGF--------
Mflv_4467|M.gilvum_PYR-GCK -LGVQMTDQDAIATLSRIWKKTLYGY--------
Mvan_1893|M.vanbaalenii_PYR-1 -LDVDIDDEAAIATLSRIWKKTLYGY--------
MAV_4026|M.avium_104 -LGIEISDEDAIATLSTIWKKTLYGV--------
MSMEG_2071|M.smegmatis_MC2_155 -LGVELDDREAITTLATIWKKTLYGF--------
TH_0641|M.thermoresistible__bu -PGLQISDADAVRTLATIWKKTLYGC--------
MLBr_01070|M.leprae_Br4923 ---PLIPDKKVIDTLVHIWLASIYGS--------
* : ** *: :::