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MSNHHRPRPWLPHTIRRLSLPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVFH EFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGDPLTAAGSQSTDGKAAYVQVYL AGNQGEALSIESVDAVRDIVAHTPPPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVY RSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFVLGRYHEARYAAQ DRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSR FGCFEPKRRMRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGYMAA ERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQ SVGQIQNLKYQRDRAADLLKQAEELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANF DDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGK AARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAAL SLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLL ISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAF MTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1583 | mmpL6 | - | 100% (967) | transmembrane transport protein MmpL6 |
| M. bovis AF2122 / 97 | Mb0519 | mmpL2 | 0.0 | 64.01% (953) | transmembrane transport protein MmpL2 |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 61.09% (951) | transmembrane transport protein MmpL4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 61.83% (938) | transport protein |
| M. tuberculosis H37Rv | Rv0507 | mmpL2 | 0.0 | 64.11% (953) | transmembrane transport protein MmpL2 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 60.95% (945) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_0987c | - | 0.0 | 67.72% (945) | membrane protein MmpL |
| M. marinum M | MMAR_0775 | - | 0.0 | 65.34% (955) | MmpL family transport protein |
| M. avium 104 | MAV_3863 | - | 0.0 | 75.03% (957) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 60.58% (936) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 57.65% (935) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 60.30% (942) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 61.76% (931) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3496|M.smegmatis_MC2_155 -MSNP----SHDAPTDAMGVSGPKHAR------------------PGGIA
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHG-------------------PSFIS
MUL_0757|M.ulcerans_Agy99 MTATT-----TDTPTDVVPP--AEHPP------------------RPFIP
Mflv_4418|M.gilvum_PYR-GCK ----------------------MADAG------------------RSGIG
Mvan_1936|M.vanbaalenii_PYR-1 ----------------------MADAG------------------RSGIG
MLBr_02378|M.leprae_Br4923 -------------MTVKCANDLDTHTK------------------PPFVA
Rv0507|M.tuberculosis_H37Rv -------------MSERHAALTSLP---------------------PILP
MMAR_0775|M.marinum_M -------MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMA
Mb1583|M.bovis_AF2122/97 -------------MSNHHRP-------------------------RPWLP
MAV_3863|M.avium_104 -------------MTTDQAT-------------------------RSVVA
MAB_0987c|M.abscessus_ATCC_199 -------------MSANHAH-------------------------ESRAA
MSMEG_3496|M.smegmatis_MC2_155 KWIRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAM
TH_3260|M.thermoresistible__bu TWIRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAM
MUL_0757|M.ulcerans_Agy99 RMIRTFAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISM
Mflv_4418|M.gilvum_PYR-GCK RIIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSM
Mvan_1936|M.vanbaalenii_PYR-1 RIIHLLAVPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSM
MLBr_02378|M.leprae_Br4923 RMIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAM
Rv0507|M.tuberculosis_H37Rv RLIRRFAVVIVLLWLGFTAFVNLAVPQLEVVGKAHSVSMSPSDAASIQAI
MMAR_0775|M.marinum_M RLIHRMAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAM
Mb1583|M.bovis_AF2122/97 HTIRRLSLPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAM
MAV_3863|M.avium_104 QTIRRLSVPILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAM
MAB_0987c|M.abscessus_ATCC_199 KIVRRLAVPIVLFWVAIAAVTNATVPQLEVVGEERSAPLNAADAPSTLAM
:: ::: ::: *: . . :*.*: *.: : . .. * ::
MSMEG_3496|M.smegmatis_MC2_155 KRVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEH
TH_3260|M.thermoresistible__bu KRVGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVEN
MUL_0757|M.ulcerans_Agy99 KHIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQS
Mflv_4418|M.gilvum_PYR-GCK KRVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQH
Mvan_1936|M.vanbaalenii_PYR-1 ERVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQH
MLBr_02378|M.leprae_Br4923 QKMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQS
Rv0507|M.tuberculosis_H37Rv KRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAH
MMAR_0775|M.marinum_M KRVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQH
Mb1583|M.bovis_AF2122/97 KRIGKVFHEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEH
MAV_3863|M.avium_104 QHIGKVFHEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEH
MAB_0987c|M.abscessus_ATCC_199 RHIGKVFNEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHVQH
.::* * * .::. :****:.*** *: :*. :: .* * :*
MSMEG_3496|M.smegmatis_MC2_155 VQDFWGDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVES
TH_3260|M.thermoresistible__bu VQDLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIAT
MUL_0757|M.ulcerans_Agy99 VQDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDS
Mflv_4418|M.gilvum_PYR-GCK IADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDR
Mvan_1936|M.vanbaalenii_PYR-1 VADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQ
MLBr_02378|M.leprae_Br4923 VQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQ
Rv0507|M.tuberculosis_H37Rv IQDFWGDPLTAAGSQSADDRAAYVVVYLVGNN-ETEAYDSVHAVRHMVDT
MMAR_0775|M.marinum_M VQDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVND
Mb1583|M.bovis_AF2122/97 VQDFWGDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAH
MAV_3863|M.avium_104 VQNFWGDPLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEH
MAB_0987c|M.abscessus_ATCC_199 VADYWGDPITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRIIAE
: : *.**:** * ** *. ::** **: : : ::: ::: ::
MSMEG_3496|M.smegmatis_MC2_155 VP---APPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLV
TH_3260|M.thermoresistible__bu VSEEMAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFV
MUL_0757|M.ulcerans_Agy99 LQ---APPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLV
Mflv_4418|M.gilvum_PYR-GCK TP---APPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIV
Mvan_1936|M.vanbaalenii_PYR-1 TP---APPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLV
MLBr_02378|M.leprae_Br4923 TP---APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLV
Rv0507|M.tuberculosis_H37Rv TP---PPHGVKAYVTGPAALNADQAEAGDKSIAKVTAITSMVIAAMLLVI
MMAR_0775|M.marinum_M TP---APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSV
Mb1583|M.bovis_AF2122/97 TP---PPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFV
MAV_3863|M.avium_104 TP---PPPGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWV
MAB_0987c|M.abscessus_ATCC_199 TP---APDGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVV
.* *: .:*:* :. :* .. . : : ** . ** :
MSMEG_3496|M.smegmatis_MC2_155 YRSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIA
TH_3260|M.thermoresistible__bu YRSVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIA
MUL_0757|M.ulcerans_Agy99 YRSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIA
Mflv_4418|M.gilvum_PYR-GCK FRSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIA
Mvan_1936|M.vanbaalenii_PYR-1 FRSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIA
MLBr_02378|M.leprae_Br4923 YRSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIA
Rv0507|M.tuberculosis_H37Rv YRSVITAVLVLIMVGIDLGAIRGFIALLADHNIFSLSTFATNLLVLMAIA
MMAR_0775|M.marinum_M YRSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIA
Mb1583|M.bovis_AF2122/97 YRSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIA
MAV_3863|M.avium_104 YRS-VTAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIA
MAB_0987c|M.abscessus_ATCC_199 YRSLITTALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIA
:** * * * . ** :* *. ::.**.::..**. :.**
MSMEG_3496|M.smegmatis_MC2_155 AATDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATL
TH_3260|M.thermoresistible__bu IAVDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATF
MUL_0757|M.ulcerans_Agy99 AATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATF
Mflv_4418|M.gilvum_PYR-GCK AGTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAML
Mvan_1936|M.vanbaalenii_PYR-1 AGTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAML
MLBr_02378|M.leprae_Br4923 AGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATF
Rv0507|M.tuberculosis_H37Rv ASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILGSGLTIAGAMY
MMAR_0775|M.marinum_M AGTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMY
Mb1583|M.bovis_AF2122/97 AGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVY
MAV_3863|M.avium_104 AGTDYAIFFVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVL
MAB_0987c|M.abscessus_ATCC_199 AGTDYAIFFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALF
..**.** ***:*:* .: :: **: .* **::.**:*::**
MSMEG_3496|M.smegmatis_MC2_155 CLHFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKR
TH_3260|M.thermoresistible__bu CLSFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKR
MUL_0757|M.ulcerans_Agy99 CLSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKR
Mflv_4418|M.gilvum_PYR-GCK CLSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKR
Mvan_1936|M.vanbaalenii_PYR-1 CLSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKR
MLBr_02378|M.leprae_Br4923 CLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKR
Rv0507|M.tuberculosis_H37Rv CLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFK-LFDPKR
MMAR_0775|M.marinum_M CLSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKR
Mb1583|M.bovis_AF2122/97 CLSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKR
MAV_3863|M.avium_104 CLRFTRLNYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKR
MAB_0987c|M.abscessus_ATCC_199 CLSFTRLPYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKR
** *:*: **:::* * ::* : : .:*:: .::: : * ::***
MSMEG_3496|M.smegmatis_MC2_155 AMRTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLP
TH_3260|M.thermoresistible__bu AARVRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLP
MUL_0757|M.ulcerans_Agy99 MARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLP
Mflv_4418|M.gilvum_PYR-GCK AISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLP
Mvan_1936|M.vanbaalenii_PYR-1 AISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLP
MLBr_02378|M.leprae_Br4923 LIKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLP
Rv0507|M.tuberculosis_H37Rv RMNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYDLRKFMP
MMAR_0775|M.marinum_M KMRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLP
Mb1583|M.bovis_AF2122/97 RMRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMP
MAV_3863|M.avium_104 QMATRGWRRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMP
MAB_0987c|M.abscessus_ATCC_199 AMRTRGWRRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMP
* **::*. :**** *:: : : :**::**.*:*.*. : ::*
MSMEG_3496|M.smegmatis_MC2_155 QDLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRV
TH_3260|M.thermoresistible__bu ASFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAV
MUL_0757|M.ulcerans_Agy99 ADLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAI
Mflv_4418|M.gilvum_PYR-GCK EDIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSV
Mvan_1936|M.vanbaalenii_PYR-1 EDVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAI
MLBr_02378|M.leprae_Br4923 ASIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGI
Rv0507|M.tuberculosis_H37Rv ASMPSNVGDAAAGRRFSRARLNPEVLLIETDHDMRNPVDMLVLDKVAKNI
MMAR_0775|M.marinum_M ASTPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGV
Mb1583|M.bovis_AF2122/97 ATAPANIGYMAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAV
MAV_3863|M.avium_104 ASAPANTGYTAAERHFSQARLNPELLMIETDHDMRNPADMINLERVAKAI
MAB_0987c|M.abscessus_ATCC_199 SSVPSNVGYAAAERHFSVARLNPELLMIETDFDMRNPAGMVLLERVAKSV
*:* * .* ::* **::**:*::*:*.*:**. .:: ::::*: :
MSMEG_3496|M.smegmatis_MC2_155 FQVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADM
TH_3260|M.thermoresistible__bu FQVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADM
MUL_0757|M.ulcerans_Agy99 FGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSM
Mflv_4418|M.gilvum_PYR-GCK FRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADM
Mvan_1936|M.vanbaalenii_PYR-1 FRVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADM
MLBr_02378|M.leprae_Br4923 FRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDL
Rv0507|M.tuberculosis_H37Rv YHSPGIEQVKAITRPLGTTIKHTSIPFIISMQGVNSSEQMEFMKDRIDDI
MMAR_0775|M.marinum_M FHLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADM
Mb1583|M.bovis_AF2122/97 FHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADL
MAV_3863|M.avium_104 AHLPGIAQVQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDL
MAB_0987c|M.abscessus_ATCC_199 LHARGVALVQSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYL
*: *: :*** *..: *:::.* :* . . . :: :
MSMEG_3496|M.smegmatis_MC2_155 LVMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIA
TH_3260|M.thermoresistible__bu LVQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSIS
MUL_0757|M.ulcerans_Agy99 LQQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIA
Mflv_4418|M.gilvum_PYR-GCK LVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLA
Mvan_1936|M.vanbaalenii_PYR-1 LVQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLA
MLBr_02378|M.leprae_Br4923 LRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIA
Rv0507|M.tuberculosis_H37Rv LVQVAAMNTSIETMHRMYALMGEVIDNTVDMDHLTHDMSDITATLRDHLA
MMAR_0775|M.marinum_M LIQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIA
Mb1583|M.bovis_AF2122/97 LKQAEELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIA
MAV_3863|M.avium_104 LKQADNLKDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIA
MAB_0987c|M.abscessus_ATCC_199 SQQADQMTNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIA
. : : : . : * :*: ::
MSMEG_3496|M.smegmatis_MC2_155 DFDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMP
TH_3260|M.thermoresistible__bu EFDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLP
MUL_0757|M.ulcerans_Agy99 DFDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLP
Mflv_4418|M.gilvum_PYR-GCK DFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIP
Mvan_1936|M.vanbaalenii_PYR-1 NLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIP
MLBr_02378|M.leprae_Br4923 NFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVG
Rv0507|M.tuberculosis_H37Rv DFEDFFRPIRSYFYWEKHCFDVPLCWSIRSIFDMFDSVDQLSEKLEYLVK
MMAR_0775|M.marinum_M DFDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSR
Mb1583|M.bovis_AF2122/97 NFDDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTV
MAV_3863|M.avium_104 NFDDFFRPVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTA
MAB_0987c|M.abscessus_ATCC_199 NFDDQFRPIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTG
:::* **:*.***** ** .:* * ::**:** :*.:: : : :
MSMEG_3496|M.smegmatis_MC2_155 DMDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMEN
TH_3260|M.thermoresistible__bu HMHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQEN
MUL_0757|M.ulcerans_Agy99 LMERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQED
Mflv_4418|M.gilvum_PYR-GCK DLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSED
Mvan_1936|M.vanbaalenii_PYR-1 DLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSED
MLBr_02378|M.leprae_Br4923 DIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDN
Rv0507|M.tuberculosis_H37Rv DMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHGTLGAFYKQQERNNKD
MMAR_0775|M.marinum_M DMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKN
Mb1583|M.bovis_AF2122/97 TLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIEN
MAV_3863|M.avium_104 SLDKLDAGQQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDT
MAB_0987c|M.abscessus_ATCC_199 SLTKLDALQPKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRT
: : :: :* : * . *
MSMEG_3496|M.smegmatis_MC2_155 QTAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISH
TH_3260|M.thermoresistible__bu ANAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISH
MUL_0757|M.ulcerans_Agy99 SSAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISH
Mflv_4418|M.gilvum_PYR-GCK ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISH
Mvan_1936|M.vanbaalenii_PYR-1 ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAH
MLBr_02378|M.leprae_Br4923 ANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILH
Rv0507|M.tuberculosis_H37Rv PGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAARFVIAL
MMAR_0775|M.marinum_M STAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISH
Mb1583|M.bovis_AF2122/97 AAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISH
MAV_3863|M.avium_104 ATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISH
MAB_0987c|M.abscessus_ATCC_199 ATELGKAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITH
:*..:* : *****:* ..* * *:*.:: *:*.**::.*::*
MSMEG_3496|M.smegmatis_MC2_155 EGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGA
TH_3260|M.thermoresistible__bu QGDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGT
MUL_0757|M.ulcerans_Agy99 EGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGN
Mflv_4418|M.gilvum_PYR-GCK EGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGA
Mvan_1936|M.vanbaalenii_PYR-1 EGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGA
MLBr_02378|M.leprae_Br4923 RGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGA
Rv0507|M.tuberculosis_H37Rv EGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGA
MMAR_0775|M.marinum_M EGDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGS
Mb1583|M.bovis_AF2122/97 EGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGA
MAV_3863|M.avium_104 EGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGA
MAB_0987c|M.abscessus_ATCC_199 QGDPQTSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQ
.*** : *: : * * :*:* **: .: :*:.**.: :**: :*
MSMEG_3496|M.smegmatis_MC2_155 NYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLI
TH_3260|M.thermoresistible__bu KYDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLI
MUL_0757|M.ulcerans_Agy99 TFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLI
Mflv_4418|M.gilvum_PYR-GCK FYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLL
Mvan_1936|M.vanbaalenii_PYR-1 NYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLL
MLBr_02378|M.leprae_Br4923 NWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLL
Rv0507|M.tuberculosis_H37Rv RYDLLIAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLV
MMAR_0775|M.marinum_M RWDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLV
Mb1583|M.bovis_AF2122/97 TYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLV
MAV_3863|M.avium_104 KYDLLIAGIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLV
MAB_0987c|M.abscessus_ATCC_199 KYDLLMAALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVV
:**::*.:::: **::**:.:**:.**: ****** :*:.****:**::
MSMEG_3496|M.smegmatis_MC2_155 WQHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIR
TH_3260|M.thermoresistible__bu WQYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIR
MUL_0757|M.ulcerans_Agy99 WQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIR
Mflv_4418|M.gilvum_PYR-GCK WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIR
Mvan_1936|M.vanbaalenii_PYR-1 WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIR
MLBr_02378|M.leprae_Br4923 WQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIR
Rv0507|M.tuberculosis_H37Rv WQDILGIELYWMVLAMSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIR
MMAR_0775|M.marinum_M WQDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIR
Mb1583|M.bovis_AF2122/97 WQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIR
MAV_3863|M.avium_104 WQDILGIKLYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIR
MAB_0987c|M.abscessus_ATCC_199 WQYIFGIPLYWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIR
** :.*: :::: :.:::*:*****:*****:::*:::* .*::**:**
MSMEG_3496|M.smegmatis_MC2_155 SMGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIR
TH_3260|M.thermoresistible__bu AMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVR
MUL_0757|M.ulcerans_Agy99 AMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVR
Mflv_4418|M.gilvum_PYR-GCK AMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
Mvan_1936|M.vanbaalenii_PYR-1 SMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
MLBr_02378|M.leprae_Br4923 SMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVR
Rv0507|M.tuberculosis_H37Rv AMAGTGGVVTAAGMVFAVTMSLFVFSDLRIIGQIGTTIGLGLLFDTLVVR
MMAR_0775|M.marinum_M AMAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVR
Mb1583|M.bovis_AF2122/97 AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR
MAV_3863|M.avium_104 SMAGSGAVVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVR
MAB_0987c|M.abscessus_ATCC_199 AIAGTGGVVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR
::.*:* *** **:**. ** : :.* ::.*:****.:******:::*
MSMEG_3496|M.smegmatis_MC2_155 SFMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV-----
TH_3260|M.thermoresistible__bu SFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV---
MUL_0757|M.ulcerans_Agy99 SFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------
Mflv_4418|M.gilvum_PYR-GCK SFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR--------
Mvan_1936|M.vanbaalenii_PYR-1 SFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH---------------
MLBr_02378|M.leprae_Br4923 SFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD-----
Rv0507|M.tuberculosis_H37Rv SFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAPRRLVRALLLP----S
MMAR_0775|M.marinum_M SFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDS
Mb1583|M.bovis_AF2122/97 AFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND-
MAV_3863|M.avium_104 SFMTPSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDP
MAB_0987c|M.abscessus_ATCC_199 SFLTPAIATMLGRWFWWPINIRTRPAP---KPFGPKPTG--------ADD
:*: *::*.::*:***** * .
MSMEG_3496|M.smegmatis_MC2_155 -------------------
TH_3260|M.thermoresistible__bu -------------------
MUL_0757|M.ulcerans_Agy99 -------------------
Mflv_4418|M.gilvum_PYR-GCK -------------------
Mvan_1936|M.vanbaalenii_PYR-1 -------------------
MLBr_02378|M.leprae_Br4923 -------------------
Rv0507|M.tuberculosis_H37Rv GQHPSATGAHE--------
MMAR_0775|M.marinum_M ADGPEDTNTERLAVSSPHY
Mb1583|M.bovis_AF2122/97 --DPRTQVATHR-------
MAV_3863|M.avium_104 AVAPETPSAARHSRG----
MAB_0987c|M.abscessus_ATCC_199 TTGPIPVSG----------