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M. tuberculosis H37Rv Rv0402c (mmpL1)

annotation: PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL1
coordinates: 480355 - 483231
length: 958

RSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDF
QQFDSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLN
LTGDQGGSQANESVAAVQRIVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIA
YRSLSAALIMLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATG
QNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLASLTLAPAIIAVAS
RFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLA
SDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARVQSITRPLGAPIDHSSIPFQLGM
QSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIAD
FDDFWRPLRSFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQRQLLAQLDPTIA
TMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFDAANNDDSFYLPPEAFQNPDFQRGLKLFLSPDG
TCARFVITHRGDPASAEGISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVVAS
LCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPLHWLVLPMAIIVMLAVGSDYNLL
LIARFQEEIGAGLKTGMIRAMAGTGRVVTIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRS
YMTPALATLLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0402cmmpL1-100% (958)PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL1
M. tuberculosis H37RvRv0450cmmpL40.057.57% (945) transmembrane transport protein MmpL4
M. tuberculosis H37RvRv2339mmpL90.056.32% (925) transmembrane transport protein MmpL9

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1583mmpL60.059.18% (931) transmembrane transport protein MmpL6
M. gilvum PYR-GCKMflv_4418-0.056.75% (941) transport protein
M. leprae Br4923MLBr_02378-0.056.16% (917) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_3150-0.055.12% (918) MmpL family protein
M. marinum MMMAR_0704mmpL10.077.50% (951) transmembrane transport protein MmpL1
M. avium 104MAV_4696-0.055.41% (933) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.057.02% (919) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.052.67% (936) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_3688mmpL4_10.055.93% (928) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_1936-0.056.38% (940) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02378|M.leprae_Br4923          -MTVKCAN--------------------DLDTHTKPPFVARMIHRFAVPI
MAB_3150|M.abscessus_ATCC_1997      -MRHGSG-----------------------DHTARPPRIARLIRTLSIPI
Mb1583|M.bovis_AF2122/97            -MSN--------------------HHRPR-------PWLPHTIRRLSLPI
MAV_4696|M.avium_104                -MSEPV------------------EAAPRVDQPLIPPFLPRMIHRLALPI
Mflv_4418|M.gilvum_PYR-GCK          -MADAG-----------------------------RSGIGRIIRVLAVPI
Mvan_1936|M.vanbaalenii_PYR-1       -MADAG-----------------------------RSGIGRIIHLLAVPI
MSMEG_3496|M.smegmatis_MC2_155      -MSNP----SHDAPTD--------AMGVSGPKHARPGGIAKWIRVLAVPI
TH_3260|M.thermoresistible__bu      MTANPGHVRTDEAPTD--------RLDIKVSTHG-PSFISTWIRRLSLPI
MUL_3688|M.ulcerans_Agy99           -MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPI
Rv0402c|M.tuberculosis_H37Rv        -MRSQR-------------------------LAGHLSAAARTIHALSLPI
MMAR_0704|M.marinum_M               -MSSLN-------------------------STGYVLGAARWVRRLSLPI
                                                                              :: :::**

MLBr_02378|M.leprae_Br4923          ILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEG
MAB_3150|M.abscessus_ATCC_1997      ILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVFGEF
Mb1583|M.bovis_AF2122/97            LLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVFHEF
MAV_4696|M.avium_104                VLVWLGIVFITNTVAPQLEVVAKTHSVSMSPTDAASFQSMMKVGATFKEF
Mflv_4418|M.gilvum_PYR-GCK          VLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEF
Mvan_1936|M.vanbaalenii_PYR-1       VLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEF
MSMEG_3496|M.smegmatis_MC2_155      ILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEF
TH_3260|M.thermoresistible__bu      IVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEG
MUL_3688|M.ulcerans_Agy99           ILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFREF
Rv0402c|M.tuberculosis_H37Rv        ILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQF
MMAR_0704|M.marinum_M               VLFWVGLAVLVNVIAPQLQAVVKARSVALGPHDAPSLLAMKRIGKNFQQF
                                    :: *: :    .   *.*: * . : .   . : .*  :* : *  * : 

MLBr_02378|M.leprae_Br4923          NSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLT
MAB_3150|M.abscessus_ATCC_1997      DSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPLT
Mb1583|M.bovis_AF2122/97            DSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGDPLT
MAV_4696|M.avium_104                NSDNSAMILLEGDKPLGAEAHRYYDEIVRRVEQDKKHVQHVQDFWSDPLT
Mflv_4418|M.gilvum_PYR-GCK          DSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLT
Mvan_1936|M.vanbaalenii_PYR-1       DSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPLT
MSMEG_3496|M.smegmatis_MC2_155      KSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLT
TH_3260|M.thermoresistible__bu      SSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLT
MUL_3688|M.ulcerans_Agy99           DSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRLT
Rv0402c|M.tuberculosis_H37Rv        DSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLT
MMAR_0704|M.marinum_M               ESDTIAMVVLEGQHELGEDAHRYYDRLVGKLAQDKIHVEHIDNFWGDTLT
                                    .*:.  *::***:. *.  *: :** :: .:  *  ::: : : *.* **

MLBr_02378|M.leprae_Br4923          APGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGI
MAB_3150|M.abscessus_ATCC_1997      ASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAETP---GPAGV
Mb1583|M.bovis_AF2122/97            AAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP---PPAGV
MAV_4696|M.avium_104                AAGSQSHDQKAAYVQVYLAGNMGGGLANESALAVRKIVDSVP---APPGI
Mflv_4418|M.gilvum_PYR-GCK          ASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---APPGI
Mvan_1936|M.vanbaalenii_PYR-1       ASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---APPGL
MSMEG_3496|M.smegmatis_MC2_155      ASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---APPGV
TH_3260|M.thermoresistible__bu      ATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGV
MUL_3688|M.ulcerans_Agy99           AAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---EPAGV
Rv0402c|M.tuberculosis_H37Rv        AAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVP---PPPGI
MMAR_0704|M.marinum_M               AASSQSADGKAAYVQLYLAGDQGGSQANESVTAVQRIIGDMP---PPPGI
                                    *.. ** *  ::** :   *: *   : *:  :*: ::        * *:

MLBr_02378|M.leprae_Br4923          TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
MAB_3150|M.abscessus_ATCC_1997      QAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITTIVA
Mb1583|M.bovis_AF2122/97            KAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTMVLV
MAV_4696|M.avium_104                KAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSIITVAVM
Mflv_4418|M.gilvum_PYR-GCK          KAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLI
Mvan_1936|M.vanbaalenii_PYR-1       KAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLI
MSMEG_3496|M.smegmatis_MC2_155      KAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILT
TH_3260|M.thermoresistible__bu      QAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIA
MUL_3688|M.ulcerans_Agy99           KAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVIQ
Rv0402c|M.tuberculosis_H37Rv        KAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIM
MMAR_0704|M.marinum_M               KAYLTGPGPLGADRVIYGDRSLQVITGISIAVIALMLAITYRSLWTVLFT
                                     *::**  .   *    .. .       :. .:   * ..:**. :  . 

MLBr_02378|M.leprae_Br4923          LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
MAB_3150|M.abscessus_ATCC_1997      LLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFLL
Mb1583|M.bovis_AF2122/97            LITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFVL
MAV_4696|M.avium_104                LGMVFIELAAARGVVATLGNYGVMGLSTFANNMLVLMAIAAGTDYAIFVV
Mflv_4418|M.gilvum_PYR-GCK          LFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
Mvan_1936|M.vanbaalenii_PYR-1       LFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
MSMEG_3496|M.smegmatis_MC2_155      LVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLI
TH_3260|M.thermoresistible__bu      LFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLI
MUL_3688|M.ulcerans_Agy99           LFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFLV
Rv0402c|M.tuberculosis_H37Rv        LLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLV
MMAR_0704|M.marinum_M               LLTVGIELITVRGVIAVLATNGLMDLSTFTVNVLVALAIAASTDYIIFLV
                                    *  .       :*::: :.   ::.*:.:: .::. : ** ..** **  

MLBr_02378|M.leprae_Br4923          GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
MAB_3150|M.abscessus_ATCC_1997      GRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPLF
Mb1583|M.bovis_AF2122/97            GRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPYF
MAV_4696|M.avium_104                GRYHEARGLGETREQAFYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYF
Mflv_4418|M.gilvum_PYR-GCK          GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
Mvan_1936|M.vanbaalenii_PYR-1       GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
MSMEG_3496|M.smegmatis_MC2_155      GRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYF
TH_3260|M.thermoresistible__bu      GRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYF
MUL_3688|M.ulcerans_Agy99           GRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPWF
Rv0402c|M.tuberculosis_H37Rv        GRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYF
MMAR_0704|M.marinum_M               GRYQESVTAGQDRELAYYTMFRGTGHVVLASGLTVAGAMYCLSFTRLPYF
                                    ***:*:      :  :::* : ..  *:*.**:*: **  ** : *:* *

MLBr_02378|M.leprae_Br4923          QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKV-RGWRR
MAB_3150|M.abscessus_ATCC_1997      RSMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPKRKYDE-GGWRR
Mb1583|M.bovis_AF2122/97            QSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRT-RGWRR
MAV_4696|M.avium_104                QSLGVPCAVGMLVAVLAALTLAPAMLTVASFFK-LMDPKRTLQT-RGWRR
Mflv_4418|M.gilvum_PYR-GCK          QTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISS-RGWRR
Mvan_1936|M.vanbaalenii_PYR-1       QTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISS-RGWRR
MSMEG_3496|M.smegmatis_MC2_155      QSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRT-RGWRK
TH_3260|M.thermoresistible__bu      QSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARV-RFWRK
MUL_3688|M.ulcerans_Agy99           NTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESKRAANRGRLWRR
Rv0402c|M.tuberculosis_H37Rv        NTLASPCAIGLVTVMLASLTLAPAIIAVASRFG-LFDPKRATTK-RRWRR
MMAR_0704|M.marinum_M               QTLALPCSIGLFVVVLASLTFAPAVIVLTSRFG-AFDPKRATTT-RRWRR
                                    .::. * ::     : ..*::..::: : : *   ::.**       **:

MLBr_02378|M.leprae_Br4923          IGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGF
MAB_3150|M.abscessus_ATCC_1997      IGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVGY
Mb1583|M.bovis_AF2122/97            IGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGY
MAV_4696|M.avium_104                MGTAVVRWPAPVLAVTIAVALVGLLALPGYKTDYDNRHFLPADTPANVGY
Mflv_4418|M.gilvum_PYR-GCK          IGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGY
Mvan_1936|M.vanbaalenii_PYR-1       IGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGY
MSMEG_3496|M.smegmatis_MC2_155      LGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGY
TH_3260|M.thermoresistible__bu      VGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGY
MUL_3688|M.ulcerans_Agy99           VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
Rv0402c|M.tuberculosis_H37Rv        IGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGY
MMAR_0704|M.marinum_M               IGTIVVRWPGPVLVATLLISLIGLLALPKYETNYDERHYIPAEAPSNIGY
                                    :*. :**** *::  :  : ::*:::** : ..*. * ::*   *:: * 

MLBr_02378|M.leprae_Br4923          AAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
MAB_3150|M.abscessus_ATCC_1997      AAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRV
Mb1583|M.bovis_AF2122/97            MAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLV
MAV_4696|M.avium_104                AAADRHFDQARLNPELLMIETDHDLRNPADFIVLDKVAKAVFHIPGIGRV
Mflv_4418|M.gilvum_PYR-GCK          AVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARV
Mvan_1936|M.vanbaalenii_PYR-1       AVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV
MSMEG_3496|M.smegmatis_MC2_155      AAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRV
TH_3260|M.thermoresistible__bu      EAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRV
MUL_3688|M.ulcerans_Agy99           AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
Rv0402c|M.tuberculosis_H37Rv        LASDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARV
MMAR_0704|M.marinum_M               RASDRHFPPARMEPELLMVEADHDLRNPTDMLILDRIARGIFHTPGIARV
                                     .:::**  **::*::*::*::**:*:.:*:::::::*:  ::  *:. :

MLBr_02378|M.leprae_Br4923          QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
MAB_3150|M.abscessus_ATCC_1997      QAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQMGI
Mb1583|M.bovis_AF2122/97            QAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEELGK
MAV_4696|M.avium_104                QTITRPLGTPLDHSTLGFQMGAQAAGRLQTQHYQEEQANNLLKQADELRK
Mflv_4418|M.gilvum_PYR-GCK          QTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQT
Mvan_1936|M.vanbaalenii_PYR-1       QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT
MSMEG_3496|M.smegmatis_MC2_155      QAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQK
TH_3260|M.thermoresistible__bu      QGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQL
MUL_3688|M.ulcerans_Agy99           QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
Rv0402c|M.tuberculosis_H37Rv        QSITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQR
MMAR_0704|M.marinum_M               QGITRPLGSPIEHSSIPFQLNMQSAVTLENLSDLKERVTDLSTLTDQIQR
                                    * :*** * .:.*::: *  .        .    .::  ::   :: :  

MLBr_02378|M.leprae_Br4923          TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
MAB_3150|M.abscessus_ATCC_1997      LIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFRPI
Mb1583|M.bovis_AF2122/97            TIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFRPI
MAV_4696|M.avium_104                TMATLHEQMQVTQDLSNTTHETTRLTKETVQITERLRDDIANFDDFLRPI
Mflv_4418|M.gilvum_PYR-GCK          NVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPV
Mvan_1936|M.vanbaalenii_PYR-1       NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV
MSMEG_3496|M.smegmatis_MC2_155      SVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPI
TH_3260|M.thermoresistible__bu      MIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPI
MUL_3688|M.ulcerans_Agy99           LIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
Rv0402c|M.tuberculosis_H37Rv        MIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPL
MMAR_0704|M.marinum_M               MIDITQRQEYLTRQLTEANHDVTAHTRRMEQNTNEFRDQLADFDDTWRPI
                                     :    .   :   :                    .** :  :**  **:

MLBr_02378|M.leprae_Br4923          RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
MAB_3150|M.abscessus_ATCC_1997      RNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLM
Mb1583|M.bovis_AF2122/97            RSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQ
MAV_4696|M.avium_104                RSYFYWEKHCYDIPVCWALRSVFNALDGIDQVAENIVNLSANLDKLDRIQ
Mflv_4418|M.gilvum_PYR-GCK          RNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELM
Mvan_1936|M.vanbaalenii_PYR-1       RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM
MSMEG_3496|M.smegmatis_MC2_155      RNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELM
TH_3260|M.thermoresistible__bu      RNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLM
MUL_3688|M.ulcerans_Agy99           RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLT
Rv0402c|M.tuberculosis_H37Rv        RSFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQ
MMAR_0704|M.marinum_M               RNYLHWERHCFDIPICASLRSLFDAIDGVDKLSEDVGGMARATDRIDMIQ
                                    *.: :** ** .:* * : *::::::*.:: : : .  :    ..     

MLBr_02378|M.leprae_Br4923          PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
MAB_3150|M.abscessus_ATCC_1997      PRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFD
Mb1583|M.bovis_AF2122/97            PQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFD
MAV_4696|M.avium_104                PKLVALIPPQIESQQRNLDTIMSNYAITQGLNDQAKAQADNATAQGDAFD
Mflv_4418|M.gilvum_PYR-GCK          PQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFD
Mvan_1936|M.vanbaalenii_PYR-1       PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD
MSMEG_3496|M.smegmatis_MC2_155      PQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFD
TH_3260|M.thermoresistible__bu      PQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFD
MUL_3688|M.ulcerans_Agy99           SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
Rv0402c|M.tuberculosis_H37Rv        RQLLAQLDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFD
MMAR_0704|M.marinum_M               PQLLAQLPQLIATMQTVKTLAQTLASTFSALVTQMEDMTRNSTQMGQALD
                                     :::  :   :   .              .   *           *  :*

MLBr_02378|M.leprae_Br4923          TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
MAB_3150|M.abscessus_ATCC_1997      EAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASVQG
Mb1583|M.bovis_AF2122/97            AAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEG
MAV_4696|M.avium_104                KAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVRLIISHEGDPASPEG
Mflv_4418|M.gilvum_PYR-GCK          DSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEG
Mvan_1936|M.vanbaalenii_PYR-1       DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG
MSMEG_3496|M.smegmatis_MC2_155      ASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEG
TH_3260|M.thermoresistible__bu      QARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEG
MUL_3688|M.ulcerans_Agy99           ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
Rv0402c|M.tuberculosis_H37Rv        AANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGDPASAEG
MMAR_0704|M.marinum_M               GSKNDDSFYLPPEAFQNPDFQRGLTLFLSPDGASARFVITHMGDPATAEG
                                     : *** ******.*.. **  .:  *:*.** ..*: : * *:* :  *

MLBr_02378|M.leprae_Br4923          IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
MAB_3150|M.abscessus_ATCC_1997      IETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAGI
Mb1583|M.bovis_AF2122/97            ISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGI
MAV_4696|M.avium_104                IRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLLIAGI
Mflv_4418|M.gilvum_PYR-GCK          ISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGI
Mvan_1936|M.vanbaalenii_PYR-1       ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI
MSMEG_3496|M.smegmatis_MC2_155      IKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGI
TH_3260|M.thermoresistible__bu      LAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAI
MUL_3688|M.ulcerans_Agy99           ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
Rv0402c|M.tuberculosis_H37Rv        ISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVV
MMAR_0704|M.marinum_M               ISHIDKIMLAADEAVKGTPLQAAHIYLAGTAATFKDIHEGTTYDLMIVVV
                                    :  :     *. :.:* :.   : :*:.**::. :*: :*   *:::. :

MLBr_02378|M.leprae_Br4923          SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
MAB_3150|M.abscessus_ATCC_1997      ASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDL
Mb1583|M.bovis_AF2122/97            AALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQL
MAV_4696|M.avium_104                AAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYLLGLKL
Mflv_4418|M.gilvum_PYR-GCK          AAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
Mvan_1936|M.vanbaalenii_PYR-1       AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
MSMEG_3496|M.smegmatis_MC2_155      AALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLEL
TH_3260|M.thermoresistible__bu      AAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEM
MUL_3688|M.ulcerans_Agy99           SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
Rv0402c|M.tuberculosis_H37Rv        ASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPL
MMAR_0704|M.marinum_M               AALCLIFIIMLGITRSPVASAVIVGTVALSLGSAFGLSVLIWQHILHMPL
                                    ::  **::**: :* : **: *****.  *:.::.*:***:** :. : :

MLBr_02378|M.leprae_Br4923          HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
MAB_3150|M.abscessus_ATCC_1997      HWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGKVV
Mb1583|M.bovis_AF2122/97            YWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVV
MAV_4696|M.avium_104                HWMVLAMAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVV
Mflv_4418|M.gilvum_PYR-GCK          HWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVV
Mvan_1936|M.vanbaalenii_PYR-1       HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV
MSMEG_3496|M.smegmatis_MC2_155      HWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVV
TH_3260|M.thermoresistible__bu      HWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVV
MUL_3688|M.ulcerans_Agy99           HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
Rv0402c|M.tuberculosis_H37Rv        HWLVLPMAIIVMLAVGSDYNLLLIARFQEEIGAGLKTGMIRAMAGTGRVV
MMAR_0704|M.marinum_M               HWLVLPMAIIVMLAVGSDYNLLLVARFREEIGAGLKTGMIRSMASTGRVV
                                    :::* .:::*::****:*****:::*:::*: .**:** **:*..:* **

MLBr_02378|M.leprae_Br4923          TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
MAB_3150|M.abscessus_ATCC_1997      TNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSIAA
Mb1583|M.bovis_AF2122/97            TAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV
MAV_4696|M.avium_104                TSAGLVFAATMATFMFSPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLAT
Mflv_4418|M.gilvum_PYR-GCK          TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
Mvan_1936|M.vanbaalenii_PYR-1       TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
MSMEG_3496|M.smegmatis_MC2_155      TSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAA
TH_3260|M.thermoresistible__bu      TAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIAT
MUL_3688|M.ulcerans_Agy99           TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
Rv0402c|M.tuberculosis_H37Rv        TIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRSYMTPALAT
MMAR_0704|M.marinum_M               TTAGLVFAFTMGSMLFSDLRVVGQIGTTIMIGLLFDTLVVRSFMMPAVAT
                                    * *****. **  :  * * ::.*.*:*: :***:**:::*: : *::*.

MLBr_02378|M.leprae_Br4923          LLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD--------------
MAB_3150|M.abscessus_ATCC_1997      LLGRWFWWPLRVRTHGTAGV------------------------------
Mb1583|M.bovis_AF2122/97            LLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
MAV_4696|M.avium_104                LLGRWFWWPQHVRPRPASTMLRPYGPRRAVRELILADVDEHPPGGVVQPR
Mflv_4418|M.gilvum_PYR-GCK          LLGRWFWWPQKFRSAASERRLARIGVQPATAGR-----------------
Mvan_1936|M.vanbaalenii_PYR-1       LLGRWFWWPQKVRSHASQRRLAALNH------------------------
MSMEG_3496|M.smegmatis_MC2_155      LMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV--------------
TH_3260|M.thermoresistible__bu      LLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV------------
MUL_3688|M.ulcerans_Agy99           LLGRWFWWPQVVHPRGDNARPRVAAPTH----------------------
Rv0402c|M.tuberculosis_H37Rv        LLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ-----------
MMAR_0704|M.marinum_M               LLGRWFWWPRPLAWQTRKPQMVSQRLTGVGSAKGAALLQ-----------
                                    *:*:*****