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MVPGEVHMSDTPSGPHPIIPRTIRLAAIPILLCWLGFTVFVSVAVPPLEAIGETRAVAVAPDDAQSMRAM RRAGKVFNEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQDFWRDPLTAAGAVSADGK AAYVQLYLAGNMGEALANESVEAVRKIVANSTPPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVI TVLLLLVYRSIATTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAGTDYAIFLVGRY QEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCLSFARLTLFHTMGPPLAIGMLVSVAAALTLAP AIIAIAGRFGLLDPKRRLKTRGWRRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAGTP VNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLVIDKIAKEVLHVSGVERVQAITRPQGVPLEHAS IPFQISMMGATQTMSLPYMRERMADMLTMSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSE LRDHLADIDDFVRPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDMNKMEALTPQFLA LLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHATAMGQAFDTAKSGDSFYLPPEAFDNAEFQQGMK LFLSPNGKAVRFVISHESDPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKYDI LIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQHFVGLQVHWTIVAMSVIVLLAV GSDYNLLLVSRFKEEVGAGLKTGIIRAMAGTGAVVTSAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLF DTLVVRSFMTPSIAALLGRWFWWPNMIHSRPTVPEAHTRQGARRIQPHLHRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2339 | mmpL9 | - | 100% (962) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL9 |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 61.64% (941) | transmembrane transport protein MmpL4 |
| M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 61.45% (926) | transmembrane transport protein MmpL5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2367 | mmpL9a | 0.0 | 99.88% (826) | transmembrane transport protein MmpL9A |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 60.36% (946) | transport protein |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.34% (937) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_4746 | - | 0.0 | 56.83% (959) | putative membrane protein, MmpL |
| M. marinum M | MMAR_0775 | - | 0.0 | 61.79% (929) | MmpL family transport protein |
| M. avium 104 | MAV_2510 | - | 0.0 | 60.68% (936) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 62.12% (924) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 56.90% (956) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 60.24% (928) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 60.42% (945) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2339|M.tuberculosis_H37Rv ------MVPGEVHMS-----------------DTPSGPHP-----IIPRT
Mb2367|M.bovis_AF2122/97 ------MVPGEVHMS-----------------DTPSGPHP-----IIPRT
Mflv_3435|M.gilvum_PYR-GCK ------MSAPVSDAR-----------TDEFPAAHGPHRS------FIPRM
Mvan_3189|M.vanbaalenii_PYR-1 ------MSAPVSDAR-----------TDEFPAARQPHRP------FIPRM
TH_3260|M.thermoresistible__bu ------MTANPGHVR-----------TDEAPTDRLDIKVSTHGPSFISTW
MUL_0757|M.ulcerans_Agy99 ------MTATTTDTP-----------TDVVPPAEHPPRP------FIPRM
MAV_2510|M.avium_104 ------MSTTFDDTR-----------TDAIPVV--KEPVR----EKIPRF
MSMEG_3496|M.smegmatis_MC2_155 ------MSNPSHDAP-----------TDAMGVSGPKHARP----GGIAKW
MLBr_02378|M.leprae_Br4923 ------MTVKCAN------------------DLDTHTKPP-----FVARM
MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRP-----SMARL
MAB_4746|M.abscessus_ATCC_1997 ------MSGESRVSA-------------------PAPERP-----AFMRF
: .
Rv2339|M.tuberculosis_H37Rv IRLAAIPILLCWLGFTVFVSVAVPPLEAIGETRAVAVAPDDAQSMRAMRR
Mb2367|M.bovis_AF2122/97 IRLAAIPILLCWLGFTVFVSVVVPPLEAIGETRAVAVAPDDAQSMRAMRR
Mflv_3435|M.gilvum_PYR-GCK IRLFAVPIILGWIALIVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKK
Mvan_3189|M.vanbaalenii_PYR-1 IRLFAVPIILGWIALIVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKK
TH_3260|M.thermoresistible__bu IRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKR
MUL_0757|M.ulcerans_Agy99 IRTFAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKH
MAV_2510|M.avium_104 IRAFAVPIIIGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKR
MSMEG_3496|M.smegmatis_MC2_155 IRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKR
MLBr_02378|M.leprae_Br4923 IHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQK
MMAR_0775|M.marinum_M IHRMAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKR
MAB_4746|M.abscessus_ATCC_1997 VRRFAVPILTTWLFMTVAVNVLVPPIESVAREHAVTMSPHDAPAMIAAKH
:: ::*:: *: : . : :* :: :.. ::* ::* * : : ::
Rv2339|M.tuberculosis_H37Rv AGKVFNEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQ
Mb2367|M.bovis_AF2122/97 AGKVFNEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQ
Mflv_3435|M.gilvum_PYR-GCK VGELFEEGDSDSSVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQ
Mvan_3189|M.vanbaalenii_PYR-1 VGELFREGDSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQ
TH_3260|M.thermoresistible__bu VGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQ
MUL_0757|M.ulcerans_Agy99 IGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQ
MAV_2510|M.avium_104 MGAVFNEYKSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQ
MSMEG_3496|M.smegmatis_MC2_155 VGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQ
MLBr_02378|M.leprae_Br4923 MGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQ
MMAR_0775|M.marinum_M VGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQ
MAB_4746|M.abscessus_ATCC_1997 IGQKYHESDSDSIAMIVLESDDPLGERAHQYYDNLVLALQADTRHVQHVQ
* : * .::* *:*:*.:.*** *: :** :: * * *:: :*
Rv2339|M.tuberculosis_H37Rv DFWRDPLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEAVRKIVANST
Mb2367|M.bovis_AF2122/97 DFWRDPLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEAVRKIVANST
Mflv_3435|M.gilvum_PYR-GCK DFWSDPLTASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE
Mvan_3189|M.vanbaalenii_PYR-1 DFWSDPLTASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE
TH_3260|M.thermoresistible__bu DLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVS
MUL_0757|M.ulcerans_Agy99 DFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ
MAV_2510|M.avium_104 DMWSDPLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSVQ
MSMEG_3496|M.smegmatis_MC2_155 DFWGDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP
MLBr_02378|M.leprae_Br4923 DFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP
MMAR_0775|M.marinum_M DFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP
MAB_4746|M.abscessus_ATCC_1997 NVWGDPLTASGVQSRDGRAAYVQVNLAGDQGSTLGNKSVVAVREIVDNST
:.* ****..* * ** ::*** *: *. .::*: :.: :
Rv2339|M.tuberculosis_H37Rv ---PPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYR
Mb2367|M.bovis_AF2122/97 ---PPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYR
Mflv_3435|M.gilvum_PYR-GCK ---PPPGVRAFVTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYR
Mvan_3189|M.vanbaalenii_PYR-1 ---PPPGVRAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYR
TH_3260|M.thermoresistible__bu EEMAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYR
MUL_0757|M.ulcerans_Agy99 ---APPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYR
MAV_2510|M.avium_104 ---APNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYR
MSMEG_3496|M.smegmatis_MC2_155 ---APPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYR
MLBr_02378|M.leprae_Br4923 ---APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYR
MMAR_0775|M.marinum_M ---APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYR
MAB_4746|M.abscessus_ATCC_1997 ---PPQGVTVYVTGPAALTTDMNEAADKSMLIMMGVTGAVIMIMLLITYR
.* *: .:*** :*: :* :.* *: : : ** ** .**
Rv2339|M.tuberculosis_H37Rv SIATTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAG
Mb2367|M.bovis_AF2122/97 SIATTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAG
Mflv_3435|M.gilvum_PYR-GCK SIVTVLITLVMVVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAA
Mvan_3189|M.vanbaalenii_PYR-1 SIVTVLLTLVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAA
TH_3260|M.thermoresistible__bu SVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIA
MUL_0757|M.ulcerans_Agy99 SIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAA
MAV_2510|M.avium_104 SVITVLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAA
MSMEG_3496|M.smegmatis_MC2_155 SIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAA
MLBr_02378|M.leprae_Br4923 SFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAG
MMAR_0775|M.marinum_M SLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAG
MAB_4746|M.abscessus_ATCC_1997 SVSTMLLVLVMVGFEMGTARGIVAILGNYDLLGFSTFVVAMLSSLAIAAG
*. * * * : .:** :*:*. ::*:* *.. :* :*** .
Rv2339|M.tuberculosis_H37Rv TDYAIFLVGRYQEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCL
Mb2367|M.bovis_AF2122/97 TDYAIFLVGRYQEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCL
Mflv_3435|M.gilvum_PYR-GCK TDYAIFLIGRYQEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCL
Mvan_3189|M.vanbaalenii_PYR-1 TDYAIFLIGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCL
TH_3260|M.thermoresistible__bu VDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCL
MUL_0757|M.ulcerans_Agy99 TDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCL
MAV_2510|M.avium_104 TDYAIFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCL
MSMEG_3496|M.smegmatis_MC2_155 TDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCL
MLBr_02378|M.leprae_Br4923 TDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCL
MMAR_0775|M.marinum_M TDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCL
MAB_4746|M.abscessus_ATCC_1997 TDYAIFLIGRYQEARQVGQDRENAYYTMFRGTFHIILGSGLTIAGATLCL
.**.**: ******* . .: :::**: .* ::: .**:**:** **
Rv2339|M.tuberculosis_H37Rv SFARLTLFHTMGPPLAIGMLVSVAAALTLAPAIIAIAGRFG-LLDPKRRL
Mb2367|M.bovis_AF2122/97 SFARLTLFHTMGPPLAIGMLVSVAAALTLAPAIIAIAGRFG-LLDPKRRL
Mflv_3435|M.gilvum_PYR-GCK SFTRLPYFQTMGVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAM
Mvan_3189|M.vanbaalenii_PYR-1 SFTRLPYFQTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAM
TH_3260|M.thermoresistible__bu SFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAA
MUL_0757|M.ulcerans_Agy99 SFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMA
MAV_2510|M.avium_104 HFTNLPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQ
MSMEG_3496|M.smegmatis_MC2_155 HFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAM
MLBr_02378|M.leprae_Br4923 SFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLI
MMAR_0775|M.marinum_M SFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKM
MAB_4746|M.abscessus_ATCC_1997 HLARLSYFKALGIPSALGLLVVVVGALTAAPAVVVVAGRFG-LLDPKRPV
::.:. *:::* * *:*: : : .: * : : * ::*:*
Rv2339|M.tuberculosis_H37Rv KTRGWRRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAG
Mb2367|M.bovis_AF2122/97 KTRGWRRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAG
Mflv_3435|M.gilvum_PYR-GCK RIRGWRKIGAAIVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPAD
Mvan_3189|M.vanbaalenii_PYR-1 RIRGWRKIGAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPAD
TH_3260|M.thermoresistible__bu RVRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPAS
MUL_0757|M.ulcerans_Agy99 RVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPAD
MAV_2510|M.avium_104 RIRGWRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTD
MSMEG_3496|M.smegmatis_MC2_155 RTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQD
MLBr_02378|M.leprae_Br4923 KVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPAS
MMAR_0775|M.marinum_M RTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPAS
MAB_4746|M.abscessus_ATCC_1997 NVRRWRRIGTATVRWPGAVFAASSAIALVGIAIMPTMKVSYNDRFYIPED
. * **::*: **** .:: : .::::*: :* : .*..: *: .
Rv2339|M.tuberculosis_H37Rv TPVNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLVIDKIAKEVLH
Mb2367|M.bovis_AF2122/97 TPVNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLVIDKIAKEVLH
Mflv_3435|M.gilvum_PYR-GCK LPANQGYAVADEHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFR
Mvan_3189|M.vanbaalenii_PYR-1 LPANEGYAVADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFK
TH_3260|M.thermoresistible__bu FPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQ
MUL_0757|M.ulcerans_Agy99 LPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFG
MAV_2510|M.avium_104 LPANEGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFR
MSMEG_3496|M.smegmatis_MC2_155 LPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQ
MLBr_02378|M.leprae_Br4923 IPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFR
MMAR_0775|M.marinum_M TPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFH
MAB_4746|M.abscessus_ATCC_1997 LPSNIGYTAAERHFSSATMNPDILMIESDHDMRNTGDMIILDRIAKEVFR
* * *: .*:.** * ::*::*::*:*:*:**...:::::::*: ::
Rv2339|M.tuberculosis_H37Rv VSGVERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADMLT
Mb2367|M.bovis_AF2122/97 VSGVERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADMLT
Mflv_3435|M.gilvum_PYR-GCK VEGIARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLV
Mvan_3189|M.vanbaalenii_PYR-1 VEGIARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLV
TH_3260|M.thermoresistible__bu VEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLV
MUL_0757|M.ulcerans_Agy99 VEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQ
MAV_2510|M.avium_104 VPGIGRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLH
MSMEG_3496|M.smegmatis_MC2_155 VPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLV
MLBr_02378|M.leprae_Br4923 VPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLR
MMAR_0775|M.marinum_M LPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLI
MAB_4746|M.abscessus_ATCC_1997 SPGIAMVQSITRPLGGPIEHTSIPFQISAQSIPIQQNLQFMKDRAADMLS
*: **.:*** * .:.*:**** :* . . : :: .:*
Rv2339|M.tuberculosis_H37Rv MSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADI
Mb2367|M.bovis_AF2122/97 MSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADI
Mflv_3435|M.gilvum_PYR-GCK QADEMANTIKTMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANF
Mvan_3189|M.vanbaalenii_PYR-1 QADEMANTIATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANF
TH_3260|M.thermoresistible__bu QADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEF
MUL_0757|M.ulcerans_Agy99 QVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADF
MAV_2510|M.avium_104 QADMMQTTIDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADF
MSMEG_3496|M.smegmatis_MC2_155 MADEMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADF
MLBr_02378|M.leprae_Br4923 QAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANF
MMAR_0775|M.marinum_M QAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADF
MAB_4746|M.abscessus_ATCC_1997 MSKDLDALIGAMERMQSLLGQMSSATHRMSANMTDAKTTLEEIRDHLADF
: : : .* : : . . : .:*: ::::
Rv2339|M.tuberculosis_H37Rv DDFVRPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDM
Mb2367|M.bovis_AF2122/97 DDFVRPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDM
Mflv_3435|M.gilvum_PYR-GCK DDFFRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDM
Mvan_3189|M.vanbaalenii_PYR-1 DDFFRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDM
TH_3260|M.thermoresistible__bu DDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHM
MUL_0757|M.ulcerans_Agy99 DDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLM
MAV_2510|M.avium_104 EDFFRPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIM
MSMEG_3496|M.smegmatis_MC2_155 DDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDM
MLBr_02378|M.leprae_Br4923 DDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDI
MMAR_0775|M.marinum_M DDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDM
MAB_4746|M.abscessus_ATCC_1997 DDVVRPLRNYFYWEQHCFDLPACSAIRSVFDALDGVDAFSDKMRALTTDI
:*. **:*.***** ** .:* * : **:**:***:: : : : : :
Rv2339|M.tuberculosis_H37Rv NKMEALTPQFLALLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHAT
Mb2367|M.bovis_AF2122/97 NKMEALTPQFLALLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHAT
Mflv_3435|M.gilvum_PYR-GCK KRLDTLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDAD
Mvan_3189|M.vanbaalenii_PYR-1 KRLDSLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDAD
TH_3260|M.thermoresistible__bu HRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENAN
MUL_0757|M.ulcerans_Agy99 ERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSS
MAV_2510|M.avium_104 DHLDTLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSN
MSMEG_3496|M.smegmatis_MC2_155 DRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQT
MLBr_02378|M.leprae_Br4923 KNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNAN
MMAR_0775|M.marinum_M DRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNST
MAB_4746|M.abscessus_ATCC_1997 GNVDAVIPQMAAQLPPIIAVARSMQDTLLTMHSSFSNLITQMAHMTDTAS
.:: : **: :* : .:*: :*: : . * .
Rv2339|M.tuberculosis_H37Rv AMGQAFDTAKSGDSFYLPPEAFDNAEFQQGMKLFLSPNGKAVRFVISHES
Mb2367|M.bovis_AF2122/97 AMGQAFDTAKSGDSFYLPPEAFDNAEFQQGMKLFLSPNGKAVRFVISHES
Mflv_3435|M.gilvum_PYR-GCK AMGEAFDDSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEG
Mvan_3189|M.vanbaalenii_PYR-1 AMGEAFDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEG
TH_3260|M.thermoresistible__bu AMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQG
MUL_0757|M.ulcerans_Agy99 AMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEG
MAV_2510|M.avium_104 AMGKAFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDG
MSMEG_3496|M.smegmatis_MC2_155 AMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEG
MLBr_02378|M.leprae_Br4923 TMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRG
MMAR_0775|M.marinum_M AMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEG
MAB_4746|M.abscessus_ATCC_1997 AMGQAFDASRSGDYFYLPPEAFQNPDFQRGLKLFLSPDGTAARFIITHDR
:**:*** : ..* **:*** *.* :*::.:: *:*.:* *.**:* *
Rv2339|M.tuberculosis_H37Rv DPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKY
Mb2367|M.bovis_AF2122/97 DPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKY
Mflv_3435|M.gilvum_PYR-GCK DPLSPEGVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNY
Mvan_3189|M.vanbaalenii_PYR-1 DPLSPEGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNY
TH_3260|M.thermoresistible__bu DPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKY
MUL_0757|M.ulcerans_Agy99 DPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTF
MAV_2510|M.avium_104 DPMTQEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNY
MSMEG_3496|M.smegmatis_MC2_155 DPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANY
MLBr_02378|M.leprae_Br4923 DPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANW
MMAR_0775|M.marinum_M DPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRW
MAB_4746|M.abscessus_ATCC_1997 DPATPAGISTVTSELEAAHQAVKGTALTDAKFYLAGTAAIYRDIQSGSRY
** : *: : : :*:*.*.* .: .*:.**.: ::*: .* :
Rv2339|M.tuberculosis_H37Rv DILIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQ
Mb2367|M.bovis_AF2122/97 DILIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQ
Mflv_3435|M.gilvum_PYR-GCK DLLIAGIAALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQ
Mvan_3189|M.vanbaalenii_PYR-1 DLLIAGISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQ
TH_3260|M.thermoresistible__bu DLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQ
MUL_0757|M.ulcerans_Agy99 DLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQ
MAV_2510|M.avium_104 DLLIAGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQ
MSMEG_3496|M.smegmatis_MC2_155 DLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQ
MLBr_02378|M.leprae_Br4923 DLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQ
MMAR_0775|M.marinum_M DLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQ
MAB_4746|M.abscessus_ATCC_1997 DLLIVGIAAVTLIFAVMMIITRAFVASLAIVGTVLLSLGAAFGISVLVWQ
*::*..:::: *:: :*:::*:..:*: .***** :**.::**:***.**
Rv2339|M.tuberculosis_H37Rv HFVGLQVHWTIVAMSVIVLLAVGSDYNLLLVSRFKEEVGAGLKTGIIRAM
Mb2367|M.bovis_AF2122/97 HFVGLQVH------------------------------------------
Mflv_3435|M.gilvum_PYR-GCK HILGQPLHWMVLAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAM
Mvan_3189|M.vanbaalenii_PYR-1 HILGTELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAM
TH_3260|M.thermoresistible__bu YIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAM
MUL_0757|M.ulcerans_Agy99 HVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAM
MAV_2510|M.avium_104 HLIGIELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSM
MSMEG_3496|M.smegmatis_MC2_155 HIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSM
MLBr_02378|M.leprae_Br4923 HILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSM
MMAR_0775|M.marinum_M DIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAM
MAB_4746|M.abscessus_ATCC_1997 HIFGLELNWIAPVFGLIILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSM
..* ::
Rv2339|M.tuberculosis_H37Rv AGTGAVVTSAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLFDTLVVRSF
Mb2367|M.bovis_AF2122/97 --------------------------------------------------
Mflv_3435|M.gilvum_PYR-GCK GGSGSVVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAF
Mvan_3189|M.vanbaalenii_PYR-1 GGSGSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAF
TH_3260|M.thermoresistible__bu GGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSF
MUL_0757|M.ulcerans_Agy99 GGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSF
MAV_2510|M.avium_104 GGTGSVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSL
MSMEG_3496|M.smegmatis_MC2_155 GGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSF
MLBr_02378|M.leprae_Br4923 GGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSF
MMAR_0775|M.marinum_M AGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSF
MAB_4746|M.abscessus_ATCC_1997 GGTGGVVTSAGLVFAFTMMSMVASDLSSIGQAGSTIGLGLLFDTLIVRSL
Rv2339|M.tuberculosis_H37Rv MTPSIAALLGRWFWWPNMIHSRPTVPEAHTRQGAR---------------
Mb2367|M.bovis_AF2122/97 --------------------------------------------------
Mflv_3435|M.gilvum_PYR-GCK MTPSIAALLGPWFWWPQRVRTRPVPAPWPRSGGLQ---------------
Mvan_3189|M.vanbaalenii_PYR-1 MTPSIAALLGPWFWWPQRVRTRPVPAPWPRPGGLQ---------------
TH_3260|M.thermoresistible__bu MMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRG---------------
MUL_0757|M.ulcerans_Agy99 MTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTP---------------
MAV_2510|M.avium_104 MTPSIAALLGKWFWWPQRVRQRPVPSPWPKPAAQE---------------
MSMEG_3496|M.smegmatis_MC2_155 MTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRD---------------
MLBr_02378|M.leprae_Br4923 MMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG---------LP-------
MMAR_0775|M.marinum_M MTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSAD
MAB_4746|M.abscessus_ATCC_1997 MTPSLAGLLGPWFWWPLRVRTGPTAEARPNGRRPYT--------------
Rv2339|M.tuberculosis_H37Rv -----RIQPHLHRG-----
Mb2367|M.bovis_AF2122/97 -------------------
Mflv_3435|M.gilvum_PYR-GCK ------SDPSEGVRA----
Mvan_3189|M.vanbaalenii_PYR-1 ------SDPSEGVKV----
TH_3260|M.thermoresistible__bu ------PATTDRVSV----
MUL_0757|M.ulcerans_Agy99 ------PPATTSV------
MAV_2510|M.avium_104 ------REVLADA------
MSMEG_3496|M.smegmatis_MC2_155 ------PEDALNRV-----
MLBr_02378|M.leprae_Br4923 ------PDRSLVYSD----
MMAR_0775|M.marinum_M GPEDTNTERLAVSSPHY--
MAB_4746|M.abscessus_ATCC_1997 ------QEGILNIATGPER