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TLTEREHELDELAARYAAACKGRGGAVLVCGESGAGKTSFVEAFVAGLPAGTRVLWGACDPLSTPRPLGP LHDLAANFTAATQSHLSSGQPYDIFAAVLDELRTQPAVLVLDDLHWADQGTIDLLRFLLRRAPQSHLLTI GILRDEEVSVTHPLRALFGDIARSSHGQSLTLPPLSVRAVETLIGDRDVDPERLHRITGGNAFFVCEMLD HDGADLPTSVRDAILARTADLDAAAWDLLNLLTCAPGAIGDHLLTGLGVTLPALRALDQAKLIKRDARGV AFRHDLCRRAITSVIPPGAEPGLHRRFLDAHRDAHDEDPAVLTHHALGGGDRALITTAAAQAGRAAARSG AHTQACEFFQIALERGGLLDDGAEAELLERLAEEYYLTDRLEDAISACRRAMRIRRDTRAPVAVSANHHS LAVYEWYSGNRAVADEHVAEAIAALADVDAEQDPSCLGQLGHGFAMQAFLAVQSSRVDAARKALDRAREI ASRAGDPNLSVRVRLIGYYCDISAGESLVRDRLLSELAAGPRHIDETYSGGYTNLTYYDVEHRRLGEAAA VLGTSIPLMVEHDLPICRVVQLGSRSRLNLLVGDWDDALADADAVLNSRSAPLARTWPLLIRGLVALRRT GDDGGVIDDAWQLARRFGELVRLLPAASAIAERVWLTGTYDKRLDGCHSMLAEAPARGLEWARGELGMWL RRIGAADSPVSDVAEPYALLSDGCHEAAAAAFHRLSTPYDAALALVESGEPAAVRRALDALDRLGADAVA NKVRADLRATGATAVPGPRRASTLSNPAGLTVRQVEVLRLLGDGLTNAELAERLFLSVKTVDHHVSAILT KLDVTKRRDAVRRAREVGILT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1929 | - | - | 100% (862) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 2e-23 | 24.14% (957) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_3871 | - | 1e-21 | 25.50% (949) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1393 | - | 8e-10 | 24.13% (489) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1156 | - | 3e-26 | 24.31% (942) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv1358 | - | 8e-10 | 24.13% (489) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02341 | - | 5e-08 | 23.79% (454) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 1e-19 | 24.79% (851) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 1e-17 | 23.55% (951) | transcriptional regulatory protein |
| M. avium 104 | MAV_5280 | - | 2e-08 | 37.14% (105) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 6e-22 | 24.71% (943) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 3e-16 | 23.60% (962) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 3e-08 | 34.00% (150) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1393|M.bovis_AF2122/97 MFLSAPAFRVEPTRSRHSALRWARHRRFADVPRWQMLRSLQIADQIARTG
Rv1358|M.tuberculosis_H37Rv MFLSAPAFRVEPTRSRHSALRWARHRRFADGPRWQMLRSLQIADQIARTG
MSMEG_0321|M.smegmatis_MC2_155 -------------------------------------METGGRGQPLHGR
TH_3225|M.thermoresistible__bu -------------------------------------MSSRDGDVVLHGR
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M -----------------------------------------MPTVTLVGR
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 --------------------------------------------MTLTER
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGS--TRLSQ
Rv1358|M.tuberculosis_H37Rv HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGS--TRLSQ
MSMEG_0321|M.smegmatis_MC2_155 AAECDALRRSIADVQSAQSRVLVLRGEAGVGKTALLDFAAQHA--KGFRI
TH_3225|M.thermoresistible__bu AAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLGQLLGDA--AGMRC
MAB_3361|M.abscessus_ATCC_1997 ----------------------MLRGQAGVGKTALLRYVLGKA--SGQLI
MMAR_0085|M.marinum_M HREQQQLQQLLDAARRGESGVLVLRGDAGIGKTTLLTDLVDNA--PDLRV
Mflv_1156|M.gilvum_PYR-GCK ---MKAVDDFLAGLQQLQPAGLLIEGEAGIGKTTMLAGVVDAARQAGFRV
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 EHELDELAARYAAACKGRGGAVLVCGESGAGKTSFVEAFVAGLP-AGTRV
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 TRLNELAADYPTLDQNISEAVA-AHGGVTRPVDQEVGSGLVVAFLRAGDA
Rv1358|M.tuberculosis_H37Rv TRLNELAADYPTLDQNISEAVA-AHGGVTRPVDQEVGSGLVVAFLRAGDA
MSMEG_0321|M.smegmatis_MC2_155 TQVAGVESDMELAYAGLQQLCA-PLMNNLDDLPEPQRDALAVAFGLGVGQ
TH_3225|M.thermoresistible__bu VQVAGVESDMELAYAGLHQLCA-PLLDRLDDLPSPQRDVLNVAFGRGAGP
MAB_3361|M.abscessus_ATCC_1997 AQASGIQSEMELAFAGLQQFCA-PLTKYSGAIPDPQREALTIAFGTRSGP
MMAR_0085|M.marinum_M LRVRGAEMEMELTYSGVQQLCG-PLMSLIGQLPEPQLDALEIALGRKRGR
Mflv_1156|M.gilvum_PYR-GCK LSAHGDQSGSGLAHAAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGT
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 LWGACDPLSTPRPLGPLHDLAANFTAATQSHLSSGQ--------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGS
Mb1393|M.bovis_AF2122/97 --IACALELQLSTLAPMRPRVGVHTGDVRLRGDGTITGSAINESACLRDL
Rv1358|M.tuberculosis_H37Rv --IACALELQLSTLAPMRPRVGVHTGDVRLRGDGTITGSAINESACLRDL
MSMEG_0321|M.smegmatis_MC2_155 --TPDRFLVGLAVLSLMAAAADEKP------LLCIVDDAQWLDSVSVQTL
TH_3225|M.thermoresistible__bu --APGRFLVGLAVLNLLAAAGADQP------LLCVIDDAQWLDRVSLQTL
MAB_3361|M.abscessus_ATCC_1997 --PPDRFLIGLAVLSLLAAAAEHQP------VLCVIDDAQWLDRVSLQTL
MMAR_0085|M.marinum_M --APDRLLLGLAVLTLVGEASRASP------ILCVVDDAQWVDSASVQAL
Mflv_1156|M.gilvum_PYR-GCK GGPTDERVIAAALLGAVHGSATRTP------VLVAVDDVQWLDPSSVAVL
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 ---------PYDIFAAVLDELRTQP------AVLVLDDLHWADQGTIDLL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 ----------MDIAAAVGLER----------LREIMTELVSRAAGVIERY
Mb1393|M.bovis_AF2122/97 AHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRD
Rv1358|M.tuberculosis_H37Rv AHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRD
MSMEG_0321|M.smegmatis_MC2_155 AFVARRLLAEPVGLIFAVRDHGAPALAGLPELLVDGLSDTD------ARE
TH_3225|M.thermoresistible__bu GFVARRLMAEPVAMVFALRDDIHEALVGVPALAVPGLADAD------ART
MAB_3361|M.abscessus_ATCC_1997 AFVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHGLRAAD------AGT
MMAR_0085|M.marinum_M AFVARRIHVDPVAMVFATRDRGPDALTGHCELSLQGLEDHD------ARL
Mflv_1156|M.gilvum_PYR-GCK AFVARRVKG-RVGFVVAERPGVGPGLPAATWLQVGTGALTRLPVAPMSLG
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 RFLLRRAPQSHLLTIGILRDEEVSVTHPLRALFGDIARSSHGQSLTLPPL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 GGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKAR---------
Mb1393|M.bovis_AF2122/97 LRNEFPPLRMSVGN-RSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG
Rv1358|M.tuberculosis_H37Rv LRNEFPPLRMSVGN-RSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG
MSMEG_0321|M.smegmatis_MC2_155 LLDSVILGRLDERV-RDRVVAETR---GIPLALLEVPRTIPAAELAGGFS
TH_3225|M.thermoresistible__bu LLEHMFPGAIDANV-RDRLVAESR---GNPLALLEVPRTYAVGELAGGFV
MAB_3361|M.abscessus_ATCC_1997 LLDSVIPGLLDERV-RDRIVAETQ---GNPLALLELPRDMTAEELAGGFG
MMAR_0085|M.marinum_M VLSTAIPGRLNDSV-AETVLAEAN---GNPLALLELHNALIRGELAGGYG
Mflv_1156|M.gilvum_PYR-GCK ALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELAR------VADGAG
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 SVRAVETLIGDRDVDPERLHRITG---GNAFFVCEMLD------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 -------------------------------------------RLAAEVG
Mb1393|M.bovis_AF2122/97 EGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHALGLIDR
Rv1358|M.tuberculosis_H37Rv EGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHALGLIDR
MSMEG_0321|M.smegmatis_MC2_155 TIAGRRSAGRVEDSFTSRVRS-------LPDEARQLLLLAAAEPIG----
TH_3225|M.thermoresistible__bu SPGAGSAPSRIEENYVHRIRA-------LPAQTRRLLLIAAAEPIG----
MAB_3361|M.abscessus_ATCC_1997 WPDGGRLAGQIEQTFLRRVQQ-------LPAHTQTLLLAAATDPLG----
MMAR_0085|M.marinum_M LANATRTETQIERTFVSRLRA-------LPSETKTFLLVAAAESTA----
Mflv_1156|M.gilvum_PYR-GCK SRPGQRLPESLSELVRLRVDG-------LAEDVRDVLLVAASATSP----
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 -HDGADLPTSVRDAILARTAD-------LDAAAWDLLNLLTCAPGAIG--
MUL_2555|M.ulcerans_Agy99 ---MPALSANLVASIDRHPER-----------------------------
MLBr_02341|M.leprae_Br4923 DRDGVDLQLRVGLNSGQVIVG-----------------------------
Mb1393|M.bovis_AF2122/97 PGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPELSILA
Rv1358|M.tuberculosis_H37Rv PGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPELSILA
MSMEG_0321|M.smegmatis_MC2_155 -DAALFVRAAAHLG--------------------VAVPALAPAESAGLIE
TH_3225|M.thermoresistible__bu -DSALFLRAAALMG--------------------IAVDALAPAEAARVIQ
MAB_3361|M.abscessus_ATCC_1997 -DVTLLARAAQQLG--------------------IPMHAIAPAEAADLVE
MMAR_0085|M.marinum_M -RPEWLWAAAHRLG--------------------IGPEAAAPAEAAGLIA
Mflv_1156|M.gilvum_PYR-GCK -TVDLLAKAVGVTP-------------------AAVTGLVEAAEVEGIVV
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 ------DHLLTGLG--------------------VTLPALRALDQAKLIK
MUL_2555|M.ulcerans_Agy99 ----------------------------------ITLRCDDLQSVFAELG
MLBr_02341|M.leprae_Br4923 ------EIGSSALG--------------------YTAVGVQVGMAQRMES
Mb1393|M.bovis_AF2122/97 TSR-ESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVADNFAA
Rv1358|M.tuberculosis_H37Rv TSR-ESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVADNFDA
MSMEG_0321|M.smegmatis_MC2_155 FGT-RIRFHHPLVRSAAYRAASVEDRRAAHHALAEATDAVTDPDRRAWHA
TH_3225|M.thermoresistible__bu FGP-RMRFFHPLMRSAAYRAADPRDRRAVHRALAEATDPGADPDRRAWHA
MAB_3361|M.abscessus_ATCC_1997 LST-RVRFRHPLVRSAVYISANPLERRRIHGVLAGATDPGADPDRRAWHR
MMAR_0085|M.marinum_M AQG-SVRFRHPLIRAAVYHSSSAAERRRVHAALAASIAGPDDDDHRVWHR
Mflv_1156|M.gilvum_PYR-GCK IDGNRIRFTHPVLANGIYAGADPQRRREVHRRLADLKT---DPELRARHL
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 RDARGVAFRHDLCRRAITSVIPPGAEPGLHRRFLDAHRDAHDEDPAVLTH
MUL_2555|M.ulcerans_Agy99 AGPGDRVAALPGDRTRRRVCGPACELS------GGRFRPSARPQSCPGLT
MLBr_02341|M.leprae_Br4923 VAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPR
Mb1393|M.bovis_AF2122/97 VSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGARSTVQ
Rv1358|M.tuberculosis_H37Rv VSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGARSTVQ
MSMEG_0321|M.smegmatis_MC2_155 ANAAAGPSDAVATELEASAGRAQTRGGIAAAATFLERAAVLSADLHLRGA
TH_3225|M.thermoresistible__bu ANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGLRGR
MAB_3361|M.abscessus_ATCC_1997 AHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARGR
MMAR_0085|M.marinum_M AHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHATKLTPDPFVRAS
Mflv_1156|M.gilvum_PYR-GCK ALASTVADETTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVSRRI
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 HALGGGDRALITTAAAQAGRAAARSGAHTQACEFFQIALERGGLLDDGAE
MUL_2555|M.ulcerans_Agy99 EAASPGRSRGPLHLARCAAELTIRRGDACQAIELLRRAGELSDRPRRREQ
MLBr_02341|M.leprae_Br4923 QPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVG----LVGPAGIGKT
Mb1393|M.bovis_AF2122/97 RQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAGGDDF
Rv1358|M.tuberculosis_H37Rv RQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAGGDDF
MSMEG_0321|M.smegmatis_MC2_155 R---------AVAAAQAKRDAADLQAAYELLAIAELSPLSDLQRAQIARL
TH_3225|M.thermoresistible__bu R---------ALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHL
MAB_3361|M.abscessus_ATCC_1997 R---------ALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRL
MMAR_0085|M.marinum_M R---------ALDAAMTSLEAGMPDSATRLVASAAAAADDELIAARCELI
Mflv_1156|M.gilvum_PYR-GCK R------------AAEHHVVAGDMRRAATLLEQALVDLRPGVLCAIALNL
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 A----------ELLERLAEEYYLTDRLEDAISACRRAMRIRRDTRAPVAV
MUL_2555|M.ulcerans_Agy99 L---------LASAAFVALQAAQLDEAERLLADAGLGGGASASALLISSF
MLBr_02341|M.leprae_Br4923 R----------LVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRA
Mb1393|M.bovis_AF2122/97 VERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNESEEI
Rv1358|M.tuberculosis_H37Rv VERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNESEEI
MSMEG_0321|M.smegmatis_MC2_155 RAQMEFSHSRREDSGPAQLRDAAAMLLDAARRLESLDDELALQTHLEAIA
TH_3225|M.thermoresistible__bu RAQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFA
MAB_3361|M.abscessus_ATCC_1997 RAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVG
MMAR_0085|M.marinum_M RAKIAFAASRG--------SDAPPLLLAAAQRMQRLDPSESRKAYLGAVL
Mflv_1156|M.gilvum_PYR-GCK LAGVRMVEDDY---------------IRAVELLERARADADNDAVLVTTL
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 SANHHSLAVYEWYSGNRAVADEHVAEAIAALADVDAEQDPSCLGQLGHGF
MUL_2555|M.ulcerans_Agy99 ISLYRYG-------------------DVTATHRRLVERLQSADDLDGETL
MLBr_02341|M.leprae_Br4923 VAQISGLDDRS----------------ARARVREQIPDADTQDLLLLDDL
Mb1393|M.bovis_AF2122/97 DGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTWSRGN
Rv1358|M.tuberculosis_H37Rv DGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTWSRGN
MSMEG_0321|M.smegmatis_MC2_155 AAMYAGHLGA--PDALLTTAAAAQAAVDRLASRDDPIALLLDGVAKCLTG
TH_3225|M.thermoresistible__bu ALMYAGRLAP--SGALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVG
MAB_3361|M.abscessus_ATCC_1997 AAMYGGRLCP--RGGAVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITH
MMAR_0085|M.marinum_M ASILVGRMATDQHNSSPSVAKAASNAPAAPHP-PRALDVLLDGLVIRLTE
Mflv_1156|M.gilvum_PYR-GCK LSLGFCLGMTGSFTAQLATVREAVAVAERAGVPALTSRALAMWVHVSFQA
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 AMQAFLAVQSSRVDAARKALDRAREIASRAGDPNLSVRVRLIGYYCDISA
MUL_2555|M.ulcerans_Agy99 TRMVNLLLAVSMFAADPALWQITDGLVDSLADRLGELSVIYRDAWADAAR
MLBr_02341|M.leprae_Br4923 LGIADPAVELPRLDPDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEV
Mb1393|M.bovis_AF2122/97 GDIAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLVPAGVWARA
Rv1358|M.tuberculosis_H37Rv GDIAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLVPAGVWARA
MSMEG_0321|M.smegmatis_MC2_155 DVGDAAVPLRKALTAWCSAAQHGD-------------------GAVLPWI
TH_3225|M.thermoresistible__bu GISAAAAPLRVALTAMCELARSRP-------------------AEVVHWL
MAB_3361|M.abscessus_ATCC_1997 GAAASAQTLGEALTLIRCEADR---------------------PANTSWM
MMAR_0085|M.marinum_M GYVAAAPRLRSAIREYLRERDIG-------------------------VA
Mflv_1156|M.gilvum_PYR-GCK GNGLDSAALLRAVDLEDPEDNTP----------------------IPFRA
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 GESLVRDRLLSELAAGPRHIDET---------------------------
MUL_2555|M.ulcerans_Agy99 RGRTVTQRLKEQLDRLAELEPWD---------------------------
MLBr_02341|M.leprae_Br4923 SDSMLADFLAVIPQTRS---------------------------------
Mb1393|M.bovis_AF2122/97 LAEKVILKAWPATSPMGAPDIVAQAHHALALARDAGDCAVLARALVACG-
Rv1358|M.tuberculosis_H37Rv LAEKVILKAWPATSPMGAPDIVAQAHHALALARDAGDCAVLARALVACG-
MSMEG_0321|M.smegmatis_MC2_155 FVGYPIVQESAVDELWDDTLMERLADAMVRYTRDAGALAILPAALSCRAG
TH_3225|M.thermoresistible__bu VPAFPVLQESAGHELWDENLVDALSEAVVRQARDAGALAGLPQALVYRAG
MAB_3361|M.abscessus_ATCC_1997 EQAFPIALESATHEVWDDDMWHHLATRAVHIAREVGALSLLPAALIYRAG
MMAR_0085|M.marinum_M EPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAAGALTMLPVALVTFAG
Mflv_1156|M.gilvum_PYR-GCK SAARGLSLALTGRLAEADGQLAAVAQRSAQRGAEQDVMAVLG----YRTL
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 YSGGYTNLTYYDVEHRRLGEAAAVLGTSIPLMVEHDLPICRVVQLGSRSR
MUL_2555|M.ulcerans_Agy99 ----VMRVALAGYYVDLIDDFRSVLVPLADREIEGGAATIALATLALVAA
MLBr_02341|M.leprae_Br4923 -MALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQ
Mb1393|M.bovis_AF2122/97 -CGSGCDTEAAQPYFAEAIELARAINDEWTLSQIDYWQVVGIFISGQPIP
Rv1358|M.tuberculosis_H37Rv -CGSGCDTEAAQPYFAEAIELARAINDEWTLSQIDYWQVVGIFISGQPIP
MSMEG_0321|M.smegmatis_MC2_155 AHLLSGEFGTAGNLLDEANAIAVAIADQ----PLRYHRLHLAAWRGSTAE
TH_3225|M.thermoresistible__bu VHLLFGEFGLADTLLTEAESITAATDHRG---PVRYHRLIIAAWRGDAVE
MAB_3361|M.abscessus_ATCC_1997 MHVHAGELDAAAELVQEADAISAATGHA----PIRYHSLILAAWRGSEPT
MMAR_0085|M.marinum_M VCVSAGNFGQADALLDESAAIIAATGAP----PRPAIKTYLAAYRGQEQI
Mflv_1156|M.gilvum_PYR-GCK VAIWRGRYAEADAYAADTMERAEQLGGS--MVIAFSICAAVAAYRGREDQ
MAV_5280|M.avium_104 -------------------------------------------MTDPAPE
Mvan_1929|M.vanbaalenii_PYR-1 LNLLVGDWDDALADADAVLNSRSAPLAR-----TWPLLIRGLVALRRTGD
MUL_2555|M.ulcerans_Agy99 YQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDVVR
MLBr_02341|M.leprae_Br4923 IGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPAT
Mb1393|M.bovis_AF2122/97 LRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANGALALSRDVTA
Rv1358|M.tuberculosis_H37Rv LRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANGALALSRDVTA
MSMEG_0321|M.smegmatis_MC2_155 TIAMIDSATAMAHRNGEGRLLAVLGYFAALLYNGAGRYEEAYAAIRPACS
TH_3225|M.thermoresistible__bu AARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIGRYREALAAARTTCE
MAB_3361|M.abscessus_ATCC_1997 AIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACE
MMAR_0085|M.marinum_M CREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGAR
Mflv_1156|M.gilvum_PYR-GCK ARDQAAGALAQGG--DYVALTVWASATLAFLEVSRGNYEQALEAAEPLVD
MAV_5280|M.avium_104 ITVLLVDDQDLVRSGLRRILRRKDGFVIVAECADGDEVPAAVAAHRPDVV
Mvan_1929|M.vanbaalenii_PYR-1 DGGVIDDAWQLARRFGELVRLLPAASAIAERVWLTGTYDKRLDGCHSMLA
MUL_2555|M.ulcerans_Agy99 ARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITA
MLBr_02341|M.leprae_Br4923 LQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDELIDA
Mb1393|M.bovis_AF2122/97 EAEVAN---DVVTKVLGLYVEAMALSYIGDSAARTIAGAALEAATELGGI
Rv1358|M.tuberculosis_H37Rv EAEVAN---DVVTKVLGLYVEAMALSYIGDSAARTIAGAALEAATELGGI
MSMEG_0321|M.smegmatis_MC2_155 TKNLG-----FGGWSLVELIEAAVHTGRREAAEEAAD--RLAAQAGASGT
TH_3225|M.thermoresistible__bu YEDLG-----FYSWCLHELVEAAARVGETDTAHRALG--DIEERAGASGT
MAB_3361|M.abscessus_ATCC_1997 HEDLG-----LYSWCLIELIEAAVRCGEHDTAVKAFG--QLEERALAAQS
MMAR_0085|M.marinum_M YDDVG-----MCGYLLGELIEAAVRCKEHNAATEALG--RLLKRTKASGT
Mflv_1156|M.gilvum_PYR-GCK LYRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIA--AFERNGAELDR
MAV_5280|M.avium_104 VMDLR-----------MRRVDGIEATRRLGGRPPVLALTTFNEDELLSG-
Mvan_1929|M.vanbaalenii_PYR-1 EAPARGLEWARGELGMWLRRIGAADSPVSDVAEPYALLSDGCHEAAAAAF
MUL_2555|M.ulcerans_Agy99 PGEFPP-LALHATRTLFDLVEAAVHTDRLNEARRHVR---AAKRLQFADA
MLBr_02341|M.leprae_Br4923 NLVDQVR---FTAPVEYAFRHPLIRTVAYESQLKSDR--ARLHRRLAAAI
Mb1393|M.bovis_AF2122/97 YQDLGYGAITRAALAAGD----VAAIEASEASWDLRNQHNVVTAHHELMA
Rv1358|M.tuberculosis_H37Rv YQDLGYGAITRAALAAGD----VAAIEASEASWDLRNQHNVVTAHHELMA
MSMEG_0321|M.smegmatis_MC2_155 DWGLGALAGARAMLADHD----TADALFTEAIERLQRTRIAVELARTHLR
TH_3225|M.thermoresistible__bu PWGLGALAGARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLT
MAB_3361|M.abscessus_ATCC_1997 DWSQGMVARSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLI
MMAR_0085|M.marinum_M PTALGIGASATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLT
Mflv_1156|M.gilvum_PYR-GCK PWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALT
MAV_5280|M.avium_104 ----ALRAGAAGFVLKDS-----SAEELIRAVRAVARGEGYLDPAVTSR-
Mvan_1929|M.vanbaalenii_PYR-1 HRLSTPYDAALALVESGE---PAAVRRALDALDRLGADAVANKVRADLRA
MUL_2555|M.ulcerans_Agy99 PPRLAIATGAAEALCASD---ERAPALFEKVLGHPAVASFPFEHARIRLA
MLBr_02341|M.leprae_Br4923 EARAPHSVDQHAVLIAEH---LEAAGDLHAAYGWHMRAAAWATNQDVRAA
: : .
Mb1393|M.bovis_AF2122/97 QAALVRGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGKARD
Rv1358|M.tuberculosis_H37Rv QAALVRGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGKARD
MSMEG_0321|M.smegmatis_MC2_155 YGEWLR---------------------------RVNRRPDARRHLGVA--
TH_3225|M.thermoresistible__bu YGEWLR---------------------------REHRRGEARRELNEA--
MAB_3361|M.abscessus_ATCC_1997 YGEWLR---------------------------RCNRRSDARTELTAA--
MMAR_0085|M.marinum_M YGEWLR---------------------------RERRRSEARSQLRIA--
Mflv_1156|M.gilvum_PYR-GCK LGEVLR----------------------------RLRRRDAAAAVRDA--
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 TGA-----------------------------------------------
MUL_2555|M.ulcerans_Agy99 YGMRLR---------------------------RLRRYRNARVVLRAA--
MLBr_02341|M.leprae_Br4923 RVSWEH--------------------------------------------
Mb1393|M.bovis_AF2122/97 DAHAAVACGVGVQTYLAMPDALELLAGLAGEAGNHGQAVRLFGAAAAQRQ
Rv1358|M.tuberculosis_H37Rv DAHAAVACGVGVQTYLAMPDALELLAGLAGEAGNHGQAVRLFGAAAAQRQ
MSMEG_0321|M.smegmatis_MC2_155 ----------------------------------FDMFTRMGAAGFAERA
TH_3225|M.thermoresistible__bu ----------------------------------HGMFTRMGAQGFAERS
MAB_3361|M.abscessus_ATCC_1997 ----------------------------------HGSFVNMGTAAFAERA
MMAR_0085|M.marinum_M ----------------------------------YDMFAQMGAAGFAERA
Mflv_1156|M.gilvum_PYR-GCK ----------------------------------LAQFEELGVPLWVARA
MAV_5280|M.avium_104 --------------------------------------------------
Mvan_1929|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 ----------------------------------AEIFAGLGAEPWTQRA
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 RTGEVRHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLDEAIAYAQ
Rv1358|M.tuberculosis_H37Rv RTGEVRHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLDEAIAYAQ
MSMEG_0321|M.smegmatis_MC2_155 RR--------------------------------------------ELTA
TH_3225|M.thermoresistible__bu RR--------------------------------------------ELIA
MAB_3361|M.abscessus_ATCC_1997 ER--------------------------------------------ELRA
MMAR_0085|M.marinum_M RR--------------------------------------------ELSA
Mflv_1156|M.gilvum_PYR-GCK RI------------------------------------------------
MAV_5280|M.avium_104 ----------------------------------------------VLTT
Mvan_1929|M.vanbaalenii_PYR-1 ------------------------------------------------TA
MUL_2555|M.ulcerans_Agy99 RN--------------------------------------------ELRA
MLBr_02341|M.leprae_Br4923 -----------------------------------------------ATK
Mb1393|M.bovis_AF2122/97 RGRGERKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVSPRTVQTH
Rv1358|M.tuberculosis_H37Rv RGRGERKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVSPRTVQTH
MSMEG_0321|M.smegmatis_MC2_155 TGEKVRKQPVSSGDELTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWH
TH_3225|M.thermoresistible__bu VGEKVRRQPLTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWH
MAB_3361|M.abscessus_ATCC_1997 TGAKVRKRSASSEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWH
MMAR_0085|M.marinum_M TGEAVYVQPTGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWH
Mflv_1156|M.gilvum_PYR-GCK ALSGLAVSGSAVGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIETN
MAV_5280|M.avium_104 YRKAAPGPHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISGVTVKSH
Mvan_1929|M.vanbaalenii_PYR-1 VPGPRRASTLSNPAGLTVRQVEVLRLLGDGLTNAELAERLFLSVKTVDHH
MUL_2555|M.ulcerans_Agy99 AGTAVRHSAAVGPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAH
MLBr_02341|M.leprae_Br4923 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGD
. : : * . . . . . .
Mb1393|M.bovis_AF2122/97 LTHIYTKLDVTSRVQLVQEAAQHST-----
Rv1358|M.tuberculosis_H37Rv LTHIYTKLDVTSRVQLVQEAAQHST-----
MSMEG_0321|M.smegmatis_MC2_155 LRKVFVKLGIGSRRQLRTIEWAG-------
TH_3225|M.thermoresistible__bu LRKVFVKLGITSRRQLRAAPRVTATW----
MAB_3361|M.abscessus_ATCC_1997 LRKVFAKRGITSRRQLRSGR----------
MMAR_0085|M.marinum_M LSKIFAKLGVTSRRELRAILMESP------
Mflv_1156|M.gilvum_PYR-GCK LSRVYRKLGIRSRAQLGRMLR---------
MAV_5280|M.avium_104 IGRIFGKLDLRDRAAAIVYAYDNGIVAPR-
Mvan_1929|M.vanbaalenii_PYR-1 VSAILTKLDVTKRRDAVRRAREVGILT---
MUL_2555|M.ulcerans_Agy99 LYRLFPKLGVTNRAGLHDALDAIHAAPDQI
MLBr_02341|M.leprae_Br4923 KAPLAVATVGPAIDHVYQDRLH--------
: