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RSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDF QQFDSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLN LTGDQGGSQANESVAAVQRIVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIA YRSLSAALIMLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATG QNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLASLTLAPAIIAVAS RFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLA SDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARVQSITRPLGAPIDHSSIPFQLGM QSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIAD FDDFWRPLRSFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQRQLLAQLDPTIA TMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFDAANNDDSFYLPPEAFQNPDFQRGLKLFLSPDG TCARFVITHRGDPASAEGISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVVAS LCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPLHWLVLPMAIIVMLAVGSDYNLL LIARFQEEIGAGLKTGMIRAMAGTGRVVTIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRS YMTPALATLLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0402c | mmpL1 | - | 100% (958) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL1 |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 57.57% (945) | transmembrane transport protein MmpL4 |
M. tuberculosis H37Rv | Rv2339 | mmpL9 | 0.0 | 56.32% (925) | transmembrane transport protein MmpL9 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 0.0 | 59.18% (931) | transmembrane transport protein MmpL6 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 56.75% (941) | transport protein |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 56.16% (917) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 55.12% (918) | MmpL family protein |
M. marinum M | MMAR_0704 | mmpL1 | 0.0 | 77.50% (951) | transmembrane transport protein MmpL1 |
M. avium 104 | MAV_4696 | - | 0.0 | 55.41% (933) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 57.02% (919) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 52.67% (936) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 55.93% (928) | transmembrane transport protein MmpL4_1 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 56.38% (940) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_02378|M.leprae_Br4923 -MTVKCAN--------------------DLDTHTKPPFVARMIHRFAVPI MAB_3150|M.abscessus_ATCC_1997 -MRHGSG-----------------------DHTARPPRIARLIRTLSIPI Mb1583|M.bovis_AF2122/97 -MSN--------------------HHRPR-------PWLPHTIRRLSLPI MAV_4696|M.avium_104 -MSEPV------------------EAAPRVDQPLIPPFLPRMIHRLALPI Mflv_4418|M.gilvum_PYR-GCK -MADAG-----------------------------RSGIGRIIRVLAVPI Mvan_1936|M.vanbaalenii_PYR-1 -MADAG-----------------------------RSGIGRIIHLLAVPI MSMEG_3496|M.smegmatis_MC2_155 -MSNP----SHDAPTD--------AMGVSGPKHARPGGIAKWIRVLAVPI TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTD--------RLDIKVSTHG-PSFISTWIRRLSLPI MUL_3688|M.ulcerans_Agy99 -MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPI Rv0402c|M.tuberculosis_H37Rv -MRSQR-------------------------LAGHLSAAARTIHALSLPI MMAR_0704|M.marinum_M -MSSLN-------------------------STGYVLGAARWVRRLSLPI :: :::** MLBr_02378|M.leprae_Br4923 ILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEG MAB_3150|M.abscessus_ATCC_1997 ILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVFGEF Mb1583|M.bovis_AF2122/97 LLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVFHEF MAV_4696|M.avium_104 VLVWLGIVFITNTVAPQLEVVAKTHSVSMSPTDAASFQSMMKVGATFKEF Mflv_4418|M.gilvum_PYR-GCK VLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEF Mvan_1936|M.vanbaalenii_PYR-1 VLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEF MSMEG_3496|M.smegmatis_MC2_155 ILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEF TH_3260|M.thermoresistible__bu IVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEG MUL_3688|M.ulcerans_Agy99 ILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFREF Rv0402c|M.tuberculosis_H37Rv ILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQF MMAR_0704|M.marinum_M VLFWVGLAVLVNVIAPQLQAVVKARSVALGPHDAPSLLAMKRIGKNFQQF :: *: : . *.*: * . : . . : .* :* : * * : MLBr_02378|M.leprae_Br4923 NSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLT MAB_3150|M.abscessus_ATCC_1997 DSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPLT Mb1583|M.bovis_AF2122/97 DSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGDPLT MAV_4696|M.avium_104 NSDNSAMILLEGDKPLGAEAHRYYDEIVRRVEQDKKHVQHVQDFWSDPLT Mflv_4418|M.gilvum_PYR-GCK DSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLT Mvan_1936|M.vanbaalenii_PYR-1 DSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPLT MSMEG_3496|M.smegmatis_MC2_155 KSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLT TH_3260|M.thermoresistible__bu SSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLT MUL_3688|M.ulcerans_Agy99 DSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRLT Rv0402c|M.tuberculosis_H37Rv DSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLT MMAR_0704|M.marinum_M ESDTIAMVVLEGQHELGEDAHRYYDRLVGKLAQDKIHVEHIDNFWGDTLT .*:. *::***:. *. *: :** :: .: * ::: : : *.* ** MLBr_02378|M.leprae_Br4923 APGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGI MAB_3150|M.abscessus_ATCC_1997 ASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAETP---GPAGV Mb1583|M.bovis_AF2122/97 AAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP---PPAGV MAV_4696|M.avium_104 AAGSQSHDQKAAYVQVYLAGNMGGGLANESALAVRKIVDSVP---APPGI Mflv_4418|M.gilvum_PYR-GCK ASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---APPGI Mvan_1936|M.vanbaalenii_PYR-1 ASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---APPGL MSMEG_3496|M.smegmatis_MC2_155 ASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---APPGV TH_3260|M.thermoresistible__bu ATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGV MUL_3688|M.ulcerans_Agy99 AAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---EPAGV Rv0402c|M.tuberculosis_H37Rv AAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVP---PPPGI MMAR_0704|M.marinum_M AASSQSADGKAAYVQLYLAGDQGGSQANESVTAVQRIIGDMP---PPPGI *.. ** * ::** : *: * : *: :*: :: * *: MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL MAB_3150|M.abscessus_ATCC_1997 QAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITTIVA Mb1583|M.bovis_AF2122/97 KAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTMVLV MAV_4696|M.avium_104 KAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSIITVAVM Mflv_4418|M.gilvum_PYR-GCK KAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLI Mvan_1936|M.vanbaalenii_PYR-1 KAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLI MSMEG_3496|M.smegmatis_MC2_155 KAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILT TH_3260|M.thermoresistible__bu QAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIA MUL_3688|M.ulcerans_Agy99 KAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVIQ Rv0402c|M.tuberculosis_H37Rv KAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIM MMAR_0704|M.marinum_M KAYLTGPGPLGADRVIYGDRSLQVITGISIAVIALMLAITYRSLWTVLFT *::** . * .. . :. .: * ..:**. : . MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT MAB_3150|M.abscessus_ATCC_1997 LLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFLL Mb1583|M.bovis_AF2122/97 LITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFVL MAV_4696|M.avium_104 LGMVFIELAAARGVVATLGNYGVMGLSTFANNMLVLMAIAAGTDYAIFVV Mflv_4418|M.gilvum_PYR-GCK LFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAI Mvan_1936|M.vanbaalenii_PYR-1 LFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAI MSMEG_3496|M.smegmatis_MC2_155 LVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLI TH_3260|M.thermoresistible__bu LFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLI MUL_3688|M.ulcerans_Agy99 LFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFLV Rv0402c|M.tuberculosis_H37Rv LLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLV MMAR_0704|M.marinum_M LLTVGIELITVRGVIAVLATNGLMDLSTFTVNVLVALAIAASTDYIIFLV * . :*::: :. ::.*:.:: .::. : ** ..** ** MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF MAB_3150|M.abscessus_ATCC_1997 GRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPLF Mb1583|M.bovis_AF2122/97 GRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPYF MAV_4696|M.avium_104 GRYHEARGLGETREQAFYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYF Mflv_4418|M.gilvum_PYR-GCK GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF Mvan_1936|M.vanbaalenii_PYR-1 GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF MSMEG_3496|M.smegmatis_MC2_155 GRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYF TH_3260|M.thermoresistible__bu GRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYF MUL_3688|M.ulcerans_Agy99 GRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPWF Rv0402c|M.tuberculosis_H37Rv GRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYF MMAR_0704|M.marinum_M GRYQESVTAGQDRELAYYTMFRGTGHVVLASGLTVAGAMYCLSFTRLPYF ***:*: : :::* : .. *:*.**:*: ** ** : *:* * MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKV-RGWRR MAB_3150|M.abscessus_ATCC_1997 RSMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPKRKYDE-GGWRR Mb1583|M.bovis_AF2122/97 QSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRT-RGWRR MAV_4696|M.avium_104 QSLGVPCAVGMLVAVLAALTLAPAMLTVASFFK-LMDPKRTLQT-RGWRR Mflv_4418|M.gilvum_PYR-GCK QTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISS-RGWRR Mvan_1936|M.vanbaalenii_PYR-1 QTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISS-RGWRR MSMEG_3496|M.smegmatis_MC2_155 QSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRT-RGWRK TH_3260|M.thermoresistible__bu QSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARV-RFWRK MUL_3688|M.ulcerans_Agy99 NTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESKRAANRGRLWRR Rv0402c|M.tuberculosis_H37Rv NTLASPCAIGLVTVMLASLTLAPAIIAVASRFG-LFDPKRATTK-RRWRR MMAR_0704|M.marinum_M QTLALPCSIGLFVVVLASLTFAPAVIVLTSRFG-AFDPKRATTT-RRWRR .::. * :: : ..*::..::: : : * ::.** **: MLBr_02378|M.leprae_Br4923 IGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGF MAB_3150|M.abscessus_ATCC_1997 IGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVGY Mb1583|M.bovis_AF2122/97 IGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGY MAV_4696|M.avium_104 MGTAVVRWPAPVLAVTIAVALVGLLALPGYKTDYDNRHFLPADTPANVGY Mflv_4418|M.gilvum_PYR-GCK IGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGY Mvan_1936|M.vanbaalenii_PYR-1 IGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGY MSMEG_3496|M.smegmatis_MC2_155 LGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGY TH_3260|M.thermoresistible__bu VGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGY MUL_3688|M.ulcerans_Agy99 VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE Rv0402c|M.tuberculosis_H37Rv IGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGY MMAR_0704|M.marinum_M IGTIVVRWPGPVLVATLLISLIGLLALPKYETNYDERHYIPAEAPSNIGY :*. :**** *:: : : ::*:::** : ..*. * ::* *:: * MLBr_02378|M.leprae_Br4923 AAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV MAB_3150|M.abscessus_ATCC_1997 AAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRV Mb1583|M.bovis_AF2122/97 MAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLV MAV_4696|M.avium_104 AAADRHFDQARLNPELLMIETDHDLRNPADFIVLDKVAKAVFHIPGIGRV Mflv_4418|M.gilvum_PYR-GCK AVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARV Mvan_1936|M.vanbaalenii_PYR-1 AVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV MSMEG_3496|M.smegmatis_MC2_155 AAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRV TH_3260|M.thermoresistible__bu EAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRV MUL_3688|M.ulcerans_Agy99 AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI Rv0402c|M.tuberculosis_H37Rv LASDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARV MMAR_0704|M.marinum_M RASDRHFPPARMEPELLMVEADHDLRNPTDMLILDRIARGIFHTPGIARV .:::** **::*::*::*::**:*:.:*:::::::*: :: *:. : MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE MAB_3150|M.abscessus_ATCC_1997 QAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQMGI Mb1583|M.bovis_AF2122/97 QAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEELGK MAV_4696|M.avium_104 QTITRPLGTPLDHSTLGFQMGAQAAGRLQTQHYQEEQANNLLKQADELRK Mflv_4418|M.gilvum_PYR-GCK QTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQT Mvan_1936|M.vanbaalenii_PYR-1 QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT MSMEG_3496|M.smegmatis_MC2_155 QAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQK TH_3260|M.thermoresistible__bu QGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQL MUL_3688|M.ulcerans_Agy99 QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV Rv0402c|M.tuberculosis_H37Rv QSITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQR MMAR_0704|M.marinum_M QGITRPLGSPIEHSSIPFQLNMQSAVTLENLSDLKERVTDLSTLTDQIQR * :*** * .:.*::: * . . .:: :: :: : MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI MAB_3150|M.abscessus_ATCC_1997 LIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFRPI Mb1583|M.bovis_AF2122/97 TIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFRPI MAV_4696|M.avium_104 TMATLHEQMQVTQDLSNTTHETTRLTKETVQITERLRDDIANFDDFLRPI Mflv_4418|M.gilvum_PYR-GCK NVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPV Mvan_1936|M.vanbaalenii_PYR-1 NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV MSMEG_3496|M.smegmatis_MC2_155 SVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPI TH_3260|M.thermoresistible__bu MIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPI MUL_3688|M.ulcerans_Agy99 LIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM Rv0402c|M.tuberculosis_H37Rv MIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPL MMAR_0704|M.marinum_M MIDITQRQEYLTRQLTEANHDVTAHTRRMEQNTNEFRDQLADFDDTWRPI : . : : .** : :** **: MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM MAB_3150|M.abscessus_ATCC_1997 RNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLM Mb1583|M.bovis_AF2122/97 RSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQ MAV_4696|M.avium_104 RSYFYWEKHCYDIPVCWALRSVFNALDGIDQVAENIVNLSANLDKLDRIQ Mflv_4418|M.gilvum_PYR-GCK RNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELM Mvan_1936|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM MSMEG_3496|M.smegmatis_MC2_155 RNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELM TH_3260|M.thermoresistible__bu RNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLM MUL_3688|M.ulcerans_Agy99 RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLT Rv0402c|M.tuberculosis_H37Rv RSFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQ MMAR_0704|M.marinum_M RNYLHWERHCFDIPICASLRSLFDAIDGVDKLSEDVGGMARATDRIDMIQ *.: :** ** .:* * : *::::::*.:: : : . : .. MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD MAB_3150|M.abscessus_ATCC_1997 PRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFD Mb1583|M.bovis_AF2122/97 PQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFD MAV_4696|M.avium_104 PKLVALIPPQIESQQRNLDTIMSNYAITQGLNDQAKAQADNATAQGDAFD Mflv_4418|M.gilvum_PYR-GCK PQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFD Mvan_1936|M.vanbaalenii_PYR-1 PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD MSMEG_3496|M.smegmatis_MC2_155 PQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFD TH_3260|M.thermoresistible__bu PQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFD MUL_3688|M.ulcerans_Agy99 SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD Rv0402c|M.tuberculosis_H37Rv RQLLAQLDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFD MMAR_0704|M.marinum_M PQLLAQLPQLIATMQTVKTLAQTLASTFSALVTQMEDMTRNSTQMGQALD ::: : : . . * * :* MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG MAB_3150|M.abscessus_ATCC_1997 EAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASVQG Mb1583|M.bovis_AF2122/97 AAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEG MAV_4696|M.avium_104 KAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVRLIISHEGDPASPEG Mflv_4418|M.gilvum_PYR-GCK DSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEG Mvan_1936|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG MSMEG_3496|M.smegmatis_MC2_155 ASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEG TH_3260|M.thermoresistible__bu QARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEG MUL_3688|M.ulcerans_Agy99 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG Rv0402c|M.tuberculosis_H37Rv AANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGDPASAEG MMAR_0704|M.marinum_M GSKNDDSFYLPPEAFQNPDFQRGLTLFLSPDGASARFVITHMGDPATAEG : *** ******.*.. ** .: *:*.** ..*: : * *:* : * MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI MAB_3150|M.abscessus_ATCC_1997 IETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAGI Mb1583|M.bovis_AF2122/97 ISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGI MAV_4696|M.avium_104 IRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLLIAGI Mflv_4418|M.gilvum_PYR-GCK ISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGI Mvan_1936|M.vanbaalenii_PYR-1 ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI MSMEG_3496|M.smegmatis_MC2_155 IKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGI TH_3260|M.thermoresistible__bu LAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAI MUL_3688|M.ulcerans_Agy99 ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV Rv0402c|M.tuberculosis_H37Rv ISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVV MMAR_0704|M.marinum_M ISHIDKIMLAADEAVKGTPLQAAHIYLAGTAATFKDIHEGTTYDLMIVVV : : *. :.:* :. : :*:.**::. :*: :* *:::. : MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL MAB_3150|M.abscessus_ATCC_1997 ASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDL Mb1583|M.bovis_AF2122/97 AALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQL MAV_4696|M.avium_104 AAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYLLGLKL Mflv_4418|M.gilvum_PYR-GCK AAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL Mvan_1936|M.vanbaalenii_PYR-1 AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL MSMEG_3496|M.smegmatis_MC2_155 AALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLEL TH_3260|M.thermoresistible__bu AAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEM MUL_3688|M.ulcerans_Agy99 SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI Rv0402c|M.tuberculosis_H37Rv ASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPL MMAR_0704|M.marinum_M AALCLIFIIMLGITRSPVASAVIVGTVALSLGSAFGLSVLIWQHILHMPL :: **::**: :* : **: *****. *:.::.*:***:** :. : : MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV MAB_3150|M.abscessus_ATCC_1997 HWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGKVV Mb1583|M.bovis_AF2122/97 YWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVV MAV_4696|M.avium_104 HWMVLAMAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVV Mflv_4418|M.gilvum_PYR-GCK HWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVV Mvan_1936|M.vanbaalenii_PYR-1 HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV MSMEG_3496|M.smegmatis_MC2_155 HWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVV TH_3260|M.thermoresistible__bu HWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVV MUL_3688|M.ulcerans_Agy99 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV Rv0402c|M.tuberculosis_H37Rv HWLVLPMAIIVMLAVGSDYNLLLIARFQEEIGAGLKTGMIRAMAGTGRVV MMAR_0704|M.marinum_M HWLVLPMAIIVMLAVGSDYNLLLVARFREEIGAGLKTGMIRSMASTGRVV :::* .:::*::****:*****:::*:::*: .**:** **:*..:* ** MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA MAB_3150|M.abscessus_ATCC_1997 TNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSIAA Mb1583|M.bovis_AF2122/97 TAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV MAV_4696|M.avium_104 TSAGLVFAATMATFMFSPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLAT Mflv_4418|M.gilvum_PYR-GCK TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA Mvan_1936|M.vanbaalenii_PYR-1 TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA MSMEG_3496|M.smegmatis_MC2_155 TSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAA TH_3260|M.thermoresistible__bu TAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIAT MUL_3688|M.ulcerans_Agy99 TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT Rv0402c|M.tuberculosis_H37Rv TIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRSYMTPALAT MMAR_0704|M.marinum_M TTAGLVFAFTMGSMLFSDLRVVGQIGTTIMIGLLFDTLVVRSFMMPAVAT * *****. ** : * * ::.*.*:*: :***:**:::*: : *::*. MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD-------------- MAB_3150|M.abscessus_ATCC_1997 LLGRWFWWPLRVRTHGTAGV------------------------------ Mb1583|M.bovis_AF2122/97 LLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR MAV_4696|M.avium_104 LLGRWFWWPQHVRPRPASTMLRPYGPRRAVRELILADVDEHPPGGVVQPR Mflv_4418|M.gilvum_PYR-GCK LLGRWFWWPQKFRSAASERRLARIGVQPATAGR----------------- Mvan_1936|M.vanbaalenii_PYR-1 LLGRWFWWPQKVRSHASQRRLAALNH------------------------ MSMEG_3496|M.smegmatis_MC2_155 LMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV-------------- TH_3260|M.thermoresistible__bu LLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV------------ MUL_3688|M.ulcerans_Agy99 LLGRWFWWPQVVHPRGDNARPRVAAPTH---------------------- Rv0402c|M.tuberculosis_H37Rv LLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ----------- MMAR_0704|M.marinum_M LLGRWFWWPRPLAWQTRKPQMVSQRLTGVGSAKGAALLQ----------- *:*:*****