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MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPIILGWVLLTVLVNVVVPSLEVV SEQHSAPMTPMDAPSMKAMMRLGHNFREFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHI QDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTHEPAGVKAYVTGPAALSDDM HLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANIL TMLAIAAGTDYGIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPWFNTMG APVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMV ALPGFKTSYNDRYYLPASAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTV GIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQVLIDTTERMYAVMREL DTTTTDMARVTAETSTITDELRDHLAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEK FSELTEDIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFDASKND DFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKV YLGGTAATFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDL FGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVVTAAGLVFAFTMASML GSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | - | 100% (973) | transmembrane transport protein MmpL4_1 |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 56.46% (937) | transmembrane transport protein, MmpL5 |
| M. ulcerans Agy99 | MUL_2007 | mmpL7 | 1e-59 | 23.85% (914) | transmembrane transport protein MmpL7 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.60% (929) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 58.63% (921) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 60.71% (929) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 57.83% (920) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 57.02% (926) | MmpL family protein |
| M. marinum M | MMAR_3744 | mmpL4_1 | 0.0 | 99.49% (973) | transmembrane transport protein MmpL4_1 |
| M. avium 104 | MAV_1755 | - | 0.0 | 81.37% (961) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0576 | - | 0.0 | 69.11% (929) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 56.62% (922) | PUTATIVE MmpL4 protein |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 56.66% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 --------------------MSTKFANDSNTNARPEK----------PFI
Rv0450c|M.tuberculosis_H37Rv --------------------MSTKFANDSNTNARPEK----------PFI
MLBr_02378|M.leprae_Br4923 --------------------MTVKCANDLDTHTKP------------PFV
TH_3260|M.thermoresistible__bu --------------------MTANPGHVRTDEAPTDRLDIKVSTHGPSFI
Mvan_3189|M.vanbaalenii_PYR-1 --------------------MSAPVSDARTDEFPAAR-----QPHRP-FI
Mflv_4418|M.gilvum_PYR-GCK ---------------------MADAGRSG--------------------I
MAB_3150|M.abscessus_ATCC_1997 --------------------MRHGSGDHTARPPR---------------I
MUL_3688|M.ulcerans_Agy99 MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHR----------PVI
MMAR_3744|M.marinum_M MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHR----------PVI
MAV_1755|M.avium_104 MSDASNKTQPDLSAADTGPINVKGLS----KAERGHR----------PYL
MSMEG_0576|M.smegmatis_MC2_155 --------------------MIQGLH-----NRSDSR----------PLL
:
Mb0458c|M.bovis_AF2122/97 ARMIHAFAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEA
Rv0450c|M.tuberculosis_H37Rv ARMIHAFAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEA
MLBr_02378|M.leprae_Br4923 ARMIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIA
TH_3260|M.thermoresistible__bu STWIRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVA
Mvan_3189|M.vanbaalenii_PYR-1 PRMIRLFAVPIILGWIALIVILNVTVPQLEAVGEARAVSMSPNEAPSLIS
Mflv_4418|M.gilvum_PYR-GCK GRIIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMS
MAB_3150|M.abscessus_ATCC_1997 ARLIRTLSIPIILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIA
MUL_3688|M.ulcerans_Agy99 PHTIRILAVPIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKA
MMAR_3744|M.marinum_M PHTIRILAVPIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKA
MAV_1755|M.avium_104 PHAIRIFAVPIILGWLFVTVLVNVIVPTLEKVGEAHSAPMTPLDAPSMKA
MSMEG_0576|M.smegmatis_MC2_155 PHALRVLAIPVILFWVAFAAVVNIIAPQLEIVGEEHSAPMAPEDAPSLTG
:: :::*::: *: . .: * *: *.: ::. ::. :*** .
Mb0458c|M.bovis_AF2122/97 MGRIGMVFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQ
Rv0450c|M.tuberculosis_H37Rv MGRIGMVFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQ
MLBr_02378|M.leprae_Br4923 MQKMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQ
TH_3260|M.thermoresistible__bu MKRVGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVE
Mvan_3189|M.vanbaalenii_PYR-1 MKKVGELFREGDSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQ
Mflv_4418|M.gilvum_PYR-GCK MKRVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQ
MAB_3150|M.abscessus_ATCC_1997 MMHTGKVFGEFDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQ
MUL_3688|M.ulcerans_Agy99 MMRLGHNFREFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQ
MMAR_3744|M.marinum_M MMRLGHNFREFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQ
MAV_1755|M.avium_104 MMRLGHNFHEFDSNSTVMIVLEGQQPLGPDAHKYYDNLIRQLRQDPKHIQ
MSMEG_0576|M.smegmatis_MC2_155 MHRMGGNFQEFDSNSTVMVVIEGQEPLGPDAHAYYDEIIRKLRQDPEHIQ
* : * * * .*:* *:::**:. *. *: :** :: .*. * :::
Mb0458c|M.bovis_AF2122/97 SVQDLWGDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVE
Rv0450c|M.tuberculosis_H37Rv SVQDLWGDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVE
MLBr_02378|M.leprae_Br4923 SVQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVV
TH_3260|M.thermoresistible__bu NVQDLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIA
Mvan_3189|M.vanbaalenii_PYR-1 SVQDFWSDPLTASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVR
Mflv_4418|M.gilvum_PYR-GCK HIADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVD
MAB_3150|M.abscessus_ATCC_1997 HISDYWGDPLTASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIA
MUL_3688|M.ulcerans_Agy99 HIQDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVIN
MMAR_3744|M.marinum_M HIQDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVIN
MAV_1755|M.avium_104 HIQDFWGDRLTAAGAQSADAKGAYVQVNLAGNQGTTLANESVDAVRKVID
MSMEG_0576|M.smegmatis_MC2_155 HIQDFWGDTLTAAGAQSADGKAAYVMLNLAGEQGQTLANDGVQEVRQVIA
: * *.* ***.* ** *.*.*** : * *:** *::.: .:.::
Mb0458c|M.bovis_AF2122/97 STP---APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLL
Rv0450c|M.tuberculosis_H37Rv STP---APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLL
MLBr_02378|M.leprae_Br4923 QTP---APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLL
TH_3260|M.thermoresistible__bu TVSEEMAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLF
Mvan_3189|M.vanbaalenii_PYR-1 SLE---PPPGVRAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLL
Mflv_4418|M.gilvum_PYR-GCK RTP---APPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLI
MAB_3150|M.abscessus_ATCC_1997 ETP---GPAGVQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLL
MUL_3688|M.ulcerans_Agy99 RTH---EPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLL
MMAR_3744|M.marinum_M RTH---EPAGVKAYVTGPAALSDDMHLIGNASLAKITMFTLGAIAVMLLL
MAV_1755|M.avium_104 ENK---APPGVKAYVTGPAALSDDMHIIGNASLAKITLFTLGAIAIMLLL
MSMEG_0576|M.smegmatis_MC2_155 DTP---APPGVQAYAAGPAALTDDLHVIGNASLGKITLFTLVAIAVMLLI
* *: *:.:* :. * .: *: :. .: **:
Mb0458c|M.bovis_AF2122/97 VYRSIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAI
Rv0450c|M.tuberculosis_H37Rv VYRSIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAI
MLBr_02378|M.leprae_Br4923 VYRSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAI
TH_3260|M.thermoresistible__bu VYRSVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAI
Mvan_3189|M.vanbaalenii_PYR-1 VYRSIVTVLLTLVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAI
Mflv_4418|M.gilvum_PYR-GCK VFRSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVI
MAB_3150|M.abscessus_ATCC_1997 VYRSVITTIVALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGI
MUL_3688|M.ulcerans_Agy99 VYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAI
MMAR_3744|M.marinum_M VYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAI
MAV_1755|M.avium_104 VYRSIVTTLVQLFMTFVALACSRGVVAVLAYHNAFGLTTFAANILTMLAI
MSMEG_0576|M.smegmatis_MC2_155 VYRSIVTTLIQLVLTGVGLLASRGLISVLATHDVFGLTTFAGNILTMLAI
*:**. * :: *. . :*::: *. :**: :* .::. : *
Mb0458c|M.bovis_AF2122/97 AAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGAT
Rv0450c|M.tuberculosis_H37Rv AAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGAT
MLBr_02378|M.leprae_Br4923 AAGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGAT
TH_3260|M.thermoresistible__bu AIAVDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGAT
Mvan_3189|M.vanbaalenii_PYR-1 AAATDYAIFLIGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGAT
Mflv_4418|M.gilvum_PYR-GCK AAGTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAM
MAB_3150|M.abscessus_ATCC_1997 AAGTDYVIFLLGRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGAT
MUL_3688|M.ulcerans_Agy99 AAGTDYGIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGAT
MMAR_3744|M.marinum_M AAGTDYGIFLVGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGLTIAGAT
MAV_1755|M.avium_104 AAGTDYGIFLIGRYQEALAAGEDRESAYYTTFKGVAPVVLGSGLTIAGAT
MSMEG_0576|M.smegmatis_MC2_155 AAATDYGIFLFGRYREARGAGEDPETAYYTTFKSVSPVIVGSGLTIAGAT
* ..** ** ***:** . : *::* : .. *::.***** **
Mb0458c|M.bovis_AF2122/97 FCLSFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPK
Rv0450c|M.tuberculosis_H37Rv FCLSFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPK
MLBr_02378|M.leprae_Br4923 FCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPK
TH_3260|M.thermoresistible__bu FCLSFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPK
Mvan_3189|M.vanbaalenii_PYR-1 YCLSFTRLPYFQTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPK
Mflv_4418|M.gilvum_PYR-GCK LCLSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPK
MAB_3150|M.abscessus_ATCC_1997 LCLSLTRLPLFRSMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPK
MUL_3688|M.ulcerans_Agy99 YCLSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESK
MMAR_3744|M.marinum_M YCLSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-LFESK
MAV_1755|M.avium_104 YCLSFSRLPWFNTMGAPVAIGMLVVVLAGVTLGPAVVFVGSRFH-FFE--
MSMEG_0576|M.smegmatis_MC2_155 YCLSFARLPYFSTMGAPVAIGMIVVVASSVTMGPAVLFLGSKVG-LYEAK
***::*:* * ::* * *: :: : .: : *:: :.::. :
Mb0458c|M.bovis_AF2122/97 RLLK-VRGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDY
Rv0450c|M.tuberculosis_H37Rv RLLK-VRGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDY
MLBr_02378|M.leprae_Br4923 RLIK-VRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAY
TH_3260|M.thermoresistible__bu RAAR-VRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNY
Mvan_3189|M.vanbaalenii_PYR-1 RAMR-IRGWRKIGAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTY
Mflv_4418|M.gilvum_PYR-GCK RAIS-SRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDY
MAB_3150|M.abscessus_ATCC_1997 RKYD-EGGWRRIGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQY
MUL_3688|M.ulcerans_Agy99 RAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYY
MMAR_3744|M.marinum_M RAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYY
MAV_1755|M.avium_104 RQAKRGRLWRRVGTAVVRWPAPVLAVSAAVVLVGMIALPSFHTSYNDRHY
MSMEG_0576|M.smegmatis_MC2_155 RAAK-GRFWRRVGTAVVRWPAPILVASAFIVLIGVVAVPGYRPAYNDRWY
* **::*. ***** *:: : :.::*::::*.: . *. * *
Mb0458c|M.bovis_AF2122/97 LPDFIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAK
Rv0450c|M.tuberculosis_H37Rv LPDFIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAK
MLBr_02378|M.leprae_Br4923 LPASIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLAR
TH_3260|M.thermoresistible__bu LPASFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAK
Mvan_3189|M.vanbaalenii_PYR-1 LPADLPANEGYAVADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAK
Mflv_4418|M.gilvum_PYR-GCK LPEDIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAK
MAB_3150|M.abscessus_ATCC_1997 MPDNVPSKVGYAAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAK
MUL_3688|M.ulcerans_Agy99 LPASAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAK
MMAR_3744|M.marinum_M LPASAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAK
MAV_1755|M.avium_104 LPLSAPSNQGQEAANRHFSEARMNPDLLMIESDHDMRNPADMLVLDRVAK
MSMEG_0576|M.smegmatis_MC2_155 LPDDAPVNIGFAAADRHFTQARMNPDILMVEADHDMRNPADMLVLDRVAK
:* * : * .*::** **::*::*::*::**:*:.:*:*:::::*:
Mb0458c|M.bovis_AF2122/97 GIFRVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRAN
Rv0450c|M.tuberculosis_H37Rv GIFRVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRAN
MLBr_02378|M.leprae_Br4923 GIFRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMN
TH_3260|M.thermoresistible__bu AVFQVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMA
Mvan_3189|M.vanbaalenii_PYR-1 AIFKVEGIARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMA
Mflv_4418|M.gilvum_PYR-GCK SVFRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMA
MAB_3150|M.abscessus_ATCC_1997 TAFHARGVGRVQAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMA
MUL_3688|M.ulcerans_Agy99 NVIRTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMA
MMAR_3744|M.marinum_M NVIRTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMA
MAV_1755|M.avium_104 NEMRTLGIAMVQDITRPLGIPIQHSSIPFQNSVQSQTTMQNMGFLKERMN
MSMEG_0576|M.smegmatis_MC2_155 NVLRTQGIAMVQSITRPLGIPIQHSSIPFQTAIQGQTSNLNLPFQRAQLD
::. *:. :* **** * .:.*::*** . *. . : : :
Mb0458c|M.bovis_AF2122/97 DMLKQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDH
Rv0450c|M.tuberculosis_H37Rv DMLKQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDH
MLBr_02378|M.leprae_Br4923 DLLRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDE
TH_3260|M.thermoresistible__bu DMLVQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDS
Mvan_3189|M.vanbaalenii_PYR-1 DMLVQADEMANTIATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDS
Mflv_4418|M.gilvum_PYR-GCK DMLVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDN
MAB_3150|M.abscessus_ATCC_1997 DMLTMANQMGILIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDL
MUL_3688|M.ulcerans_Agy99 DMTKMADEMQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDH
MMAR_3744|M.marinum_M DMTKMADEMQVLIDTTERMYAVMRDLDTTTTDMARVTAETSTITDELRDH
MAV_1755|M.avium_104 DILKMADDLQTQIDTTQRQYEVSMDLANAADDSAKTTAVTSQITDSLRDH
MSMEG_0576|M.smegmatis_MC2_155 NQLKMVEATNQSIAIMEKQYELSLRQTKLTQDSAEKSRELLEVTKQLRDN
: .: : : : .:**
Mb0458c|M.bovis_AF2122/97 VADFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVL
Rv0450c|M.tuberculosis_H37Rv VADFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVL
MLBr_02378|M.leprae_Br4923 IANFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSI
TH_3260|M.thermoresistible__bu ISEFDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNM
Mvan_3189|M.vanbaalenii_PYR-1 IANFDDFFRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREI
Mflv_4418|M.gilvum_PYR-GCK LADFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISEL
MAB_3150|M.abscessus_ATCC_1997 MYTFDDFFRPIRNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGM
MUL_3688|M.ulcerans_Agy99 LAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSEL
MMAR_3744|M.marinum_M LAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSEL
MAV_1755|M.avium_104 IADFDDTFRPIRTYFYWEKHCYDIPVCIGLRSLFDTFDGFDQLAEQFHYL
MSMEG_0576|M.smegmatis_MC2_155 IANFDDQFRPLRNYFYWEPHCFDIPMCAAARSLFDSLDTVDELTDRTSAV
: *** :**:*.***** ** .:*:* *::**::* .: : : :
Mb0458c|M.bovis_AF2122/97 LGDLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMS
Rv0450c|M.tuberculosis_H37Rv LGDLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMS
MLBr_02378|M.leprae_Br4923 VGDIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELS
TH_3260|M.thermoresistible__bu LPHMHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQ
Mvan_3189|M.vanbaalenii_PYR-1 LPDMKRLDSLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMS
Mflv_4418|M.gilvum_PYR-GCK IPDLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMS
MAB_3150|M.abscessus_ATCC_1997 VVNVDKIDVLMPRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDEST
MUL_3688|M.ulcerans_Agy99 TEDIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELS
MMAR_3744|M.marinum_M TEDIQHTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELS
MAV_1755|M.avium_104 TTDIAHTAKASRDLTALFPTLITTLKTTRGITLTLYQTFKAMIDQMEAMS
MSMEG_0576|M.smegmatis_MC2_155 QVNTDELADLAPQLTALLPQTIASMKTSRDLSLASYNSQKALLDQMQAMN
. . : :* : :.. : * : . :*
Mb0458c|M.bovis_AF2122/97 DNATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFII
Rv0450c|M.tuberculosis_H37Rv DNATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFII
MLBr_02378|M.leprae_Br4923 DNANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFII
TH_3260|M.thermoresistible__bu ENANAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFII
Mvan_3189|M.vanbaalenii_PYR-1 EDADAMGEAFDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFII
Mflv_4418|M.gilvum_PYR-GCK EDADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFII
MAB_3150|M.abscessus_ATCC_1997 KNSTLMGKYFDEAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTV
MUL_3688|M.ulcerans_Agy99 NTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFI
MMAR_3744|M.marinum_M NTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFI
MAV_1755|M.avium_104 NTAVVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFI
MSMEG_0576|M.smegmatis_MC2_155 DTALAMGQSFDEAKNDDFFYLPPEAFQNPDFERGLKMFLSPDGKSARMFI
. : **: ** : *** ****** *.* **: .:. *:*.**::.*: :
Mb0458c|M.bovis_AF2122/97 LHRGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISE
Rv0450c|M.tuberculosis_H37Rv LHRGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISE
MLBr_02378|M.leprae_Br4923 LHRGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDE
TH_3260|M.thermoresistible__bu SHQGDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSD
Mvan_3189|M.vanbaalenii_PYR-1 SHEGDPLSPEGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQD
Mflv_4418|M.gilvum_PYR-GCK SHEGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSD
MAB_3150|M.abscessus_ATCC_1997 SHQGNPASVQGIETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQE
MUL_3688|M.ulcerans_Agy99 THQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMAD
MMAR_3744|M.marinum_M THQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMAD
MAV_1755|M.avium_104 THQGDPMSPEGIKRVDAERTAAQEGLKQSSLSDARVYLGGTAATFKDMAD
MSMEG_0576|M.smegmatis_MC2_155 THQSDPATPEGIARVNAERTAAQEGLKMSSLSDAKIFLGGTAATYKDMSD
*..:* : *: : : *. :.:* :.*..: :::.****. :*: :
Mb0458c|M.bovis_AF2122/97 GAQWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSV
Rv0450c|M.tuberculosis_H37Rv GAQWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSV
MLBr_02378|M.leprae_Br4923 GANWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSV
TH_3260|M.thermoresistible__bu GTKYDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSV
Mvan_3189|M.vanbaalenii_PYR-1 GNNYDLLIAGISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSV
Mflv_4418|M.gilvum_PYR-GCK GAFYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSV
MAB_3150|M.abscessus_ATCC_1997 GAKYDLILAGIASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSV
MUL_3688|M.ulcerans_Agy99 GEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSV
MMAR_3744|M.marinum_M GEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSV
MAV_1755|M.avium_104 GEKYDLMIAVVSALTLIFMIMLLLTRSVVAALVIVGTAASSIAASFGLSV
MSMEG_0576|M.smegmatis_MC2_155 GARYDLMIAVVSALTLIFMIMLILTRSAVAALVIVGTAASSIAASFGISV
* :**::* :::: ***:***::* : :** *****. *:.**.*:**
Mb0458c|M.bovis_AF2122/97 LLWQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGI
Rv0450c|M.tuberculosis_H37Rv LLWQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGI
MLBr_02378|M.leprae_Br4923 LLWQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGI
TH_3260|M.thermoresistible__bu LIWQYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGM
Mvan_3189|M.vanbaalenii_PYR-1 LFWQHILGTELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGI
Mflv_4418|M.gilvum_PYR-GCK LLWQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGI
MAB_3150|M.abscessus_ATCC_1997 LIWQDLLGMDLHWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGF
MUL_3688|M.ulcerans_Agy99 LIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGI
MMAR_3744|M.marinum_M LIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGI
MAV_1755|M.avium_104 LIWQDLFGIRIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHGGLKTGI
MSMEG_0576|M.smegmatis_MC2_155 LLWQDLFGVEVHWLVMLMSVIILLAVGSDYNLLLVSRFKDEIHAGLKTGI
*:** :.. :*::* :::*:*****:*****:::*:::*: .*: **:
Mb0458c|M.bovis_AF2122/97 IRSMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLI
Rv0450c|M.tuberculosis_H37Rv IRSMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLI
MLBr_02378|M.leprae_Br4923 IRSMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLI
TH_3260|M.thermoresistible__bu IRAMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFV
Mvan_3189|M.vanbaalenii_PYR-1 IRAMGGSGSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLV
Mflv_4418|M.gilvum_PYR-GCK IRAMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLI
MAB_3150|M.abscessus_ATCC_1997 IRAMGGSGKVVTNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLI
MUL_3688|M.ulcerans_Agy99 IRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLI
MMAR_3744|M.marinum_M IRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLI
MAV_1755|M.avium_104 IRSMAGTGGVVTAAGLVFAFTMAAMLGSELRVLGQFGSTVCIGLLLDTLI
MSMEG_0576|M.smegmatis_MC2_155 IRSMAGTGGVVTSAGLVFAATMAAMLGSELVVLAQMGSTIAIGLLLDTLI
**:*.*:* *** *****. ** : *:* ::.*.*:*: :***:**::
Mb0458c|M.bovis_AF2122/97 VRSFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDR
Rv0450c|M.tuberculosis_H37Rv VRSFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDR
MLBr_02378|M.leprae_Br4923 VRSFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD--
TH_3260|M.thermoresistible__bu VRSFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV--
Mvan_3189|M.vanbaalenii_PYR-1 IRAFMTPSIAALLGPWFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV--
Mflv_4418|M.gilvum_PYR-GCK VRSFMTPAVAALLGRWFWWPQKFRSAASERRLARIG-VQPATAGR-----
MAB_3150|M.abscessus_ATCC_1997 VRSFMMPSIAALLGRWFWWPLRVRTHGTAGV-------------------
MUL_3688|M.ulcerans_Agy99 VRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH-----------
MMAR_3744|M.marinum_M VRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH-----------
MAV_1755|M.avium_104 VRTLLMPSIATLLGRWFWWPMVVHPRGDNARRPVPASS------------
MSMEG_0576|M.smegmatis_MC2_155 VRSLLMPSIATLLGRWFWWPQVVYPRGDNHFRRPTAVSRGTGDEDTAALP
:*::: *::*:*** *****
Mb0458c|M.bovis_AF2122/97 LG-
Rv0450c|M.tuberculosis_H37Rv LG-
MLBr_02378|M.leprae_Br4923 ---
TH_3260|M.thermoresistible__bu ---
Mvan_3189|M.vanbaalenii_PYR-1 ---
Mflv_4418|M.gilvum_PYR-GCK ---
MAB_3150|M.abscessus_ATCC_1997 ---
MUL_3688|M.ulcerans_Agy99 ---
MMAR_3744|M.marinum_M ---
MAV_1755|M.avium_104 ---
MSMEG_0576|M.smegmatis_MC2_155 VPS