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MRHGSGDHTARPPRIARLIRTLSIPIILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTG KVFGEFDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPLTASGAQSADGKSAYV QVNLAGDQGTTLANESVDAVRKIIAETPGPAGVQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLML LLVYRSVITTIVALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFLLGRYHEAR HRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPLFRSMGVPCALVILVIVAAALTLAPAILA LGSRFGLFEPKRKYDEGGWRRIGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVG YAAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRVQAITRPLGTPIEHSSIPFQ IGLQGAGQIQNMKYMKDRMADMLTMANQMGILIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDL MYTFDDFFRPIRNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLMPRVLAEFPP MIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFDEAKNDDSFYLPPEVFDNPDFKRGLKMFLS PDGKAVRMTVSHQGNPASVQGIETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAG IASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDLHWFVVPLSVIILLAVGSDY NLLLIARFKEELHGGLKTGFIRAMGGSGKVVTNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLI VRSFMMPSIAALLGRWFWWPLRVRTHGTAGV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3150 | - | - | 100% (941) | MmpL family protein |
M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 59.47% (940) | putative membrane protein, mmpL |
M. abscessus ATCC 19977 | MAB_1134c | - | 0.0 | 58.34% (941) | membrane protein MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 59.38% (928) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 57.00% (921) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 59.38% (928) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 60.60% (929) | hypothetical protein MLBr_02378 |
M. marinum M | MMAR_0775 | - | 0.0 | 61.41% (933) | MmpL family transport protein |
M. avium 104 | MAV_4755 | - | 0.0 | 62.39% (920) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 59.40% (931) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 57.48% (929) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 58.53% (926) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 57.03% (924) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4418|M.gilvum_PYR-GCK ---------------------------------MADAGRSGIGRIIRVLA Mvan_1936|M.vanbaalenii_PYR-1 ---------------------------------MADAGRSGIGRIIHLLA TH_3260|M.thermoresistible__bu -----------MTANPGHVRTDEAPTDRLDIK-VSTHGPSFISTWIRRLS MUL_0757|M.ulcerans_Agy99 -----------MTAT-----TTDTPTDVVPPA-EHPPRP-FIPRMIRTFA MSMEG_3496|M.smegmatis_MC2_155 -----------MSNP-----SHDAPTDAMGVSGPKHARPGGIAKWIRVLA MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA Mb0458c|M.bovis_AF2122/97 ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA Rv0450c|M.tuberculosis_H37Rv ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA MLBr_02378|M.leprae_Br4923 ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA MAB_3150|M.abscessus_ATCC_1997 ---------------------------MRHGSGDHTARPPRIARLIRTLS MAV_4755|M.avium_104 -----------------------------------------------MLS :: Mflv_4418|M.gilvum_PYR-GCK VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF Mvan_1936|M.vanbaalenii_PYR-1 VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF TH_3260|M.thermoresistible__bu LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF MUL_0757|M.ulcerans_Agy99 VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF MSMEG_3496|M.smegmatis_MC2_155 VPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVF MMAR_0775|M.marinum_M VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF Mb0458c|M.bovis_AF2122/97 VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF Rv0450c|M.tuberculosis_H37Rv VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF MAB_3150|M.abscessus_ATCC_1997 IPIILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVF MAV_4755|M.avium_104 LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF :*: : *: : *.*: *.. ::* ::. * : :* : * * Mflv_4418|M.gilvum_PYR-GCK EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD Mvan_1936|M.vanbaalenii_PYR-1 DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD TH_3260|M.thermoresistible__bu DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD MUL_0757|M.ulcerans_Agy99 REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD MSMEG_3496|M.smegmatis_MC2_155 EEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGD MMAR_0775|M.marinum_M NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD Mb0458c|M.bovis_AF2122/97 KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD Rv0450c|M.tuberculosis_H37Rv KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD MLBr_02378|M.leprae_Br4923 NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD MAB_3150|M.abscessus_ATCC_1997 GEFDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGD MAV_4755|M.avium_104 NEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSD * ::* *:::**.. *. *: :** :: .*. * ::: : * *.* Mflv_4418|M.gilvum_PYR-GCK PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---AP Mvan_1936|M.vanbaalenii_PYR-1 PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---AP TH_3260|M.thermoresistible__bu PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP MUL_0757|M.ulcerans_Agy99 PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---QAP MSMEG_3496|M.smegmatis_MC2_155 PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---AP MMAR_0775|M.marinum_M PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP Mb0458c|M.bovis_AF2122/97 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP Rv0450c|M.tuberculosis_H37Rv PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP MAB_3150|M.abscessus_ATCC_1997 PLTASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAETP---GP MAV_4755|M.avium_104 PLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP---AP ****.* ** ** ::*** * ** : *:: :*: :: .* Mflv_4418|M.gilvum_PYR-GCK PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM Mvan_1936|M.vanbaalenii_PYR-1 PGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATM TH_3260|M.thermoresistible__bu EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV MUL_0757|M.ulcerans_Agy99 PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA MSMEG_3496|M.smegmatis_MC2_155 PGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTV MMAR_0775|M.marinum_M PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV Mb0458c|M.bovis_AF2122/97 PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV Rv0450c|M.tuberculosis_H37Rv PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV MLBr_02378|M.leprae_Br4923 PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV MAB_3150|M.abscessus_ATCC_1997 AGVQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITT MAV_4755|M.avium_104 PGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTT *: .:*:* : ** .. *: :. *: ** *:**. * Mflv_4418|M.gilvum_PYR-GCK VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI Mvan_1936|M.vanbaalenii_PYR-1 VLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAI TH_3260|M.thermoresistible__bu LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI MUL_0757|M.ulcerans_Agy99 AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI MSMEG_3496|M.smegmatis_MC2_155 ILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAI MMAR_0775|M.marinum_M ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI Mb0458c|M.bovis_AF2122/97 VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI Rv0450c|M.tuberculosis_H37Rv VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI MLBr_02378|M.leprae_Br4923 ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI MAB_3150|M.abscessus_ATCC_1997 IVALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVI MAV_4755|M.avium_104 VLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVI * : . :* * . ***: :*..::. : ** ..** * Mflv_4418|M.gilvum_PYR-GCK FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL Mvan_1936|M.vanbaalenii_PYR-1 FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL TH_3260|M.thermoresistible__bu FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL MUL_0757|M.ulcerans_Agy99 FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL MSMEG_3496|M.smegmatis_MC2_155 FLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRM MMAR_0775|M.marinum_M FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL Mb0458c|M.bovis_AF2122/97 FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM Rv0450c|M.tuberculosis_H37Rv FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM MLBr_02378|M.leprae_Br4923 FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM MAB_3150|M.abscessus_ATCC_1997 FLLGRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRL MAV_4755|M.avium_104 FLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARL * ***:*** . .: :::* : .. **:*.**:** ** ** :*: Mflv_4418|M.gilvum_PYR-GCK PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW Mvan_1936|M.vanbaalenii_PYR-1 PYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGW TH_3260|M.thermoresistible__bu PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW MUL_0757|M.ulcerans_Agy99 PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW MSMEG_3496|M.smegmatis_MC2_155 PYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGW MMAR_0775|M.marinum_M PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW Mb0458c|M.bovis_AF2122/97 PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW Rv0450c|M.tuberculosis_H37Rv PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW MLBr_02378|M.leprae_Br4923 PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW MAB_3150|M.abscessus_ATCC_1997 PLFRSMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPKRKYDEGGW MAV_4755|M.avium_104 PYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVRGW * *:::* * *: : : .:**:..*:: : : * ::*** * Mflv_4418|M.gilvum_PYR-GCK RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV Mvan_1936|M.vanbaalenii_PYR-1 RRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANV TH_3260|M.thermoresistible__bu RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA MUL_0757|M.ulcerans_Agy99 RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE MSMEG_3496|M.smegmatis_MC2_155 RKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANT MMAR_0775|M.marinum_M RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV Mb0458c|M.bovis_AF2122/97 RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ Rv0450c|M.tuberculosis_H37Rv RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ MLBr_02378|M.leprae_Br4923 RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ MAB_3150|M.abscessus_ATCC_1997 RRIGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKV MAV_4755|M.avium_104 RKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANA *::*. :**** *:: : .::::*:::* * ..*. : : * *:: Mflv_4418|M.gilvum_PYR-GCK GYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVA Mvan_1936|M.vanbaalenii_PYR-1 GYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVA TH_3260|M.thermoresistible__bu GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS MUL_0757|M.ulcerans_Agy99 GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS MSMEG_3496|M.smegmatis_MC2_155 GYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGIS MMAR_0775|M.marinum_M GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA Mb0458c|M.bovis_AF2122/97 GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS Rv0450c|M.tuberculosis_H37Rv GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS MLBr_02378|M.leprae_Br4923 GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS MAB_3150|M.abscessus_ATCC_1997 GYAAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVG MAV_4755|M.avium_104 AMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIE . .*::** **::**:*::*:***:*:.:*:*:::::*: * *: Mflv_4418|M.gilvum_PYR-GCK RVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAM Mvan_1936|M.vanbaalenii_PYR-1 RVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAM TH_3260|M.thermoresistible__bu RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM MUL_0757|M.ulcerans_Agy99 RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI MSMEG_3496|M.smegmatis_MC2_155 RVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEM MMAR_0775|M.marinum_M RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM Mb0458c|M.bovis_AF2122/97 RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM Rv0450c|M.tuberculosis_H37Rv RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM MLBr_02378|M.leprae_Br4923 RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM MAB_3150|M.abscessus_ATCC_1997 RVQAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQM MAV_4755|M.avium_104 RVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADEL *** :*** * .:.*::*** :. .: . :: .: .:* . : Mflv_4418|M.gilvum_PYR-GCK QTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFR Mvan_1936|M.vanbaalenii_PYR-1 QTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVR TH_3260|M.thermoresistible__bu QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR MUL_0757|M.ulcerans_Agy99 QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR MSMEG_3496|M.smegmatis_MC2_155 QKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLR MMAR_0775|M.marinum_M QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR Mb0458c|M.bovis_AF2122/97 ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR Rv0450c|M.tuberculosis_H37Rv ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR MLBr_02378|M.leprae_Br4923 AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR MAB_3150|M.abscessus_ATCC_1997 GILIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFR MAV_4755|M.avium_104 DKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFR : : .: : : . : .:*: : :*** * Mflv_4418|M.gilvum_PYR-GCK PVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDE Mvan_1936|M.vanbaalenii_PYR-1 PVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDA TH_3260|M.thermoresistible__bu PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND MUL_0757|M.ulcerans_Agy99 PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT MSMEG_3496|M.smegmatis_MC2_155 PIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDE MMAR_0775|M.marinum_M PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI Mb0458c|M.bovis_AF2122/97 PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR Rv0450c|M.tuberculosis_H37Rv PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR MLBr_02378|M.leprae_Br4923 PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL MAB_3150|M.abscessus_ATCC_1997 PIRNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDV MAV_4755|M.avium_104 PIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDR *:*.***** ** .:*:* : *::**:***:: : : : : : .:: Mflv_4418|M.gilvum_PYR-GCK LMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEA Mvan_1936|M.vanbaalenii_PYR-1 LMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEA TH_3260|M.thermoresistible__bu LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA MUL_0757|M.ulcerans_Agy99 LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA MSMEG_3496|M.smegmatis_MC2_155 LMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQA MMAR_0775|M.marinum_M LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA Mb0458c|M.bovis_AF2122/97 LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA Rv0450c|M.tuberculosis_H37Rv LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA MLBr_02378|M.leprae_Br4923 LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA MAB_3150|M.abscessus_ATCC_1997 LMPRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKY MAV_4755|M.avium_104 LMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMGQY ***:: :* : *..*: :* : . : .. **: Mflv_4418|M.gilvum_PYR-GCK FDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATV Mvan_1936|M.vanbaalenii_PYR-1 FDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATV TH_3260|M.thermoresistible__bu FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP MUL_0757|M.ulcerans_Agy99 FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ MSMEG_3496|M.smegmatis_MC2_155 FDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSP MMAR_0775|M.marinum_M FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST Mb0458c|M.bovis_AF2122/97 FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP Rv0450c|M.tuberculosis_H37Rv FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP MLBr_02378|M.leprae_Br4923 FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV MAB_3150|M.abscessus_ATCC_1997 FDEAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASV MAV_4755|M.avium_104 FDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASV ** : ******:***.*.* **:*.:: *:*.** :.*: : *.*:* : Mflv_4418|M.gilvum_PYR-GCK EGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIA Mvan_1936|M.vanbaalenii_PYR-1 EGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIA TH_3260|M.thermoresistible__bu EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA MUL_0757|M.ulcerans_Agy99 AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA MSMEG_3496|M.smegmatis_MC2_155 EGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIA MMAR_0775|M.marinum_M EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA Mb0458c|M.bovis_AF2122/97 EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA Rv0450c|M.tuberculosis_H37Rv EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA MLBr_02378|M.leprae_Br4923 AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA MAB_3150|M.abscessus_ATCC_1997 QGIETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILA MAV_4755|M.avium_104 EGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVA *: : : . :::******.: :*:.**.: *: :* **::* Mflv_4418|M.gilvum_PYR-GCK GIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL Mvan_1936|M.vanbaalenii_PYR-1 GIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL TH_3260|M.thermoresistible__bu AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL MUL_0757|M.ulcerans_Agy99 GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI MSMEG_3496|M.smegmatis_MC2_155 GIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGL MMAR_0775|M.marinum_M GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV Mb0458c|M.bovis_AF2122/97 AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI Rv0450c|M.tuberculosis_H37Rv AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI MLBr_02378|M.leprae_Br4923 GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI MAB_3150|M.abscessus_ATCC_1997 GIASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGM MAV_4755|M.avium_104 GISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGL .::.: **: ***::* :.:*: ****** **.:: *:***:** :..: Mflv_4418|M.gilvum_PYR-GCK ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGS Mvan_1936|M.vanbaalenii_PYR-1 ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGS TH_3260|M.thermoresistible__bu EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS MUL_0757|M.ulcerans_Agy99 ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS MSMEG_3496|M.smegmatis_MC2_155 ELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGS MMAR_0775|M.marinum_M ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG Mb0458c|M.bovis_AF2122/97 HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK Rv0450c|M.tuberculosis_H37Rv HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK MLBr_02378|M.leprae_Br4923 ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK MAB_3150|M.abscessus_ATCC_1997 DLHWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGK MAV_4755|M.avium_104 GVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGR ::::*..:::::*****:*****:::*:::*: .*::**:**.*..:* Mflv_4418|M.gilvum_PYR-GCK VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV Mvan_1936|M.vanbaalenii_PYR-1 VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV TH_3260|M.thermoresistible__bu VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI MUL_0757|M.ulcerans_Agy99 VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI MSMEG_3496|M.smegmatis_MC2_155 VVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSI MMAR_0775|M.marinum_M VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI Mb0458c|M.bovis_AF2122/97 VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI Rv0450c|M.tuberculosis_H37Rv VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI MLBr_02378|M.leprae_Br4923 VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI MAB_3150|M.abscessus_ATCC_1997 VVTNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSI MAV_4755|M.avium_104 VVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSI *** *****. ** : .*:* ::.::****.:***.**:::**** *:: Mflv_4418|M.gilvum_PYR-GCK AALLGRWFWWPQKFRSAASERRLARIGVQPAT-----------------A Mvan_1936|M.vanbaalenii_PYR-1 AALLGRWFWWPQKVRSHASQRRLAALNH---------------------- TH_3260|M.thermoresistible__bu ATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP------------------A MUL_0757|M.ulcerans_Agy99 AALLGKWFWWPQVVRQRPAPQPWPTPAPTPP------------------P MSMEG_3496|M.smegmatis_MC2_155 AALMGKWFWWPQRVRQRPLPAPWPQPVQRDPE-----------------D MMAR_0775|M.marinum_M AALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDT Mb0458c|M.bovis_AF2122/97 AALLGRWFWWPLRVRSRPARTPTVPSETQPAG-----------------R Rv0450c|M.tuberculosis_H37Rv AALLGRWFWWPLRVRSRPARTPTVPSETQPAG-----------------R MLBr_02378|M.leprae_Br4923 AALLGRWFWWPQQGRTRPLLTVAAPVGLPPD------------------R MAB_3150|M.abscessus_ATCC_1997 AALLGRWFWWPLR-----VRTHGTAGV----------------------- MAV_4755|M.avium_104 AAALGHWFWWPINTIRMTRRTHHDEEAHTAPIR----------------Q *: :*:***** Mflv_4418|M.gilvum_PYR-GCK GR---------- Mvan_1936|M.vanbaalenii_PYR-1 ------------ TH_3260|M.thermoresistible__bu TTDRVSV----- MUL_0757|M.ulcerans_Agy99 ATTSV------- MSMEG_3496|M.smegmatis_MC2_155 ALNRV------- MMAR_0775|M.marinum_M NTERLAVSSPHY Mb0458c|M.bovis_AF2122/97 PLAMSSDRLG-- Rv0450c|M.tuberculosis_H37Rv PLAMSSDRLG-- MLBr_02378|M.leprae_Br4923 SLVYSD------ MAB_3150|M.abscessus_ATCC_1997 ------------ MAV_4755|M.avium_104 PALR--------