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VAKSVAPRGFARERVLEAALNLFAEHGVNGTSLQMIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMR RVLRIAEAMSSPDARREAAVSGMVELAVRHRRVSAVFHGDPAIDNLVHSRKDLHEVIERLTAILLGPEPG TACRVMMSMLASGIFSSAMDPELADIDDEELHRVLLDCTQRLLNAPVSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0227 | - | - | 100% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6537 | - | 1e-29 | 39.34% (183) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5718 | - | 3e-12 | 37.36% (91) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 3e-07 | 29.84% (124) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0973 | - | 6e-28 | 33.71% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 3e-07 | 29.84% (124) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 5e-07 | 25.00% (184) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2677c | - | 7e-13 | 30.46% (151) | putative trancscriptional regulator,TetR |
| M. marinum M | MMAR_4699 | - | 2e-32 | 41.67% (180) | transcriptional regulatory protein |
| M. avium 104 | MAV_0959 | - | 3e-30 | 40.91% (176) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 3e-29 | 35.16% (182) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0293 | - | 3e-15 | 34.00% (150) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1613 | - | 4e-59 | 57.22% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0227|M.smegmatis_MC2_155 -------------------MAKS----------VAPRGFARERVLEAALN
Mvan_1613|M.vanbaalenii_PYR-1 -------------------MAKP----------VATRGFARERVLESALE
MMAR_4699|M.marinum_M -------------------MSSQ----SRNQFRVITRSAAQVRILDATLG
MAV_0959|M.avium_104 -------------------MGTARQAVSDEQFWLVEHSPARTRVLDAALD
Mflv_0973|M.gilvum_PYR-GCK -------------------MSGD---------STRAGGPTRRRLIDVAIE
TH_2336|M.thermoresistible__bu -----VSGVGKPISREAALLTSR---------ASAGTGPTRQRLIEVAIE
MAB_2677c|M.abscessus_ATCC_199 -------------------MLSD----------AAVAPGTRERIQTVARD
MUL_0293|M.ulcerans_Agy99 -------------------MVTK----------PRSD--TRRRIQEVARE
Mb3198c|M.bovis_AF2122/97 ----------------MPPVTRTTE------PPRRGGRGARQRILKAAAE
Rv3173c|M.tuberculosis_H37Rv ----------------MPPVTRTTE------PPRRGGRGARQRILKAAAE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
: :: :
MSMEG_0227|M.smegmatis_MC2_155 LFAEHGVNGTSLQMIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMRR
Mvan_1613|M.vanbaalenii_PYR-1 LFADHGVSGTSLQMIADRLGVTKAAVYYQFHSKDEITLAVVKPVFDDIEH
MMAR_4699|M.marinum_M LIAEHGVGGTSLQMIADAVGVTKAAVYHQFKTKEQIVIALTERELGGLEE
MAV_0959|M.avium_104 LFAANGVSGTSLQMIADAVGITKAAVYHQFRTKEQIVIAVTERELGRLVP
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
MAB_2677c|M.abscessus_ATCC_199 LFAERGLRNTSLQDIASRLKITKPALYYHFSSRDELVRSIVQPMVDDLQT
MUL_0293|M.ulcerans_Agy99 LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
Mb3198c|M.bovis_AF2122/97 LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE
Rv3173c|M.tuberculosis_H37Rv LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
:: . :.:: *:. ::* .:* :* :: :
MSMEG_0227|M.smegmatis_MC2_155 -VLRIAEAMSSPDARREAAVSGMVELAVR-------HRRVSAVFHGDPAI
Mvan_1613|M.vanbaalenii_PYR-1 -LLRITETLPTPEARRSVSMSGLVELIIR-------HRRVSSVFYGDPTV
MMAR_4699|M.marinum_M -ALEAAEAHDHPSQARELLLDRVIELAVE-------RRGAASTLQFDPVI
MAV_0959|M.avium_104 -ALEEAEAHDDGPQARDALLVRVIEMAVR-------DRRLVRTLQFDPVV
Mflv_0973|M.gilvum_PYR-GCK -IVDAAEEQRTPHARADHMLVGYASIAAR-------HRTLIPLLSGDPGV
TH_2336|M.thermoresistible__bu -IVSAAEARRGARTRADHFLRGYAALAAA-------HREVISLLTGDPGV
MAB_2677c|M.abscessus_ATCC_199 -FLATNN---AGDRR--QLLEDYFDVLWT-------HRVVLGIIVRDLAA
MUL_0293|M.ulcerans_Agy99 -FVAERERLADGNVR--GLLEGYFDFHYR-------HRQDLMLVVVELTL
Mb3198c|M.bovis_AF2122/97 -ADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGV
Rv3173c|M.tuberculosis_H37Rv -ADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGV
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHD------GQGYRLIFENDNIT
. : .
MSMEG_0227|M.smegmatis_MC2_155 DNLVHSRK-DLHEVIERLTAILLGPEPGTACRVMMSMLASGIFSSAMDPE
Mvan_1613|M.vanbaalenii_PYR-1 HHLLEGND-EFRRLGDRLADVLLGPDPDTATRVAISMLSAGIHGCVTDPM
MMAR_4699|M.marinum_M VRLLAEHQ-PFQRFIERLYGVLIG-DAGQDTRVLAAMLSGAIAVGVLHPL
MAV_0959|M.avium_104 VRLLAEHE-PFQRFMDRLYRVLLS-DAGLDGRIEAAMFSGALSTAVMHPL
Mflv_0973|M.gilvum_PYR-GCK VALLRTRS-EWGDLVRRQLALFSEVEPGLGGQVKAALAMSGIASAAGVDY
TH_2336|M.thermoresistible__bu VALLRTRP-DWAEVVQRQMALLGDVQPGPGGRVKAAVVMAGIAAAAGVDY
MAB_2677c|M.abscessus_ATCC_199 LGQLELGE-WMMGWRRRLIVLLAGGKPSAAQMIQATVALGGLSDCT--IE
MUL_0293|M.ulcerans_Agy99 LSDLGLID-TVLARRERLGRLVFGAAPTLGQATRAVLAFGGLQDCC--MQ
Mb3198c|M.bovis_AF2122/97 ERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDD
Rv3173c|M.tuberculosis_H37Rv ERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDD
MLBr_00815|M.leprae_Br4923 EPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCAR
: . : .
MSMEG_0227|M.smegmatis_MC2_155 LADIDDEELHRVLLDCTQRLLNAPVSS--------
Mvan_1613|M.vanbaalenii_PYR-1 IGDVADAELQQILLDLTKAFLDVCVHD--------
MMAR_4699|M.marinum_M VADVDDATLRTQLRRITSRLMDTGEG---------
MAV_0959|M.avium_104 VVDIDDETLLDRVTDLSRRLLGLPRKPVE------
Mflv_0973|M.gilvum_PYR-GCK GGDVDDDTLRDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu G-DLDEAALRDELLAAGRRTLGLR-----APHARG
MAB_2677c|M.abscessus_ATCC_199 YADRPHRQVKKTAVAAAIAALES------------
MUL_0293|M.ulcerans_Agy99 FPDEPYAQLRQYSVEAALAALGV------------
Mb3198c|M.bovis_AF2122/97 AGPWAHARAAAEVLIDQATARPV------------
Rv3173c|M.tuberculosis_H37Rv AGPWAHARAAAEVLIDQATARPV------------
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-