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VTVKCANDLDTHTKPPFVARMIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQ KMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADKHVQSVQDFWGDPLTAPGAQSNDGKAA YVQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILV TLLLVYRSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQE ARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAV LTVGSRFGLFEPKRLIKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPAN QGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSIP FQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLR DEIANFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQF PPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSF LSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVI AGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVGS DYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDT LIVRSFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02378 | - | - | 100% (959) | hypothetical protein MLBr_02378 |
| M. leprae Br4923 | MLBr_01231 | mmpL10 | e-115 | 29.67% (974) | hypothetical protein MLBr_01231 |
| M. leprae Br4923 | MLBr_00137 | mmpL7 | 5e-60 | 23.70% (924) | hypothetical protein MLBr_00137 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 78.83% (954) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 63.71% (926) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 78.83% (954) | transmembrane transport protein MmpL4 |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 62.92% (952) | putative membrane protein, mmpL |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 80.67% (962) | transmembrane transport protein MmpL5_2 |
| M. avium 104 | MAV_2510 | - | 0.0 | 63.24% (925) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 62.62% (931) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 59.77% (947) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 63.01% (930) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 63.38% (942) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 MSTKFANDSNTN------ARPEKPFIARMIHAFAVPIILGWLAVCVVVTV
Rv0450c|M.tuberculosis_H37Rv MSTKFANDSNTN------ARPEKPFIARMIHAFAVPIILGWLAVCVVVTV
MMAR_0771|M.marinum_M MTVKYANDPDTR------THTEKPFLARMIHAFAVPIILAWVAVCVALSV
MLBr_02378|M.leprae_Br4923 MTVKCANDLDTH------TKP--PFVARMIHRFAVPIILVWLAIAVTVSV
Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAA--HGPHRSFIPRMIRLFAVPIILGWIALIVVVNV
Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAA--RQPHRPFIPRMIRLFAVPIILGWIALIVILNV
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPA--EHPPRPFIPRMIRTFAVPLILGWVLLIAVLNS
MAV_2510|M.avium_104 MSTTFDDTRTDAIPVV--KEPVREKIPRFIRAFAVPIIIGWIALIAVLNV
MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAIIAVLNT
MAB_2301|M.abscessus_ATCC_1997 MSGSHAGR----------SAAEPTFLAKWIRRLSIPIVIGWLAIVFALNT
TH_3056|M.thermoresistible__bu MSVLDRVG----------VEPRRPRVASFIRRYSVLIILGWVALTVLATV
*: . :. *: :: ::: *: : .
Mb0458c|M.bovis_AF2122/97 FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN
Rv0450c|M.tuberculosis_H37Rv FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN
MMAR_0771|M.marinum_M FIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGK
MLBr_02378|M.leprae_Br4923 FIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD
Mflv_3435|M.gilvum_PYR-GCK TVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIVFEGD
Mvan_3189|M.vanbaalenii_PYR-1 TVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIVFEGD
MUL_0757|M.ulcerans_Agy99 VVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ
MAV_2510|M.avium_104 VVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIVLEGQ
MSMEG_3496|M.smegmatis_MC2_155 VVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMIVLEGE
MAB_2301|M.abscessus_ATCC_1997 FVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIVLEGQ
TH_3056|M.thermoresistible__bu AVPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ
:* *: * . :::.: * * : : ::* * * .*:* ::::**.
Mb0458c|M.bovis_AF2122/97 QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
Rv0450c|M.tuberculosis_H37Rv QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
MMAR_0771|M.marinum_M DALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAY
MLBr_02378|M.leprae_Br4923 KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAY
Mflv_3435|M.gilvum_PYR-GCK QPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDGKAAY
Mvan_3189|M.vanbaalenii_PYR-1 QPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDGKAAY
MUL_0757|M.ulcerans_Agy99 EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY
MAV_2510|M.avium_104 QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSNDGKASY
MSMEG_3496|M.smegmatis_MC2_155 QPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQSPDGLASY
MAB_2301|M.abscessus_ATCC_1997 ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQSTDGKATY
TH_3056|M.thermoresistible__bu EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF
. ** :* :** :: :*. . :*: ::*:*.**** . ** ** *::
Mb0458c|M.bovis_AF2122/97 VQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIKAYVTGP
Rv0450c|M.tuberculosis_H37Rv VQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIKAYVTGP
MMAR_0771|M.marinum_M VQLNLAGNQGEPLANESVEAVRKIVKETPA---------PPGVTTYVTGA
MLBr_02378|M.leprae_Br4923 VQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGITAWVTGA
Mflv_3435|M.gilvum_PYR-GCK VQVKLSGNQGEALANESVKAVQQTVSSLEP---------PPGVRAFVTGP
Mvan_3189|M.vanbaalenii_PYR-1 VQVKLAGNQGESLANESVQAAQEIVRSLEP---------PPGVRAFVTGP
MUL_0757|M.ulcerans_Agy99 VQVKLAGNQGESLANESVEAVKTIVDSLQA---------PPGVKVYVTGS
MAV_2510|M.avium_104 VQVYLAGNQGEALANESVESVQNIVKSVQA---------PNGVKAYVTGP
MSMEG_3496|M.smegmatis_MC2_155 VQVYTRGNQGEALANESVEAVQDIVESVPA---------PPGVKAYVTGP
MAB_2301|M.abscessus_ATCC_1997 VQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLTVYVTGP
TH_3056|M.thermoresistible__bu VQVNLVGRFGQAKVNEAVRAVQEIVERTPA---------PEGVETFVTGP
**: *. * :*: :.: * . * *: .:***.
Mb0458c|M.bovis_AF2122/97 SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE
Rv0450c|M.tuberculosis_H37Rv SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE
MMAR_0771|M.marinum_M AALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVE
MLBr_02378|M.leprae_Br4923 SALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIE
Mflv_3435|M.gilvum_PYR-GCK AALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMS
Mvan_3189|M.vanbaalenii_PYR-1 AALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLS
MUL_0757|M.ulcerans_Agy99 AALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLG
MAV_2510|M.avium_104 AALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLE
MSMEG_3496|M.smegmatis_MC2_155 AALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLS
MAB_2301|M.abscessus_ATCC_1997 GALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVFMLVGIQ
TH_3056|M.thermoresistible__bu AALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVE
.** :* :. :: * :. **. **:.:**..*. : : * :
Mb0458c|M.bovis_AF2122/97 LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR
Rv0450c|M.tuberculosis_H37Rv LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR
MMAR_0771|M.marinum_M LTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEAR
MLBr_02378|M.leprae_Br4923 SAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEAR
Mflv_3435|M.gilvum_PYR-GCK LATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR
Mvan_3189|M.vanbaalenii_PYR-1 LATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEAR
MUL_0757|M.ulcerans_Agy99 LLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR
MAV_2510|M.avium_104 LSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR
MSMEG_3496|M.smegmatis_MC2_155 LSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIGRYQEAR
MAB_2301|M.abscessus_ATCC_1997 LSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIGRYQEAR
TH_3056|M.thermoresistible__bu LQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAR
.:** :* ** :**: :...**. :.***.***.**: *******
Mb0458c|M.bovis_AF2122/97 QAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPC
Rv0450c|M.tuberculosis_H37Rv QAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPC
MMAR_0771|M.marinum_M QAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPC
MLBr_02378|M.leprae_Br4923 QANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPC
Mflv_3435|M.gilvum_PYR-GCK TAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPL
Mvan_3189|M.vanbaalenii_PYR-1 TNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPL
MUL_0757|M.ulcerans_Agy99 GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL
MAV_2510|M.avium_104 AVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPL
MSMEG_3496|M.smegmatis_MC2_155 SVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPL
MAB_2301|M.abscessus_ATCC_1997 AMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQTLGVPC
TH_3056|M.thermoresistible__bu EAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPG
. .:: ::: : .. :*: .**:**:** ** *:.:*:*:.:*:*
Mb0458c|M.bovis_AF2122/97 AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW
Rv0450c|M.tuberculosis_H37Rv AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW
MMAR_0771|M.marinum_M AVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRW
MLBr_02378|M.leprae_Br4923 AVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRW
Mflv_3435|M.gilvum_PYR-GCK AIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRW
Mvan_3189|M.vanbaalenii_PYR-1 AIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRW
MUL_0757|M.ulcerans_Agy99 AIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRW
MAV_2510|M.avium_104 AIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRW
MSMEG_3496|M.smegmatis_MC2_155 AIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRW
MAB_2301|M.abscessus_ATCC_1997 SVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIGTTIVRW
TH_3056|M.thermoresistible__bu AVGLLVAVAVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRW
::*: : * ..: : * : : :** ::*:* : **::*:.:***
Mb0458c|M.bovis_AF2122/97 PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS
Rv0450c|M.tuberculosis_H37Rv PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS
MMAR_0771|M.marinum_M PLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFS
MLBr_02378|M.leprae_Br4923 PLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFP
Mflv_3435|M.gilvum_PYR-GCK PGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFD
Mvan_3189|M.vanbaalenii_PYR-1 PGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFD
MUL_0757|M.ulcerans_Agy99 PGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFS
MAV_2510|M.avium_104 PGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFS
MSMEG_3496|M.smegmatis_MC2_155 PAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYAAADRHFS
MAB_2301|M.abscessus_ATCC_1997 PGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQAADRHFS
TH_3056|M.thermoresistible__bu PVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFP
* *:* : .::::** :****...*.*: ::* :**. *: .* .**
Mb0458c|M.bovis_AF2122/97 QARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE
Rv0450c|M.tuberculosis_H37Rv QARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE
MMAR_0771|M.marinum_M QARMK-PDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPD
MLBr_02378|M.leprae_Br4923 QARMK-PEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPD
Mflv_3435|M.gilvum_PYR-GCK QARMN-PELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPD
Mvan_3189|M.vanbaalenii_PYR-1 QARMN-PELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPD
MUL_0757|M.ulcerans_Agy99 QARMN-PEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPD
MAV_2510|M.avium_104 QARMN-PEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQ
MSMEG_3496|M.smegmatis_MC2_155 QARMN-PELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQ
MAB_2301|M.abscessus_ATCC_1997 QARMN-PEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQAITRPQ
TH_3056|M.thermoresistible__bu ASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPE
: *. *:::::::*:*:**.:*:*:::::*: :* * *:..**::***:
Mb0458c|M.bovis_AF2122/97 GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR
Rv0450c|M.tuberculosis_H37Rv GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR
MMAR_0771|M.marinum_M GTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRR
MLBr_02378|M.leprae_Br4923 GTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRR
Mflv_3435|M.gilvum_PYR-GCK GKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEK
Mvan_3189|M.vanbaalenii_PYR-1 GKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEK
MUL_0757|M.ulcerans_Agy99 GKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMER
MAV_2510|M.avium_104 GTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEK
MSMEG_3496|M.smegmatis_MC2_155 GTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEE
MAB_2301|M.abscessus_ATCC_1997 GTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENVVIMKR
TH_3056|M.thermoresistible__bu GRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRR
* :.*::*** :**. . * : .: .: : .: : .
Mb0458c|M.bovis_AF2122/97 MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE
Rv0450c|M.tuberculosis_H37Rv MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE
MMAR_0771|M.marinum_M MYGLMTQLANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWE
MLBr_02378|M.leprae_Br4923 MHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWE
Mflv_3435|M.gilvum_PYR-GCK MSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWE
Mvan_3189|M.vanbaalenii_PYR-1 MSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWE
MUL_0757|M.ulcerans_Agy99 MHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWE
MAV_2510|M.avium_104 MQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWE
MSMEG_3496|M.smegmatis_MC2_155 MLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIRNYFYWE
MAB_2301|M.abscessus_ATCC_1997 TLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRNYLYWE
TH_3056|M.thermoresistible__bu MQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWE
: * :: : .:*: :::*:*: **:*.*::**
Mb0458c|M.bovis_AF2122/97 KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI
Rv0450c|M.tuberculosis_H37Rv KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI
MMAR_0771|M.marinum_M KHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETF
MLBr_02378|M.leprae_Br4923 RHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQF
Mflv_3435|M.gilvum_PYR-GCK PHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALM
Mvan_3189|M.vanbaalenii_PYR-1 PHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALM
MUL_0757|M.ulcerans_Agy99 KHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMM
MAV_2510|M.avium_104 KHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALM
MSMEG_3496|M.smegmatis_MC2_155 PHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIM
MAB_2301|M.abscessus_ATCC_1997 KHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPKMVSDM
TH_3056|M.thermoresistible__bu PHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQF
** .**:* ::**:**:** :: : : : :: : .:* ***:* :
Mb0458c|M.bovis_AF2122/97 PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS
Rv0450c|M.tuberculosis_H37Rv PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS
MMAR_0771|M.marinum_M PPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDS
MLBr_02378|M.leprae_Br4923 PPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDS
Mflv_3435|M.gilvum_PYR-GCK PEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDS
Mvan_3189|M.vanbaalenii_PYR-1 PEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDS
MUL_0757|M.ulcerans_Agy99 PEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDS
MAV_2510|M.avium_104 PSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDS
MSMEG_3496|M.smegmatis_MC2_155 PPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDS
MAB_2301|M.abscessus_ATCC_1997 SAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAAKNDDS
TH_3056|M.thermoresistible__bu PQMIETMESSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDS
. * *: : :*: : * :* .: :**:*** : ****
Mb0458c|M.bovis_AF2122/97 FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI
Rv0450c|M.tuberculosis_H37Rv FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI
MMAR_0771|M.marinum_M FYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQI
MLBr_02378|M.leprae_Br4923 FYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAI
Mflv_3435|M.gilvum_PYR-GCK FYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKI
Mvan_3189|M.vanbaalenii_PYR-1 FYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKI
MUL_0757|M.ulcerans_Agy99 FYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKI
MAV_2510|M.avium_104 FYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAI
MSMEG_3496|M.smegmatis_MC2_155 FYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAI
MAB_2301|M.abscessus_ATCC_1997 FYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLSHVEPI
TH_3056|M.thermoresistible__bu FYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPI
****** :.* :*:: :: *:*.**:*.*::: : *** : *: : *
Mb0458c|M.bovis_AF2122/97 RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF
Rv0450c|M.tuberculosis_H37Rv RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF
MMAR_0771|M.marinum_M RTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIF
MLBr_02378|M.leprae_Br4923 RTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIF
Mflv_3435|M.gilvum_PYR-GCK KTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIF
Mvan_3189|M.vanbaalenii_PYR-1 KTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIF
MUL_0757|M.ulcerans_Agy99 KTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIF
MAV_2510|M.avium_104 KKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIF
MSMEG_3496|M.smegmatis_MC2_155 KQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIAALCLIF
MAB_2301|M.abscessus_ATCC_1997 KQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISALCLIF
TH_3056|M.thermoresistible__bu YIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIF
** *::******.: * :.*:.: :*: :* :**:**.*::: ***
Mb0458c|M.bovis_AF2122/97 IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM
Rv0450c|M.tuberculosis_H37Rv IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM
MMAR_0771|M.marinum_M IIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAM
MLBr_02378|M.leprae_Br4923 IIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAM
Mflv_3435|M.gilvum_PYR-GCK IIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAM
Mvan_3189|M.vanbaalenii_PYR-1 IIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAM
MUL_0757|M.ulcerans_Agy99 IIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAM
MAV_2510|M.avium_104 IIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAM
MSMEG_3496|M.smegmatis_MC2_155 IIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAM
MAB_2301|M.abscessus_ATCC_1997 LIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHWLVMQM
TH_3056|M.thermoresistible__bu MIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAM
:**:::**..:*: ****** :**.****:**::**::: **::*: *
Mb0458c|M.bovis_AF2122/97 SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF
Rv0450c|M.tuberculosis_H37Rv SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF
MMAR_0771|M.marinum_M SVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVF
MLBr_02378|M.leprae_Br4923 SVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVF
Mflv_3435|M.gilvum_PYR-GCK AVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVF
Mvan_3189|M.vanbaalenii_PYR-1 AVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVF
MUL_0757|M.ulcerans_Agy99 AVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVF
MAV_2510|M.avium_104 SVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVF
MSMEG_3496|M.smegmatis_MC2_155 AVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVF
MAB_2301|M.abscessus_ATCC_1997 AIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTSAGLVF
TH_3056|M.thermoresistible__bu SVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVF
::*:*****:****:**:*:*:*: .*: *****:***:* *** *****
Mb0458c|M.bovis_AF2122/97 AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW
Rv0450c|M.tuberculosis_H37Rv AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW
MMAR_0771|M.marinum_M AFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFW
MLBr_02378|M.leprae_Br4923 AFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFW
Mflv_3435|M.gilvum_PYR-GCK ALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFW
Mvan_3189|M.vanbaalenii_PYR-1 ALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFW
MUL_0757|M.ulcerans_Agy99 AFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFW
MAV_2510|M.avium_104 AFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFW
MSMEG_3496|M.smegmatis_MC2_155 AFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFW
MAB_2301|M.abscessus_ATCC_1997 AFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLLGRWFW
TH_3056|M.thermoresistible__bu AATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFW
* ** : **:* ::.******.:******:::*::* *::*:::* ***
Mb0458c|M.bovis_AF2122/97 WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------
Rv0450c|M.tuberculosis_H37Rv WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------
MMAR_0771|M.marinum_M WPMRVRTRPARTPSSPTADPEPDRALAMSGER--------------
MLBr_02378|M.leprae_Br4923 WPQQGRTRPLLTVAAPVG-LPPDRSLVYSD----------------
Mflv_3435|M.gilvum_PYR-GCK WPQRVRTRPVPAPWPRSGGLQSDPSEGVRA----------------
Mvan_3189|M.vanbaalenii_PYR-1 WPQRVRTRPVPAPWPRPGGLQSDPSEGVKV----------------
MUL_0757|M.ulcerans_Agy99 WPQVVRQRPAPQPWPTPAPTPPPATTSV------------------
MAV_2510|M.avium_104 WPQRVRQRPVPSPWPKPAAQEREVLADA------------------
MSMEG_3496|M.smegmatis_MC2_155 WPQRVRQRPLPAPWPQPVQRDPEDALNRV-----------------
MAB_2301|M.abscessus_ATCC_1997 WPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPSV
TH_3056|M.thermoresistible__bu WPQRVRTRPASAMLRPVGPRPLVRSLLLRD----------------
** * **