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SEPVEAAPRVDQPLIPPFLPRMIHRLALPIVLVWLGIVFITNTVAPQLEVVAKTHSVSMSPTDAASFQSM MKVGATFKEFNSDNSAMILLEGDKPLGAEAHRYYDEIVRRVEQDKKHVQHVQDFWSDPLTAAGSQSHDQK AAYVQVYLAGNMGGGLANESALAVRKIVDSVPAPPGIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVI IVMLLVVYRSIITVAVMLGMVFIELAAARGVVATLGNYGVMGLSTFANNMLVLMAIAAGTDYAIFVVGRY HEARGLGETREQAFYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFQSLGVPCAVGMLVAVLAALTLAP AMLTVASFFKLMDPKRTLQTRGWRRMGTAVVRWPAPVLAVTIAVALVGLLALPGYKTDYDNRHFLPADTP ANVGYAAADRHFDQARLNPELLMIETDHDLRNPADFIVLDKVAKAVFHIPGIGRVQTITRPLGTPLDHST LGFQMGAQAAGRLQTQHYQEEQANNLLKQADELRKTMATLHEQMQVTQDLSNTTHETTRLTKETVQITER LRDDIANFDDFLRPIRSYFYWEKHCYDIPVCWALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVA LIPPQIESQQRNLDTIMSNYAITQGLNDQAKAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLK NFISPDGRAVRLIISHEGDPASPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDL LIAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYLLGLKLHWMVLAMAVILLLAV GSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMFSPLLVMAQVGTTIALGLLF DTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGPRRAVRELILADVDEHPPGGVVQPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4696 | - | - | 100% (976) | MmpL4 protein |
| M. avium 104 | MAV_3863 | - | 0.0 | 64.50% (938) | MmpL4 protein |
| M. avium 104 | MAV_2510 | - | 0.0 | 59.54% (959) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 0.0 | 65.62% (951) | transmembrane transport protein MmpL6 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 63.17% (934) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 61.38% (945) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.24% (947) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_0987c | - | 0.0 | 59.33% (932) | membrane protein MmpL |
| M. marinum M | MMAR_0775 | - | 0.0 | 65.36% (944) | MmpL family transport protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 61.38% (927) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 56.62% (929) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 59.40% (941) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 63.61% (926) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0450c|M.tuberculosis_H37Rv --------MSTKFAND----------------SNTNARPEKPFIARMIHA
MLBr_02378|M.leprae_Br4923 --------MTVKCAND----------------LDTHTKP--PFVARMIHR
MMAR_0775|M.marinum_M --MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHR
Mflv_4418|M.gilvum_PYR-GCK -----------------------------------MADAGRSGIGRIIRV
Mvan_1936|M.vanbaalenii_PYR-1 -----------------------------------MADAGRSGIGRIIHL
MSMEG_3496|M.smegmatis_MC2_155 -MSNP----SHDAPTD-------------AMGVSGPKHARPGGIAKWIRV
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTD-------------RLDIKVSTHG-PSFISTWIRR
MUL_0757|M.ulcerans_Agy99 MTATT-----TDTPTD-------------VVPP--AEHPPRPFIPRMIRT
Mb1583|M.bovis_AF2122/97 --------MSNHHRPRP-------------------------WLPHTIRR
MAB_0987c|M.abscessus_ATCC_199 --------MSANHAHES-------------------------RAAKIVRR
MAV_4696|M.avium_104 --------MSEPVEAAPR----------------VDQPLIPPFLPRMIHR
::
Rv0450c|M.tuberculosis_H37Rv FAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGM
MLBr_02378|M.leprae_Br4923 FAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQ
MMAR_0775|M.marinum_M MAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGK
Mflv_4418|M.gilvum_PYR-GCK LAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGA
Mvan_1936|M.vanbaalenii_PYR-1 LAVPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGA
MSMEG_3496|M.smegmatis_MC2_155 LAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGE
TH_3260|M.thermoresistible__bu LSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGE
MUL_0757|M.ulcerans_Agy99 FAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGK
Mb1583|M.bovis_AF2122/97 LSLPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGK
MAB_0987c|M.abscessus_ATCC_199 LAVPIVLFWVAIAAVTNATVPQLEVVGEERSAPLNAADAPSTLAMRHIGK
MAV_4696|M.avium_104 LALPIVLVWLGIVFITNTVAPQLEVVAKTHSVSMSPTDAASFQSMMKVGA
:::*::: *: : *.*: *.: : . .. * :* ::*
Rv0450c|M.tuberculosis_H37Rv VFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLW
MLBr_02378|M.leprae_Br4923 VFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFW
MMAR_0775|M.marinum_M VFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFW
Mflv_4418|M.gilvum_PYR-GCK NFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFW
Mvan_1936|M.vanbaalenii_PYR-1 NFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFW
MSMEG_3496|M.smegmatis_MC2_155 VFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFW
TH_3260|M.thermoresistible__bu LFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLW
MUL_0757|M.ulcerans_Agy99 VFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFW
Mb1583|M.bovis_AF2122/97 VFHEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFW
MAB_0987c|M.abscessus_ATCC_199 VFNEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHVQHVADYW
MAV_4696|M.avium_104 TFKEFNSDNSAMILLEGDKPLGAEAHRYYDEIVRRVEQDKKHVQHVQDFW
* * .::. *:::**:.*** *: :*: :: .: * :*: : * *
Rv0450c|M.tuberculosis_H37Rv GDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---
MLBr_02378|M.leprae_Br4923 GDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---
MMAR_0775|M.marinum_M GDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---
Mflv_4418|M.gilvum_PYR-GCK GDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---
Mvan_1936|M.vanbaalenii_PYR-1 GDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---
MSMEG_3496|M.smegmatis_MC2_155 GDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---
TH_3260|M.thermoresistible__bu SDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEM
MUL_0757|M.ulcerans_Agy99 GDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---
Mb1583|M.bovis_AF2122/97 GDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP---
MAB_0987c|M.abscessus_ATCC_199 GDPITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRIIAETP---
MAV_4696|M.avium_104 SDPLTAAGSQSHDQKAAYVQVYLAGNMGGGLANESALAVRKIVDSVP---
.**:** * ** * ::*** ** * : *: :*: ::
Rv0450c|M.tuberculosis_H37Rv APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSII
MLBr_02378|M.leprae_Br4923 APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFI
MMAR_0775|M.marinum_M APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLI
Mflv_4418|M.gilvum_PYR-GCK APPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVA
Mvan_1936|M.vanbaalenii_PYR-1 APPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVA
MSMEG_3496|M.smegmatis_MC2_155 APPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIV
TH_3260|M.thermoresistible__bu APEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVI
MUL_0757|M.ulcerans_Agy99 APPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSII
Mb1583|M.bovis_AF2122/97 PPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVV
MAB_0987c|M.abscessus_ATCC_199 APDGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVYRSLI
MAV_4696|M.avium_104 APPGIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSII
.* *: .:*:* .. :* .. . : :. ** ** *:**.
Rv0450c|M.tuberculosis_H37Rv TVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDY
MLBr_02378|M.leprae_Br4923 TVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDY
MMAR_0775|M.marinum_M TVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDY
Mflv_4418|M.gilvum_PYR-GCK TMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDY
Mvan_1936|M.vanbaalenii_PYR-1 TMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDY
MSMEG_3496|M.smegmatis_MC2_155 TVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDY
TH_3260|M.thermoresistible__bu TVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDY
MUL_0757|M.ulcerans_Agy99 TAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDY
Mb1583|M.bovis_AF2122/97 TMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDY
MAB_0987c|M.abscessus_ATCC_199 TTALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAAGTDY
MAV_4696|M.avium_104 TVAVMLGMVFIELAAARGVVATLGNYGVMGLSTFANNMLVLMAIAAGTDY
* * * .:** :* *. :**:.:: .:*. :.** ..**
Rv0450c|M.tuberculosis_H37Rv GIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFA
MLBr_02378|M.leprae_Br4923 GIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFA
MMAR_0775|M.marinum_M AIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFT
Mflv_4418|M.gilvum_PYR-GCK AIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFT
Mvan_1936|M.vanbaalenii_PYR-1 AIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFT
MSMEG_3496|M.smegmatis_MC2_155 AIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFT
TH_3260|M.thermoresistible__bu AIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFT
MUL_0757|M.ulcerans_Agy99 AIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFT
Mb1583|M.bovis_AF2122/97 AIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFT
MAB_0987c|M.abscessus_ATCC_199 AIFFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALFCLSFT
MAV_4696|M.avium_104 AIFVVGRYHEARGLGETREQAFYTMFHSTAHVVLGSGLTIAGAMYCLSFC
.** ***:*** : :: **: .* **::.**:*::** ** *
Rv0450c|M.tuberculosis_H37Rv RMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVR
MLBr_02378|M.leprae_Br4923 RMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVR
MMAR_0775|M.marinum_M RLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTR
Mflv_4418|M.gilvum_PYR-GCK RLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSR
Mvan_1936|M.vanbaalenii_PYR-1 RLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSR
MSMEG_3496|M.smegmatis_MC2_155 RMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTR
TH_3260|M.thermoresistible__bu RLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVR
MUL_0757|M.ulcerans_Agy99 RLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVR
Mb1583|M.bovis_AF2122/97 RLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRTR
MAB_0987c|M.abscessus_ATCC_199 RLPYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKRAMRTR
MAV_4696|M.avium_104 RLPYFQSLGVPCAVGMLVAVLAALTLAPAMLTVASFFK-LMDPKRTLQTR
*:****::* * ::* : : .:*::..::: : * ::*** *
Rv0450c|M.tuberculosis_H37Rv GWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPA
MLBr_02378|M.leprae_Br4923 GWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPA
MMAR_0775|M.marinum_M GWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPT
Mflv_4418|M.gilvum_PYR-GCK GWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPA
Mvan_1936|M.vanbaalenii_PYR-1 GWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPA
MSMEG_3496|M.smegmatis_MC2_155 GWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPA
TH_3260|M.thermoresistible__bu FWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPS
MUL_0757|M.ulcerans_Agy99 GWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPA
Mb1583|M.bovis_AF2122/97 GWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPA
MAB_0987c|M.abscessus_ATCC_199 GWRRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPSSVPS
MAV_4696|M.avium_104 GWRRMGTAVVRWPAPVLAVTIAVALVGLLALPGYKTDYDNRHFLPADTPA
**::*. :**** *:: : :::**::****:* *. : ::* *:
Rv0450c|M.tuberculosis_H37Rv NQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPG
MLBr_02378|M.leprae_Br4923 NQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPG
MMAR_0775|M.marinum_M NVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPG
Mflv_4418|M.gilvum_PYR-GCK NVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPG
Mvan_1936|M.vanbaalenii_PYR-1 NVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPG
MSMEG_3496|M.smegmatis_MC2_155 NTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPG
TH_3260|M.thermoresistible__bu NAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEG
MUL_0757|M.ulcerans_Agy99 NEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEG
Mb1583|M.bovis_AF2122/97 NIGYMAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPG
MAB_0987c|M.abscessus_ATCC_199 NVGYAAAERHFSVARLNPELLMIETDFDMRNPAGMVLLERVAKSVLHARG
MAV_4696|M.avium_104 NVGYAAADRHFDQARLNPELLMIETDHDLRNPADFIVLDKVAKAVFHIPG
* *: .*::** **::**:*::*:*.*:**.:.:::::::*: :: *
Rv0450c|M.tuberculosis_H37Rv ISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQAD
MLBr_02378|M.leprae_Br4923 ISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAE
MMAR_0775|M.marinum_M VARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAA
Mflv_4418|M.gilvum_PYR-GCK VARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQAD
Mvan_1936|M.vanbaalenii_PYR-1 VARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQAD
MSMEG_3496|M.smegmatis_MC2_155 ISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMAD
TH_3260|M.thermoresistible__bu ISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQAD
MUL_0757|M.ulcerans_Agy99 ISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVN
Mb1583|M.bovis_AF2122/97 IGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAE
MAB_0987c|M.abscessus_ATCC_199 VALVQSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYLSQQAD
MAV_4696|M.avium_104 IGRVQTITRPLGTPLDHSTLGFQMGAQAAGRLQTQHYQEEQANNLLKQAD
:. ** :*** *..: *::: * :. . . .: : .
Rv0450c|M.tuberculosis_H37Rv EMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDF
MLBr_02378|M.leprae_Br4923 NMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDF
MMAR_0775|M.marinum_M AMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDF
Mflv_4418|M.gilvum_PYR-GCK AMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDF
Mvan_1936|M.vanbaalenii_PYR-1 AMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDF
MSMEG_3496|M.smegmatis_MC2_155 EMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDF
TH_3260|M.thermoresistible__bu EMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDF
MUL_0757|M.ulcerans_Agy99 DIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDF
Mb1583|M.bovis_AF2122/97 ELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDF
MAB_0987c|M.abscessus_ATCC_199 QMTNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIANFDDQ
MAV_4696|M.avium_104 ELRKTMATLHEQMQVTQDLSNTTHETTRLTKETVQITERLRDDIANFDDF
: : : . : *. :*: ::::**
Rv0450c|M.tuberculosis_H37Rv WRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREM
MLBr_02378|M.leprae_Br4923 WRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNM
MMAR_0775|M.marinum_M WRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRL
Mflv_4418|M.gilvum_PYR-GCK FRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERL
Mvan_1936|M.vanbaalenii_PYR-1 VRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERL
MSMEG_3496|M.smegmatis_MC2_155 LRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRL
TH_3260|M.thermoresistible__bu FRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRL
MUL_0757|M.ulcerans_Agy99 FRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERL
Mb1583|M.bovis_AF2122/97 FRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKL
MAB_0987c|M.abscessus_ATCC_199 FRPIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTGSLTKL
MAV_4696|M.avium_104 LRPIRSYFYWEKHCYDIPVCWALRSVFNALDGIDQVAENIVNLSANLDKL
**:*.***** ** .:* * ::**:*:::**:: : : : : : .:
Rv0450c|M.tuberculosis_H37Rv DRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMG
MLBr_02378|M.leprae_Br4923 DLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMG
MMAR_0775|M.marinum_M DILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMG
Mflv_4418|M.gilvum_PYR-GCK DELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMG
Mvan_1936|M.vanbaalenii_PYR-1 DALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMG
MSMEG_3496|M.smegmatis_MC2_155 DELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMG
TH_3260|M.thermoresistible__bu NDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMG
MUL_0757|M.ulcerans_Agy99 DTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMG
Mb1583|M.bovis_AF2122/97 AAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMG
MAB_0987c|M.abscessus_ATCC_199 DALQPKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRTATELG
MAV_4696|M.avium_104 DRIQPKLVALIPPQIESQQRNLDTIMSNYAITQGLNDQAKAQADNATAQG
: *:: :* : . : . * *
Rv0450c|M.tuberculosis_H37Rv KAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQ
MLBr_02378|M.leprae_Br4923 KAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPA
MMAR_0775|M.marinum_M KAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPA
Mflv_4418|M.gilvum_PYR-GCK EAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPA
Mvan_1936|M.vanbaalenii_PYR-1 EAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPA
MSMEG_3496|M.smegmatis_MC2_155 QAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPM
TH_3260|M.thermoresistible__bu EAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPM
MUL_0757|M.ulcerans_Agy99 EAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPM
Mb1583|M.bovis_AF2122/97 QAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPA
MAB_0987c|M.abscessus_ATCC_199 KAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITHQGDPQ
MAV_4696|M.avium_104 DAFDKAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVRLIISHEGDPA
.*** : ***:**:***.*.. * *.:: *:*.**::.*:** *.***
Rv0450c|M.tuberculosis_H37Rv SPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLL
MLBr_02378|M.leprae_Br4923 SVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLV
MMAR_0775|M.marinum_M STEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLL
Mflv_4418|M.gilvum_PYR-GCK TVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLL
Mvan_1936|M.vanbaalenii_PYR-1 TVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLL
MSMEG_3496|M.smegmatis_MC2_155 SPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLI
TH_3260|M.thermoresistible__bu TPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLI
MUL_0757|M.ulcerans_Agy99 SQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLM
Mb1583|M.bovis_AF2122/97 TPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL
MAB_0987c|M.abscessus_ATCC_199 TSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQKYDLL
MAV_4696|M.avium_104 SPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLL
: *: : * . :::*.** .: :*:.**.: ::*: :* **:
Rv0450c|M.tuberculosis_H37Rv IAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHIL
MLBr_02378|M.leprae_Br4923 IAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHIL
MMAR_0775|M.marinum_M IAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIF
Mflv_4418|M.gilvum_PYR-GCK IAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHII
Mvan_1936|M.vanbaalenii_PYR-1 IAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHII
MSMEG_3496|M.smegmatis_MC2_155 IAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHII
TH_3260|M.thermoresistible__bu IAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIV
MUL_0757|M.ulcerans_Agy99 IAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVL
Mb1583|M.bovis_AF2122/97 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLL
MAB_0987c|M.abscessus_ATCC_199 MAALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVVWQYIF
MAV_4696|M.avium_104 IAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYLL
:*.::: **::**:.:**:.:*: ****** :**.****:**::** :.
Rv0450c|M.tuberculosis_H37Rv AIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGT
MLBr_02378|M.leprae_Br4923 GIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGT
MMAR_0775|M.marinum_M GVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGT
Mflv_4418|M.gilvum_PYR-GCK GLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGT
Mvan_1936|M.vanbaalenii_PYR-1 GLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGT
MSMEG_3496|M.smegmatis_MC2_155 GLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGT
TH_3260|M.thermoresistible__bu GLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGS
MUL_0757|M.ulcerans_Agy99 GIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGS
Mb1583|M.bovis_AF2122/97 GIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGT
MAB_0987c|M.abscessus_ATCC_199 GIPLYWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIRAIAGT
MAV_4696|M.avium_104 GLKLHWMVLAMAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGS
.: ::::::.:::*:*****:*****:::*:::* .*::** **::.*:
Rv0450c|M.tuberculosis_H37Rv GKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
MLBr_02378|M.leprae_Br4923 GKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMP
MMAR_0775|M.marinum_M GGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
Mflv_4418|M.gilvum_PYR-GCK GSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP
Mvan_1936|M.vanbaalenii_PYR-1 GSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP
MSMEG_3496|M.smegmatis_MC2_155 GSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTP
TH_3260|M.thermoresistible__bu GSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMP
MUL_0757|M.ulcerans_Agy99 GSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTP
Mb1583|M.bovis_AF2122/97 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTP
MAB_0987c|M.abscessus_ATCC_199 GGVVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRSFLTP
MAV_4696|M.avium_104 GSVVTSAGLVFAATMATFMFSPLLVMAQVGTTIALGLLFDTLIVRSFMTP
* *** *****. ** : .* * *:.*:****.:******:::*:*: *
Rv0450c|M.tuberculosis_H37Rv SIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----
MLBr_02378|M.leprae_Br4923 SIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD---------
MMAR_0775|M.marinum_M SIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPE
Mflv_4418|M.gilvum_PYR-GCK AVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR-------------
Mvan_1936|M.vanbaalenii_PYR-1 AVAALLGRWFWWPQKVRSHASQRRLAALNH--------------------
MSMEG_3496|M.smegmatis_MC2_155 SIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV----------
TH_3260|M.thermoresistible__bu SIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV--------
MUL_0757|M.ulcerans_Agy99 SIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-----------
Mb1583|M.bovis_AF2122/97 SIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQV
MAB_0987c|M.abscessus_ATCC_199 AIATMLGRWFWWPINIRTRPAP---KPFGPKP--------TGADDTTGPI
MAV_4696|M.avium_104 SLATLLGRWFWWPQHVRPRPASTMLRPYGPRRAVRELILADVDEHPPGGV
::*.::*:***** * .
Rv0450c|M.tuberculosis_H37Rv --------------
MLBr_02378|M.leprae_Br4923 --------------
MMAR_0775|M.marinum_M DTNTERLAVSSPHY
Mflv_4418|M.gilvum_PYR-GCK --------------
Mvan_1936|M.vanbaalenii_PYR-1 --------------
MSMEG_3496|M.smegmatis_MC2_155 --------------
TH_3260|M.thermoresistible__bu --------------
MUL_0757|M.ulcerans_Agy99 --------------
Mb1583|M.bovis_AF2122/97 ATHR----------
MAB_0987c|M.abscessus_ATCC_199 PVSG----------
MAV_4696|M.avium_104 VQPR----------