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ADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFD SDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQVYLQGN QGEPRANEAVAAVREIVDRTPAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSV ATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRE TAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFGL FDPKRAISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQH FGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTT QRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDF FRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRS MQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVR FIISHEGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLI FVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSR FKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP AVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4418 | - | - | 100% (948) | transport protein |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 69.84% (925) | transport protein |
M. gilvum PYR-GCK | Mflv_4825 | - | 0.0 | 62.36% (922) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0695c | mmpL5 | 0.0 | 67.39% (926) | transmembrane transport protein MmpL5 |
M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 66.42% (944) | transmembrane transport protein MmpL5 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.79% (935) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4382c | - | 0.0 | 62.96% (926) | putative membrane protein, MmpL |
M. marinum M | MMAR_0775 | - | 0.0 | 66.31% (941) | MmpL family transport protein |
M. avium 104 | MAV_2510 | - | 0.0 | 65.34% (929) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 67.03% (922) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 62.30% (931) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 66.67% (924) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 92.12% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4418|M.gilvum_PYR-GCK ----------MADAGRSG-----------------------------IGR Mvan_1936|M.vanbaalenii_PYR-1 ----------MADAGRSG-----------------------------IGR Mb0695c|M.bovis_AF2122/97 ------MIVQRTAAPTGSVPPD------------RHAARP------FIPR Rv0676c|M.tuberculosis_H37Rv ------MIVQRTAAPTGSVPPD------------RHAARP------FIPR MUL_0757|M.ulcerans_Agy99 ------MTATTTDTPTDVVPPA------------EHPPRP------FIPR TH_3260|M.thermoresistible__bu ------MTANPGHVRTDEAPTD------------RLDIKVSTHGPSFIST MAV_2510|M.avium_104 ------MSTTFDDTRTDAIPVV------------KEPVRE------KIPR MSMEG_3496|M.smegmatis_MC2_155 ------MSNPSHDAPTDAMGVSG----------PKHARPG------GIAK MAB_4382c|M.abscessus_ATCC_199 ------MSKPMNDPTTDAFPAA------------RHAARP------WLPR MLBr_02378|M.leprae_Br4923 ------MTVKCAN------------------DLDTHTKPP------FVAR MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRP------SMAR : Mflv_4418|M.gilvum_PYR-GCK IIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMK Mvan_1936|M.vanbaalenii_PYR-1 IIHLLAVPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSME Mb0695c|M.bovis_AF2122/97 MIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMK Rv0676c|M.tuberculosis_H37Rv MIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMK MUL_0757|M.ulcerans_Agy99 MIRTFAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMK TH_3260|M.thermoresistible__bu WIRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMK MAV_2510|M.avium_104 FIRAFAVPIIIGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATK MSMEG_3496|M.smegmatis_MC2_155 WIRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMK MAB_4382c|M.abscessus_ATCC_199 MIRVLAVPIVLGWIAVTIALNTVVPQLEEVGHMRAVSMSPNDAPAMIATK MLBr_02378|M.leprae_Br4923 MIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQ MMAR_0775|M.marinum_M LIHRMAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMK *: :::*::: *: :*.*: **. ::* ::. * : :: : Mflv_4418|M.gilvum_PYR-GCK RVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHI Mvan_1936|M.vanbaalenii_PYR-1 RVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHV Mb0695c|M.bovis_AF2122/97 HIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSL Rv0676c|M.tuberculosis_H37Rv HIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSL MUL_0757|M.ulcerans_Agy99 HIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSV TH_3260|M.thermoresistible__bu RVGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENV MAV_2510|M.avium_104 RMGAVFNEYKSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHV MSMEG_3496|M.smegmatis_MC2_155 RVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHV MAB_4382c|M.abscessus_ATCC_199 RVGEVFEEFKTSSSVMIVLEGEQSLGADAHRFYDQMVRDLRADTTHVQHV MLBr_02378|M.leprae_Br4923 KMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSV MMAR_0775|M.marinum_M RVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHV ::* * * .:.* *:****:..** *: :** :: *.** :*: : Mflv_4418|M.gilvum_PYR-GCK ADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT Mvan_1936|M.vanbaalenii_PYR-1 ADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT Mb0695c|M.bovis_AF2122/97 QDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL Rv0676c|M.tuberculosis_H37Rv QDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL MUL_0757|M.ulcerans_Agy99 QDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL TH_3260|M.thermoresistible__bu QDLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATV MAV_2510|M.avium_104 QDMWSDPLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSV MSMEG_3496|M.smegmatis_MC2_155 QDFWGDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESV MAB_4382c|M.abscessus_ATCC_199 QDFWADALTAAAAQSSDGKAAYVQVYIAGDQGEALANESVEAVRHITAAV MLBr_02378|M.leprae_Br4923 QDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT MMAR_0775|M.marinum_M QDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDT *:*.*.**... ** ** ::*** *:*** *:*:: :*: : Mflv_4418|M.gilvum_PYR-GCK ---PAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVF Mvan_1936|M.vanbaalenii_PYR-1 ---PAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVF Mb0695c|M.bovis_AF2122/97 ---APPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVY Rv0676c|M.tuberculosis_H37Rv ---APPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVY MUL_0757|M.ulcerans_Agy99 ---QAPPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVY TH_3260|M.thermoresistible__bu SEEMAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVY MAV_2510|M.avium_104 ---QAPNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVY MSMEG_3496|M.smegmatis_MC2_155 ---PAPPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVY MAB_4382c|M.abscessus_ATCC_199 ---PPSPGVRVYVTGPATTSADQEIVANDSMELIELVTFGVIMVMLLLVY MLBr_02378|M.leprae_Br4923 ---PAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVY MMAR_0775|M.marinum_M ---PAPPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVY .. *: .:*** :. ** .: *: : :. ** ** *: Mflv_4418|M.gilvum_PYR-GCK RSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAA Mvan_1936|M.vanbaalenii_PYR-1 RSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAA Mb0695c|M.bovis_AF2122/97 RSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAA Rv0676c|M.tuberculosis_H37Rv RSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAA MUL_0757|M.ulcerans_Agy99 RSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAA TH_3260|M.thermoresistible__bu RSVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAI MAV_2510|M.avium_104 RSVITVLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAA MSMEG_3496|M.smegmatis_MC2_155 RSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAA MAB_4382c|M.abscessus_ATCC_199 RSVITMVIVVAMVMLELASARGLVALLSYHNAFGLTSFATSLVVTLAIAA MLBr_02378|M.leprae_Br4923 RSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAA MMAR_0775|M.marinum_M RSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAA **. * : * :** :*:*. :**: **..*:. :.** Mflv_4418|M.gilvum_PYR-GCK GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC Mvan_1936|M.vanbaalenii_PYR-1 GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC Mb0695c|M.bovis_AF2122/97 ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC Rv0676c|M.tuberculosis_H37Rv ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC MUL_0757|M.ulcerans_Agy99 ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC TH_3260|M.thermoresistible__bu AVDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFC MAV_2510|M.avium_104 ATDYAIFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFC MSMEG_3496|M.smegmatis_MC2_155 ATDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLC MAB_4382c|M.abscessus_ATCC_199 ATDYAIFLIGRYQEARRAGEDRESAYYTMFHGTAHVVLASGLTIAGATFC MLBr_02378|M.leprae_Br4923 GTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFC MMAR_0775|M.marinum_M GTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYC ..**.** ******* . .: :::**: .* **: .**:**:** * Mflv_4418|M.gilvum_PYR-GCK LSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRA Mvan_1936|M.vanbaalenii_PYR-1 LSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRA Mb0695c|M.bovis_AF2122/97 LSFTRLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRM Rv0676c|M.tuberculosis_H37Rv LSFTRLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRM MUL_0757|M.ulcerans_Agy99 LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM TH_3260|M.thermoresistible__bu LSFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRA MAV_2510|M.avium_104 LHFTNLPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRT MSMEG_3496|M.smegmatis_MC2_155 LHFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRA MAB_4382c|M.abscessus_ATCC_199 LHFTRLPYFKTTGIPLSIGMAIVVAMALTLGPALISVASRFGNVLEPKGA MLBr_02378|M.leprae_Br4923 LSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRL MMAR_0775|M.marinum_M LSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRK * *:.:***:: * * ::* : : :**:*.*:: : : * ::*: Mflv_4418|M.gilvum_PYR-GCK ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE Mvan_1936|M.vanbaalenii_PYR-1 ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE Mb0695c|M.bovis_AF2122/97 ARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPA Rv0676c|M.tuberculosis_H37Rv ARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPA MUL_0757|M.ulcerans_Agy99 ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA TH_3260|M.thermoresistible__bu ARVRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPA MAV_2510|M.avium_104 QRIRGWRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPT MSMEG_3496|M.smegmatis_MC2_155 MRTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQ MAB_4382c|M.abscessus_ATCC_199 GKARGWRRVGAATVRWPGAILVAAVTMALVGLLTLPGYHTTYNDRIYLPG MLBr_02378|M.leprae_Br4923 IKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA MMAR_0775|M.marinum_M MRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPA * **::*. **** .:: : ::::**::****:*.*. : *** Mflv_4418|M.gilvum_PYR-GCK DIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVF Mvan_1936|M.vanbaalenii_PYR-1 DVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIF Mb0695c|M.bovis_AF2122/97 DLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIF Rv0676c|M.tuberculosis_H37Rv DLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIF MUL_0757|M.ulcerans_Agy99 DLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIF TH_3260|M.thermoresistible__bu SFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVF MAV_2510|M.avium_104 DLPANEGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVF MSMEG_3496|M.smegmatis_MC2_155 DLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVF MAB_4382c|M.abscessus_ATCC_199 QVPANVGYAAADRHFSKAKMNPDLLLVESDHDLRNPADFLVIDKIAKALA MLBr_02378|M.leprae_Br4923 SIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIF MMAR_0775|M.marinum_M STPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVF . *:* *: .*::** *:::*::*::*:***:**.:*:*:::::*: : Mflv_4418|M.gilvum_PYR-GCK RVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADML Mvan_1936|M.vanbaalenii_PYR-1 RVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADML Mb0695c|M.bovis_AF2122/97 AVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARML Rv0676c|M.tuberculosis_H37Rv AVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARML MUL_0757|M.ulcerans_Agy99 GVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSML TH_3260|M.thermoresistible__bu QVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADML MAV_2510|M.avium_104 RVPGIGRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADML MSMEG_3496|M.smegmatis_MC2_155 QVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADML MAB_4382c|M.abscessus_ATCC_199 RVRGIAQVQTITRPDGKPIKHTSIPFNMSTANTAQTLTNDYSQANFANLL MLBr_02378|M.leprae_Br4923 RVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLL MMAR_0775|M.marinum_M HLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADML : *:.:** :*** *..:.*::*** :* .. . . .* : :* Mflv_4418|M.gilvum_PYR-GCK VQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLAD Mvan_1936|M.vanbaalenii_PYR-1 VQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLAN Mb0695c|M.bovis_AF2122/97 EQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIAD Rv0676c|M.tuberculosis_H37Rv EQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIAD MUL_0757|M.ulcerans_Agy99 QQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIAD TH_3260|M.thermoresistible__bu VQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISE MAV_2510|M.avium_104 HQADMMQTTIDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMAD MSMEG_3496|M.smegmatis_MC2_155 VMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIAD MAB_4382c|M.abscessus_ATCC_199 KQADAMQVTIDSMEKMQAITQQMAEVTASMSANMKNTAQDINQLRDNMSN MLBr_02378|M.leprae_Br4923 RQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIAN MMAR_0775|M.marinum_M IQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIAD . : : : .* : : : .:*: ::: Mflv_4418|M.gilvum_PYR-GCK FDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPD Mvan_1936|M.vanbaalenii_PYR-1 LDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPD Mb0695c|M.bovis_AF2122/97 FDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPL Rv0676c|M.tuberculosis_H37Rv FDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPL MUL_0757|M.ulcerans_Agy99 FDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPL TH_3260|M.thermoresistible__bu FDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPH MAV_2510|M.avium_104 FEDFFRPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPI MSMEG_3496|M.smegmatis_MC2_155 FDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPD MAB_4382c|M.abscessus_ATCC_199 FDDQFRPIRNYFYWEKHCFDIPMCWALRSVFDALDGISLMSDDFDTLVPD MLBr_02378|M.leprae_Br4923 FDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGD MMAR_0775|M.marinum_M FDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRD ::* **:*.***** ** .:*:* ::**:**:***:. : : : : Mflv_4418|M.gilvum_PYR-GCK LERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDA Mvan_1936|M.vanbaalenii_PYR-1 LERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDA Mb0695c|M.bovis_AF2122/97 MQRLDTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDS Rv0676c|M.tuberculosis_H37Rv MQRLDTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDS MUL_0757|M.ulcerans_Agy99 MERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDS TH_3260|M.thermoresistible__bu MHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENA MAV_2510|M.avium_104 MDHLDTLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNS MSMEG_3496|M.smegmatis_MC2_155 MDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQ MAB_4382c|M.abscessus_ATCC_199 IQRMAGLMPQMVVLMPPMIASMKEQKQIMLSQYQVQKAQQDQTMAMQANA MLBr_02378|M.leprae_Br4923 IKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNA MMAR_0775|M.marinum_M MDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNS :..: ****: :* : .*. : :* . ** : Mflv_4418|M.gilvum_PYR-GCK DAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHE Mvan_1936|M.vanbaalenii_PYR-1 DAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHE Mb0695c|M.bovis_AF2122/97 AAMGEAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHE Rv0676c|M.tuberculosis_H37Rv AAMGEAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHE MUL_0757|M.ulcerans_Agy99 SAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHE TH_3260|M.thermoresistible__bu NAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQ MAV_2510|M.avium_104 NAMGKAFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHD MSMEG_3496|M.smegmatis_MC2_155 TAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHE MAB_4382c|M.abscessus_ATCC_199 SAMGQAFDDAKNDDSFYLPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQ MLBr_02378|M.leprae_Br4923 NTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHR MMAR_0775|M.marinum_M TAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHE :**:*** : ******:***.*.. :*: .:: *:*.:*::.** * * Mflv_4418|M.gilvum_PYR-GCK GDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAF Mvan_1936|M.vanbaalenii_PYR-1 GDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGAN Mb0695c|M.bovis_AF2122/97 GDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNT Rv0676c|M.tuberculosis_H37Rv GDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNT MUL_0757|M.ulcerans_Agy99 GDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNT TH_3260|M.thermoresistible__bu GDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTK MAV_2510|M.avium_104 GDPMTQEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNN MSMEG_3496|M.smegmatis_MC2_155 GDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGAN MAB_4382c|M.abscessus_ATCC_199 SDPLTEEGTSRVEPLKTAAEDAIKGTPLEGSSIYVGGSAALYKDMQEGAD MLBr_02378|M.leprae_Br4923 GDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGAN MMAR_0775|M.marinum_M GDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSR .** : * : : * :*:******.: :*:.*:.: :**: :* Mflv_4418|M.gilvum_PYR-GCK YDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLW Mvan_1936|M.vanbaalenii_PYR-1 YDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLW Mb0695c|M.bovis_AF2122/97 YDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIW Rv0676c|M.tuberculosis_H37Rv YDLMIAGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIW MUL_0757|M.ulcerans_Agy99 FDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIW TH_3260|M.thermoresistible__bu YDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIW MAV_2510|M.avium_104 YDLLIAGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIW MSMEG_3496|M.smegmatis_MC2_155 YDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIW MAB_4382c|M.abscessus_ATCC_199 YDLLIAAVAALILIFLIMVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLW MLBr_02378|M.leprae_Br4923 WDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLW MMAR_0775|M.marinum_M WDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVW :**:**.:::: **::**:: **..**:.****** :**.****:***:* Mflv_4418|M.gilvum_PYR-GCK QHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRA Mvan_1936|M.vanbaalenii_PYR-1 QHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRS Mb0695c|M.bovis_AF2122/97 QHILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA Rv0676c|M.tuberculosis_H37Rv QHILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA MUL_0757|M.ulcerans_Agy99 QHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA TH_3260|M.thermoresistible__bu QYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRA MAV_2510|M.avium_104 QHLIGIELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRS MSMEG_3496|M.smegmatis_MC2_155 QHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRS MAB_4382c|M.abscessus_ATCC_199 QHIIGTPLHWMVLPMAVIILLAVGADYNLLLVSRMKEELHAGLHTGTIRS MLBr_02378|M.leprae_Br4923 QHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRS MMAR_0775|M.marinum_M QDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRA * :.* :*::*:.*::*:*****:*****:*:*:::*: .*::** **: Mflv_4418|M.gilvum_PYR-GCK MAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRS Mvan_1936|M.vanbaalenii_PYR-1 MAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRS Mb0695c|M.bovis_AF2122/97 MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS Rv0676c|M.tuberculosis_H37Rv MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS MUL_0757|M.ulcerans_Agy99 MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS TH_3260|M.thermoresistible__bu MGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRS MAV_2510|M.avium_104 MGGTGSVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRS MSMEG_3496|M.smegmatis_MC2_155 MGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRS MAB_4382c|M.abscessus_ATCC_199 MAGTGSVVTSAGLVFAFTMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRS MLBr_02378|M.leprae_Br4923 MGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRS MMAR_0775|M.marinum_M MAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRS *.*:* *** *****. ** : .*.: *:.*:****.:******:::** Mflv_4418|M.gilvum_PYR-GCK FMTPAVAALLGRWFWWPQKFRSAASERRLARIG----------------- Mvan_1936|M.vanbaalenii_PYR-1 FMTPAVAALLGRWFWWPQKVRSHASQRRLAALN----------------- Mb0695c|M.bovis_AF2122/97 FMTPSIAALLGKWFWWPQVVRQRPVPQPWPSPA----------------- Rv0676c|M.tuberculosis_H37Rv FMTPSIAALLGKWFWWPQVVRQRPIPQPWPSPA----------------- MUL_0757|M.ulcerans_Agy99 FMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPA----------------- TH_3260|M.thermoresistible__bu FMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVP----------------- MAV_2510|M.avium_104 LMTPSIAALLGKWFWWPQRVRQRPVPSPWPKPA----------------- MSMEG_3496|M.smegmatis_MC2_155 FMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPV----------------- MAB_4382c|M.abscessus_ATCC_199 FMTPSIASLLGRWFWWPMVVRPRPRPQPWPQPL----------------- MLBr_02378|M.leprae_Br4923 FMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG---------LP------ MMAR_0775|M.marinum_M FMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSA :* *::*:*:*:***** * . Mflv_4418|M.gilvum_PYR-GCK -------VQPATAGR---- Mvan_1936|M.vanbaalenii_PYR-1 -------H----------- Mb0695c|M.bovis_AF2122/97 -------SARTFALV---- Rv0676c|M.tuberculosis_H37Rv -------SARTFALV---- MUL_0757|M.ulcerans_Agy99 -------PTPPPATTSV-- TH_3260|M.thermoresistible__bu -------PRGPATTDRVSV MAV_2510|M.avium_104 -------AQEREVLADA-- MSMEG_3496|M.smegmatis_MC2_155 -------QRDPEDALNRV- MAB_4382c|M.abscessus_ATCC_199 -------HAGAAEAVRA-- MLBr_02378|M.leprae_Br4923 -------PDRSLVYSD--- MMAR_0775|M.marinum_M DGPEDTNTERLAVSSPHY-