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VTKPRSDTRRRIQEVARELFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGERFV AERERLADGNVRGLLEGYFDFHYRHRQDLMLVVVELTLLSDLGLIDTVLARRERLGRLVFGAAPTLGQAT RAVLAFGGLQDCCMQFPDEPYAQLRQYSVEAALAALGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0293 | - | - | 100% (179) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_4765 | - | 5e-08 | 46.30% (54) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2529 | - | 7e-08 | 26.47% (102) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 5e-08 | 28.43% (102) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0973 | - | 7e-18 | 37.18% (156) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 5e-08 | 28.43% (102) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-07 | 26.73% (101) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2677c | - | 5e-38 | 47.93% (169) | putative trancscriptional regulator,TetR |
| M. marinum M | MMAR_4674 | - | 1e-96 | 99.44% (178) | transcriptional regulator |
| M. avium 104 | MAV_0985 | - | 1e-60 | 75.82% (153) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5718 | - | 1e-64 | 72.00% (175) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 1e-15 | 32.78% (180) | transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 4e-16 | 48.28% (87) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0293|M.ulcerans_Agy99 -------------------------------MVTKPRSDTRRRIQEVARE
MMAR_4674|M.marinum_M --------------------------------MTKPRSDTRRRIQEVARE
MAV_0985|M.avium_104 --------------------------------------------------
MSMEG_5718|M.smegmatis_MC2_155 -------------------------------------MDTRQRIQEVARE
MAB_2677c|M.abscessus_ATCC_199 -----------------------------MLSDAAVAPGTRERIQTVARD
Mflv_0973|M.gilvum_PYR-GCK --------------------------MSGDSTRAGGP--TRRRLIDVAIE
TH_2336|M.thermoresistible__bu ------------VSGVGKPISREAALLTSRASAGTGP--TRQRLIEVAIE
Mvan_0170|M.vanbaalenii_PYR-1 --------------------------MTTASSAQMPPQSARQRVLDVALA
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MUL_0293|M.ulcerans_Agy99 LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
MMAR_4674|M.marinum_M LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
MAV_0985|M.avium_104 ------MQRTSLQDIADRLGITKPALYYHFPSREDLVRSILVPLIEEGER
MSMEG_5718|M.smegmatis_MC2_155 LFAEKGVVRTSLQDIADRLGITKPALYYHFRSREELIRSILQPLIDEGEA
MAB_2677c|M.abscessus_ATCC_199 LFAERGLRNTSLQDIASRLKITKPALYYHFSSRDELVRSIVQPMVDDLQT
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
Mvan_0170|M.vanbaalenii_PYR-1 LFTRHGYAGTSLQMIADEMGVTKGSLYYHFRAREDLLRALVGPLIEQLRA
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
:.:: *:. ::* :* ** :: :* ::: : :
MUL_0293|M.ulcerans_Agy99 FVAERERL---ADGNVRGLLEGYFDFHYRHRQDLMLVVVELTLLSDLGLI
MMAR_4674|M.marinum_M FVAERERL---ADGNVRGLLEGYFDFHYRHRQDLMLVVVELTLLSDLGLI
MAV_0985|M.avium_104 FVAEHESR---EHTEARELLEGYFDFHYRHRRDLVLLLTELSTLIDLDLI
MSMEG_5718|M.smegmatis_MC2_155 FVAEQERKRAADRASARELLEGYFDFHYRHRADLVLIVSELTTLVDLGLI
MAB_2677c|M.abscessus_ATCC_199 FLATNNAG------DRRQLLEDYFDVLWTHRVVLGIIVRDLAALGQLELG
Mflv_0973|M.gilvum_PYR-GCK IVDAAEEQRT-PHARADHMLVGYASIAARHRTLIPLLSGDPGVVALLRTR
TH_2336|M.thermoresistible__bu IVSAAEARRG-ARTRADHFLRGYAALAAAHREVISLLTGDPGVVALLRTR
Mvan_0170|M.vanbaalenii_PYR-1 IVEHAEAQRS-PSVRAEHVLTGYARLAAANRALVAVTSGDPSVVEVIHAD
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
: : : . . : :
MUL_0293|M.ulcerans_Agy99 DTVLARRERLGRLVFGAAPTL-GQATRAVLAFGGLQDCC---MQFP-DEP
MMAR_4674|M.marinum_M DTVLAWRERLGRLVFGAAPTL-GQATRAVLAFGGLQDCC---MQFP-DEP
MAV_0985|M.avium_104 DTVLAWRERLARLVFGKRPTL-AQSTRAVVAFGGLQDCC---VQFP-DAP
MSMEG_5718|M.smegmatis_MC2_155 DQLLAWRARLGALVFGRTPTL-EQSTRAVIAFGGLQDCC---LQFP-DVP
MAB_2677c|M.abscessus_ATCC_199 EWMMGWRRRLIVLLAGGKPSA-AQMIQATVALGGLSDCT---IEYA-DRP
Mflv_0973|M.gilvum_PYR-GCK SEWGDLVRRQLALFSEVEPGL-GGQVKAALAMSGIASAAG--VDYGGDVD
TH_2336|M.thermoresistible__bu PDWAEVVQRQMALLGDVQPGP-GGRVKAAVVMAGIAAAAG--VDYG-DLD
Mvan_0170|M.vanbaalenii_PYR-1 PDWADLIDRQIGLLAAVQPGL-AGRVRATIVMAGIAATAA--PGVV-EAD
Mb3233|M.bovis_AF2122/97 QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
Rv3208|M.tuberculosis_H37Rv QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
:. . :* : *: :
MUL_0293|M.ulcerans_Agy99 YAQLRQYSVEAALAALGV------------
MMAR_4674|M.marinum_M YAQLRQYSVEAALAALGV------------
MAV_0985|M.avium_104 QAELRDKSVAAALDALGERPRR--------
MSMEG_5718|M.smegmatis_MC2_155 AEQLRTATVNGAMAALGL------------
MAB_2677c|M.abscessus_ATCC_199 HRQVKKTAVAAAIAALES------------
Mflv_0973|M.gilvum_PYR-GCK DDTLRDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu EAALRDELLAAGRRTLGLR-----APHARG
Mvan_0170|M.vanbaalenii_PYR-1 EAELCRQLIDAGRRTLGLR-----APRA--
Mb3233|M.bovis_AF2122/97 KPISKSDAVEGTVQFAWGGLSHVPLTRS--
Rv3208|M.tuberculosis_H37Rv KPISKSDAVEGTVQFAWGGLSHVPLTRS--
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWGGLSHVPLTRL--
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