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M. gilvum PYR-GCK Mflv_4418 (-)

annotation: transport protein
coordinates: 4697006 - 4699852
length: 948

ADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFD
SDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQVYLQGN
QGEPRANEAVAAVREIVDRTPAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSV
ATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRE
TAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFGL
FDPKRAISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQH
FGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTT
QRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDF
FRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRS
MQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVR
FIISHEGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLI
FVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSR
FKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP
AVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4418--100% (948)transport protein
M. gilvum PYR-GCKMflv_3435-0.069.84% (925) transport protein
M. gilvum PYR-GCKMflv_4825-0.062.36% (922) transport protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0695cmmpL50.067.39% (926) transmembrane transport protein MmpL5
M. tuberculosis H37RvRv0676cmmpL50.066.42% (944) transmembrane transport protein MmpL5
M. leprae Br4923MLBr_02378-0.059.79% (935) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_4382c-0.062.96% (926) putative membrane protein, MmpL
M. marinum MMMAR_0775-0.066.31% (941) MmpL family transport protein
M. avium 104MAV_2510-0.065.34% (929) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.067.03% (922) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.062.30% (931) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.066.67% (924) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.092.12% (939) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ----------MADAGRSG-----------------------------IGR
Mvan_1936|M.vanbaalenii_PYR-1       ----------MADAGRSG-----------------------------IGR
Mb0695c|M.bovis_AF2122/97           ------MIVQRTAAPTGSVPPD------------RHAARP------FIPR
Rv0676c|M.tuberculosis_H37Rv        ------MIVQRTAAPTGSVPPD------------RHAARP------FIPR
MUL_0757|M.ulcerans_Agy99           ------MTATTTDTPTDVVPPA------------EHPPRP------FIPR
TH_3260|M.thermoresistible__bu      ------MTANPGHVRTDEAPTD------------RLDIKVSTHGPSFIST
MAV_2510|M.avium_104                ------MSTTFDDTRTDAIPVV------------KEPVRE------KIPR
MSMEG_3496|M.smegmatis_MC2_155      ------MSNPSHDAPTDAMGVSG----------PKHARPG------GIAK
MAB_4382c|M.abscessus_ATCC_199      ------MSKPMNDPTTDAFPAA------------RHAARP------WLPR
MLBr_02378|M.leprae_Br4923          ------MTVKCAN------------------DLDTHTKPP------FVAR
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRP------SMAR
                                                                                   :  

Mflv_4418|M.gilvum_PYR-GCK          IIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMK
Mvan_1936|M.vanbaalenii_PYR-1       IIHLLAVPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSME
Mb0695c|M.bovis_AF2122/97           MIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMK
Rv0676c|M.tuberculosis_H37Rv        MIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMK
MUL_0757|M.ulcerans_Agy99           MIRTFAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMK
TH_3260|M.thermoresistible__bu      WIRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMK
MAV_2510|M.avium_104                FIRAFAVPIIIGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATK
MSMEG_3496|M.smegmatis_MC2_155      WIRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMK
MAB_4382c|M.abscessus_ATCC_199      MIRVLAVPIVLGWIAVTIALNTVVPQLEEVGHMRAVSMSPNDAPAMIATK
MLBr_02378|M.leprae_Br4923          MIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQ
MMAR_0775|M.marinum_M               LIHRMAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMK
                                     *: :::*::: *:         :*.*: **. ::* ::.  * : :: :

Mflv_4418|M.gilvum_PYR-GCK          RVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHI
Mvan_1936|M.vanbaalenii_PYR-1       RVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHV
Mb0695c|M.bovis_AF2122/97           HIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSL
Rv0676c|M.tuberculosis_H37Rv        HIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSL
MUL_0757|M.ulcerans_Agy99           HIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSV
TH_3260|M.thermoresistible__bu      RVGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENV
MAV_2510|M.avium_104                RMGAVFNEYKSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHV
MSMEG_3496|M.smegmatis_MC2_155      RVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHV
MAB_4382c|M.abscessus_ATCC_199      RVGEVFEEFKTSSSVMIVLEGEQSLGADAHRFYDQMVRDLRADTTHVQHV
MLBr_02378|M.leprae_Br4923          KMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSV
MMAR_0775|M.marinum_M               RVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHV
                                    ::*  * * .:.*  *:****:..**  *: :** ::  *.**  :*: :

Mflv_4418|M.gilvum_PYR-GCK          ADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT
Mvan_1936|M.vanbaalenii_PYR-1       ADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT
Mb0695c|M.bovis_AF2122/97           QDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL
Rv0676c|M.tuberculosis_H37Rv        QDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL
MUL_0757|M.ulcerans_Agy99           QDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL
TH_3260|M.thermoresistible__bu      QDLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATV
MAV_2510|M.avium_104                QDMWSDPLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSV
MSMEG_3496|M.smegmatis_MC2_155      QDFWGDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESV
MAB_4382c|M.abscessus_ATCC_199      QDFWADALTAAAAQSSDGKAAYVQVYIAGDQGEALANESVEAVRHITAAV
MLBr_02378|M.leprae_Br4923          QDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT
MMAR_0775|M.marinum_M               QDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDT
                                     *:*.*.**... ** ** ::***    *:***  *:*:: :*: :    

Mflv_4418|M.gilvum_PYR-GCK          ---PAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVF
Mvan_1936|M.vanbaalenii_PYR-1       ---PAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVF
Mb0695c|M.bovis_AF2122/97           ---APPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVY
Rv0676c|M.tuberculosis_H37Rv        ---APPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVY
MUL_0757|M.ulcerans_Agy99           ---QAPPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVY
TH_3260|M.thermoresistible__bu      SEEMAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVY
MAV_2510|M.avium_104                ---QAPNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVY
MSMEG_3496|M.smegmatis_MC2_155      ---PAPPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVY
MAB_4382c|M.abscessus_ATCC_199      ---PPSPGVRVYVTGPATTSADQEIVANDSMELIELVTFGVIMVMLLLVY
MLBr_02378|M.leprae_Br4923          ---PAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVY
MMAR_0775|M.marinum_M               ---PAPPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVY
                                        .. *: .:*** :.  **    .: *:  :   :. **   ** *:

Mflv_4418|M.gilvum_PYR-GCK          RSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAA
Mvan_1936|M.vanbaalenii_PYR-1       RSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAA
Mb0695c|M.bovis_AF2122/97           RSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAA
Rv0676c|M.tuberculosis_H37Rv        RSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAA
MUL_0757|M.ulcerans_Agy99           RSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAA
TH_3260|M.thermoresistible__bu      RSVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAI
MAV_2510|M.avium_104                RSVITVLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAA
MSMEG_3496|M.smegmatis_MC2_155      RSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAA
MAB_4382c|M.abscessus_ATCC_199      RSVITMVIVVAMVMLELASARGLVALLSYHNAFGLTSFATSLVVTLAIAA
MLBr_02378|M.leprae_Br4923          RSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAA
MMAR_0775|M.marinum_M               RSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAA
                                    **. *    :  *      :** :*:*.    :**: **..*:. :.** 

Mflv_4418|M.gilvum_PYR-GCK          GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC
Mvan_1936|M.vanbaalenii_PYR-1       GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC
Mb0695c|M.bovis_AF2122/97           ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC
Rv0676c|M.tuberculosis_H37Rv        ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC
MUL_0757|M.ulcerans_Agy99           ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC
TH_3260|M.thermoresistible__bu      AVDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFC
MAV_2510|M.avium_104                ATDYAIFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFC
MSMEG_3496|M.smegmatis_MC2_155      ATDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLC
MAB_4382c|M.abscessus_ATCC_199      ATDYAIFLIGRYQEARRAGEDRESAYYTMFHGTAHVVLASGLTIAGATFC
MLBr_02378|M.leprae_Br4923          GTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFC
MMAR_0775|M.marinum_M               GTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYC
                                    ..**.**  *******  . .:  :::**: .* **: .**:**:**  *

Mflv_4418|M.gilvum_PYR-GCK          LSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRA
Mvan_1936|M.vanbaalenii_PYR-1       LSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRA
Mb0695c|M.bovis_AF2122/97           LSFTRLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRM
Rv0676c|M.tuberculosis_H37Rv        LSFTRLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRM
MUL_0757|M.ulcerans_Agy99           LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM
TH_3260|M.thermoresistible__bu      LSFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRA
MAV_2510|M.avium_104                LHFTNLPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRT
MSMEG_3496|M.smegmatis_MC2_155      LHFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRA
MAB_4382c|M.abscessus_ATCC_199      LHFTRLPYFKTTGIPLSIGMAIVVAMALTLGPALISVASRFGNVLEPKGA
MLBr_02378|M.leprae_Br4923          LSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRL
MMAR_0775|M.marinum_M               LSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRK
                                    * *:.:***:: * * ::*  : :  :**:*.*:: : : *   ::*:  

Mflv_4418|M.gilvum_PYR-GCK          ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE
Mvan_1936|M.vanbaalenii_PYR-1       ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE
Mb0695c|M.bovis_AF2122/97           ARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPA
Rv0676c|M.tuberculosis_H37Rv        ARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPA
MUL_0757|M.ulcerans_Agy99           ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA
TH_3260|M.thermoresistible__bu      ARVRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPA
MAV_2510|M.avium_104                QRIRGWRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPT
MSMEG_3496|M.smegmatis_MC2_155      MRTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQ
MAB_4382c|M.abscessus_ATCC_199      GKARGWRRVGAATVRWPGAILVAAVTMALVGLLTLPGYHTTYNDRIYLPG
MLBr_02378|M.leprae_Br4923          IKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA
MMAR_0775|M.marinum_M               MRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPA
                                       * **::*.  **** .::  :  ::::**::****:*.*. : *** 

Mflv_4418|M.gilvum_PYR-GCK          DIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVF
Mvan_1936|M.vanbaalenii_PYR-1       DVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIF
Mb0695c|M.bovis_AF2122/97           DLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIF
Rv0676c|M.tuberculosis_H37Rv        DLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIF
MUL_0757|M.ulcerans_Agy99           DLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIF
TH_3260|M.thermoresistible__bu      SFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVF
MAV_2510|M.avium_104                DLPANEGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVF
MSMEG_3496|M.smegmatis_MC2_155      DLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVF
MAB_4382c|M.abscessus_ATCC_199      QVPANVGYAAADRHFSKAKMNPDLLLVESDHDLRNPADFLVIDKIAKALA
MLBr_02378|M.leprae_Br4923          SIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIF
MMAR_0775|M.marinum_M               STPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVF
                                    . *:* *: .*::**  *:::*::*::*:***:**.:*:*:::::*: : 

Mflv_4418|M.gilvum_PYR-GCK          RVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADML
Mvan_1936|M.vanbaalenii_PYR-1       RVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADML
Mb0695c|M.bovis_AF2122/97           AVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARML
Rv0676c|M.tuberculosis_H37Rv        AVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARML
MUL_0757|M.ulcerans_Agy99           GVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSML
TH_3260|M.thermoresistible__bu      QVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADML
MAV_2510|M.avium_104                RVPGIGRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADML
MSMEG_3496|M.smegmatis_MC2_155      QVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADML
MAB_4382c|M.abscessus_ATCC_199      RVRGIAQVQTITRPDGKPIKHTSIPFNMSTANTAQTLTNDYSQANFANLL
MLBr_02378|M.leprae_Br4923          RVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLL
MMAR_0775|M.marinum_M               HLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADML
                                     : *:.:** :*** *..:.*::*** :*  .. .  . .* :     :*

Mflv_4418|M.gilvum_PYR-GCK          VQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLAD
Mvan_1936|M.vanbaalenii_PYR-1       VQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLAN
Mb0695c|M.bovis_AF2122/97           EQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIAD
Rv0676c|M.tuberculosis_H37Rv        EQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIAD
MUL_0757|M.ulcerans_Agy99           QQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIAD
TH_3260|M.thermoresistible__bu      VQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISE
MAV_2510|M.avium_104                HQADMMQTTIDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMAD
MSMEG_3496|M.smegmatis_MC2_155      VMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIAD
MAB_4382c|M.abscessus_ATCC_199      KQADAMQVTIDSMEKMQAITQQMAEVTASMSANMKNTAQDINQLRDNMSN
MLBr_02378|M.leprae_Br4923          RQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIAN
MMAR_0775|M.marinum_M               IQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIAD
                                      .  :   :  : .*  :   :      :            .:*: :::

Mflv_4418|M.gilvum_PYR-GCK          FDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPD
Mvan_1936|M.vanbaalenii_PYR-1       LDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPD
Mb0695c|M.bovis_AF2122/97           FDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPL
Rv0676c|M.tuberculosis_H37Rv        FDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPL
MUL_0757|M.ulcerans_Agy99           FDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPL
TH_3260|M.thermoresistible__bu      FDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPH
MAV_2510|M.avium_104                FEDFFRPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPI
MSMEG_3496|M.smegmatis_MC2_155      FDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPD
MAB_4382c|M.abscessus_ATCC_199      FDDQFRPIRNYFYWEKHCFDIPMCWALRSVFDALDGISLMSDDFDTLVPD
MLBr_02378|M.leprae_Br4923          FDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGD
MMAR_0775|M.marinum_M               FDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRD
                                    ::*  **:*.***** ** .:*:* ::**:**:***:. : : :  :   

Mflv_4418|M.gilvum_PYR-GCK          LERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDA
Mvan_1936|M.vanbaalenii_PYR-1       LERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDA
Mb0695c|M.bovis_AF2122/97           MQRLDTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDS
Rv0676c|M.tuberculosis_H37Rv        MQRLDTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDS
MUL_0757|M.ulcerans_Agy99           MERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDS
TH_3260|M.thermoresistible__bu      MHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENA
MAV_2510|M.avium_104                MDHLDTLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNS
MSMEG_3496|M.smegmatis_MC2_155      MDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQ
MAB_4382c|M.abscessus_ATCC_199      IQRMAGLMPQMVVLMPPMIASMKEQKQIMLSQYQVQKAQQDQTMAMQANA
MLBr_02378|M.leprae_Br4923          IKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNA
MMAR_0775|M.marinum_M               MDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNS
                                    :..:  ****:   :*  : .*.  :  :*       .  **      : 

Mflv_4418|M.gilvum_PYR-GCK          DAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHE
Mvan_1936|M.vanbaalenii_PYR-1       DAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHE
Mb0695c|M.bovis_AF2122/97           AAMGEAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHE
Rv0676c|M.tuberculosis_H37Rv        AAMGEAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHE
MUL_0757|M.ulcerans_Agy99           SAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHE
TH_3260|M.thermoresistible__bu      NAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQ
MAV_2510|M.avium_104                NAMGKAFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHD
MSMEG_3496|M.smegmatis_MC2_155      TAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHE
MAB_4382c|M.abscessus_ATCC_199      SAMGQAFDDAKNDDSFYLPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQ
MLBr_02378|M.leprae_Br4923          NTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHR
MMAR_0775|M.marinum_M               TAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHE
                                     :**:*** : ******:***.*.. :*: .:: *:*.:*::.** * * 

Mflv_4418|M.gilvum_PYR-GCK          GDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAF
Mvan_1936|M.vanbaalenii_PYR-1       GDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGAN
Mb0695c|M.bovis_AF2122/97           GDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNT
Rv0676c|M.tuberculosis_H37Rv        GDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNT
MUL_0757|M.ulcerans_Agy99           GDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNT
TH_3260|M.thermoresistible__bu      GDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTK
MAV_2510|M.avium_104                GDPMTQEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNN
MSMEG_3496|M.smegmatis_MC2_155      GDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGAN
MAB_4382c|M.abscessus_ATCC_199      SDPLTEEGTSRVEPLKTAAEDAIKGTPLEGSSIYVGGSAALYKDMQEGAD
MLBr_02378|M.leprae_Br4923          GDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGAN
MMAR_0775|M.marinum_M               GDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSR
                                    .** :  *   :  :   * :*:******.: :*:.*:.: :**: :*  

Mflv_4418|M.gilvum_PYR-GCK          YDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLW
Mvan_1936|M.vanbaalenii_PYR-1       YDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLW
Mb0695c|M.bovis_AF2122/97           YDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIW
Rv0676c|M.tuberculosis_H37Rv        YDLMIAGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIW
MUL_0757|M.ulcerans_Agy99           FDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIW
TH_3260|M.thermoresistible__bu      YDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIW
MAV_2510|M.avium_104                YDLLIAGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIW
MSMEG_3496|M.smegmatis_MC2_155      YDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIW
MAB_4382c|M.abscessus_ATCC_199      YDLLIAAVAALILIFLIMVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLW
MLBr_02378|M.leprae_Br4923          WDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLW
MMAR_0775|M.marinum_M               WDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVW
                                    :**:**.:::: **::**:: **..**:.****** :**.****:***:*

Mflv_4418|M.gilvum_PYR-GCK          QHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRA
Mvan_1936|M.vanbaalenii_PYR-1       QHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRS
Mb0695c|M.bovis_AF2122/97           QHILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA
Rv0676c|M.tuberculosis_H37Rv        QHILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA
MUL_0757|M.ulcerans_Agy99           QHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRA
TH_3260|M.thermoresistible__bu      QYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRA
MAV_2510|M.avium_104                QHLIGIELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRS
MSMEG_3496|M.smegmatis_MC2_155      QHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRS
MAB_4382c|M.abscessus_ATCC_199      QHIIGTPLHWMVLPMAVIILLAVGADYNLLLVSRMKEELHAGLHTGTIRS
MLBr_02378|M.leprae_Br4923          QHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRS
MMAR_0775|M.marinum_M               QDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRA
                                    * :.*  :*::*:.*::*:*****:*****:*:*:::*: .*::** **:

Mflv_4418|M.gilvum_PYR-GCK          MAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRS
Mvan_1936|M.vanbaalenii_PYR-1       MAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRS
Mb0695c|M.bovis_AF2122/97           MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS
Rv0676c|M.tuberculosis_H37Rv        MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS
MUL_0757|M.ulcerans_Agy99           MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS
TH_3260|M.thermoresistible__bu      MGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRS
MAV_2510|M.avium_104                MGGTGSVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRS
MSMEG_3496|M.smegmatis_MC2_155      MGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRS
MAB_4382c|M.abscessus_ATCC_199      MAGTGSVVTSAGLVFAFTMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRS
MLBr_02378|M.leprae_Br4923          MGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRS
MMAR_0775|M.marinum_M               MAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRS
                                    *.*:* *** *****. **  : .*.: *:.*:****.:******:::**

Mflv_4418|M.gilvum_PYR-GCK          FMTPAVAALLGRWFWWPQKFRSAASERRLARIG-----------------
Mvan_1936|M.vanbaalenii_PYR-1       FMTPAVAALLGRWFWWPQKVRSHASQRRLAALN-----------------
Mb0695c|M.bovis_AF2122/97           FMTPSIAALLGKWFWWPQVVRQRPVPQPWPSPA-----------------
Rv0676c|M.tuberculosis_H37Rv        FMTPSIAALLGKWFWWPQVVRQRPIPQPWPSPA-----------------
MUL_0757|M.ulcerans_Agy99           FMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPA-----------------
TH_3260|M.thermoresistible__bu      FMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVP-----------------
MAV_2510|M.avium_104                LMTPSIAALLGKWFWWPQRVRQRPVPSPWPKPA-----------------
MSMEG_3496|M.smegmatis_MC2_155      FMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPV-----------------
MAB_4382c|M.abscessus_ATCC_199      FMTPSIASLLGRWFWWPMVVRPRPRPQPWPQPL-----------------
MLBr_02378|M.leprae_Br4923          FMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG---------LP------
MMAR_0775|M.marinum_M               FMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSA
                                    :* *::*:*:*:*****   *  .                          

Mflv_4418|M.gilvum_PYR-GCK          -------VQPATAGR----
Mvan_1936|M.vanbaalenii_PYR-1       -------H-----------
Mb0695c|M.bovis_AF2122/97           -------SARTFALV----
Rv0676c|M.tuberculosis_H37Rv        -------SARTFALV----
MUL_0757|M.ulcerans_Agy99           -------PTPPPATTSV--
TH_3260|M.thermoresistible__bu      -------PRGPATTDRVSV
MAV_2510|M.avium_104                -------AQEREVLADA--
MSMEG_3496|M.smegmatis_MC2_155      -------QRDPEDALNRV-
MAB_4382c|M.abscessus_ATCC_199      -------HAGAAEAVRA--
MLBr_02378|M.leprae_Br4923          -------PDRSLVYSD---
MMAR_0775|M.marinum_M               DGPEDTNTERLAVSSPHY-