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M. abscessus ATCC 19977 MAB_3150 (-)

annotation: MmpL family protein
coordinates: 3195952 - 3198777
length: 941

MRHGSGDHTARPPRIARLIRTLSIPIILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTG
KVFGEFDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPLTASGAQSADGKSAYV
QVNLAGDQGTTLANESVDAVRKIIAETPGPAGVQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLML
LLVYRSVITTIVALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFLLGRYHEAR
HRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPLFRSMGVPCALVILVIVAAALTLAPAILA
LGSRFGLFEPKRKYDEGGWRRIGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVG
YAAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRVQAITRPLGTPIEHSSIPFQ
IGLQGAGQIQNMKYMKDRMADMLTMANQMGILIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDL
MYTFDDFFRPIRNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLMPRVLAEFPP
MIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFDEAKNDDSFYLPPEVFDNPDFKRGLKMFLS
PDGKAVRMTVSHQGNPASVQGIETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAG
IASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDLHWFVVPLSVIILLAVGSDY
NLLLIARFKEELHGGLKTGFIRAMGGSGKVVTNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLI
VRSFMMPSIAALLGRWFWWPLRVRTHGTAGV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3150--100% (941)MmpL family protein
M. abscessus ATCC 19977MAB_2301-0.059.47% (940) putative membrane protein, mmpL
M. abscessus ATCC 19977MAB_1134c-0.058.34% (941) membrane protein MmpL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.059.38% (928) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.057.00% (921) transport protein
M. tuberculosis H37RvRv0450cmmpL40.059.38% (928) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.060.60% (929) hypothetical protein MLBr_02378
M. marinum MMMAR_0775-0.061.41% (933) MmpL family transport protein
M. avium 104MAV_4755-0.062.39% (920) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.059.40% (931) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.057.48% (929) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.058.53% (926) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.057.03% (924) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1       ---------------------------------MADAGRSGIGRIIHLLA
TH_3260|M.thermoresistible__bu      -----------MTANPGHVRTDEAPTDRLDIK-VSTHGPSFISTWIRRLS
MUL_0757|M.ulcerans_Agy99           -----------MTAT-----TTDTPTDVVPPA-EHPPRP-FIPRMIRTFA
MSMEG_3496|M.smegmatis_MC2_155      -----------MSNP-----SHDAPTDAMGVSGPKHARPGGIAKWIRVLA
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
Mb0458c|M.bovis_AF2122/97           ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
Rv0450c|M.tuberculosis_H37Rv        ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
MLBr_02378|M.leprae_Br4923          ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA
MAB_3150|M.abscessus_ATCC_1997      ---------------------------MRHGSGDHTARPPRIARLIRTLS
MAV_4755|M.avium_104                -----------------------------------------------MLS
                                                                                    ::

Mflv_4418|M.gilvum_PYR-GCK          VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Mvan_1936|M.vanbaalenii_PYR-1       VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF
TH_3260|M.thermoresistible__bu      LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
MUL_0757|M.ulcerans_Agy99           VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
MSMEG_3496|M.smegmatis_MC2_155      VPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVF
MMAR_0775|M.marinum_M               VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
Mb0458c|M.bovis_AF2122/97           VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
Rv0450c|M.tuberculosis_H37Rv        VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923          VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
MAB_3150|M.abscessus_ATCC_1997      IPIILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVF
MAV_4755|M.avium_104                LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF
                                    :*: : *: :        *.*: *.. ::* ::.  * :  :* : *  *

Mflv_4418|M.gilvum_PYR-GCK          EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD
Mvan_1936|M.vanbaalenii_PYR-1       DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD
TH_3260|M.thermoresistible__bu      DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD
MUL_0757|M.ulcerans_Agy99           REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD
MSMEG_3496|M.smegmatis_MC2_155      EEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGD
MMAR_0775|M.marinum_M               NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD
Mb0458c|M.bovis_AF2122/97           KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
Rv0450c|M.tuberculosis_H37Rv        KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923          NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
MAB_3150|M.abscessus_ATCC_1997      GEFDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGD
MAV_4755|M.avium_104                NEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSD
                                     *  ::*  *:::**.. *.  *: :** :: .*. *  ::: : * *.*

Mflv_4418|M.gilvum_PYR-GCK          PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---AP
Mvan_1936|M.vanbaalenii_PYR-1       PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---AP
TH_3260|M.thermoresistible__bu      PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP
MUL_0757|M.ulcerans_Agy99           PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---QAP
MSMEG_3496|M.smegmatis_MC2_155      PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---AP
MMAR_0775|M.marinum_M               PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP
Mb0458c|M.bovis_AF2122/97           PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
Rv0450c|M.tuberculosis_H37Rv        PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
MLBr_02378|M.leprae_Br4923          PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP
MAB_3150|M.abscessus_ATCC_1997      PLTASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAETP---GP
MAV_4755|M.avium_104                PLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP---AP
                                    ****.* ** ** ::***    * **   : *:: :*: ::       .*

Mflv_4418|M.gilvum_PYR-GCK          PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM
Mvan_1936|M.vanbaalenii_PYR-1       PGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATM
TH_3260|M.thermoresistible__bu      EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV
MUL_0757|M.ulcerans_Agy99           PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA
MSMEG_3496|M.smegmatis_MC2_155      PGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTV
MMAR_0775|M.marinum_M               PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV
Mb0458c|M.bovis_AF2122/97           PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
Rv0450c|M.tuberculosis_H37Rv        PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
MLBr_02378|M.leprae_Br4923          PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV
MAB_3150|M.abscessus_ATCC_1997      AGVQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITT
MAV_4755|M.avium_104                PGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTT
                                     *: .:*:* :   **    .. *:      :. *:   ** *:**. * 

Mflv_4418|M.gilvum_PYR-GCK          VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI
Mvan_1936|M.vanbaalenii_PYR-1       VLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAI
TH_3260|M.thermoresistible__bu      LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI
MUL_0757|M.ulcerans_Agy99           AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI
MSMEG_3496|M.smegmatis_MC2_155      ILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAI
MMAR_0775|M.marinum_M               ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI
Mb0458c|M.bovis_AF2122/97           VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
Rv0450c|M.tuberculosis_H37Rv        VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
MLBr_02378|M.leprae_Br4923          ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI
MAB_3150|M.abscessus_ATCC_1997      IVALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVI
MAV_4755|M.avium_104                VLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVI
                                       *  :     . :*  *  .    ***: :*..::. : ** ..** *

Mflv_4418|M.gilvum_PYR-GCK          FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
Mvan_1936|M.vanbaalenii_PYR-1       FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
TH_3260|M.thermoresistible__bu      FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL
MUL_0757|M.ulcerans_Agy99           FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL
MSMEG_3496|M.smegmatis_MC2_155      FLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRM
MMAR_0775|M.marinum_M               FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL
Mb0458c|M.bovis_AF2122/97           FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM
Rv0450c|M.tuberculosis_H37Rv        FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM
MLBr_02378|M.leprae_Br4923          FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM
MAB_3150|M.abscessus_ATCC_1997      FLLGRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRL
MAV_4755|M.avium_104                FLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARL
                                    *  ***:***  . .:  :::* : .. **:*.**:** **  **  :*:

Mflv_4418|M.gilvum_PYR-GCK          PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW
Mvan_1936|M.vanbaalenii_PYR-1       PYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGW
TH_3260|M.thermoresistible__bu      PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW
MUL_0757|M.ulcerans_Agy99           PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW
MSMEG_3496|M.smegmatis_MC2_155      PYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGW
MMAR_0775|M.marinum_M               PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW
Mb0458c|M.bovis_AF2122/97           PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
Rv0450c|M.tuberculosis_H37Rv        PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
MLBr_02378|M.leprae_Br4923          PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW
MAB_3150|M.abscessus_ATCC_1997      PLFRSMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPKRKYDEGGW
MAV_4755|M.avium_104                PYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVRGW
                                    * *:::* * *:   : : .:**:..*:: : : *   ::***      *

Mflv_4418|M.gilvum_PYR-GCK          RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV
Mvan_1936|M.vanbaalenii_PYR-1       RRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANV
TH_3260|M.thermoresistible__bu      RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA
MUL_0757|M.ulcerans_Agy99           RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE
MSMEG_3496|M.smegmatis_MC2_155      RKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANT
MMAR_0775|M.marinum_M               RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV
Mb0458c|M.bovis_AF2122/97           RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
Rv0450c|M.tuberculosis_H37Rv        RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
MLBr_02378|M.leprae_Br4923          RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ
MAB_3150|M.abscessus_ATCC_1997      RRIGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKV
MAV_4755|M.avium_104                RKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANA
                                    *::*. :**** *::  : .::::*:::*  * ..*. : : *   *:: 

Mflv_4418|M.gilvum_PYR-GCK          GYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVA
Mvan_1936|M.vanbaalenii_PYR-1       GYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVA
TH_3260|M.thermoresistible__bu      GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS
MUL_0757|M.ulcerans_Agy99           GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS
MSMEG_3496|M.smegmatis_MC2_155      GYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGIS
MMAR_0775|M.marinum_M               GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA
Mb0458c|M.bovis_AF2122/97           GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
Rv0450c|M.tuberculosis_H37Rv        GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
MLBr_02378|M.leprae_Br4923          GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS
MAB_3150|M.abscessus_ATCC_1997      GYAAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVG
MAV_4755|M.avium_104                AMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIE
                                    .  .*::**  **::**:*::*:***:*:.:*:*:::::*:  *   *: 

Mflv_4418|M.gilvum_PYR-GCK          RVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAM
Mvan_1936|M.vanbaalenii_PYR-1       RVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAM
TH_3260|M.thermoresistible__bu      RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM
MUL_0757|M.ulcerans_Agy99           RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI
MSMEG_3496|M.smegmatis_MC2_155      RVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEM
MMAR_0775|M.marinum_M               RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM
Mb0458c|M.bovis_AF2122/97           RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
Rv0450c|M.tuberculosis_H37Rv        RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
MLBr_02378|M.leprae_Br4923          RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM
MAB_3150|M.abscessus_ATCC_1997      RVQAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQM
MAV_4755|M.avium_104                RVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADEL
                                    *** :*** * .:.*::*** :.  .:    . :: .:   .:*  .  :

Mflv_4418|M.gilvum_PYR-GCK          QTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFR
Mvan_1936|M.vanbaalenii_PYR-1       QTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVR
TH_3260|M.thermoresistible__bu      QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR
MUL_0757|M.ulcerans_Agy99           QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR
MSMEG_3496|M.smegmatis_MC2_155      QKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLR
MMAR_0775|M.marinum_M               QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR
Mb0458c|M.bovis_AF2122/97           ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
Rv0450c|M.tuberculosis_H37Rv        ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
MLBr_02378|M.leprae_Br4923          AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR
MAB_3150|M.abscessus_ATCC_1997      GILIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFR
MAV_4755|M.avium_104                DKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFR
                                       :  : .:  :   :    . :            .:*: :  :*** *

Mflv_4418|M.gilvum_PYR-GCK          PVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDE
Mvan_1936|M.vanbaalenii_PYR-1       PVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDA
TH_3260|M.thermoresistible__bu      PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND
MUL_0757|M.ulcerans_Agy99           PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT
MSMEG_3496|M.smegmatis_MC2_155      PIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDE
MMAR_0775|M.marinum_M               PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI
Mb0458c|M.bovis_AF2122/97           PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
Rv0450c|M.tuberculosis_H37Rv        PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
MLBr_02378|M.leprae_Br4923          PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL
MAB_3150|M.abscessus_ATCC_1997      PIRNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDV
MAV_4755|M.avium_104                PIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDR
                                    *:*.***** ** .:*:* : *::**:***:: : : :  :   : .:: 

Mflv_4418|M.gilvum_PYR-GCK          LMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEA
Mvan_1936|M.vanbaalenii_PYR-1       LMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEA
TH_3260|M.thermoresistible__bu      LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA
MUL_0757|M.ulcerans_Agy99           LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA
MSMEG_3496|M.smegmatis_MC2_155      LMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQA
MMAR_0775|M.marinum_M               LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA
Mb0458c|M.bovis_AF2122/97           LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
Rv0450c|M.tuberculosis_H37Rv        LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
MLBr_02378|M.leprae_Br4923          LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA
MAB_3150|M.abscessus_ATCC_1997      LMPRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKY
MAV_4755|M.avium_104                LMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMGQY
                                    ***::   :*  :  *..*:  :*    :  .   :     ..   **: 

Mflv_4418|M.gilvum_PYR-GCK          FDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATV
Mvan_1936|M.vanbaalenii_PYR-1       FDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATV
TH_3260|M.thermoresistible__bu      FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP
MUL_0757|M.ulcerans_Agy99           FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ
MSMEG_3496|M.smegmatis_MC2_155      FDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSP
MMAR_0775|M.marinum_M               FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST
Mb0458c|M.bovis_AF2122/97           FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
Rv0450c|M.tuberculosis_H37Rv        FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
MLBr_02378|M.leprae_Br4923          FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV
MAB_3150|M.abscessus_ATCC_1997      FDEAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASV
MAV_4755|M.avium_104                FDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASV
                                    ** : ******:***.*.* **:*.:: *:*.** :.*: : *.*:* : 

Mflv_4418|M.gilvum_PYR-GCK          EGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIA
Mvan_1936|M.vanbaalenii_PYR-1       EGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIA
TH_3260|M.thermoresistible__bu      EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA
MUL_0757|M.ulcerans_Agy99           AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA
MSMEG_3496|M.smegmatis_MC2_155      EGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIA
MMAR_0775|M.marinum_M               EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA
Mb0458c|M.bovis_AF2122/97           EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
Rv0450c|M.tuberculosis_H37Rv        EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
MLBr_02378|M.leprae_Br4923          AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA
MAB_3150|M.abscessus_ATCC_1997      QGIETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILA
MAV_4755|M.avium_104                EGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVA
                                     *:  :  :   . :::******.: :*:.**.:   *: :*   **::*

Mflv_4418|M.gilvum_PYR-GCK          GIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
Mvan_1936|M.vanbaalenii_PYR-1       GIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
TH_3260|M.thermoresistible__bu      AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL
MUL_0757|M.ulcerans_Agy99           GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI
MSMEG_3496|M.smegmatis_MC2_155      GIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGL
MMAR_0775|M.marinum_M               GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV
Mb0458c|M.bovis_AF2122/97           AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
Rv0450c|M.tuberculosis_H37Rv        AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
MLBr_02378|M.leprae_Br4923          GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI
MAB_3150|M.abscessus_ATCC_1997      GIASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGM
MAV_4755|M.avium_104                GISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGL
                                    .::.: **: ***::* :.:*: ******  **.:: *:***:** :..:

Mflv_4418|M.gilvum_PYR-GCK          ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGS
Mvan_1936|M.vanbaalenii_PYR-1       ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGS
TH_3260|M.thermoresistible__bu      EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS
MUL_0757|M.ulcerans_Agy99           ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS
MSMEG_3496|M.smegmatis_MC2_155      ELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGS
MMAR_0775|M.marinum_M               ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG
Mb0458c|M.bovis_AF2122/97           HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
Rv0450c|M.tuberculosis_H37Rv        HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
MLBr_02378|M.leprae_Br4923          ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK
MAB_3150|M.abscessus_ATCC_1997      DLHWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGK
MAV_4755|M.avium_104                GVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGR
                                     ::::*..:::::*****:*****:::*:::*: .*::**:**.*..:* 

Mflv_4418|M.gilvum_PYR-GCK          VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
Mvan_1936|M.vanbaalenii_PYR-1       VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
TH_3260|M.thermoresistible__bu      VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI
MUL_0757|M.ulcerans_Agy99           VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI
MSMEG_3496|M.smegmatis_MC2_155      VVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSI
MMAR_0775|M.marinum_M               VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Mb0458c|M.bovis_AF2122/97           VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Rv0450c|M.tuberculosis_H37Rv        VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
MLBr_02378|M.leprae_Br4923          VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI
MAB_3150|M.abscessus_ATCC_1997      VVTNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSI
MAV_4755|M.avium_104                VVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSI
                                    *** *****. **  : .*:* ::.::****.:***.**:::**** *::

Mflv_4418|M.gilvum_PYR-GCK          AALLGRWFWWPQKFRSAASERRLARIGVQPAT-----------------A
Mvan_1936|M.vanbaalenii_PYR-1       AALLGRWFWWPQKVRSHASQRRLAALNH----------------------
TH_3260|M.thermoresistible__bu      ATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP------------------A
MUL_0757|M.ulcerans_Agy99           AALLGKWFWWPQVVRQRPAPQPWPTPAPTPP------------------P
MSMEG_3496|M.smegmatis_MC2_155      AALMGKWFWWPQRVRQRPLPAPWPQPVQRDPE-----------------D
MMAR_0775|M.marinum_M               AALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDT
Mb0458c|M.bovis_AF2122/97           AALLGRWFWWPLRVRSRPARTPTVPSETQPAG-----------------R
Rv0450c|M.tuberculosis_H37Rv        AALLGRWFWWPLRVRSRPARTPTVPSETQPAG-----------------R
MLBr_02378|M.leprae_Br4923          AALLGRWFWWPQQGRTRPLLTVAAPVGLPPD------------------R
MAB_3150|M.abscessus_ATCC_1997      AALLGRWFWWPLR-----VRTHGTAGV-----------------------
MAV_4755|M.avium_104                AAALGHWFWWPINTIRMTRRTHHDEEAHTAPIR----------------Q
                                    *: :*:*****                                       

Mflv_4418|M.gilvum_PYR-GCK          GR----------
Mvan_1936|M.vanbaalenii_PYR-1       ------------
TH_3260|M.thermoresistible__bu      TTDRVSV-----
MUL_0757|M.ulcerans_Agy99           ATTSV-------
MSMEG_3496|M.smegmatis_MC2_155      ALNRV-------
MMAR_0775|M.marinum_M               NTERLAVSSPHY
Mb0458c|M.bovis_AF2122/97           PLAMSSDRLG--
Rv0450c|M.tuberculosis_H37Rv        PLAMSSDRLG--
MLBr_02378|M.leprae_Br4923          SLVYSD------
MAB_3150|M.abscessus_ATCC_1997      ------------
MAV_4755|M.avium_104                PALR--------