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M. thermoresistible (build 8) TH_3260 (-)

annotation: MmpL4 protein
coordinates: 412570 - 415500
length: 977

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3260--100% (977)MmpL4 protein
M. thermoresistible (build 8)TH_3056-0.054.69% (938) PUTATIVE Mmp14a protein
M. thermoresistible (build 8)TH_2972-0.060.32% (557) PUTATIVE putative transport protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0695cmmpL50.070.19% (936) transmembrane transport protein MmpL5
M. gilvum PYR-GCKMflv_3435-0.071.06% (964) transport protein
M. tuberculosis H37RvRv0676cmmpL50.070.09% (936) transmembrane transport protein MmpL5
M. leprae Br4923MLBr_02378-0.057.63% (930) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_2301-0.061.08% (943) putative membrane protein, mmpL
M. marinum MMMAR_1005mmpL50.067.95% (964) transmembrane transport protein, MmpL5
M. avium 104MAV_2510-0.065.42% (966) MmpL4 protein
M. smegmatis MC2 155MSMEG_0225-0.069.81% (964) MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.067.43% (967) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_3189-0.070.48% (962) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3260|M.thermoresistible__bu      MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
MSMEG_0225|M.smegmatis_MC2_155      -MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALIA
Mb0695c|M.bovis_AF2122/97           MIVQRTAAPTGSVPPDRHA------ARPFIPRMIRTFAVPIILGWLVTIA
Rv0676c|M.tuberculosis_H37Rv        MIVQRTAAPTGSVPPDRHA------ARPFIPRMIRTFAVPIILGWLVTIA
MMAR_1005|M.marinum_M               MTATTTDTPTDVVPPAEHP------PRPFIPRMIRTFAVPLILGWVLLIA
MUL_0757|M.ulcerans_Agy99           MTATTTDTPTDVVPPAEHP------PRPFIPRMIRTFAVPLILGWVLLIA
Mflv_3435|M.gilvum_PYR-GCK          MSAPVSDARTDEFPAAHGP------HRSFIPRMIRLFAVPIILGWIALIV
Mvan_3189|M.vanbaalenii_PYR-1       MSAPVSDARTDEFPAARQP------HRPFIPRMIRLFAVPIILGWIALIV
MAV_2510|M.avium_104                MSTTFDDTRTDAIPVVKEP------VREKIPRFIRAFAVPIIIGWIALIA
MLBr_02378|M.leprae_Br4923          ----MTVKCANDLDTHTKP--------PFVARMIHRFAVPIILVWLAIAV
MAB_2301|M.abscessus_ATCC_1997      ----MSGSHAG--RSAAEP--------TFLAKWIRRLSIPIVIGWLAIVF
                                             :                   :.  *: :::*::: *:    

TH_3260|M.thermoresistible__bu      LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV
MSMEG_0225|M.smegmatis_MC2_155      VLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMIV
Mb0695c|M.bovis_AF2122/97           VLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMIV
Rv0676c|M.tuberculosis_H37Rv        VLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMIV
MMAR_1005|M.marinum_M               VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
MUL_0757|M.ulcerans_Agy99           VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
Mflv_3435|M.gilvum_PYR-GCK          VVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIV
Mvan_3189|M.vanbaalenii_PYR-1       ILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIV
MAV_2510|M.avium_104                VLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIV
MLBr_02378|M.leprae_Br4923          TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV
MAB_2301|M.abscessus_ATCC_1997      ALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIV
                                     :.  :*.*: **: ::*.::*. * *  : :::* :* * .*:*  ***

TH_3260|M.thermoresistible__bu      LEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPDG
MSMEG_0225|M.smegmatis_MC2_155      LEGEQPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQSSDG
Mb0695c|M.bovis_AF2122/97           LEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDG
Rv0676c|M.tuberculosis_H37Rv        LEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDG
MMAR_1005|M.marinum_M               LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG
MUL_0757|M.ulcerans_Agy99           LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG
Mflv_3435|M.gilvum_PYR-GCK          FEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDG
Mvan_3189|M.vanbaalenii_PYR-1       FEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDG
MAV_2510|M.avium_104                LEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSNDG
MLBr_02378|M.leprae_Br4923          LEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDG
MAB_2301|M.abscessus_ATCC_1997      LEGQERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQSTDG
                                    :**:. **  :: :** :: :*.**  *:: :**:*.**** .* ** **

TH_3260|M.thermoresistible__bu      KSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGVQAF
MSMEG_0225|M.smegmatis_MC2_155      LASYVQVYTAGNQGEALANESVKAVQDIVDSV---------QAPPGVTAY
Mb0695c|M.bovis_AF2122/97           KAAYVQVKLAGNQGESLANESVEAVKTIVERLA---------PPPGVKVY
Rv0676c|M.tuberculosis_H37Rv        KAAYVQVKLAGNQGESLANESVEAVKTIVERLA---------PPPGVKVY
MMAR_1005|M.marinum_M               KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---------APPGVKVY
MUL_0757|M.ulcerans_Agy99           KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---------APPGVKVY
Mflv_3435|M.gilvum_PYR-GCK          KAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---------PPPGVRAF
Mvan_3189|M.vanbaalenii_PYR-1       KAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---------PPPGVRAF
MAV_2510|M.avium_104                KASYVQVYLAGNQGEALANESVESVQNIVKSVQ---------APNGVKAY
MLBr_02378|M.leprae_Br4923          KAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGITAW
MAB_2301|M.abscessus_ATCC_1997      KATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLTVY
                                     ::***:  :** ** *::** .:.:  :              * *: .:

TH_3260|M.thermoresistible__bu      VTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFM
MSMEG_0225|M.smegmatis_MC2_155      VTGPAAMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSLVM
Mb0695c|M.bovis_AF2122/97           VTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTM
Rv0676c|M.tuberculosis_H37Rv        VTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTM
MMAR_1005|M.marinum_M               VTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTM
MUL_0757|M.ulcerans_Agy99           VTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTM
Mflv_3435|M.gilvum_PYR-GCK          VTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVM
Mvan_3189|M.vanbaalenii_PYR-1       VTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVM
MAV_2510|M.avium_104                VTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVM
MLBr_02378|M.leprae_Br4923          VTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFT
MAB_2301|M.abscessus_ATCC_1997      VTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVFML
                                    *** .*: :* : :.* *:  *   :. **   **:.***..*  : :  

TH_3260|M.thermoresistible__bu      VLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRY
MSMEG_0225|M.smegmatis_MC2_155      VVFSLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIGRY
Mb0695c|M.bovis_AF2122/97           VVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY
Rv0676c|M.tuberculosis_H37Rv        VVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY
MMAR_1005|M.marinum_M               VVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY
MUL_0757|M.ulcerans_Agy99           VVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY
Mflv_3435|M.gilvum_PYR-GCK          VVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRY
Mvan_3189|M.vanbaalenii_PYR-1       VVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRY
MAV_2510|M.avium_104                VVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRY
MLBr_02378|M.leprae_Br4923          VGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRY
MAB_2301|M.abscessus_ATCC_1997      VGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIGRY
                                    * :   .:** :*:**   :**** **..**. *:** ..**.**: ***

TH_3260|M.thermoresistible__bu      QEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSL
MSMEG_0225|M.smegmatis_MC2_155      QEARSVGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSL
Mb0695c|M.bovis_AF2122/97           QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL
Rv0676c|M.tuberculosis_H37Rv        QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL
MMAR_1005|M.marinum_M               QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL
MUL_0757|M.ulcerans_Agy99           QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL
Mflv_3435|M.gilvum_PYR-GCK          QEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTM
Mvan_3189|M.vanbaalenii_PYR-1       QEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTL
MAV_2510|M.avium_104                QEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTL
MLBr_02378|M.leprae_Br4923          QEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTL
MAB_2301|M.abscessus_ATCC_1997      QEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQTL
                                    ****  . .:  *:: *: .* **: .**:**:**  ** *:.:****::

TH_3260|M.thermoresistible__bu      GPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGAS
MSMEG_0225|M.smegmatis_MC2_155      GIPLAIGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRGWRKVGAA
Mb0695c|M.bovis_AF2122/97           GVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAA
Rv0676c|M.tuberculosis_H37Rv        GVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAA
MMAR_1005|M.marinum_M               GVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAA
MUL_0757|M.ulcerans_Agy99           GVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAA
Mflv_3435|M.gilvum_PYR-GCK          GVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAA
Mvan_3189|M.vanbaalenii_PYR-1       GVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAA
MAV_2510|M.avium_104                GIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTV
MLBr_02378|M.leprae_Br4923          GVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTV
MAB_2301|M.abscessus_ATCC_1997      GVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIGTT
                                    * * ::*: : : ..: :  * ::: :**   :**:*  : * **::*: 

TH_3260|M.thermoresistible__bu      VVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAE
MSMEG_0225|M.smegmatis_MC2_155      VVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAAAD
Mb0695c|M.bovis_AF2122/97           IVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAE
Rv0676c|M.tuberculosis_H37Rv        IVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAE
MMAR_1005|M.marinum_M               IVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAE
MUL_0757|M.ulcerans_Agy99           IVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAE
Mflv_3435|M.gilvum_PYR-GCK          IVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVAD
Mvan_3189|M.vanbaalenii_PYR-1       VVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVAD
MAV_2510|M.avium_104                VVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAAD
MLBr_02378|M.leprae_Br4923          VVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAAD
MAB_2301|M.abscessus_ATCC_1997      IVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQAAD
                                    :**** *::  : .::::** :****:*.*.*: * * .:*:* *: .*:

TH_3260|M.thermoresistible__bu      RHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGIT
MSMEG_0225|M.smegmatis_MC2_155      RHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQAIT
Mb0695c|M.bovis_AF2122/97           RHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAIT
Rv0676c|M.tuberculosis_H37Rv        RHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAIT
MMAR_1005|M.marinum_M               RHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAIT
MUL_0757|M.ulcerans_Agy99           RHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAIT
Mflv_3435|M.gilvum_PYR-GCK          EHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAIT
Mvan_3189|M.vanbaalenii_PYR-1       RHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAIT
MAV_2510|M.avium_104                RHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAIT
MLBr_02378|M.leprae_Br4923          RHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAIT
MAB_2301|M.abscessus_ATCC_1997      RHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQAIT
                                    .**  **::**:*::*****:**.:***:::::*: :. * *:.***.**

TH_3260|M.thermoresistible__bu      RPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDT
MSMEG_0225|M.smegmatis_MC2_155      RPQGTPIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTVDT
Mb0695c|M.bovis_AF2122/97           RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQ
Rv0676c|M.tuberculosis_H37Rv        RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQ
MMAR_1005|M.marinum_M               RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQ
MUL_0757|M.ulcerans_Agy99           RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQ
Mflv_3435|M.gilvum_PYR-GCK          RPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKT
Mvan_3189|M.vanbaalenii_PYR-1       RPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIAT
MAV_2510|M.avium_104                RPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDS
MLBr_02378|M.leprae_Br4923          RPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIAS
MAB_2301|M.abscessus_ATCC_1997      RPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENVVI
                                    **:*..:.*:**** :* *.. *  . :  :*    :  *.: :   :  

TH_3260|M.thermoresistible__bu      MDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYF
MSMEG_0225|M.smegmatis_MC2_155      MTKMIALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRNYL
Mb0695c|M.bovis_AF2122/97           MERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYF
Rv0676c|M.tuberculosis_H37Rv        MERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYF
MMAR_1005|M.marinum_M               MERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYF
MUL_0757|M.ulcerans_Agy99           MERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYF
Mflv_3435|M.gilvum_PYR-GCK          MEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYF
Mvan_3189|M.vanbaalenii_PYR-1       MEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYF
MAV_2510|M.avium_104                MEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYF
MLBr_02378|M.leprae_Br4923          MRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYF
MAB_2301|M.abscessus_ATCC_1997      MKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRNYL
                                    * :       :    . :: .   :     .:*: :::*:*::**:*.*:

TH_3260|M.thermoresistible__bu      YWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQML
MSMEG_0225|M.smegmatis_MC2_155      YWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPVMI
Mb0695c|M.bovis_AF2122/97           YWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLT
Rv0676c|M.tuberculosis_H37Rv        YWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLT
MMAR_1005|M.marinum_M               YWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMT
MUL_0757|M.ulcerans_Agy99           YWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMT
Mflv_3435|M.gilvum_PYR-GCK          YWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMV
Mvan_3189|M.vanbaalenii_PYR-1       YWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMV
MAV_2510|M.avium_104                YWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMV
MLBr_02378|M.leprae_Br4923          YWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQML
MAB_2301|M.abscessus_ATCC_1997      YWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPKMV
                                    *** **::**:*:::**:**::* :: :   :  ::  :..:: *:* : 

TH_3260|M.thermoresistible__bu      TLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARN
MSMEG_0225|M.smegmatis_MC2_155      ANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKAKN
Mb0695c|M.bovis_AF2122/97           AMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRN
Rv0676c|M.tuberculosis_H37Rv        AMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRN
MMAR_1005|M.marinum_M               AMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRN
MUL_0757|M.ulcerans_Agy99           AMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRN
Mflv_3435|M.gilvum_PYR-GCK          ALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMN
Mvan_3189|M.vanbaalenii_PYR-1       ALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMN
MAV_2510|M.avium_104                ALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKN
MLBr_02378|M.leprae_Br4923          EQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKN
MAB_2301|M.abscessus_ATCC_1997      SDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAAKN
                                      :   :  *: *:  :*:   :  *  :*    ..:: :**:*** : *

TH_3260|M.thermoresistible__bu      DDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKI
MSMEG_0225|M.smegmatis_MC2_155      DDSFYLPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQKI
Mb0695c|M.bovis_AF2122/97           DDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARI
Rv0676c|M.tuberculosis_H37Rv        DDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARI
MMAR_1005|M.marinum_M               DDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHI
MUL_0757|M.ulcerans_Agy99           DDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHI
Mflv_3435|M.gilvum_PYR-GCK          DDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKI
Mvan_3189|M.vanbaalenii_PYR-1       DDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKI
MAV_2510|M.avium_104                DDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHI
MLBr_02378|M.leprae_Br4923          DDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASI
MAB_2301|M.abscessus_ATCC_1997      DDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLSHV
                                    ********* *.* :*::.:: *:*.**:*.*:** * *** :  *:  :

TH_3260|M.thermoresistible__bu      EPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVC
MSMEG_0225|M.smegmatis_MC2_155      DDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLIIAGIAALC
Mb0695c|M.bovis_AF2122/97           AKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALC
Rv0676c|M.tuberculosis_H37Rv        AKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALC
MMAR_1005|M.marinum_M               DKIKTAAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMIAGISALC
MUL_0757|M.ulcerans_Agy99           DKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALC
Mflv_3435|M.gilvum_PYR-GCK          DKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALG
Mvan_3189|M.vanbaalenii_PYR-1       DKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALG
MAV_2510|M.avium_104                GAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLC
MLBr_02378|M.leprae_Br4923          NAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLC
MAB_2301|M.abscessus_ATCC_1997      EPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISALC
                                      *: ** **:******.: : *.**.: :**:.:* .:**:**.*::: 

TH_3260|M.thermoresistible__bu      LIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMV
MSMEG_0225|M.smegmatis_MC2_155      LIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHWMV
Mb0695c|M.bovis_AF2122/97           LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV
Rv0676c|M.tuberculosis_H37Rv        LIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV
MMAR_1005|M.marinum_M               LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV
MUL_0757|M.ulcerans_Agy99           LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLV
Mflv_3435|M.gilvum_PYR-GCK          LIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMV
Mvan_3189|M.vanbaalenii_PYR-1       LIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMV
MAV_2510|M.avium_104                LIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMV
MLBr_02378|M.leprae_Br4923          LIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLV
MAB_2301|M.abscessus_ATCC_1997      LIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHWLV
                                    ***:***: **..**: ****** :**.::**:**::**:::*  :*::*

TH_3260|M.thermoresistible__bu      FPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAG
MSMEG_0225|M.smegmatis_MC2_155      LAMAVIVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTAAG
Mb0695c|M.bovis_AF2122/97           LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG
Rv0676c|M.tuberculosis_H37Rv        LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG
MMAR_1005|M.marinum_M               LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG
MUL_0757|M.ulcerans_Agy99           LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG
Mflv_3435|M.gilvum_PYR-GCK          LAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAG
Mvan_3189|M.vanbaalenii_PYR-1       LAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAG
MAV_2510|M.avium_104                LAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAG
MLBr_02378|M.leprae_Br4923          LAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAG
MAB_2301|M.abscessus_ATCC_1997      MQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTSAG
                                    : *::*:*****:*****:*:*:::*: .*: **:**:***:*.*** **

TH_3260|M.thermoresistible__bu      LVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGR
MSMEG_0225|M.smegmatis_MC2_155      LVFAFTMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPSIAALLGK
Mb0695c|M.bovis_AF2122/97           LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK
Rv0676c|M.tuberculosis_H37Rv        LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK
MMAR_1005|M.marinum_M               LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK
MUL_0757|M.ulcerans_Agy99           LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK
Mflv_3435|M.gilvum_PYR-GCK          LVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGP
Mvan_3189|M.vanbaalenii_PYR-1       LVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGP
MAV_2510|M.avium_104                LVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGK
MLBr_02378|M.leprae_Br4923          LVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGR
MAB_2301|M.abscessus_ATCC_1997      LVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLLGR
                                    ***.:**  : **:* ::.******.:******:::*::* *::*:*** 

TH_3260|M.thermoresistible__bu      WFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV----------------
MSMEG_0225|M.smegmatis_MC2_155      WFWWPQMVRRRPKPSPWPKPIQREPADAVN-------------------
Mb0695c|M.bovis_AF2122/97           WFWWPQVVRQRPVPQPWPSPASARTFALV--------------------
Rv0676c|M.tuberculosis_H37Rv        WFWWPQVVRQRPIPQPWPSPASARTFALV--------------------
MMAR_1005|M.marinum_M               WFWWPQVVRQRPAPQPWPTPAPTP--ATTSV------------------
MUL_0757|M.ulcerans_Agy99           WFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------------------
Mflv_3435|M.gilvum_PYR-GCK          WFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA----------------
Mvan_3189|M.vanbaalenii_PYR-1       WFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV----------------
MAV_2510|M.avium_104                WFWWPQRVRQRPVPSPWPKPAAQEREVLADA------------------
MLBr_02378|M.leprae_Br4923          WFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD-----------------
MAB_2301|M.abscessus_ATCC_1997      WFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPSV
                                    *****   * **     .