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AKPVATRGFARERVLESALELFADHGVSGTSLQMIADRLGVTKAAVYYQFHSKDEITLAVVKPVFDDIEH LLRITETLPTPEARRSVSMSGLVELIIRHRRVSSVFYGDPTVHHLLEGNDEFRRLGDRLADVLLGPDPDT ATRVAISMLSAGIHGCVTDPMIGDVADAELQQILLDLTKAFLDVCVHD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1613 | - | - | 100% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4249 | - | 3e-27 | 37.99% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 5e-24 | 34.73% (167) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 2e-06 | 41.18% (51) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0973 | - | 4e-22 | 33.33% (168) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-06 | 41.18% (51) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 40.35% (57) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2677c | - | 2e-14 | 29.38% (160) | putative trancscriptional regulator,TetR |
| M. marinum M | MMAR_4699 | - | 5e-30 | 40.00% (180) | transcriptional regulatory protein |
| M. avium 104 | MAV_0959 | - | 2e-26 | 38.73% (173) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0227 | - | 5e-59 | 57.22% (187) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 1e-22 | 34.50% (171) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0293 | - | 2e-14 | 30.34% (178) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1613|M.vanbaalenii_PYR-1 -------------------MAKP----------VATRGFARERVLESALE
MSMEG_0227|M.smegmatis_MC2_155 -------------------MAKS----------VAPRGFARERVLEAALN
MMAR_4699|M.marinum_M -------------------MSSQ----SRNQFRVITRSAAQVRILDATLG
MAV_0959|M.avium_104 -------------------MGTARQAVSDEQFWLVEHSPARTRVLDAALD
Mflv_0973|M.gilvum_PYR-GCK -------------------MSGD---------STRAGGPTRRRLIDVAIE
TH_2336|M.thermoresistible__bu -----VSGVGKPISREAALLTSR---------ASAGTGPTRQRLIEVAIE
MAB_2677c|M.abscessus_ATCC_199 -------------------MLSD----------AAVAPGTRERIQTVARD
MUL_0293|M.ulcerans_Agy99 -------------------MVTK----------PRSD--TRRRIQEVARE
Mb1711c|M.bovis_AF2122/97 -------------------MAAPDNS-RRRPGRPAGSSDTRERILSSARE
Rv1685c|M.tuberculosis_H37Rv -------------------MAAPDNS-RRRPGRPAGSSDTRERILSSARE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
: :: :
Mvan_1613|M.vanbaalenii_PYR-1 LFADHGVSGTSLQMIADRLGVTKAAVYYQFHSKDEITLAVVKPVFDDIEH
MSMEG_0227|M.smegmatis_MC2_155 LFAEHGVNGTSLQMIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMRR
MMAR_4699|M.marinum_M LIAEHGVGGTSLQMIADAVGVTKAAVYHQFKTKEQIVIALTERELGGLEE
MAV_0959|M.avium_104 LFAANGVSGTSLQMIADAVGITKAAVYHQFRTKEQIVIAVTERELGRLVP
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
MAB_2677c|M.abscessus_ATCC_199 LFAERGLRNTSLQDIASRLKITKPALYYHFSSRDELVRSIVQPMVDDLQT
MUL_0293|M.ulcerans_Agy99 LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
Mb1711c|M.bovis_AF2122/97 LFAHNGIDRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVI
Rv1685c|M.tuberculosis_H37Rv LFAHNGIDRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVI
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
:: . :.: :: : . :: * :: :: : .
Mvan_1613|M.vanbaalenii_PYR-1 -LLRITETLPTPEARRSVSMSGLVELIIRH-RRVSSVFYGDPTVHHLLEG
MSMEG_0227|M.smegmatis_MC2_155 -VLRIAEAMSSPDARREAAVSGMVELAVRH-RRVSAVFHGDPAIDNLVHS
MMAR_4699|M.marinum_M -ALEAAEAHDHPSQARELLLDRVIELAVER-RGAASTLQFDPVIVRLLAE
MAV_0959|M.avium_104 -ALEEAEAHDDGPQARDALLVRVIEMAVRD-RRLVRTLQFDPVVVRLLAE
Mflv_0973|M.gilvum_PYR-GCK -IVDAAEEQRTPHARADHMLVGYASIAARH-RTLIPLLSGDPGVVALLRT
TH_2336|M.thermoresistible__bu -IVSAAEARRGARTRADHFLRGYAALAAAH-REVISLLTGDPGVVALLRT
MAB_2677c|M.abscessus_ATCC_199 -FLATNN---AGDRR--QLLEDYFDVLWTH-RVVLGIIVRDLAALGQLEL
MUL_0293|M.ulcerans_Agy99 -FVAERERLADGNVR--GLLEGYFDFHYRH-RQDLMLVVVELTLLSDLGL
Mb1711c|M.bovis_AF2122/97 -IGPIREAPVEELGYKLPSLLLPIWDSELG-AGLIATLRSLISGSDVGLA
Rv1685c|M.tuberculosis_H37Rv -IGPIREAPVEELGYKLPSLLLPIWDSELG-AGLIATLRSLISGSDVGLA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
. : .
Mvan_1613|M.vanbaalenii_PYR-1 NDEFRRLGDRLADVLLGPDPDTATRVAISMLSAGIHGCVTD------PMI
MSMEG_0227|M.smegmatis_MC2_155 RKDLHEVIERLTAILLGPEPGTACRVMMSMLASGIFSSAMD------PEL
MMAR_4699|M.marinum_M HQPFQRFIERLYGVLIG-DAGQDTRVLAAMLSGAIAVGVLH------PLV
MAV_0959|M.avium_104 HEPFQRFMDRLYRVLLS-DAGLDGRIEAAMFSGALSTAVMH------PLV
Mflv_0973|M.gilvum_PYR-GCK RSEWGDLVRRQLALFSEVEPGLGGQVKAALAMSGIASAAGV------DYG
TH_2336|M.thermoresistible__bu RPDWAEVVQRQMALLGDVQPGPGGRVKAAVVMAGIAAAAGV------DYG
MAB_2677c|M.abscessus_ATCC_199 GEWMMGWRRRLIVLLAGGKPSAAQMIQATVALGGLSDCT--------IEY
MUL_0293|M.ulcerans_Agy99 IDTVLARRERLGRLVFGAAPTLGQATRAVLAFGGLQDCC--------MQF
Mb1711c|M.bovis_AF2122/97 RSFLEEVVTVELGSRVDNPPGTG-KIRTQFVASQLMGVVMARYIVRIEPF
Rv1685c|M.tuberculosis_H37Rv RSFLEEVVTVELGSRVDNPPGTG-KIRTQFVASQLMGVVMARYIVRIEPF
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
. :
Mvan_1613|M.vanbaalenii_PYR-1 GDVADAELQQILLDLTKAFLDVCVHD--------
MSMEG_0227|M.smegmatis_MC2_155 ADIDDEELHRVLLDCTQRLLNAPVSS--------
MMAR_4699|M.marinum_M ADVDDATLRTQLRRITSRLMDTGEG---------
MAV_0959|M.avium_104 VDIDDETLLDRVTDLSRRLLGLPRKPVE------
Mflv_0973|M.gilvum_PYR-GCK GDVDDDTLRDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu -DLDEAALRDELLAAGRRTLGLR-----APHARG
MAB_2677c|M.abscessus_ATCC_199 ADRPHRQVKKTAVAAAIAALES------------
MUL_0293|M.ulcerans_Agy99 PDEPYAQLRQYSVEAALAALGV------------
Mb1711c|M.bovis_AF2122/97 ASLPAEQIVQTIAPNLQRYLTGELPDDLAP----
Rv1685c|M.tuberculosis_H37Rv ASLPAEQIVQTIAPNLQRYLTGELPDDLAP----
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWGGLSHVPLTRL------
: