For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSNPSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDD APSVIAMKRVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASG AQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVPAPPGVKAYVTGPAALSADQHVASDRSVRVIE ALTFAVIITMLLLVYRSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYA IFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLAIGMSVVVL ASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDR RYLPQDLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQ GTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMH GMVEDIKELRDHIADFDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLD ELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDSFYLPPETFEN PDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDL QEGANYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAM AVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGT TIGLGLLFDTLVIRSFMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3496 | - | - | 100% (969) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_0225 | - | 0.0 | 83.45% (967) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_4383 | - | 0.0 | 72.04% (937) | MmpL5 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0695c | mmpL5 | 0.0 | 71.58% (950) | transmembrane transport protein MmpL5 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 73.76% (968) | transport protein |
M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 71.47% (950) | transmembrane transport protein MmpL5 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 62.62% (931) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4382c | - | 0.0 | 63.98% (966) | putative membrane protein, MmpL |
M. marinum M | MMAR_1005 | mmpL5 | 0.0 | 70.95% (957) | transmembrane transport protein, MmpL5 |
M. avium 104 | MAV_2510 | - | 0.0 | 75.18% (963) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 67.98% (968) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 70.48% (962) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 74.59% (968) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARPG------GIAKWIRVLAVPIILVWVAI MAV_2510|M.avium_104 MSTTFDDTRTDAIPVV--KEPVRE------KIPRFIRAFAVPIIIGWIAL Mb0695c|M.bovis_AF2122/97 MIVQRTAAPTGSVPPD--RHAARP------FIPRMIRTFAVPIILGWLVT Rv0676c|M.tuberculosis_H37Rv MIVQRTAAPTGSVPPD--RHAARP------FIPRMIRTFAVPIILGWLVT MMAR_1005|M.marinum_M MTATTTDTPTDVVPPA--EHPPRP------FIPRMIRTFAVPLILGWVLL MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPA--EHPPRP------FIPRMIRTFAVPLILGWVLL Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAA--HGPHRS------FIPRMIRLFAVPIILGWIAL Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAA--RQPHRP------FIPRMIRLFAVPIILGWIAL TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTD--RLDIKVSTHGPSFISTWIRRLSLPIIVGWIAL MAB_4382c|M.abscessus_ATCC_199 MSKPMNDPTTDAFPAA--RHAARP------WLPRMIRVLAVPIVLGWIAV MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKPP--------------FVARMIHRFAVPIILVWLAI * :. *: :::*::: *: MSMEG_3496|M.smegmatis_MC2_155 IAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVM MAV_2510|M.avium_104 IAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVM Mb0695c|M.bovis_AF2122/97 IAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAM Rv0676c|M.tuberculosis_H37Rv IAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAM MMAR_1005|M.marinum_M IAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAM MUL_0757|M.ulcerans_Agy99 IAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAM Mflv_3435|M.gilvum_PYR-GCK IVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVM Mvan_3189|M.vanbaalenii_PYR-1 IVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVM TH_3260|M.thermoresistible__bu IALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVM MAB_4382c|M.abscessus_ATCC_199 TIALNTVVPQLEEVGHMRAVSMSPNDAPAMIATKRVGEVFEEFKTSSSVM MLBr_02378|M.leprae_Br4923 AVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIM :. :*.*: **. ::*.::*. * : :: :::* :* * .:.* * MSMEG_3496|M.smegmatis_MC2_155 IVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQSP MAV_2510|M.avium_104 IVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSN Mb0695c|M.bovis_AF2122/97 IVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSS Rv0676c|M.tuberculosis_H37Rv IVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSS MMAR_1005|M.marinum_M IVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSG MUL_0757|M.ulcerans_Agy99 IVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSG Mflv_3435|M.gilvum_PYR-GCK IVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSN Mvan_3189|M.vanbaalenii_PYR-1 IVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSN TH_3260|M.thermoresistible__bu IVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSP MAB_4382c|M.abscessus_ATCC_199 IVLEGEQSLGADAHRFYDQMVRDLRADTTHVQHVQDFWADALTAAAAQSS MLBr_02378|M.leprae_Br4923 IVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSN **:**:..** *: :** :: *.** **: :**:*.*.**... ** MSMEG_3496|M.smegmatis_MC2_155 DGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---APPGVKAYVTGP MAV_2510|M.avium_104 DGKASYVQVYLAGNQGEALANESVESVQNIVKSVQ---APNGVKAYVTGP Mb0695c|M.bovis_AF2122/97 DGKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGS Rv0676c|M.tuberculosis_H37Rv DGKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGS MMAR_1005|M.marinum_M DGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGS MUL_0757|M.ulcerans_Agy99 DGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGS Mflv_3435|M.gilvum_PYR-GCK DGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGVRAFVTGP Mvan_3189|M.vanbaalenii_PYR-1 DGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGVRAFVTGP TH_3260|M.thermoresistible__bu DGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTGG MAB_4382c|M.abscessus_ATCC_199 DGKAAYVQVYIAGDQGEALANESVEAVRHITAAVP---PSPGVRVYVTGP MLBr_02378|M.leprae_Br4923 DGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGITAWVTGA ** ::***: *:*** **:**:.:.: .. *: .:*** MSMEG_3496|M.smegmatis_MC2_155 AALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLS MAV_2510|M.avium_104 AALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLE Mb0695c|M.bovis_AF2122/97 AALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLG Rv0676c|M.tuberculosis_H37Rv AALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLG MMAR_1005|M.marinum_M AALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLG MUL_0757|M.ulcerans_Agy99 AALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLG Mflv_3435|M.gilvum_PYR-GCK AALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMS Mvan_3189|M.vanbaalenii_PYR-1 AALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLS TH_3260|M.thermoresistible__bu AAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLIG MAB_4382c|M.abscessus_ATCC_199 ATTSADQEIVANDSMELIELVTFGVIMVMLLLVYRSVITMVIVVAMVMLE MLBr_02378|M.leprae_Br4923 SALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIE :: ** . .: *: * :. ** **:****.:* : : * : MSMEG_3496|M.smegmatis_MC2_155 LSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIGRYQEAR MAV_2510|M.avium_104 LSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR Mb0695c|M.bovis_AF2122/97 LLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR Rv0676c|M.tuberculosis_H37Rv LLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR MMAR_1005|M.marinum_M LLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR MUL_0757|M.ulcerans_Agy99 LLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR Mflv_3435|M.gilvum_PYR-GCK LATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR Mvan_3189|M.vanbaalenii_PYR-1 LATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEAR TH_3260|M.thermoresistible__bu LLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEAR MAB_4382c|M.abscessus_ATCC_199 LASARGLVALLSYHNAFGLTSFATSLVVTLAIAAATDYAIFLIGRYQEAR MLBr_02378|M.leprae_Br4923 SAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEAR :** :*:*. :**: **..*:. **** ..**.**: ******* MSMEG_3496|M.smegmatis_MC2_155 SVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPL MAV_2510|M.avium_104 AVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPL Mb0695c|M.bovis_AF2122/97 GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL Rv0676c|M.tuberculosis_H37Rv GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL MMAR_1005|M.marinum_M GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL MUL_0757|M.ulcerans_Agy99 GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL Mflv_3435|M.gilvum_PYR-GCK TAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPL Mvan_3189|M.vanbaalenii_PYR-1 TNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPL TH_3260|M.thermoresistible__bu SVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSLGPPL MAB_4382c|M.abscessus_ATCC_199 RAGEDRESAYYTMFHGTAHVVLASGLTIAGATFCLHFTRLPYFKTTGIPL MLBr_02378|M.leprae_Br4923 QANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPC . .: :::**: .* **: .**:**:*** ** *:.:***:: * * MSMEG_3496|M.smegmatis_MC2_155 AIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRW MAV_2510|M.avium_104 AIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRW Mb0695c|M.bovis_AF2122/97 AIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRW Rv0676c|M.tuberculosis_H37Rv AIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRW MMAR_1005|M.marinum_M AIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRW MUL_0757|M.ulcerans_Agy99 AIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRW Mflv_3435|M.gilvum_PYR-GCK AIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRW Mvan_3189|M.vanbaalenii_PYR-1 AIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRW TH_3260|M.thermoresistible__bu AIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGASVVRW MAB_4382c|M.abscessus_ATCC_199 SIGMAIVVAMALTLGPALISVASRFGNVLEPKGAGKARGWRRVGAATVRW MLBr_02378|M.leprae_Br4923 AVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRW ::** : : .: : * ::* :** :**: : * **::*: *** MSMEG_3496|M.smegmatis_MC2_155 PAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYAAADRHFS MAV_2510|M.avium_104 PGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFS Mb0695c|M.bovis_AF2122/97 PGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFS Rv0676c|M.tuberculosis_H37Rv PGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFS MMAR_1005|M.marinum_M PGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFS MUL_0757|M.ulcerans_Agy99 PGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFS Mflv_3435|M.gilvum_PYR-GCK PGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFD Mvan_3189|M.vanbaalenii_PYR-1 PGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFD TH_3260|M.thermoresistible__bu PGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAERHFD MAB_4382c|M.abscessus_ATCC_199 PGAILVAAVTMALVGLLTLPGYHTTYNDRIYLPGQVPANVGYAAADRHFS MLBr_02378|M.leprae_Br4923 PLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFP * .*:: : :::****:****:*.*:** *** ..*:* *: .*:.** MSMEG_3496|M.smegmatis_MC2_155 QARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQG MAV_2510|M.avium_104 QARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQG Mb0695c|M.bovis_AF2122/97 QARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDG Rv0676c|M.tuberculosis_H37Rv QARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDG MMAR_1005|M.marinum_M QARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDG MUL_0757|M.ulcerans_Agy99 QARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDG Mflv_3435|M.gilvum_PYR-GCK QARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDG Mvan_3189|M.vanbaalenii_PYR-1 QARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDG TH_3260|M.thermoresistible__bu PARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGITRPEG MAB_4382c|M.abscessus_ATCC_199 KAKMNPDLLLVESDHDLRNPADFLVIDKIAKALARVRGIAQVQTITRPDG MLBr_02378|M.leprae_Br4923 QARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDG *:::*::*::*****:**.:***:::::*: : * **.:** ****:* MSMEG_3496|M.smegmatis_MC2_155 TPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEEM MAV_2510|M.avium_104 TPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEKM Mb0695c|M.bovis_AF2122/97 KPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERM Rv0676c|M.tuberculosis_H37Rv KPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERM MMAR_1005|M.marinum_M KPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERM MUL_0757|M.ulcerans_Agy99 KPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERM Mflv_3435|M.gilvum_PYR-GCK KPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKM Mvan_3189|M.vanbaalenii_PYR-1 KPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKM TH_3260|M.thermoresistible__bu TPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDTMDKM MAB_4382c|M.abscessus_ATCC_199 KPIKHTSIPFNMSTANTAQTLTNDYSQANFANLLKQADAMQVTIDSMEKM MLBr_02378|M.leprae_Br4923 TAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRM ..:.*:**** :* .. * . .* : :* .: : : * .* MSMEG_3496|M.smegmatis_MC2_155 LKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIRNYFYWEP MAV_2510|M.avium_104 QSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWEK Mb0695c|M.bovis_AF2122/97 HSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEK Rv0676c|M.tuberculosis_H37Rv HSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEK MMAR_1005|M.marinum_M HDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEK MUL_0757|M.ulcerans_Agy99 HDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEK Mflv_3435|M.gilvum_PYR-GCK SGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEP Mvan_3189|M.vanbaalenii_PYR-1 SNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEP TH_3260|M.thermoresistible__bu IALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYFYWEP MAB_4382c|M.abscessus_ATCC_199 QAITQQMAEVTASMSANMKNTAQDINQLRDNMSNFDDQFRPIRNYFYWEK MLBr_02378|M.leprae_Br4923 HQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWER : : : : . .:*: :::*:* **:*.***** MSMEG_3496|M.smegmatis_MC2_155 HCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIMP MAV_2510|M.avium_104 HCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALMP Mb0695c|M.bovis_AF2122/97 HCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMP Rv0676c|M.tuberculosis_H37Rv HCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMP MMAR_1005|M.marinum_M HCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMP MUL_0757|M.ulcerans_Agy99 HCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMP Mflv_3435|M.gilvum_PYR-GCK HCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMP Mvan_3189|M.vanbaalenii_PYR-1 HCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMP TH_3260|M.thermoresistible__bu HCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQMLTLLP MAB_4382c|M.abscessus_ATCC_199 HCFDIPMCWALRSVFDALDGISLMSDDFDTLVPDIQRMAGLMPQMVVLMP MLBr_02378|M.leprae_Br4923 HCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFP ** .**:* ::**:**:***:. : : : :: :..: ****: :* MSMEG_3496|M.smegmatis_MC2_155 PMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDSF MAV_2510|M.avium_104 SMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDSF Mb0695c|M.bovis_AF2122/97 EMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSF Rv0676c|M.tuberculosis_H37Rv EMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSF MMAR_1005|M.marinum_M EMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSF MUL_0757|M.ulcerans_Agy99 EMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSF Mflv_3435|M.gilvum_PYR-GCK EMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSF Mvan_3189|M.vanbaalenii_PYR-1 EMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSF TH_3260|M.thermoresistible__bu TTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARNDDSF MAB_4382c|M.abscessus_ATCC_199 PMIASMKEQKQIMLSQYQVQKAQQDQTMAMQANASAMGQAFDDAKNDDSF MLBr_02378|M.leprae_Br4923 PMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSF : .*: : :*: . ** : :**:*** : ***** MSMEG_3496|M.smegmatis_MC2_155 YLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAIK MAV_2510|M.avium_104 YLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAIK Mb0695c|M.bovis_AF2122/97 YLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIK Rv0676c|M.tuberculosis_H37Rv YLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIK MMAR_1005|M.marinum_M YLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIK MUL_0757|M.ulcerans_Agy99 YLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIK Mflv_3435|M.gilvum_PYR-GCK YLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIK Mvan_3189|M.vanbaalenii_PYR-1 YLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIK TH_3260|M.thermoresistible__bu YLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKIEPIK MAB_4382c|M.abscessus_ATCC_199 YLPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQSDPLTEEGTSRVEPLK MLBr_02378|M.leprae_Br4923 YLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIR ***** *.. :*: .:: *:*.:***.** * * .** : * : :: MSMEG_3496|M.smegmatis_MC2_155 QAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIAALCLIFI MAV_2510|M.avium_104 KAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIFI Mb0695c|M.bovis_AF2122/97 TAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFI Rv0676c|M.tuberculosis_H37Rv TAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFI MMAR_1005|M.marinum_M TAAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMIAGISALCLIFI MUL_0757|M.ulcerans_Agy99 TAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFI Mflv_3435|M.gilvum_PYR-GCK TAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIFI Mvan_3189|M.vanbaalenii_PYR-1 TAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFI TH_3260|M.thermoresistible__bu KAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVCLIFI MAB_4382c|M.abscessus_ATCC_199 TAAEDAIKGTPLEGSSIYVGGSAALYKDMQEGADYDLLIAAVAALILIFL MLBr_02378|M.leprae_Br4923 TAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFI ** :*:******.: :*:.*:.: :**:.:* :**:**.:::: ***: MSMEG_3496|M.smegmatis_MC2_155 IMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAMA MAV_2510|M.avium_104 IMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAMS Mb0695c|M.bovis_AF2122/97 IMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMA Rv0676c|M.tuberculosis_H37Rv IMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMA MMAR_1005|M.marinum_M IMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMA MUL_0757|M.ulcerans_Agy99 IMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMA Mflv_3435|M.gilvum_PYR-GCK IMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAMA Mvan_3189|M.vanbaalenii_PYR-1 IMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMA TH_3260|M.thermoresistible__bu IMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMVFPMA MAB_4382c|M.abscessus_ATCC_199 IMVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLWQHIIGTPLHWMVLPMA MLBr_02378|M.leprae_Br4923 IMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMS **:: **..**:******* :**.****:***:**:::* :*::*:.*: MSMEG_3496|M.smegmatis_MC2_155 VIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFA MAV_2510|M.avium_104 VIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFA Mb0695c|M.bovis_AF2122/97 VIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFA Rv0676c|M.tuberculosis_H37Rv VIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFA MMAR_1005|M.marinum_M VIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFA MUL_0757|M.ulcerans_Agy99 VIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFA Mflv_3435|M.gilvum_PYR-GCK VIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFA Mvan_3189|M.vanbaalenii_PYR-1 VIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFA TH_3260|M.thermoresistible__bu LIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAGLVFG MAB_4382c|M.abscessus_ATCC_199 VIILLAVGADYNLLLVSRMKEELHAGLHTGTIRSMAGTGSVVTSAGLVFA MLBr_02378|M.leprae_Br4923 VIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFA :*:*****:*****:*:*:::*: **: ** **:*.*:*.*** *****. MSMEG_3496|M.smegmatis_MC2_155 FTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFWW MAV_2510|M.avium_104 FTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFWW Mb0695c|M.bovis_AF2122/97 FTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWW Rv0676c|M.tuberculosis_H37Rv FTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWW MMAR_1005|M.marinum_M FTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWW MUL_0757|M.ulcerans_Agy99 FTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWW Mflv_3435|M.gilvum_PYR-GCK LTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWW Mvan_3189|M.vanbaalenii_PYR-1 LTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWW TH_3260|M.thermoresistible__bu LTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGRWFWW MAB_4382c|M.abscessus_ATCC_199 FTMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRSFMTPSIASLLGRWFWW MLBr_02378|M.leprae_Br4923 FTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWW :** : **.: *:.*:*****:******:::*::* ****:*:* **** MSMEG_3496|M.smegmatis_MC2_155 PQRVRQRPLPAPWPQPVQRDPEDALNRV- MAV_2510|M.avium_104 PQRVRQRPVPSPWPKPAAQEREVLADA-- Mb0695c|M.bovis_AF2122/97 PQVVRQRPVPQPWPSPASARTFALV---- Rv0676c|M.tuberculosis_H37Rv PQVVRQRPIPQPWPSPASARTFALV---- MMAR_1005|M.marinum_M PQVVRQRPAPQPWPTPAPTP--ATTSV-- MUL_0757|M.ulcerans_Agy99 PQVVRQRPAPQPWPTPAPTPPPATTSV-- Mflv_3435|M.gilvum_PYR-GCK PQRVRTRPVPAPWPRSGGLQSDPSEGVRA Mvan_3189|M.vanbaalenii_PYR-1 PQRVRTRPVPAPWPRPGGLQSDPSEGVKV TH_3260|M.thermoresistible__bu PQFVRKRPVPQPWPSVPPRGPATTDRVSV MAB_4382c|M.abscessus_ATCC_199 PMVVRPRPRPQPWPQPLHAGAAEAVRA-- MLBr_02378|M.leprae_Br4923 PQQGRTRPLLTVAAPVGLPPDRSLVYSD- * * ** .