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SKRLSRTESQELTRAKLIESATRLYLENGYVATSTDQVAEAAGFSRGALYSNFRSKEDLALAVLDAHTEE QFQEIAAVAADLPPERFTRFETWLTKSMGDRRWALFKSEVALSARANPELRQQLAARDQLARQALSVLLG HVEAESGNPLPAAPETLARAILALAKGIAIEGLVDDEVSPDWIIDLVKKGLPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3437c | - | - | 100% (194) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2913 | - | 9e-18 | 29.55% (176) | TetR family regulatory protein |
| M. abscessus ATCC 19977 | MAB_0145c | - | 1e-16 | 32.23% (211) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3185c | - | 1e-10 | 26.92% (182) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 6e-18 | 31.38% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3160c | - | 1e-10 | 26.92% (182) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 4e-08 | 40.30% (67) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 9e-16 | 29.26% (188) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 8e-15 | 29.28% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 1e-17 | 30.39% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3775 | - | 8e-08 | 27.71% (166) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_0245 | - | 1e-11 | 27.49% (171) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 2e-18 | 32.61% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2327|M.gilvum_PYR-GCK --------------------------MAERWTKERRTEHTRQILLDAAEE
Mvan_4321|M.vanbaalenii_PYR-1 --------------------------MAERWTKERRTEHTRQILLDAAEE
MSMEG_6807|M.smegmatis_MC2_155 --------------------------MVERWTRERRLEHTRSLLLDAAEN
Mb3185c|M.bovis_AF2122/97 --------------------------MPR---QAGRWSPTALRILGAAAE
Rv3160c|M.tuberculosis_H37Rv --------------------------MPR---QAGRWSPTALRILGAAAE
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
MAB_3437c|M.abscessus_ATCC_199 --------------------------MSKRLSRTESQELTRAKLIESATR
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
TH_3775|M.thermoresistible__bu ----------------------------------MAETDDKNRVLATATT
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mflv_2327|M.gilvum_PYR-GCK VFARKGLTGAALEEIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLD
Mvan_4321|M.vanbaalenii_PYR-1 VFARKGLTGAALEEIAEAAGFTRGAIYSQFGAKEKLFLAVVDRQRQRFLD
MSMEG_6807|M.smegmatis_MC2_155 VFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
Mb3185c|M.bovis_AF2122/97 LIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLE
Rv3160c|M.tuberculosis_H37Rv LIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLE
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MAB_3437c|M.abscessus_ATCC_199 LYLENGYVATSTDQVAEAAGFSRGALYSNFRSKEDLALAVLDAHTEEQFQ
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
TH_3775|M.thermoresistible__bu LFNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRR
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: .* . : .* .*. * : .: ::
Mflv_2327|M.gilvum_PYR-GCK GFADVMDS-------FHRLSDVDIDELAQR-----WRQLSS--GADRAAL
Mvan_4321|M.vanbaalenii_PYR-1 GFADVMMS-------FHRLSDVDIDELAER-----WRQLSS--GPDRAAL
MSMEG_6807|M.smegmatis_MC2_155 NFAEVMAS-------AASVGARELDEIAKR-----WRQLSVDRGAEQAAL
Mb3185c|M.bovis_AF2122/97 LFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVA
Rv3160c|M.tuberculosis_H37Rv LFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVA
MMAR_4631|M.marinum_M QVGTAMAS---------VDDPTDVPGTVDR------IASTLLLDRDWLLI
MUL_0245|M.ulcerans_Agy99 QVGTAMAS---------VGDPTDVPGTVDR------IASTLLLDRDWLLI
MAB_3437c|M.abscessus_ATCC_199 EIAAVAAD----------LPPERFTRFETW-------LTKSMGDRRWALF
MAV_1611|M.avium_104 QIAIALDR--------SAGDTTAAAREVSR-----SVLDSVRDHSDYYVL
TH_3775|M.thermoresistible__bu AMTEYVQS--------------RAADPRDR-------ILAVFDFLAHWFA
MLBr_00815|M.leprae_Br4923 SVQQALRT--------TTNNRQRLHAAVQA----FFDFIEHDGQGYRLIF
.
Mflv_2327|M.gilvum_PYR-GCK GYELTLYLLRNPDARASVA---AQRRETIRALGEFISKNVARIGGTLTIE
Mvan_4321|M.vanbaalenii_PYR-1 GHELTLYLLRNPEARESVA---GQRRETVRALGEFISKNVARIGGTLTIE
MSMEG_6807|M.smegmatis_MC2_155 GLEFTLYLKRNPEARDRVA---AKRSEVVAQLTAFIVASIEKLGATLLIS
Mb3185c|M.bovis_AF2122/97 ERELVAEMERALVGLIETG---QGEGDVRAMHPLSAARLVQALFDALALP
Rv3160c|M.tuberculosis_H37Rv ERELVAEMERALVGLIETG---QGEGDVRAMHPLSAARLVQALFDALALP
MMAR_4631|M.marinum_M KTDFLMHAARHPDLAQRLA---AHRAQLRAAVEDRLAGSDVELPAAIGSV
MUL_0245|M.ulcerans_Agy99 KTDFLMHAARHPDLAQRLA---AHRAQLRAAVEDRLAGSDVELPAAIGSV
MAB_3437c|M.abscessus_ATCC_199 KSEVALSARANPELRQQLA---ARDQLARQALSVLLGHVEAESGNPLPAA
MAV_1611|M.avium_104 LVEYWLRAQRDPQLRERLI---ERRRAAADQALHIVESTDTVPGD---RR
TH_3775|M.thermoresistible__bu ESDFRGCMFINTIGELGGT---STDVRRIARLHKTAVRDYLADLVAAAEL
MLBr_00815|M.leprae_Br4923 ENDNITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGI
:
Mflv_2327|M.gilvum_PYR-GCK AETLARIVLAANDGVTLDSHIDG-EDLYRPYLQLVMSSVQTPH---
Mvan_4321|M.vanbaalenii_PYR-1 AETLARVVLAANDGITLNSHLDG-EDLYRPYLQLVISSVQTPP---
MSMEG_6807|M.smegmatis_MC2_155 PETFAHALVATSDSVVLSSELDN-VDLYRPMVEMYASMIKLPT---
Mb3185c|M.bovis_AF2122/97 EFAVSPDEIVEFAMTALLSDPDR-LAEIRAAADALEIQTAPPDRGL
Rv3160c|M.tuberculosis_H37Rv EFAVSPDEIVEFAMTALLSDPDR-LAEIRAAADALEIQTAPPDRGL
MMAR_4631|M.marinum_M ADAAR-AVVAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR----
MUL_0245|M.ulcerans_Agy99 ADAAR-AVVAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR----
MAB_3437c|M.abscessus_ATCC_199 PETLARAILALAKGIAIEGLVDD--EVSPDWIIDLVKKGLPQ----
MAV_1611|M.avium_104 LTDIAQLVVTLNLGVAMEEVLRP-GTINPDLLAQLITALLESIPV-
TH_3775|M.thermoresistible__bu PSELAEQLAILADGAIVAATIWGDGTDAAAAARRAAATLISAS---
MLBr_00815|M.leprae_Br4923 SVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL------