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VSSQSRNQFRVITRSAAQVRILDATLGLIAEHGVGGTSLQMIADAVGVTKAAVYHQFKTKEQIVIALTER ELGGLEEALEAAEAHDHPSQARELLLDRVIELAVERRGAASTLQFDPVIVRLLAEHQPFQRFIERLYGVL IGDAGQDTRVLAAMLSGAIAVGVLHPLVADVDDATLRTQLRRITSRLMDTGEG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4699 | - | - | 100% (193) | transcriptional regulatory protein |
| M. marinum M | MMAR_1504 | - | 5e-08 | 27.01% (137) | transcriptional regulatory protein |
| M. marinum M | MMAR_4674 | - | 3e-06 | 45.10% (51) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 1e-06 | 26.90% (171) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0973 | - | 3e-18 | 32.93% (164) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 2e-06 | 27.22% (158) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 3e-05 | 25.35% (71) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0483c | - | 3e-09 | 43.55% (62) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0959 | - | 2e-60 | 63.59% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0227 | - | 2e-32 | 41.67% (180) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 2e-19 | 35.15% (165) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0293 | - | 2e-06 | 45.10% (51) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4249 | - | 3e-66 | 67.57% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4699|M.marinum_M -----------------------MSSQSRNQFRVITRSAAQVRILDATLG
Mvan_4249|M.vanbaalenii_PYR-1 -----------------------MTTAG-TRFSAITRTAAQTRVLDAALD
MAV_0959|M.avium_104 -------------------MGTARQAVSDEQFWLVEHSPARTRVLDAALD
MSMEG_0227|M.smegmatis_MC2_155 ------------------------MAKS-----VAPRGFARERVLEAALN
Mflv_0973|M.gilvum_PYR-GCK ----------------------------MSGDSTRAGGPTRRRLIDVAIE
TH_2336|M.thermoresistible__bu --------------VSGVGKPISREAALLTSRASAGTGPTRQRLIEVAIE
MUL_0293|M.ulcerans_Agy99 -------------------------------MVTKPRSDTRRRIQEVARE
Rv0078|M.tuberculosis_H37Rv -------------------------MEIKRRTQEERSAATREALITGARK
MAB_0483c|M.abscessus_ATCC_199 ------------------------MSETKARRQDRRTAVTTAAILDAAEG
Mb0310|M.bovis_AF2122/97 -------------------------MGVPAKKKQQQGERSRESILDATER
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
: :
MMAR_4699|M.marinum_M LIAEHGVGGTSLQMIADAVGVTKAAVYHQFKTKEQIVIALTERELGGLEE
Mvan_4249|M.vanbaalenii_PYR-1 LISEHGVSGTSLQMIADSMGVTKAAVYRQFKSKDDIVIALTEREFGRLED
MAV_0959|M.avium_104 LFAANGVSGTSLQMIADAVGITKAAVYHQFRTKEQIVIAVTERELGRLVP
MSMEG_0227|M.smegmatis_MC2_155 LFAEHGVNGTSLQMIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMRR
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
MUL_0293|M.ulcerans_Agy99 LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
Rv0078|M.tuberculosis_H37Rv LWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMA
MAB_0483c|M.abscessus_ATCC_199 LFAERGFHAVTVDAIAEAAGLAVGSIYHHFKNKERLYLALVERALSVNEQ
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: . . * *:: :* :* : : :
MMAR_4699|M.marinum_M ---ALEAAEAHDHPSQARELLLDRVIELAVERRGAASTLQF-------DP
Mvan_4249|M.vanbaalenii_PYR-1 ---ALEAAEAEESAPRARELLLNQVIDEAIERRRHVATLQF-------DP
MAV_0959|M.avium_104 ---ALEEAEAHDDGPQARDALLVRVIEMAVRDRRLVRTLQF-------DP
MSMEG_0227|M.smegmatis_MC2_155 ---VLRIAEAMSSPDARREAAVSGMVELAVRHRRVSAVFHG-------DP
Mflv_0973|M.gilvum_PYR-GCK ---IVDAAEEQRTPHARADHMLVGYASIAARHRTLIPLLSG-------DP
TH_2336|M.thermoresistible__bu ---IVSAAEARRGARTRADHFLRGYAALAAAHREVISLLTG-------DP
MUL_0293|M.ulcerans_Agy99 ---FVAERERLADGNVR--GLLEGYFDFHYRHRQDLMLVVV-------EL
Rv0078|M.tuberculosis_H37Rv RMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLD-------AP
MAB_0483c|M.abscessus_ATCC_199 --AMAVAFGQGRTPMEELRAASDAYCDFHLQNPGYFRMIAL-------RT
Mb0310|M.bovis_AF2122/97 --AIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDP
MLBr_00815|M.leprae_Br4923 --SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFE------NDN
.
MMAR_4699|M.marinum_M VIVRLLA--EHQPFQRFIERLYGVLIG-DAGQD--------TRVLAAMLS
Mvan_4249|M.vanbaalenii_PYR-1 VIIKFLA--SHQPFQAFIARLYAVLVG-DAGRE--------AKLTAAMLS
MAV_0959|M.avium_104 VVVRLLA--EHEPFQRFMDRLYRVLLS-DAGLD--------GRIEAAMFS
MSMEG_0227|M.smegmatis_MC2_155 AIDNLVH--SRKDLHEVIERLTAILLGPEPGTA--------CRVMMSMLA
Mflv_0973|M.gilvum_PYR-GCK GVVALLR--TRSEWGDLVRRQLALFSEVEPGLG--------GQVKAALAM
TH_2336|M.thermoresistible__bu GVVALLR--TRPDWAEVVQRQMALLGDVQPGPG--------GRVKAAVVM
MUL_0293|M.ulcerans_Agy99 TLLSDLG--LIDTVLARRERLGRLVFGAAPTLG--------QATRAVLAF
Rv0078|M.tuberculosis_H37Rv VVLGWAG--FRDVAQRYSLGMTEQLITEAIRAGQLARQP--VRPLAQVLI
MAB_0483c|M.abscessus_ATCC_199 LDVPPGD--MADEVERRIADKVEALVGDIADVLRRADAAGEVHCPDPVRV
Mb0310|M.bovis_AF2122/97 VVAAVVRRVRNTAIARFRDSITHLLPSDIPPGK-----ADLVVAELTAFA
MLBr_00815|M.leprae_Br4923 ITEPRVAAQVRVATESCIDAVFALISADSRLDPHR------ARMVAVGLV
.
MMAR_4699|M.marinum_M GAIAVGVLHPLVADVDDATLRTQLRRITSRLMDTGEG---------
Mvan_4249|M.vanbaalenii_PYR-1 GAIAVGVMHPLVADIDDDTLRRELLHYTRRLIDLPE----------
MAV_0959|M.avium_104 GALSTAVMHPLVVDIDDETLLDRVTDLSRRLLGLPRKPVE------
MSMEG_0227|M.smegmatis_MC2_155 SGIFSSAMDPELADIDDEELHRVLLDCTQRLLNAPVSS--------
Mflv_0973|M.gilvum_PYR-GCK SGIASAAGVDYGGDVDDDTLRDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu AGIAAAAGVDYG-DLDEAALRDELLAAGRRTLGLR-----APHARG
MUL_0293|M.ulcerans_Agy99 GGLQDCCM--QFPDEPYAQLRQYSVEAALAALGV------------
Rv0078|M.tuberculosis_H37Rv GALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG---------
MAB_0483c|M.abscessus_ATCC_199 SIFLWGAWNGVLSLNLRPDRLRLEPAEMQRVLELGRDIIERGLVRT
Mb0310|M.bovis_AF2122/97 VALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET----
MLBr_00815|M.leprae_Br4923 GISVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----